ATE89314T1 - Menschlicher metallothionein ii-promotor in saeugetierexpressionssystemen. - Google Patents
Menschlicher metallothionein ii-promotor in saeugetierexpressionssystemen.Info
- Publication number
- ATE89314T1 ATE89314T1 AT86901613T AT86901613T ATE89314T1 AT E89314 T1 ATE89314 T1 AT E89314T1 AT 86901613 T AT86901613 T AT 86901613T AT 86901613 T AT86901613 T AT 86901613T AT E89314 T1 ATE89314 T1 AT E89314T1
- Authority
- AT
- Austria
- Prior art keywords
- promotor
- produced
- human metallothionein
- expression systems
- mammalian expression
- Prior art date
Links
- 101001014059 Homo sapiens Metallothionein-2 Proteins 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108091026890 Coding region Proteins 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- 108700028146 Genetic Enhancer Elements Proteins 0.000 abstract 1
- 102000002265 Human Growth Hormone Human genes 0.000 abstract 1
- 108010000521 Human Growth Hormone Proteins 0.000 abstract 1
- 239000000854 Human Growth Hormone Substances 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000001817 pituitary effect Effects 0.000 abstract 1
- 239000012679 serum free medium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
- C12N9/6486—Renin (3.4.23.15)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/23—Aspartic endopeptidases (3.4.23)
- C12Y304/23015—Renin (3.4.23.15)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Plant Pathology (AREA)
- Cardiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70129685A | 1985-02-13 | 1985-02-13 | |
| US80167485A | 1985-11-25 | 1985-11-25 | |
| EP86901613A EP0217822B1 (de) | 1985-02-13 | 1986-02-11 | Menschlicher metallothionein ii-promotor in säugetierexpressionssystemen |
| PCT/US1986/000296 WO1986004920A1 (en) | 1985-02-13 | 1986-02-11 | Human metallothionein-ii promoter in mammalian expression system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE89314T1 true ATE89314T1 (de) | 1993-05-15 |
Family
ID=27106764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86901613T ATE89314T1 (de) | 1985-02-13 | 1986-02-11 | Menschlicher metallothionein ii-promotor in saeugetierexpressionssystemen. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5089397A (de) |
| EP (1) | EP0217822B1 (de) |
| AT (1) | ATE89314T1 (de) |
| AU (1) | AU580145B2 (de) |
| CA (1) | CA1338829C (de) |
| DE (1) | DE3688418T2 (de) |
| DK (1) | DK488386A (de) |
| ES (1) | ES8707564A1 (de) |
| WO (1) | WO1986004920A1 (de) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4659805A (en) * | 1984-12-11 | 1987-04-21 | California Biotechnology, Inc. | Recombinant alveolar surfactant protein |
| IL78314A0 (en) * | 1985-04-03 | 1986-07-31 | Biotechnology Res Ass | Expression vectors and methods for the production of recombinant human renin |
| EP0240550A4 (de) * | 1985-09-26 | 1989-09-19 | Genetics Inst | Lungen-oberflachenaktive proteine. |
| WO1987002062A1 (en) * | 1985-10-04 | 1987-04-09 | Biotechnology Research Partners, Ltd. | Recombinant apolipoproteins and methods |
| DK173067B1 (da) * | 1986-06-27 | 1999-12-13 | Univ Washington | Humant erythropoietin-gen, fremgangsmåde til ekspression deraf i transficerede cellelinier, de transficerede cellelinier sa |
| AU613876B2 (en) * | 1986-10-01 | 1991-08-15 | Merck & Co., Inc. | Synthetic genes encoding proteins from plasmid containing eucaryotic secretory signal peptides and process for secreting encoded proteins |
| GB8625435D0 (en) * | 1986-10-23 | 1986-11-26 | Erba Farmitalia | Human apolipoprotein ai |
| GB8629153D0 (en) * | 1986-12-05 | 1987-01-14 | Ciba Geigy Ag | Hybrid proteins |
| US6048729A (en) | 1987-05-01 | 2000-04-11 | Transkaryotic Therapies, Inc. | In vivo protein production and delivery system for gene therapy |
| GB8712540D0 (en) | 1987-05-28 | 1987-07-01 | Ucb Sa | Expression of human proapolipoprotein a-i |
| US5830685A (en) * | 1990-02-09 | 1998-11-03 | Genentech, Inc. | Method of producing proteins using mammalian lung cell lines |
| GB9022543D0 (en) * | 1990-10-17 | 1990-11-28 | Wellcome Found | Antibody production |
| US6063630A (en) * | 1991-11-05 | 2000-05-16 | Transkaryotic Therapies, Inc. | Targeted introduction of DNA into primary or secondary cells and their use for gene therapy |
| NZ245015A (en) | 1991-11-05 | 1995-12-21 | Transkaryotic Therapies Inc | Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production |
| US6054288A (en) * | 1991-11-05 | 2000-04-25 | Transkaryotic Therapies, Inc. | In vivo protein production and delivery system for gene therapy |
| US6692737B1 (en) | 1991-11-05 | 2004-02-17 | Transkaryotic Therapies, Inc. | In vivo protein production and delivery system for gene therapy |
| JP2524939B2 (ja) * | 1991-12-03 | 1996-08-14 | 株式会社ニチレイ | エンハンサ−及びその用途 |
| US5342782A (en) * | 1992-02-24 | 1994-08-30 | Washington University | Tightly regulated expression system for eucaryotic cells |
| US6670178B1 (en) | 1992-07-10 | 2003-12-30 | Transkaryotic Therapies, Inc. | In Vivo production and delivery of insulinotropin for gene therapy |
| US6531124B1 (en) | 1992-07-10 | 2003-03-11 | Transkaryotic Therapies, Inc. | In vivo production and delivery of insulinotropin for gene therapy |
| FR2704556B1 (fr) * | 1993-04-30 | 1995-07-13 | Rhone Poulenc Rorer Sa | Virus recombinants et leur utilisation en thérapie génique. |
| US5962664A (en) * | 1993-05-13 | 1999-10-05 | Friedhoff; Arnold J. | Psychosis protecting nucleic acid, peptides, compositions and method of use |
| JPH07163368A (ja) * | 1993-12-15 | 1995-06-27 | Hayashibara Biochem Lab Inc | 組換えｄｎａとその組換えｄｎａを含む形質転換体 |
| GB9506051D0 (en) * | 1995-03-24 | 1995-05-10 | Univ Singapore | Gene expression |
| AUPN442295A0 (en) * | 1995-07-26 | 1995-08-17 | Commonwealth Scientific And Industrial Research Organisation | Regulated autocrine growth of mammalian cells |
| US6297027B1 (en) | 1996-07-31 | 2001-10-02 | Purina Mills, Inc. | Bovine leptin protein, nucleic acid sequences coding therefor and uses thereof |
| US6277592B1 (en) | 1996-07-31 | 2001-08-21 | Purina Mills, Inc. | Porcine leptin protein, nucleic acid sequences coding therefor and uses thereof |
| EP2221361A3 (de) | 1996-08-30 | 2011-02-09 | Life Technologies Corporation | Methode zur Herstellung eines Polypeptids in vitro in einer Säugerzelle in einem Kulturmedium ohne Serum und ohne Proteine |
| US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
| AU753106B2 (en) * | 1998-04-22 | 2002-10-10 | Cornell Research Foundation Inc. | Canine erythropoietin gene and recombinant protein |
| US6696411B1 (en) | 1998-04-22 | 2004-02-24 | Cornell Research Foundation, Inc. | Canine erythropoietin gene and recombinant protein |
| AT409379B (de) | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| US20020127654A1 (en) * | 2001-02-22 | 2002-09-12 | Price Virginia L. | Compositions and methods for production cell culture |
| WO2002095061A1 (en) * | 2001-05-18 | 2002-11-28 | New York University | Methods of screening test substances for treating or preventing diseases involving an oxidative stress |
| DK1520008T3 (da) | 2002-07-09 | 2012-10-15 | Baxter Int | Medium frit for dyreprotein til dyrkning af celler |
| EP1828768A4 (de) * | 2004-08-13 | 2009-05-06 | Jaguar Bioscience Inc | Systeme und verfahren zur identifizierung diagnostischer indikatoren |
| US20060094104A1 (en) | 2004-10-29 | 2006-05-04 | Leopold Grillberger | Animal protein-free media for cultivation of cells |
| ES2361559T3 (es) * | 2004-11-02 | 2011-06-20 | Ares Trading S.A. | Medio de cultivo de células exento de suero para mamíferos. |
| EP1907561B1 (de) * | 2005-06-24 | 2013-08-28 | Unigene Laboratories, Inc. | Zellinien zur expression eines bei der herstellung amidierter produkte geeigneten enzyms |
| ES2474573T3 (es) | 2006-01-04 | 2014-07-09 | Baxter International Inc | Medio de cultivo celular sin oligop�ptidos |
| PT2592148T (pt) | 2007-10-12 | 2018-11-12 | Hoffmann La Roche | Expressão proteica de múltiplos ácidos nucleicos |
| ES2337973B8 (es) | 2008-05-16 | 2011-07-21 | Proyecto De Biomedicina Cima, S.L. | Adenovirus auxiliares auto-inactivantes para la produccion de adenovirus recombinantes de alta capacidad. |
| ES2330826B1 (es) | 2008-06-04 | 2010-07-26 | Proyecto De Biomedicina Cima, S.L. | Sistema para empaquetamiento de adenovirus de alta capacidad. |
| EP3699172A3 (de) | 2008-11-10 | 2020-11-18 | Arbutus Biopharma Corporation | Neuartige lipide und zusammensetzungen zur verabreichung von therapeutika |
| EP2391343B1 (de) | 2009-01-29 | 2017-03-01 | Arbutus Biopharma Corporation | Verbesserte lipidformulierung zur verabreichung von nukleinsaueren |
| CA2754043A1 (en) | 2009-03-12 | 2010-09-16 | Alnylam Pharmaceuticals, Inc. | Lipid formulated compositions and methods for inhibiting expression of eg5 and vegf genes |
| CA3042927C (en) | 2009-05-05 | 2022-05-17 | Arbutus Biopharma Corporation | Lipid compositions for the delivery of therapeutic agents |
| KR20220038506A (ko) | 2009-06-10 | 2022-03-28 | 알닐람 파마슈티칼스 인코포레이티드 | 향상된 지질 조성물 |
| US9029338B2 (en) | 2009-08-14 | 2015-05-12 | Alnylam Pharmaceuticals, Inc. | Lipid formulated compositions and methods for inhibiting expression of a gene from the ebola virus |
| US9540426B2 (en) * | 2009-10-06 | 2017-01-10 | Bristol-Myers Squibb Company | Mammalian cell culture processes for protein production |
| CA3044884A1 (en) | 2009-12-07 | 2011-06-16 | Arbutus Biopharma Corporation | Compositions for nucleic acid delivery |
| US20130017223A1 (en) | 2009-12-18 | 2013-01-17 | The University Of British Columbia | Methods and compositions for delivery of nucleic acids |
| WO2011139911A2 (en) | 2010-04-29 | 2011-11-10 | Isis Pharmaceuticals, Inc. | Lipid formulated single stranded rna |
| WO2011143362A1 (en) | 2010-05-11 | 2011-11-17 | Esperion Therapeutics, Inc. | Dimeric oxidation-resistant apolipoprotein a1 variants |
| EP4481047A3 (de) | 2010-06-03 | 2025-04-16 | Alnylam Pharmaceuticals, Inc. | Biologisch abbaubare lipide zur freisetzung von wirkstoffen |
| EP2407534A1 (de) | 2010-07-14 | 2012-01-18 | Neo Virnatech, S.L. | Verfahren und Reagenzien zum Erhalt von transkriptionell aktiven virusähnlichen Artikeln und rekombinante Virionen |
| WO2012016188A2 (en) | 2010-07-30 | 2012-02-02 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for delivery of active agents |
| WO2012016184A2 (en) | 2010-07-30 | 2012-02-02 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for delivery of active agents |
| ES2562274T3 (es) | 2010-10-06 | 2016-03-03 | Fundació Institut De Recerca Biomèdica (Irb Barcelona) | Procedimiento para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de mama |
| US9339513B2 (en) | 2010-11-09 | 2016-05-17 | Alnylam Pharmaceuticals, Inc. | Lipid formulated compositions and methods for inhibiting expression of Eg5 and VEGF genes |
| US9999673B2 (en) | 2011-01-11 | 2018-06-19 | Alnylam Pharmaceuticals, Inc. | PEGylated lipids and their use for drug delivery |
| JP6250543B2 (ja) | 2011-09-27 | 2017-12-20 | アルニラム・ファーマシューティカルズ・インコーポレーテッド | ジ脂肪族置換ｐｅｇ化脂質 |
| EP2650682A1 (de) | 2012-04-09 | 2013-10-16 | Fundació Privada Institut de Recerca Biomèdica | Asymmetrische Ester von als Schmiermittel geeigneten Fettsäuren |
| EP3467124A1 (de) | 2012-06-06 | 2019-04-10 | Fundació Institut de Recerca Biomèdica IRB (Barcelona) | Verfahren zur diagnose, prognose und behandlung von lungenkrebsmetastasen |
| WO2014011908A1 (en) | 2012-07-11 | 2014-01-16 | Esperion Therapeutics, Inc. | Apolipoprotein mixtures |
| EP2687852A1 (de) | 2012-07-17 | 2014-01-22 | Laboratorios Del. Dr. Esteve, S.A. | Verfahren zur Diagnose und Behandlung des chronischen Erschöpfungssyndroms |
| CA2888122A1 (en) | 2012-10-12 | 2014-04-17 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis using c-maf |
| KR20150122786A (ko) | 2013-03-15 | 2015-11-02 | 펀다시오 인스티튜트 드 르세르카 바이오메디카 (아이알비 바르셀로나) | 암 전이의 진단, 예후 및 치료를 위한 방법 |
| US20160032399A1 (en) | 2013-03-15 | 2016-02-04 | Inbiomotion S.L. | Method for the Prognosis and Treatment of Renal Cell Carcinoma Metastasis |
| US20160032400A1 (en) | 2013-03-15 | 2016-02-04 | Fundació Institut De Recerca Biomèdica (Irb Barcelona) | Method for the prognosis and treatment of cancer metastasis |
| ES2523016B1 (es) | 2013-05-20 | 2015-09-09 | 3P Biopharmaceuticals | Vectores alfavirales y líneas celulares para la producción de proteínas recombinantes |
| EP3524698A1 (de) | 2013-10-09 | 2019-08-14 | Fundació Institut de Recerca Biomèdica IRB (Barcelona) | Verfahren zur prognose und behandlung von krebsmetastasen |
| EP3089755A1 (de) | 2014-01-03 | 2016-11-09 | Fundacion Biofisica Bizkaia | Vlps, verfahren zu deren gewinnung und anwendungen davon |
| KR101867134B1 (ko) * | 2015-03-23 | 2018-06-12 | 한양대학교 산학협력단 | 포유류 세포를 이용하여 목적 물질을 고효율로 생산하기 위한 세포 배양 배지, 이를 이용한 세포 배양 방법 및 목적 물질의 생산 방법 |
| KR20190124270A (ko) | 2017-03-10 | 2019-11-04 | 에프. 호프만-라 로슈 아게 | 다중특이적 항체의 생산 방법 |
| PT115073A (pt) | 2018-10-09 | 2020-05-29 | Inst De Biologia Molecular E Celular Ibmc | Ácido nucleico para ativar a expressão e a produção de proteínas |
| EP4371569A1 (de) | 2022-11-16 | 2024-05-22 | Universidad del País Vasco/Euskal Herriko Unibertsitatea | Vlps gegen akute myeloische leukämie |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4399216A (en) * | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| ATE72583T1 (de) * | 1981-11-23 | 1992-02-15 | University Patents Inc | Steuerung der dna-sequenzen-transkription. |
| US4446235A (en) * | 1982-03-22 | 1984-05-01 | Genentech, Inc. | Method for cloning human growth hormone varient genes |
| US4601978A (en) * | 1982-11-24 | 1986-07-22 | The Regents Of The University Of California | Mammalian metallothionein promoter system |
| JPS60500358A (ja) * | 1982-12-23 | 1985-03-22 | アメリカ合衆国 | マウスの細胞内で組み換えｄｎａによって生産されたヒト成長ホルモン |
| US4703008A (en) * | 1983-12-13 | 1987-10-27 | Kiren-Amgen, Inc. | DNA sequences encoding erythropoietin |
-
1986
- 1986-02-11 AT AT86901613T patent/ATE89314T1/de not_active IP Right Cessation
- 1986-02-11 EP EP86901613A patent/EP0217822B1/de not_active Expired - Lifetime
- 1986-02-11 WO PCT/US1986/000296 patent/WO1986004920A1/en not_active Ceased
- 1986-02-11 DE DE8686901613T patent/DE3688418T2/de not_active Expired - Lifetime
- 1986-02-11 AU AU55135/86A patent/AU580145B2/en not_active Expired
- 1986-02-12 ES ES551913A patent/ES8707564A1/es not_active Expired
- 1986-02-13 CA CA000501798A patent/CA1338829C/en not_active Expired - Lifetime
- 1986-10-13 DK DK488386A patent/DK488386A/da not_active Application Discontinuation
-
1989
- 1989-06-14 US US07/366,342 patent/US5089397A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3688418D1 (de) | 1993-06-17 |
| ES8707564A1 (es) | 1987-08-01 |
| DK488386A (da) | 1986-12-15 |
| AU580145B2 (en) | 1989-01-05 |
| AU5513586A (en) | 1986-09-10 |
| DK488386D0 (da) | 1986-10-13 |
| DE3688418T2 (de) | 1993-08-26 |
| EP0217822A1 (de) | 1987-04-15 |
| EP0217822B1 (de) | 1993-05-12 |
| WO1986004920A1 (en) | 1986-08-28 |
| ES551913A0 (es) | 1987-08-01 |
| EP0217822A4 (de) | 1989-05-11 |
| CA1338829C (en) | 1997-01-07 |
| US5089397A (en) | 1992-02-18 |
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