ATE90969T1 - Expression von fremden genen in drosophilazellen. - Google Patents

Expression von fremden genen in drosophilazellen.

Info

Publication number
ATE90969T1
ATE90969T1 AT88304093T AT88304093T ATE90969T1 AT E90969 T1 ATE90969 T1 AT E90969T1 AT 88304093 T AT88304093 T AT 88304093T AT 88304093 T AT88304093 T AT 88304093T AT E90969 T1 ATE90969 T1 AT E90969T1
Authority
AT
Austria
Prior art keywords
foreign genes
expression
drosophila cells
drosophila
cells
Prior art date
Application number
AT88304093T
Other languages
English (en)
Inventor
Hanne Ranch Johansen
Der Straten-Ponthoz Ariane Van
Martin Rosenberg
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE90969T1 publication Critical patent/ATE90969T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1145—Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/75—Vector systems having a special element relevant for transcription from invertebrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT88304093T 1987-05-08 1988-05-06 Expression von fremden genen in drosophilazellen. ATE90969T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4773687A 1987-05-08 1987-05-08
EP88304093A EP0290261B1 (de) 1987-05-08 1988-05-06 Expression von fremden Genen in Drosophila-Zellen

Publications (1)

Publication Number Publication Date
ATE90969T1 true ATE90969T1 (de) 1993-07-15

Family

ID=21950656

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88304093T ATE90969T1 (de) 1987-05-08 1988-05-06 Expression von fremden genen in drosophilazellen.

Country Status (12)

Country Link
EP (1) EP0290261B1 (de)
JP (1) JP2706260B2 (de)
AT (1) ATE90969T1 (de)
AU (1) AU618952B2 (de)
CA (1) CA1341345C (de)
CY (1) CY1929A (de)
DE (1) DE3881953T2 (de)
DK (1) DK175595B1 (de)
ES (1) ES2058274T3 (de)
IE (1) IE63005B1 (de)
PT (1) PT87424B (de)
ZA (1) ZA883213B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01108995A (ja) * 1987-10-23 1989-04-26 Hoechst Japan Kk 培養動物細胞による蛋白質の産生を向上させるための遺伝子増幅方法
CA2003794C (en) * 1988-12-01 2000-02-08 Hanne R. Johansen Expression of hiv proteins in drosophila cells
JPH03504082A (ja) * 1988-12-21 1991-09-12 スミスクライン・バイオロジカルズ 昆虫細胞によるプラスモディウム属サーカムスポロゾイト蛋白の発現

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79202B (de) * 1982-05-05 1984-10-22 Genentech Inc
AU572108B2 (en) * 1983-01-19 1988-05-05 Genentech Inc. Human tpa production using vectors coding for dhfr protein
AU593264B2 (en) * 1985-07-10 1990-02-08 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Chromosomal DNA sequence, expression vector for human tissue plasminogen activating factor, cultured cells transfected with same and method of producing said activating factor
JP2515299B2 (ja) * 1986-06-03 1996-07-10 三井東圧化学株式会社 ヒ−トシヨツクたんぱく質遺伝子ｈｓｐ８３を含む発現ベクタ−及びこれを用いる誘導的発現

Also Published As

Publication number Publication date
JPS63304982A (ja) 1988-12-13
EP0290261B1 (de) 1993-06-23
DE3881953D1 (de) 1993-07-29
PT87424A (pt) 1989-05-31
AU618952B2 (en) 1992-01-16
DK175595B1 (da) 2004-12-13
ES2058274T3 (es) 1994-11-01
DK243388A (da) 1988-11-09
IE63005B1 (en) 1995-03-22
ZA883213B (en) 1989-03-29
DK243388D0 (da) 1988-05-04
CY1929A (en) 1997-05-16
AU1551088A (en) 1988-11-10
EP0290261A1 (de) 1988-11-09
IE881373L (en) 1988-11-08
HK1006852A1 (en) 1999-03-19
JP2706260B2 (ja) 1998-01-28
DE3881953T2 (de) 1993-09-30
CA1341345C (en) 2002-03-05
PT87424B (pt) 1992-09-30

Similar Documents

Publication Publication Date Title
FI862756A0 (fi) Fibroektiner.
ES2061512T3 (es) Polipeptidos de nor-estatina y nor-cicloestatina.
ATE123787T1 (de) Herstellung von peroxid enthaltenden perfluorpolyäthern.
FI864331A7 (fi) Transformaatio ja vieraiden geenien ilmaiseminen puulajeilla.
DE3854223D1 (de) Erzeugung und Anzeige von Rechnergraphiken.
DK155318C (da) Indoxyl- og thioindoxyl-aminosyreestere og -peptidestere, diagnostisk middel indeholdende dem, og deres anvendelse i diagnostiske midler
ATE312190T1 (de) Nukleinsaeure enthaltende zusammensetzungen, herstellung und verwendung
FI943122A0 (fi) Menetelmiä trombiinin tuottamiseksi
DK0506791T3 (da) Enzymholdigt præparat og detergent indeholdende et sådant præparat
DE69334211D1 (de) Multidrug resistenz gen
ATE78399T1 (de) Verwendung von buspiron zur verbesserung des kurzzeitgedaechtnisses.
FI870818A7 (fi) Ihmisen normaaleista paksusuolen soluista saatu kudosplasminogeeni-aktivaattori.
DE3869230D1 (de) Verfahren zur herstellung einer loesung hoher spezifischer volumenaktivitaet von einem protein mit gewebe-plasminogenaktivator (t-pa)-aktivitaet, loesung, enthaltend protein mit t-pa-aktivitaet und verwendung der loesung in der human- und veterinaermedizin.
DD130489A5 (de) Bruehe zur anzeige des vorliegens von candida-hefe und anderen pilzen
DE3480718D1 (de) Expression von pflanzlichen strukturellen genen.
ATE90969T1 (de) Expression von fremden genen in drosophilazellen.
ATE116368T1 (de) Vektoren und verbindungen zur expression von zymogen-formen von menschlichem protein c.
DE3781667D1 (de) Verwendung von 24,25-dihydroxycholecalciferol zur verhuetung des knochenalterns.
NO307612B1 (no) Fremgangsmåte for fremstilling av en vevstypeplasminogen- aktivatorvariant
DE3675063D1 (de) Mischungen von polycaprolactonpolyolen und polyepoxyden.
DE59309254D1 (de) Verwendung von Prothrombinfragmenten
DE68905638D1 (de) Herstellung von alkansulfonylhaliden und alkansulfonsaeuren.
KR890701732A (ko) 개량형 조직 플라스미노겐 활성화 인자
DE3888505D1 (de) Herstellung von Zimtsäureestern.
DE59003265D1 (de) Verwendung von nor-verapamil und nor-gallopamil als antiarteriosklerotica.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time