|
US5116964A
(en)
*
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
US6406697B1
(en)
|
1989-02-23 |
2002-06-18 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
US5225538A
(en)
*
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
|
DE69012950T2
(de)
*
|
1989-10-13 |
1995-03-16 |
Takara Shuzo Co |
Antikrebsmittel.
|
|
US5610148A
(en)
*
|
1991-01-18 |
1997-03-11 |
University College London |
Macroscopically oriented cell adhesion protein for wound treatment
|
|
US5629287A
(en)
*
|
1991-01-18 |
1997-05-13 |
University College London |
Depot formulations
|
|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2719593B1
(fr)
*
|
1994-05-06 |
1996-05-31 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur préparation et composition pharmaceutique les contenant.
|
|
US5641483A
(en)
*
|
1995-06-07 |
1997-06-24 |
Beaulieu; Andre |
Wound healing formulations containing human plasma fibronectin
|
|
US5877149A
(en)
|
1995-06-07 |
1999-03-02 |
Beaulieu; Andre |
Deepithelialized skin diffusion cell system
|
|
US6528483B2
(en)
|
1995-06-07 |
2003-03-04 |
André Beaulieu |
Method of producing concentrated non-buffered solutions of fibronectin
|
|
US7112320B1
(en)
|
1995-06-07 |
2006-09-26 |
Andre Beaulieu |
Solid wound healing formulations containing fibronectin
|
|
JP3192067B2
(ja)
*
|
1995-10-09 |
2001-07-23 |
科学技術振興事業団 |
ペプチドとコラーゲン収縮阻害剤
|
|
GB9526733D0
(en)
|
1995-12-30 |
1996-02-28 |
Delta Biotechnology Ltd |
Fusion proteins
|
|
US5922676A
(en)
*
|
1996-09-20 |
1999-07-13 |
The Burnham Institute |
Methods of inhibiting cancer by using superfibronectin
|
|
EP2206720A1
(de)
|
2000-04-12 |
2010-07-14 |
Human Genome Sciences, Inc. |
Albuminfusionsproteine
|
|
US6946134B1
(en)
|
2000-04-12 |
2005-09-20 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
AU2001286688A1
(en)
*
|
2000-08-25 |
2002-03-13 |
Human Genome Sciences, Inc. |
Tumor necrosis factor receptors 6alpha and 6beta
|
|
BR0116024A
(pt)
|
2000-12-07 |
2005-12-13 |
Lilly Co Eli |
Proteìna de fusão heteróloga e uso da mesma
|
|
US7507413B2
(en)
|
2001-04-12 |
2009-03-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
EP2261250B1
(de)
|
2001-12-21 |
2015-07-01 |
Human Genome Sciences, Inc. |
GCSF-Albumin Fusionsproteine
|
|
US20060002935A1
(en)
|
2002-06-28 |
2006-01-05 |
Domantis Limited |
Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor
|
|
GB0217033D0
(en)
|
2002-07-23 |
2002-08-28 |
Delta Biotechnology Ltd |
Gene and polypeptide sequences
|
|
CA2513213C
(en)
|
2003-01-22 |
2013-07-30 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
KR20070084069A
(ko)
|
2004-10-08 |
2007-08-24 |
도만티스 리미티드 |
Tnfr1에 대한 단일 도메인 항체 및 이의 사용 방법
|
|
EA015860B1
(ru)
|
2005-10-13 |
2011-12-30 |
Хьюман Дженом Сайенсиз, Инк. |
Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа
|
|
WO2007061896A1
(en)
|
2005-11-17 |
2007-05-31 |
Zogenix, Inc. |
Delivery of viscous formulations by needle-free injection
|
|
EP1816201A1
(de)
|
2006-02-06 |
2007-08-08 |
CSL Behring GmbH |
Modifizierter Koagulationsfaktor VIIa mit verbesserter 'half-life'-Stabiltät
|
|
US8268347B1
(en)
|
2006-10-24 |
2012-09-18 |
Aradigm Corporation |
Dual action, inhaled formulations providing both an immediate and sustained release profile
|
|
MX2009011870A
(es)
|
2007-05-02 |
2009-11-12 |
Ambrx Inc |
Polipeptidos de interferon beta modificados y usos de los mismos.
|
|
CA2688433A1
(en)
|
2007-06-06 |
2008-12-11 |
Domantis Limited |
Methods for selecting protease resistant polypeptides
|
|
MX2010005317A
(es)
|
2007-11-20 |
2010-06-02 |
Ambrx Inc |
Polipeptidos de insulina modificados y sus usos.
|
|
AU2009241847B2
(en)
|
2008-04-28 |
2014-07-10 |
Zogenix, Inc. |
Novel formulations for treatment of migraine
|
|
PL2274331T3
(pl)
|
2008-05-02 |
2014-04-30 |
Novartis Ag |
Ulepszone cząsteczki wiążące oparte na fibronektynie i ich zastosowanie
|
|
PT2318029T
(pt)
|
2008-07-23 |
2018-01-10 |
Ambrx Inc |
Polipéptidos de g-csf bovino modificados e suas utilizações
|
|
CN102282168A
(zh)
|
2008-11-18 |
2011-12-14 |
梅里麦克制药股份有限公司 |
人血清白蛋白接头以及其结合物
|
|
KR101740066B1
(ko)
|
2008-12-05 |
2017-05-25 |
글락소 그룹 리미티드 |
프로테아제 저항성 폴리펩티드를 선택하는 방법
|
|
CN102405236A
(zh)
|
2009-02-19 |
2012-04-04 |
葛兰素集团有限公司 |
改进的抗-tnfr1多肽,抗体可变结构域和拮抗剂
|
|
WO2010138555A2
(en)
|
2009-05-26 |
2010-12-02 |
University Of Florida Research Foundation, Inc. |
Small peptide expression system in mammalian cells
|
|
EP2453920A2
(de)
|
2009-07-16 |
2012-05-23 |
Glaxo Group Limited |
Antagonisten, verwendung und verfahren zur teilweisen tnfr1-hemmung
|
|
BR112012010114A2
(pt)
|
2009-10-27 |
2017-08-08 |
Glaxo Group Ltd |
domínio variável único de imunoglobulina, ligante multiespecífico, antagonista, uso do antagonista, método para tratamento e/ou profilaxia de uma condição inflamatória em um paciente, ácido nucleico, vetor, e, célula hospedeira.
|
|
WO2011051466A1
(en)
|
2009-11-02 |
2011-05-05 |
Novartis Ag |
Anti-idiotypic fibronectin-based binding molecules and uses thereof
|
|
NZ600361A
(en)
|
2009-12-21 |
2014-06-27 |
Ambrx Inc |
Modified bovine somatotropin polypeptides and their uses
|
|
JP2013515081A
(ja)
|
2009-12-21 |
2013-05-02 |
アンブルックス,インコーポレイテッド |
修飾されているブタのソマトトロピンポリペプチドおよびそれらの使用
|
|
WO2011092233A1
(en)
|
2010-01-29 |
2011-08-04 |
Novartis Ag |
Yeast mating to produce high-affinity combinations of fibronectin-based binders
|
|
EP4234698A3
(de)
|
2010-05-06 |
2023-11-08 |
Novartis AG |
Zusammensetzungen und verfahren zur verwendung von therapeutischen antikörpern gegen ldl-assoziiertes protein 6 (lrp6)
|
|
UA126265C2
(uk)
|
2010-07-09 |
2022-09-14 |
Байовератів Терапьютікс Інк. |
Поліпептид фактора іх і спосіб його застосування
|
|
MA34521B1
(fr)
|
2010-08-17 |
2013-09-02 |
Ambrx Inc |
Polypeptides de relaxine modifiés et leurs utilisations
|
|
NZ607337A
(en)
|
2010-08-20 |
2015-06-26 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (her3)
|
|
EP2625264B1
(de)
|
2010-10-08 |
2022-12-07 |
Terumo BCT, Inc. |
Verfahren und systeme für züchtung und ernte von zellen in einem hohlfaser-bioreaktorsystem mit steuerungsbedingungen
|
|
US20130245233A1
(en)
|
2010-11-24 |
2013-09-19 |
Ming Lei |
Multispecific Molecules
|
|
EP2726502A1
(de)
|
2011-07-01 |
2014-05-07 |
Bayer Intellectual Property GmbH |
Relaxin-fusionspolypeptide und ihre verwendung
|
|
JP2014529293A
(ja)
|
2011-07-08 |
2014-11-06 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
レラキシンを放出する融合タンパク質およびその使用
|
|
CN104039830A
(zh)
|
2011-11-04 |
2014-09-10 |
诺华股份有限公司 |
低密度脂蛋白相关蛋白6(lrp6)-半寿期延长物构建体
|
|
AU2012349735B2
(en)
|
2011-12-05 |
2016-05-19 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (HER3)
|
|
KR20140103135A
(ko)
|
2011-12-05 |
2014-08-25 |
노파르티스 아게 |
Her3의 도메인 ii에 대해 지시된 표피 성장 인자 수용체 3 (her3)에 대한 항체
|
|
WO2013170636A1
(zh)
|
2012-05-18 |
2013-11-21 |
爱德迪安(北京)生物技术有限公司 |
用于糖尿病治疗的蛋白、蛋白缀合物及其应用
|
|
US20150202287A1
(en)
|
2012-08-30 |
2015-07-23 |
Merrimack Pharmaceuticals, Inc. |
Combination therapies comprising anti-erbb3 agents
|
|
US10981961B2
(en)
|
2013-03-11 |
2021-04-20 |
University Of Florida Research Foundation, Incorporated |
Delivery of card protein as therapy for occular inflammation
|
|
EP2970479B1
(de)
|
2013-03-14 |
2019-04-24 |
Novartis AG |
Antikörper gegen notch 3
|
|
JP6633522B2
(ja)
|
2013-11-16 |
2020-01-22 |
テルモ ビーシーティー、インコーポレーテッド |
バイオリアクターにおける細胞増殖
|
|
CN112043835B
(zh)
|
2013-12-06 |
2022-10-21 |
韩捷 |
用于含氮和羟基的药物的生物可逆引入基团
|
|
WO2015148704A1
(en)
|
2014-03-25 |
2015-10-01 |
Terumo Bct, Inc. |
Passive replacement of media
|
|
EP3157947A1
(de)
|
2014-06-23 |
2017-04-26 |
Novartis AG |
Hsa-gdf-15-fusionspolypeptid und verwendung davon
|
|
US20160090569A1
(en)
|
2014-09-26 |
2016-03-31 |
Terumo Bct, Inc. |
Scheduled Feed
|
|
KR20250078598A
(ko)
|
2015-05-19 |
2025-06-02 |
예일 유니버시티 |
병리학적 석회화 병태를 치료하기 위한 조성물, 및 이의 사용 방법
|
|
WO2017004592A1
(en)
|
2015-07-02 |
2017-01-05 |
Terumo Bct, Inc. |
Cell growth with mechanical stimuli
|
|
CN108367053A
(zh)
|
2015-12-22 |
2018-08-03 |
诺华股份有限公司 |
使用生长分化因子15(gdf-15)治疗或改善代谢性疾病的方法
|
|
WO2017125897A1
(en)
|
2016-01-21 |
2017-07-27 |
Novartis Ag |
Multispecific molecules targeting cll-1
|
|
JP7034949B2
(ja)
|
2016-05-25 |
2022-03-14 |
テルモ ビーシーティー、インコーポレーテッド |
細胞の増殖
|
|
US11685883B2
(en)
|
2016-06-07 |
2023-06-27 |
Terumo Bct, Inc. |
Methods and systems for coating a cell growth surface
|
|
US11104874B2
(en)
|
2016-06-07 |
2021-08-31 |
Terumo Bct, Inc. |
Coating a bioreactor
|
|
US12234441B2
(en)
|
2017-03-31 |
2025-02-25 |
Terumo Bct, Inc. |
Cell expansion
|
|
CN117247899A
(zh)
|
2017-03-31 |
2023-12-19 |
泰尔茂比司特公司 |
细胞扩增
|
|
US11624046B2
(en)
|
2017-03-31 |
2023-04-11 |
Terumo Bct, Inc. |
Cell expansion
|
|
UY38251A
(es)
|
2018-06-01 |
2019-12-31 |
Novartis Ag |
Moléculas de unión contra bcma y usos de las mismas
|
|
EP3887393A1
(de)
|
2018-11-26 |
2021-10-06 |
Novartis AG |
Lpl-gpihbp1 fusionspolypeptide
|
|
US20220098252A1
(en)
|
2019-01-25 |
2022-03-31 |
Ospedale San Raffaele S.R.L. |
Inhibitor of dux4 and uses thereof
|
|
EP3972993A1
(de)
|
2019-05-21 |
2022-03-30 |
Novartis AG |
Variante cd58-domänen und deren verwendungen
|
|
PE20220568A1
(es)
|
2019-05-21 |
2022-04-20 |
Novartis Ag |
Moleculas de union a cd19 y usos de las mismas
|
|
CN114341195B
(zh)
|
2019-09-06 |
2025-04-25 |
诺华股份有限公司 |
治疗性融合蛋白
|
|
US20240025993A1
(en)
|
2020-11-06 |
2024-01-25 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
GB2619893A
(en)
|
2021-03-23 |
2023-12-20 |
Terumo Bct Inc |
Cell capture and expansion
|
|
US12152699B2
(en)
|
2022-02-28 |
2024-11-26 |
Terumo Bct, Inc. |
Multiple-tube pinch valve assembly
|
|
US20230357381A1
(en)
|
2022-04-26 |
2023-11-09 |
Novartis Ag |
Multispecific antibodies targeting il-13 and il-18
|
|
USD1099116S1
(en)
|
2022-09-01 |
2025-10-21 |
Terumo Bct, Inc. |
Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device
|
|
EP4389762A1
(de)
|
2022-12-23 |
2024-06-26 |
Ospedale San Raffaele S.r.l. |
Inhibitoren der dux4-aktivität und ihre therapeutische verwendung.
|
|
CN116574173B
(zh)
*
|
2023-06-25 |
2026-04-17 |
浙江诸暨聚源生物技术有限公司 |
蛋白稳定性增强的重组人源纤连蛋白突变体及其表达菌株
|
|
WO2026058155A1
(en)
|
2024-09-11 |
2026-03-19 |
Novartis Ag |
Antibodies targeting il-31
|