ATE94388T1 - Verwendung von otiloniumbromid fuer die topische anwendung im gastrointestinaltrakt und entsprechende geeignete pharmazeutische formulierung. - Google Patents
Verwendung von otiloniumbromid fuer die topische anwendung im gastrointestinaltrakt und entsprechende geeignete pharmazeutische formulierung.Info
- Publication number
- ATE94388T1 ATE94388T1 AT87830386T AT87830386T ATE94388T1 AT E94388 T1 ATE94388 T1 AT E94388T1 AT 87830386 T AT87830386 T AT 87830386T AT 87830386 T AT87830386 T AT 87830386T AT E94388 T1 ATE94388 T1 AT E94388T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical formulation
- gastrointestinal tract
- topical application
- appropriate pharmaceutical
- otilonium bromide
- Prior art date
Links
- VWZPIJGXYWHBOW-UHFFFAOYSA-N otilonium bromide Chemical compound [Br-].CCCCCCCCOC1=CC=CC=C1C(=O)NC1=CC=C(C(=O)OCC[N+](C)(CC)CC)C=C1 VWZPIJGXYWHBOW-UHFFFAOYSA-N 0.000 title abstract 3
- 210000001035 gastrointestinal tract Anatomy 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229960000426 otilonium bromide Drugs 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- 210000002249 digestive system Anatomy 0.000 abstract 1
- 230000004899 motility Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Endoscopes (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8609514A IT1216283B (it) | 1986-11-04 | 1986-11-04 | Utilizzazione di ottilonio bromuro (dci) per applicazione topica nel tratto gastro-intestinale e relativa formulazione farmaceutica appropriata per tale uso. |
| EP87830386A EP0270503B1 (de) | 1986-11-04 | 1987-11-03 | Verwendung von Otiloniumbromid für die topische Anwendung im Gastrointestinaltrakt und entsprechende geeignete pharmazeutische Formulierung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE94388T1 true ATE94388T1 (de) | 1993-10-15 |
Family
ID=11131395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87830386T ATE94388T1 (de) | 1986-11-04 | 1987-11-03 | Verwendung von otiloniumbromid fuer die topische anwendung im gastrointestinaltrakt und entsprechende geeignete pharmazeutische formulierung. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4978772A (de) |
| EP (1) | EP0270503B1 (de) |
| JP (1) | JP2514670B2 (de) |
| AT (1) | ATE94388T1 (de) |
| CA (1) | CA1311419C (de) |
| DE (1) | DE3787448T2 (de) |
| ES (1) | ES2058138T3 (de) |
| IT (1) | IT1216283B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100503889B1 (ko) * | 2002-07-20 | 2005-07-26 | 한국과학기술연구원 | 옥틸로늄 브로마이드를 함유하는 항암제 흡수 증진제 |
| WO2010092436A1 (en) * | 2009-02-12 | 2010-08-19 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | Pharmaceutical combinations of simethicone and otilonium |
| EP2481395A1 (de) | 2011-02-01 | 2012-08-01 | Deva Holding Anonim Sirketi | Sachet, Brausetabletten und Sirup Trockensubstanz Formulierungen von Otilonium |
| EP2481403A1 (de) | 2011-02-01 | 2012-08-01 | Deva Holding Anonim Sirketi | Pharmazeutische kombination von Otilonium mit Trimebutine |
| WO2016200345A1 (en) | 2015-06-12 | 2016-12-15 | Santa Farma İlaç Sanayi̇ A. Ş. | Oral pharmaceutical composition comprising otilonium bromide and simethicone with certain bulk density and improved dissolution characteristics. |
-
1986
- 1986-11-04 IT IT8609514A patent/IT1216283B/it active
-
1987
- 1987-10-27 CA CA000550314A patent/CA1311419C/en not_active Expired - Lifetime
- 1987-11-03 DE DE87830386T patent/DE3787448T2/de not_active Expired - Fee Related
- 1987-11-03 ES ES87830386T patent/ES2058138T3/es not_active Expired - Lifetime
- 1987-11-03 EP EP87830386A patent/EP0270503B1/de not_active Expired - Lifetime
- 1987-11-03 AT AT87830386T patent/ATE94388T1/de active
- 1987-11-04 JP JP62277534A patent/JP2514670B2/ja not_active Expired - Lifetime
- 1987-11-04 US US07/117,751 patent/US4978772A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT8609514A0 (it) | 1986-11-04 |
| DE3787448T2 (de) | 1994-01-13 |
| EP0270503A2 (de) | 1988-06-08 |
| JP2514670B2 (ja) | 1996-07-10 |
| IT1216283B (it) | 1990-02-22 |
| ES2058138T3 (es) | 1994-11-01 |
| CA1311419C (en) | 1992-12-15 |
| EP0270503A3 (en) | 1990-04-18 |
| JPS63130530A (ja) | 1988-06-02 |
| DE3787448D1 (de) | 1993-10-21 |
| US4978772A (en) | 1990-12-18 |
| EP0270503B1 (de) | 1993-09-15 |
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