IT1216283B - Utilizzazione di ottilonio bromuro (dci) per applicazione topica nel tratto gastro-intestinale e relativa formulazione farmaceutica appropriata per tale uso. - Google Patents

Utilizzazione di ottilonio bromuro (dci) per applicazione topica nel tratto gastro-intestinale e relativa formulazione farmaceutica appropriata per tale uso.

Info

Publication number: IT1216283B
Authority: IT; Italy
Prior art keywords: pharmaceutical formulation; octilonium; gastro; dci; bromide
Prior art date: 1986-11-04

Application number

IT8609514A

Other languages

English (en)

Other versions

IT8609514A0 (it

Inventor

Casini Alessandro

Parti Sandro

Bucci Paolo

Original Assignee

Menarini Sas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-04

Filing date

1986-11-04

Publication date

1990-02-22

1986-11-04 Application filed by Menarini Sas filed Critical Menarini Sas

1986-11-04 Priority to IT8609514A priority Critical patent/IT1216283B/it

1986-11-04 Publication of IT8609514A0 publication Critical patent/IT8609514A0/it

1987-10-27 Priority to CA000550314A priority patent/CA1311419C/en

1987-11-03 Priority to AT87830386T priority patent/ATE94388T1/de

1987-11-03 Priority to DE87830386T priority patent/DE3787448T2/de

1987-11-03 Priority to ES87830386T priority patent/ES2058138T3/es

1987-11-03 Priority to EP87830386A priority patent/EP0270503B1/en

1987-11-04 Priority to US07/117,751 priority patent/US4978772A/en

1987-11-04 Priority to JP62277534A priority patent/JP2514670B2/ja

1990-02-22 Application granted granted Critical

1990-02-22 Publication of IT1216283B publication Critical patent/IT1216283B/it

Links

210000001035 gastrointestinal tract Anatomy 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 title 2
230000000699 topical effect Effects 0.000 title 1
VWZPIJGXYWHBOW-UHFFFAOYSA-N otilonium bromide Chemical compound [Br-].CCCCCCCCOC1=CC=CC=C1C(=O)NC1=CC=C(C(=O)OCC[N+](C)(CC)CC)C=C1 VWZPIJGXYWHBOW-UHFFFAOYSA-N 0.000 abstract 2
210000002249 digestive system Anatomy 0.000 abstract 1
230000004899 motility Effects 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Physiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Emergency Medicine (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nutrition Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Endoscopes (AREA)
Steroid Compounds (AREA)

IT8609514A 1986-11-04 1986-11-04 Utilizzazione di ottilonio bromuro (dci) per applicazione topica nel tratto gastro-intestinale e relativa formulazione farmaceutica appropriata per tale uso. IT1216283B (it)

Priority Applications (8)

Application Number	Priority Date	Filing Date	Title
IT8609514A IT1216283B (it)	1986-11-04	1986-11-04	Utilizzazione di ottilonio bromuro (dci) per applicazione topica nel tratto gastro-intestinale e relativa formulazione farmaceutica appropriata per tale uso.
CA000550314A CA1311419C (en)	1986-11-04	1987-10-27	Utilization of otilonium bromide for topical application in the gastrointestinal tract and pharmaceutical formulations appropriate for such use
AT87830386T ATE94388T1 (de)	1986-11-04	1987-11-03	Verwendung von otiloniumbromid fuer die topische anwendung im gastrointestinaltrakt und entsprechende geeignete pharmazeutische formulierung.
DE87830386T DE3787448T2 (de)	1986-11-04	1987-11-03	Verwendung von Otiloniumbromid für die topische Anwendung im Gastrointestinaltrakt und entsprechende geeignete pharmazeutische Formulierung.
ES87830386T ES2058138T3 (es)	1986-11-04	1987-11-03	Utilizacion de bromuro de otilonio (dci) para aplicacion topica en el tracto gastrointestinal y formulacion farmaceutica correspondiente apropiada de un uso de esta indole.
EP87830386A EP0270503B1 (en)	1986-11-04	1987-11-03	Utilization of bromure d'otilonium (dci) for topic application in the gastrointestinal tract and relative pharmaceutical formulation appropriate for such use
US07/117,751 US4978772A (en)	1986-11-04	1987-11-04	Utilization of otilonium bromide (DCI) for topical application in the gastroinstestinal tract and related pharmaceutical formulation appropriate for such use
JP62277534A JP2514670B2 (ja)	1986-11-04	1987-11-04	オチロニウムブロマイド含有製薬組成物

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8609514A IT1216283B (it)	1986-11-04	1986-11-04	Utilizzazione di ottilonio bromuro (dci) per applicazione topica nel tratto gastro-intestinale e relativa formulazione farmaceutica appropriata per tale uso.

Publications (2)

Publication Number	Publication Date
IT8609514A0 IT8609514A0 (it)	1986-11-04
IT1216283B true IT1216283B (it)	1990-02-22

Family

ID=11131395

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT8609514A IT1216283B (it)	1986-11-04	1986-11-04	Utilizzazione di ottilonio bromuro (dci) per applicazione topica nel tratto gastro-intestinale e relativa formulazione farmaceutica appropriata per tale uso.

Country Status (8)

Country	Link
US (1)	US4978772A (it)
EP (1)	EP0270503B1 (it)
JP (1)	JP2514670B2 (it)
AT (1)	ATE94388T1 (it)
CA (1)	CA1311419C (it)
DE (1)	DE3787448T2 (it)
ES (1)	ES2058138T3 (it)
IT (1)	IT1216283B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100503889B1 (ko) *	2002-07-20	2005-07-26	한국과학기술연구원	옥틸로늄 브로마이드를 함유하는 항암제 흡수 증진제
TR201111221T2 (tr) *	2009-02-12	2012-02-21	Abd� �Brah�M �La� Sanay� Ve T�Caret Anon�M ��Rket�@	Simetikon ve otilonyumun farmasötik kombinasyonları.
EP2481403A1 (en)	2011-02-01	2012-08-01	Deva Holding Anonim Sirketi	Pharmaceutical combination of otilonium and trimebutine
EP2481395A1 (en)	2011-02-01	2012-08-01	Deva Holding Anonim Sirketi	Sachet, effervescent tablet and dry syrup of otilonium
EP3294269A1 (en)	2015-06-12	2018-03-21	Santa Farma Ilaç Sanayi A.S.	Oral pharmaceutical composition comprising otilonium bromide and simethicone with certain bulk density and improved dissolution characteristics

1986
- 1986-11-04 IT IT8609514A patent/IT1216283B/it active
1987
- 1987-10-27 CA CA000550314A patent/CA1311419C/en not_active Expired - Lifetime
- 1987-11-03 AT AT87830386T patent/ATE94388T1/de active
- 1987-11-03 ES ES87830386T patent/ES2058138T3/es not_active Expired - Lifetime
- 1987-11-03 EP EP87830386A patent/EP0270503B1/en not_active Expired - Lifetime
- 1987-11-03 DE DE87830386T patent/DE3787448T2/de not_active Expired - Fee Related
- 1987-11-04 US US07/117,751 patent/US4978772A/en not_active Expired - Fee Related
- 1987-11-04 JP JP62277534A patent/JP2514670B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IT8609514A0 (it)	1986-11-04
JP2514670B2 (ja)	1996-07-10
CA1311419C (en)	1992-12-15
JPS63130530A (ja)	1988-06-02
EP0270503B1 (en)	1993-09-15
DE3787448T2 (de)	1994-01-13
DE3787448D1 (de)	1993-10-21
EP0270503A3 (en)	1990-04-18
EP0270503A2 (en)	1988-06-08
ATE94388T1 (de)	1993-10-15
US4978772A (en)	1990-12-18
ES2058138T3 (es)	1994-11-01

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Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19981127