ATE97404T1 - Prostazyklin-(pgi2)-analoge. - Google Patents

Prostazyklin-(pgi2)-analoge.

Info

Publication number: ATE97404T1
Authority: AT; Austria
Prior art keywords: pgi2; analogues; hydrogen; straight; alkyl
Prior art date: 1986-03-31

Application number

AT87104669T

Other languages

English (en)

Inventor

Sachio Mori

Hikozo Iwakura

Shozo Takechi

Original Assignee

Shionogi & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-03-31

Filing date

1987-03-30

Publication date

1993-12-15

1987-03-30 Application filed by Shionogi & Co filed Critical Shionogi & Co

1993-12-15 Application granted granted Critical

1993-12-15 Publication of ATE97404T1 publication Critical patent/ATE97404T1/de

Links

KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 title abstract 2
150000003174 prostaglandin I2 derivatives Chemical class 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 3
125000000304 alkynyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000002785 anti-thrombosis Effects 0.000 abstract 1
239000003146 anticoagulant agent Substances 0.000 abstract 1
239000003699 antiulcer agent Substances 0.000 abstract 1
-1 arythio Chemical group 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229960001123 epoprostenol Drugs 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Hematology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Paper (AREA)
Vending Machines For Individual Products (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT87104669T 1986-03-31 1987-03-30 Prostazyklin-(pgi2)-analoge. ATE97404T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP7493286		1986-03-31
EP87104669A EP0240890B1 (de)	1986-03-31	1987-03-30	Prostazyklin-(PGI2)-Analoge

Publications (1)

Publication Number	Publication Date
ATE97404T1 true ATE97404T1 (de)	1993-12-15

Family

ID=13561619

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT87104669T ATE97404T1 (de)	1986-03-31	1987-03-30	Prostazyklin-(pgi2)-analoge.

Country Status (7)

Country	Link
US (2)	US4820836A (de)
EP (1)	EP0240890B1 (de)
JP (1)	JPH07121907B2 (de)
AT (1)	ATE97404T1 (de)
CA (1)	CA1284642C (de)
DE (2)	DE240890T1 (de)
ES (1)	ES2008067T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU227157B1 (en) *	2001-07-30	2010-09-28	Chinoin Gyogyszer Es Vegyeszet	Production of beraprost ester by selective oxidation
US20070243632A1 (en) *	2003-07-08	2007-10-18	Coller Barry S	Methods for measuring platelet reactivity of patients that have received drug eluting stents
US7790362B2 (en) *	2003-07-08	2010-09-07	Accumetrics, Inc.	Controlled platelet activation to monitor therapy of ADP antagonists
US7595169B2 (en) *	2005-04-27	2009-09-29	Accumetrics, Inc.	Method for determining percent platelet aggregation
CN101675342A (zh) *	2007-05-03	2010-03-17	阿库米特里克斯股份有限公司	测量凝血酶受体拮抗剂对血小板聚集的抑制的方法
TWI392673B (zh)	2008-08-27	2013-04-11	Calcimedica Inc	調控細胞內鈣離子濃度之化合物
US8524763B2 (en)	2008-09-22	2013-09-03	Calcimedica, Inc.	Inhibitors of store operated calcium release

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3006865A1 (de) *	1980-02-23	1981-09-10	Hoechst Ag, 6000 Frankfurt	Hetero-imino-prostacycline
US4496742A (en) *	1981-10-13	1985-01-29	The Upjohn Company	Analogs of 5,6-dihydro PGI2
US4588823A (en) *	1982-02-16	1986-05-13	The Upjohn Company	9-substituted carbacyclin analogs
US4487960A (en) *	1982-04-19	1984-12-11	The Upjohn Company	9-Substituted carbacyclin analogs

1987
- 1987-03-11 CA CA000531708A patent/CA1284642C/en not_active Expired - Fee Related
- 1987-03-13 US US07/025,807 patent/US4820836A/en not_active Expired - Fee Related
- 1987-03-20 JP JP62066817A patent/JPH07121907B2/ja not_active Expired - Fee Related
- 1987-03-30 DE DE198787104669T patent/DE240890T1/de active Pending
- 1987-03-30 DE DE87104669T patent/DE3788149T2/de not_active Expired - Fee Related
- 1987-03-30 ES ES87104669T patent/ES2008067T3/es not_active Expired - Lifetime
- 1987-03-30 AT AT87104669T patent/ATE97404T1/de not_active IP Right Cessation
- 1987-03-30 EP EP87104669A patent/EP0240890B1/de not_active Expired - Lifetime
1988
- 1988-08-01 US US07/226,844 patent/US4855449A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0240890A2 (de)	1987-10-14
DE3788149T2 (de)	1994-04-07
CA1284642C (en)	1991-06-04
US4855449A (en)	1989-08-08
ES2008067A4 (es)	1989-07-16
JPH07121907B2 (ja)	1995-12-25
EP0240890B1 (de)	1993-11-18
DE240890T1 (de)	1988-04-28
US4820836A (en)	1989-04-11
ES2008067T3 (es)	1994-11-16
DE3788149D1 (de)	1993-12-23
EP0240890A3 (en)	1989-05-10
JPS6366168A (ja)	1988-03-24

Legal Events

Date	Code	Title	Description
1994-07-15	UEP	Publication of translation of european patent specification
1997-12-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
YU47099B (sh)	1994-12-28	Postupak za dobijanje makrolidnih jedinjenja
FI842987A0 (fi)	1984-07-26	Nya 1,8-naftyridin-derivat och foerfaranden foer deras framstaellning.
ATE68473T1 (de)	1991-11-15	1-phenyl-3-naphthalenyloxy-propanamine.
DE3665711D1 (de)	1989-10-26	Novel guanidinomethylbenzoic acid derivatives
IE860222L (en)	1986-07-28	Imidazole derivatives.
EP0392560A3 (de)	1992-01-08	Diaminoethylen-Verbindungen
GR3003776T3 (de)	1993-03-16
ES2046229T3 (es)	1994-02-01	Composicion antiulcerosa.
ATE97404T1 (de)	1993-12-15	Prostazyklin-(pgi2)-analoge.
KR860700250A (ko)	1986-08-01	신규 아미딘 화합물
DE3864707D1 (de)	1991-10-17	Benzoxazin-derivate und verfahren zu ihrer herstellung.
ATE73768T1 (de)	1992-04-15	2,5,6,7-tetranor-18,18,19,19-tetradehydro-4,8inter-m-phenylene-pgi2-derivate.
ATE105565T1 (de)	1994-05-15	Pradimicinderivate.
ATE94548T1 (de)	1993-10-15	Prostaglandin-vorlaeufer und ihre herstellung.
AU6101890A (en)	1991-02-21	Therapeutic agents for the treatment of peptic ulcer disease
EP0367671A3 (de)	1991-07-31	Beta-D-phenylthioxyloside, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP0143440A3 (de)	1985-07-17	Insektizide Zusammensetzung
DE69204766D1 (de)	1995-10-19	Verfahren zur Herstellung von Bicyclo(3.2.0)hept-2-en-7-onen.
IE42048L (en)	1976-02-15	Dienylphosphates and 1, 4-cycloadducts.
ES2045335T3 (es)	1994-01-16	Un procedimiento para la preparacion de nuevas s-difluorometilhomocisteinas.
FR2550189B1 (fr)	1986-03-28	Nouveaux derives acetyleniques possedant une activite d'inhibiteurs d'enzyme, leur preparation et leur application comme medicament
KR830001960A (ko)	1983-05-21	2-아자에리스리난유도체의 제조방법