ATE97895T1 - Cannabinol-derivate und immuntest. - Google Patents

Cannabinol-derivate und immuntest.

Info

Publication number: ATE97895T1
Authority: AT; Austria
Prior art keywords: derivative; group; cannabinol; aminoalkyl group; derivatives
Prior art date: 1987-01-27

Application number

AT88100732T

Other languages

English (en)

Inventor

Alan Joseph Mcnally

Alan Schwartz

Magdalena Usategui

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-01-27

Filing date

1988-01-20

Publication date

1993-12-15

1988-01-20 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1993-12-15 Application granted granted Critical

1993-12-15 Publication of ATE97895T1 publication Critical patent/ATE97895T1/de

Links

VBGLYOIFKLUMQG-UHFFFAOYSA-N Cannabinol Chemical class C1=C(C)C=C2C3=C(O)C=C(CCCCC)C=C3OC(C)(C)C2=C1 VBGLYOIFKLUMQG-UHFFFAOYSA-N 0.000 title abstract 4
PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical group NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 abstract 3
125000004103 aminoalkyl group Chemical group 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
238000001514 detection method Methods 0.000 abstract 1
238000003018 immunoassay Methods 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
239000012948 isocyanate Substances 0.000 abstract 1
150000002513 isocyanates Chemical class 0.000 abstract 1
150000002540 isothiocyanates Chemical class 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
210000002700 urine Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Analytical Chemistry (AREA)
Cell Biology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Anesthesiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AT88100732T 1987-01-27 1988-01-20 Cannabinol-derivate und immuntest. ATE97895T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/007,838 US4833073A (en)	1987-01-27	1987-01-27	Immunoassay for tetrahydrocannabinol metabolites
EP88100732A EP0276732B1 (de)	1987-01-27	1988-01-20	Cannabinol-Derivate und Immuntest

Publications (1)

Publication Number	Publication Date
ATE97895T1 true ATE97895T1 (de)	1993-12-15

Family

ID=21728380

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88100732T ATE97895T1 (de)	1987-01-27	1988-01-20	Cannabinol-derivate und immuntest.

Country Status (12)

Country	Link
US (1)	US4833073A (de)
EP (1)	EP0276732B1 (de)
JP (1)	JPH0819117B2 (de)
AT (1)	ATE97895T1 (de)
AU (1)	AU614733B2 (de)
DE (1)	DE3885911T2 (de)
DK (1)	DK37888A (de)
ES (1)	ES2060610T3 (de)
FI (1)	FI96685C (de)
HK (1)	HK63595A (de)
NO (1)	NO171274C (de)
NZ (1)	NZ223289A (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5264373A (en) *	1987-02-17	1993-11-23	Abbott Laboratories	Fluorescence polarization immunoassay for tetrahydrocannabinoids
EP0392332A3 (de) *	1989-04-12	1992-01-08	F. Hoffmann-La Roche Ag	Fluoreszenzpolarisationsimmunoassay und Reagentien dafür
US5001743A (en) *	1990-01-10	1991-03-19	Northern Telecom Limited	Method and apparatus for controlling a telephone answering device
IL99468A (en) *	1991-09-12	1997-09-30	Yissum Res Dev Co	(3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them
US5460944A (en) *	1991-10-28	1995-10-24	Boehringer Mannheim Gmbh	Storable protein solution
US5292899A (en) *	1991-11-27	1994-03-08	Synthetic Technology Corporation	Synthesis of 11-nor-Δ-9-tetrahydrocannabinol-9-carboxylic acid glucuronide
US5237057A (en) *	1992-04-06	1993-08-17	Biosite Diagnostics, Inc.	Tetrahydrocannabinol derivatives and protein and polypeptide tetrahydrocannabinol derivative conjugates and labels
US5315015A (en) *	1992-11-10	1994-05-24	Hoffmann-La Roche Inc.	Compounds having improved fluorescence in fluorescence polarization immunoassays and immunoassays utilizing same
US5817766A (en) *	1995-04-05	1998-10-06	Roche Diagnostic Systems, Inc.	Reagents for a cannabinoid immunoassay
US6162829A (en) *	1997-10-17	2000-12-19	Atlantic Pharmaceuticals, Inc.	(3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics
CA2340444A1 (en) *	1998-05-04	1999-11-11	The University Of Connecticut	Cannabinoids selective for the cb2 receptor
US7589220B2 (en)	1998-06-09	2009-09-15	University Of Connecticut	Inhibitors of the anandamide transporter
US7897598B2 (en)	1998-06-09	2011-03-01	Alexandros Makriyannis	Inhibitors of the anandamide transporter
US6248598B1 (en)	1998-09-17	2001-06-19	Stuart C. Bogema	Immunoassay that provides for both collection of saliva and assay of saliva for one or more analytes with visual readout
US7276613B1 (en)	1998-11-24	2007-10-02	University Of Connecticut	Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en)	1998-11-24	2007-01-09	University Of Connecticut	Cannabimimetic lipid amides as useful medications
US6566560B2 (en)	1999-03-22	2003-05-20	Immugen Pharmaceuticals, Inc.	Resorcinolic compounds
CN1377261A (zh)	1999-03-22	2002-10-30	免疫力药品有限公司	治疗免疫疾病
US6943266B1 (en)	1999-10-18	2005-09-13	University Of Connecticut	Bicyclic cannabinoid agonists for the cannabinoid receptor
US6900236B1 (en)	1999-10-18	2005-05-31	University Of Connecticut	Cannabimimetic indole derivatives
US7741365B2 (en)	1999-10-18	2010-06-22	University Of Connecticut	Peripheral cannabinoid receptor (CB2) selective ligands
US7393842B2 (en)	2001-08-31	2008-07-01	University Of Connecticut	Pyrazole analogs acting on cannabinoid receptors
WO2001028329A1 (en)	1999-10-18	2001-04-26	University Of Connecticut	Peripheral cannabinoid receptor (cb2) selective ligands
US8084467B2 (en)	1999-10-18	2011-12-27	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
US7119108B1 (en)	1999-10-18	2006-10-10	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
US6541510B2 (en) *	2000-09-28	2003-04-01	Immugen Pharmaceuticals, Inc.	Antiviral methods and compounds
AU2001296402A1 (en) *	2000-09-28	2002-04-08	Immugen Pharmaceuticals, Inc.	Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
US7329651B2 (en)	2001-01-26	2008-02-12	University Of Connecticut	Cannabimimetic ligands
WO2002060447A1 (en)	2001-01-29	2002-08-08	University Of Connecticut	Receptor selective cannabimimetic aminoalkylindoles
WO2003005960A2 (en)	2001-07-13	2003-01-23	University Of Connecticut	Novel bicyclic and tricyclic cannabinoids
WO2003035005A2 (en)	2001-10-26	2003-05-01	University Of Connecticut	Heteroindanes: a new class of potent cannabimimetic ligands
WO2003080043A1 (en) *	2002-03-18	2003-10-02	Immugen Pharmaceuticals, Inc.	Topical formulations of resorcinols and cannibinoids and methods of use
AU2003265663A1 (en) *	2002-08-23	2004-03-11	University Of Connecticut	Keto cannabinoids with therapeutic indications
US7195882B2 (en) *	2003-06-03	2007-03-27	Roche Diagnostics Operations, Inc.	Monoclonal antibodies specific for buprenorphine and metabolites thereof
WO2005026178A2 (en)	2003-07-01	2005-03-24	Roche Diagnostics Gmbh	Electrochemical affinity biosensor system and methods
US20060051824A1 (en) *	2004-09-03	2006-03-09	Haoyun An	Tetrahydrocannabinoid antigens and method of use
GB0725234D0 (en) *	2007-12-24	2008-02-06	Oxtex Ltd	Electrochemical assays
US10408786B2 (en)	2012-06-14	2019-09-10	ChemiSensor, LLP	Distributable chemical sampling and sensing system
US10254298B1 (en) *	2015-03-25	2019-04-09	National Technology & Engineering Solutions Of Sandia, Llc	Detection of metabolites for controlled substances
US10458963B2 (en)	2016-06-08	2019-10-29	Kathleen Stitzlein	Quantitative HPTLC cannabinoid field testing device and method
US10981174B1 (en)	2016-08-04	2021-04-20	National Technology & Engineering Solutions Of Sandia, Llc	Protein and nucleic acid detection for microfluidic devices
US12545694B2 (en)	2020-01-08	2026-02-10	Chengdu Baiyu Pharmaceutical Co., Ltd.	Cannabidiol derivatives, preparation method thereof and use thereof
CN113087743B (zh) *	2020-01-08	2023-04-28	成都百裕制药股份有限公司	四氢大麻酚衍生物及其制备方法和在医药上的应用
CN119534358A (zh) *	2023-08-28	2025-02-28	广州达安基因股份有限公司	Δ9-四氢大麻酚的检测试剂及其制备方法和检测方法

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US3649650A (en) *	1970-02-13	1972-03-14	Little Inc A	Novel derivatives of tetrahydro-cannabinol
IL39323A (en) *	1971-05-14	1975-08-31	Syva Co	Highly sensitive assay method employing an enzyme for amplification
US4438207A (en) *	1979-09-26	1984-03-20	Hoffmann-La Roche Inc.	Radioimmunoassay for cannabinoids
US4378428A (en) *	1981-03-30	1983-03-29	Baker Instruments Corporation	Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays
US4652681A (en) *	1982-04-15	1987-03-24	Drug Science Foundation	Aminoalkoxy derivatives of propranolol for immunoassay applications
US4650771A (en) *	1983-11-04	1987-03-17	Miles Laboratories, Inc.	Immunogens, antibodies, labeled conjugates, and related derivatives for lidocaine and analogs thereof

1987
- 1987-01-27 US US07/007,838 patent/US4833073A/en not_active Expired - Lifetime
1988
- 1988-01-20 DE DE88100732T patent/DE3885911T2/de not_active Expired - Lifetime
- 1988-01-20 ES ES88100732T patent/ES2060610T3/es not_active Expired - Lifetime
- 1988-01-20 AT AT88100732T patent/ATE97895T1/de not_active IP Right Cessation
- 1988-01-20 EP EP88100732A patent/EP0276732B1/de not_active Expired - Lifetime
- 1988-01-25 JP JP63012742A patent/JPH0819117B2/ja not_active Expired - Fee Related
- 1988-01-26 NO NO880330A patent/NO171274C/no unknown
- 1988-01-26 DK DK037888A patent/DK37888A/da not_active Application Discontinuation
- 1988-01-26 FI FI880332A patent/FI96685C/fi not_active IP Right Cessation
- 1988-01-26 NZ NZ223289A patent/NZ223289A/xx unknown
- 1988-01-27 AU AU11115/88A patent/AU614733B2/en not_active Ceased
1995
- 1995-04-27 HK HK63595A patent/HK63595A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU1111588A (en)	1988-07-28
JPS63192770A (ja)	1988-08-10
FI880332A7 (fi)	1988-07-28
FI96685B (fi)	1996-04-30
HK63595A (en)	1995-05-05
DE3885911T2 (de)	1994-03-24
NZ223289A (en)	1989-06-28
NO880330D0 (no)	1988-01-26
FI880332A0 (fi)	1988-01-26
FI96685C (fi)	1996-08-12
DK37888A (da)	1988-07-28
NO171274C (no)	1993-02-17
US4833073A (en)	1989-05-23
JPH0819117B2 (ja)	1996-02-28
EP0276732A2 (de)	1988-08-03
EP0276732A3 (en)	1989-02-22
AU614733B2 (en)	1991-09-12
DE3885911D1 (de)	1994-01-13
ES2060610T3 (es)	1994-12-01
NO880330L (no)	1988-07-28
NO171274B (no)	1992-11-09
DK37888D0 (da)	1988-01-26
EP0276732B1 (de)	1993-12-01

Legal Events

Date	Code	Title	Description
1994-10-15	UEP	Publication of translation of european patent specification
1997-10-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
NO880330L (no)	1988-07-28	Cannabinolderivater.
DE3880383D1 (de)	1993-05-27	Vernetzungsmittel zur haarbehandlung.
KR910007935A (ko)	1991-05-30	세고리형 카르바페넴 화합물
DE3867572D1 (de)	1992-02-20	Benzothiazol-derivat und es als aktiven bestandteil enthaltendes antirheumatisches mittel.
ATE74132T1 (de)	1992-04-15	Imid-derivate, ihre herstellung und ihre verwendung.
PT86785A (pt)	1988-03-01	Novel naphthalene derivatives having use as antiallergy and antiinflammatory agents
ATE227710T1 (de)	2002-11-15	Oxazole derivate,ihre herstellung und verwendung
ATE92489T1 (de)	1993-08-15	Imid-derivate, ihre herstellung und verwendung.
ATE72831T1 (de)	1992-03-15	Konjugate von glucose-6-phosphat-dehydrogenase, ihre herstellung und verwendung.
KR890009962A (ko)	1989-08-05	매뉴마이신 유도체, 이의 제조방법 및 용도
ES2046229T3 (es)	1994-02-01	Composicion antiulcerosa.
ES2065994T3 (es)	1995-03-01	Beta-dicetonas substituidas.
DE3675778D1 (de)	1991-01-03	(2-amino-4-aryl-thiazol-5-yl)aethanol, und deren derivate mit diuretischer aktivitaet und verfahren zu deren herstellung.
DK396989A (da)	1990-02-14	Cycliske svovlforbindelser
ATE38675T1 (de)	1988-12-15	Phosphatesterderivate und ihre verwendung als anti-krebsmittel.
DK21287A (da)	1987-07-18	Penemderivater
SE8506015D0 (sv)	1985-12-19	Novel 16,17-acetalsubstituted pregnane 21-oic acid derivatives
ATE60328T1 (de)	1991-02-15	Derivate vom benzoquinonylphenylalkansaeure-amid.
DE3677857D1 (de)	1991-04-11	2,5-dimethylpyrrolderivative, ihre herstellung und ihre verwendung.
EP0349274A3 (en)	1990-03-21	Photographic dot enhancing compositions and methods for their use
ES2041790T3 (es)	1993-12-01	Derivados de tetrahidroisoquinolina amino-substituidos y su procedimiento de obtencion.
KR890008151A (ko)	1989-07-10	키놀린 카르복산의 유도체
DK0563797T3 (da)	2000-09-18	Pyridiniumderivater
ES2018874B3 (es)	1991-05-16	Derivado taurine, su preparacion y composiciones farmaceuticas que lo contiene
ATE60048T1 (de)	1991-02-15	Aminoverbindungen und diese enthaltende fungizide.