NO171274C - Tetrahydrocannabinolderivater samt anvendelse derav ved immunoassay for paavisning av cannabinol-metabolitter - Google Patents

Tetrahydrocannabinolderivater samt anvendelse derav ved immunoassay for paavisning av cannabinol-metabolitter

Info

Publication number: NO171274C
Authority: NO; Norway
Prior art keywords: derivative; cannabinol; group; immunoassay; derivatives
Prior art date: 1987-01-27

Application number

NO880330A

Other languages

English (en)

Norwegian (no)

Other versions

NO880330D0 (no

NO171274B (no

NO880330L (no

Inventor

Alan Joseph Mcnally

Alan Schwartz

Magdalena Usategui

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-01-27

Filing date

1988-01-26

Publication date

1993-02-17

1988-01-26 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1988-01-26 Publication of NO880330D0 publication Critical patent/NO880330D0/no

1988-07-28 Publication of NO880330L publication Critical patent/NO880330L/no

1992-11-09 Publication of NO171274B publication Critical patent/NO171274B/no

1993-02-17 Publication of NO171274C publication Critical patent/NO171274C/no

Links

VBGLYOIFKLUMQG-UHFFFAOYSA-N Cannabinol Chemical class C1=C(C)C=C2C3=C(O)C=C(CCCCC)C=C3OC(C)(C)C2=C1 VBGLYOIFKLUMQG-UHFFFAOYSA-N 0.000 title abstract 4
238000003018 immunoassay Methods 0.000 title abstract 2
CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical class C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 title 1
PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical group NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 abstract 3
125000004103 aminoalkyl group Chemical group 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
238000001514 detection method Methods 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
239000012948 isocyanate Substances 0.000 abstract 1
150000002513 isocyanates Chemical class 0.000 abstract 1
150000002540 isothiocyanates Chemical class 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
210000002700 urine Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Analytical Chemistry (AREA)
Cell Biology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Anesthesiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO880330A 1987-01-27 1988-01-26 Tetrahydrocannabinolderivater samt anvendelse derav ved immunoassay for paavisning av cannabinol-metabolitter NO171274C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/007,838 US4833073A (en)	1987-01-27	1987-01-27	Immunoassay for tetrahydrocannabinol metabolites

Publications (4)

Publication Number	Publication Date
NO880330D0 NO880330D0 (no)	1988-01-26
NO880330L NO880330L (no)	1988-07-28
NO171274B NO171274B (no)	1992-11-09
NO171274C true NO171274C (no)	1993-02-17

Family

ID=21728380

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO880330A NO171274C (no)	1987-01-27	1988-01-26	Tetrahydrocannabinolderivater samt anvendelse derav ved immunoassay for paavisning av cannabinol-metabolitter

Country Status (12)

Country	Link
US (1)	US4833073A (de)
EP (1)	EP0276732B1 (de)
JP (1)	JPH0819117B2 (de)
AT (1)	ATE97895T1 (de)
AU (1)	AU614733B2 (de)
DE (1)	DE3885911T2 (de)
DK (1)	DK37888A (de)
ES (1)	ES2060610T3 (de)
FI (1)	FI96685C (de)
HK (1)	HK63595A (de)
NO (1)	NO171274C (de)
NZ (1)	NZ223289A (de)

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US5264373A (en) *	1987-02-17	1993-11-23	Abbott Laboratories	Fluorescence polarization immunoassay for tetrahydrocannabinoids
EP0392332A3 (de) *	1989-04-12	1992-01-08	F. Hoffmann-La Roche Ag	Fluoreszenzpolarisationsimmunoassay und Reagentien dafür
US5001743A (en) *	1990-01-10	1991-03-19	Northern Telecom Limited	Method and apparatus for controlling a telephone answering device
IL99468A (en) *	1991-09-12	1997-09-30	Yissum Res Dev Co	(3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them
US5460944A (en) *	1991-10-28	1995-10-24	Boehringer Mannheim Gmbh	Storable protein solution
US5292899A (en) *	1991-11-27	1994-03-08	Synthetic Technology Corporation	Synthesis of 11-nor-Δ-9-tetrahydrocannabinol-9-carboxylic acid glucuronide
US5237057A (en) *	1992-04-06	1993-08-17	Biosite Diagnostics, Inc.	Tetrahydrocannabinol derivatives and protein and polypeptide tetrahydrocannabinol derivative conjugates and labels
US5315015A (en) *	1992-11-10	1994-05-24	Hoffmann-La Roche Inc.	Compounds having improved fluorescence in fluorescence polarization immunoassays and immunoassays utilizing same
US5817766A (en) *	1995-04-05	1998-10-06	Roche Diagnostic Systems, Inc.	Reagents for a cannabinoid immunoassay
US6162829A (en) *	1997-10-17	2000-12-19	Atlantic Pharmaceuticals, Inc.	(3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics
US6166066A (en) *	1998-05-04	2000-12-26	The University Of Connecticut	Cannabinoids selective for the CB2 receptor
US7897598B2 (en)	1998-06-09	2011-03-01	Alexandros Makriyannis	Inhibitors of the anandamide transporter
US7589220B2 (en)	1998-06-09	2009-09-15	University Of Connecticut	Inhibitors of the anandamide transporter
US6248598B1 (en)	1998-09-17	2001-06-19	Stuart C. Bogema	Immunoassay that provides for both collection of saliva and assay of saliva for one or more analytes with visual readout
US7276613B1 (en)	1998-11-24	2007-10-02	University Of Connecticut	Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en)	1998-11-24	2007-01-09	University Of Connecticut	Cannabimimetic lipid amides as useful medications
BR0009200A (pt)	1999-03-22	2001-12-26	Immugen Pharmaceuticals Inc	Compostos e composições para o tratamento dedoenças associada com disfunção imune
US6566560B2 (en)	1999-03-22	2003-05-20	Immugen Pharmaceuticals, Inc.	Resorcinolic compounds
US7119108B1 (en)	1999-10-18	2006-10-10	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
US7741365B2 (en)	1999-10-18	2010-06-22	University Of Connecticut	Peripheral cannabinoid receptor (CB2) selective ligands
US8084467B2 (en)	1999-10-18	2011-12-27	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
US6900236B1 (en)	1999-10-18	2005-05-31	University Of Connecticut	Cannabimimetic indole derivatives
US6943266B1 (en)	1999-10-18	2005-09-13	University Of Connecticut	Bicyclic cannabinoid agonists for the cannabinoid receptor
US7393842B2 (en)	2001-08-31	2008-07-01	University Of Connecticut	Pyrazole analogs acting on cannabinoid receptors
DE60033834T2 (de)	1999-10-18	2007-11-15	The University Of Connecticut, Farmington	Für periphäre cannabinoid-rezeptoren selektive liganden
AU2002213429A1 (en) *	2000-09-28	2002-04-08	Immugen Pharmaceuticals, Inc.	Antiviral methods and compounds
US20020137802A1 (en) *	2000-09-28	2002-09-26	Travis Craig R.	Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
JP2004532185A (ja)	2001-01-26	2004-10-21	ユニバーシティオブコネチカット	新規なカンナビミメティックリガンド
EP1363632B1 (de)	2001-01-29	2010-08-25	The University of Connecticut	Rezeptor-selektive cannabimimetische aminoalkylindole
WO2003005960A2 (en)	2001-07-13	2003-01-23	University Of Connecticut	Novel bicyclic and tricyclic cannabinoids
CN1589269A (zh)	2001-10-26	2005-03-02	康涅狄格大学	杂1,2－二氢化茚:一类新型有效的大麻配体
WO2003080043A1 (en) *	2002-03-18	2003-10-02	Immugen Pharmaceuticals, Inc.	Topical formulations of resorcinols and cannibinoids and methods of use
CA2496097A1 (en) *	2002-08-23	2004-03-04	University Of Connecticut	Keto cannabinoids with therapeutic indications
US7195882B2 (en) *	2003-06-03	2007-03-27	Roche Diagnostics Operations, Inc.	Monoclonal antibodies specific for buprenorphine and metabolites thereof
CA2530211C (en)	2003-07-01	2011-10-04	Eric R. Diebold	Electrochemical affinity biosensor system and methods
US20060051824A1 (en) *	2004-09-03	2006-03-09	Haoyun An	Tetrahydrocannabinoid antigens and method of use
GB0725234D0 (en) *	2007-12-24	2008-02-06	Oxtex Ltd	Electrochemical assays
US10408786B2 (en)	2012-06-14	2019-09-10	ChemiSensor, LLP	Distributable chemical sampling and sensing system
US10254298B1 (en)	2015-03-25	2019-04-09	National Technology & Engineering Solutions Of Sandia, Llc	Detection of metabolites for controlled substances
US10458963B2 (en)	2016-06-08	2019-10-29	Kathleen Stitzlein	Quantitative HPTLC cannabinoid field testing device and method
US10981174B1 (en)	2016-08-04	2021-04-20	National Technology & Engineering Solutions Of Sandia, Llc	Protein and nucleic acid detection for microfluidic devices
US12545694B2 (en)	2020-01-08	2026-02-10	Chengdu Baiyu Pharmaceutical Co., Ltd.	Cannabidiol derivatives, preparation method thereof and use thereof
CN113087743B (zh) *	2020-01-08	2023-04-28	成都百裕制药股份有限公司	四氢大麻酚衍生物及其制备方法和在医药上的应用
CN119534358A (zh) *	2023-08-28	2025-02-28	广州达安基因股份有限公司	Δ9-四氢大麻酚的检测试剂及其制备方法和检测方法

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US3649650A (en) *	1970-02-13	1972-03-14	Little Inc A	Novel derivatives of tetrahydro-cannabinol
IL39323A (en) *	1971-05-14	1975-08-31	Syva Co	Highly sensitive assay method employing an enzyme for amplification
US4438207A (en) *	1979-09-26	1984-03-20	Hoffmann-La Roche Inc.	Radioimmunoassay for cannabinoids
US4378428A (en) *	1981-03-30	1983-03-29	Baker Instruments Corporation	Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays
US4652681A (en) *	1982-04-15	1987-03-24	Drug Science Foundation	Aminoalkoxy derivatives of propranolol for immunoassay applications
US4650771A (en) *	1983-11-04	1987-03-17	Miles Laboratories, Inc.	Immunogens, antibodies, labeled conjugates, and related derivatives for lidocaine and analogs thereof

1987
- 1987-01-27 US US07/007,838 patent/US4833073A/en not_active Expired - Lifetime
1988
- 1988-01-20 AT AT88100732T patent/ATE97895T1/de not_active IP Right Cessation
- 1988-01-20 EP EP88100732A patent/EP0276732B1/de not_active Expired - Lifetime
- 1988-01-20 ES ES88100732T patent/ES2060610T3/es not_active Expired - Lifetime
- 1988-01-20 DE DE88100732T patent/DE3885911T2/de not_active Expired - Lifetime
- 1988-01-25 JP JP63012742A patent/JPH0819117B2/ja not_active Expired - Fee Related
- 1988-01-26 NO NO880330A patent/NO171274C/no unknown
- 1988-01-26 DK DK037888A patent/DK37888A/da not_active Application Discontinuation
- 1988-01-26 NZ NZ223289A patent/NZ223289A/xx unknown
- 1988-01-26 FI FI880332A patent/FI96685C/fi not_active IP Right Cessation
- 1988-01-27 AU AU11115/88A patent/AU614733B2/en not_active Ceased
1995
- 1995-04-27 HK HK63595A patent/HK63595A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2060610T3 (es)	1994-12-01
NO880330D0 (no)	1988-01-26
NZ223289A (en)	1989-06-28
DE3885911D1 (de)	1994-01-13
AU1111588A (en)	1988-07-28
ATE97895T1 (de)	1993-12-15
FI96685C (fi)	1996-08-12
JPH0819117B2 (ja)	1996-02-28
NO171274B (no)	1992-11-09
FI96685B (fi)	1996-04-30
AU614733B2 (en)	1991-09-12
EP0276732A2 (de)	1988-08-03
DK37888D0 (da)	1988-01-26
EP0276732B1 (de)	1993-12-01
DK37888A (da)	1988-07-28
FI880332A7 (fi)	1988-07-28
DE3885911T2 (de)	1994-03-24
HK63595A (en)	1995-05-05
US4833073A (en)	1989-05-23
NO880330L (no)	1988-07-28
FI880332A0 (fi)	1988-01-26
JPS63192770A (ja)	1988-08-10
EP0276732A3 (en)	1989-02-22

Publication	Publication Date	Title
NO171274C (no)	1993-02-17	Tetrahydrocannabinolderivater samt anvendelse derav ved immunoassay for paavisning av cannabinol-metabolitter
KR890003720A (ko)	1989-04-17	벤조티아졸 및 그를 유효성분으로 함유하는 항류머티스제
ATE88338T1 (de)	1993-05-15	Vernetzungsmittel zur haarbehandlung.
DE69609108D1 (de)	2000-08-10	Verbesserte Immunoessayreagenzien zum Nachweis von Kannabinoiden
ES2182054T3 (es)	2003-03-01	Derivados de oxazol, su produccion y uso.
NO890689L (no)	1989-08-21	Spesielle kjemiluminiscerende akridinderivater og deres anvendelse i luminiscens-immunoanalyser.
ATE72831T1 (de)	1992-03-15	Konjugate von glucose-6-phosphat-dehydrogenase, ihre herstellung und verwendung.
KR890009962A (ko)	1989-08-05	매뉴마이신 유도체, 이의 제조방법 및 용도
DK37691A (da)	1991-03-01	Substituerede beta-diketoner, farmaceutiske midler indeholdende disse forbindelser samt anvendelse deraf
ES2157292T3 (es)	2001-08-16	Inhibidores 6-azaindol de la tromboxano sintasa.
KR890008110A (ko)	1989-07-08	피리미딘 유도체
KR830006281A (ko)	1983-09-20	비스글리코시일 모라노린 유도체의 제조법
ES2136346T3 (es)	1999-11-16	Procedimiento para la determinacion cuantitativa de peroxidos, una substancia que reacciona con peroxido, o un derivado de pirazolopiridopiridazina.
KR900003142A (ko)	1990-03-23	환형 황을 함유하는 화합물
ATE38675T1 (de)	1988-12-15	Phosphatesterderivate und ihre verwendung als anti-krebsmittel.
ES2058532T3 (es)	1994-11-01	Composiciones intensificadoras de puntos para sistemas fotograficos y metodos para su uso.
DK21287D0 (da)	1987-01-15	Hidtil ukdendte forbindelser og fremgangsmaader
SE8506015D0 (sv)	1985-12-19	Novel 16,17-acetalsubstituted pregnane 21-oic acid derivatives
KR890008151A (ko)	1989-07-10	키놀린 카르복산의 유도체
DK0381628T3 (da)	1995-05-01	Glycocyamidinderivater
KR890002190A (ko)	1989-04-08	퀴놀린 카르본산 유도체
PH22355A (en)	1988-08-12	4-(substituted alkyl)-n-(1,3-dithiolan-2-ylidene) aniline
KR890001956A (ko)	1989-04-06	안식향산 유도체
KR890016032A (ko)	1989-11-28	푸란 유도체의 제조방법
PT88464A (pt)	1988-10-01	Process for the preparation of a macrolide compound