ATE99679T1 - 3,5-dichloro-2,4-dimethoxy-6(trichlormethyl)pyridine. - Google Patents
3,5-dichloro-2,4-dimethoxy-6(trichlormethyl)pyridine.Info
- Publication number
- ATE99679T1 ATE99679T1 AT87112757T AT87112757T ATE99679T1 AT E99679 T1 ATE99679 T1 AT E99679T1 AT 87112757 T AT87112757 T AT 87112757T AT 87112757 T AT87112757 T AT 87112757T AT E99679 T1 ATE99679 T1 AT E99679T1
- Authority
- AT
- Austria
- Prior art keywords
- trichloromethyl
- pyridine
- dimethoxy
- dichloro
- tetrachloro
- Prior art date
Links
- DZVPGIORVGSQMC-UHFFFAOYSA-N 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)pyridine Chemical compound COC1=NC(C(Cl)(Cl)Cl)=C(Cl)C(OC)=C1Cl DZVPGIORVGSQMC-UHFFFAOYSA-N 0.000 title abstract 2
- YMBFWRZKTZICHS-UHFFFAOYSA-N 2,3,4,5-tetrachloro-6-(trichloromethyl)pyridine Chemical compound ClC1=NC(C(Cl)(Cl)Cl)=C(Cl)C(Cl)=C1Cl YMBFWRZKTZICHS-UHFFFAOYSA-N 0.000 abstract 1
- 206010025323 Lymphomas Diseases 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal methoxide Chemical class 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 201000008275 breast carcinoma Diseases 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 208000011932 ovarian sarcoma Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/905,906 US4717726A (en) | 1986-09-10 | 1986-09-10 | 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)pyridine having anti-tumor activity |
| EP87112757A EP0260524B1 (de) | 1986-09-10 | 1987-09-01 | 3,5-Dichloro-2,4-dimethoxy-6-(trichlormethyl)pyridine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE99679T1 true ATE99679T1 (de) | 1994-01-15 |
Family
ID=25421670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87112757T ATE99679T1 (de) | 1986-09-10 | 1987-09-01 | 3,5-dichloro-2,4-dimethoxy-6(trichlormethyl)pyridine. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4717726A (de) |
| EP (1) | EP0260524B1 (de) |
| JP (1) | JPH0798805B2 (de) |
| AT (1) | ATE99679T1 (de) |
| CA (1) | CA1314049C (de) |
| DE (1) | DE3788693T2 (de) |
| ES (1) | ES2061457T3 (de) |
| HK (1) | HK75296A (de) |
| IE (1) | IE62519B1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6235761B1 (en) * | 1996-06-03 | 2001-05-22 | Neil Hartman | Compound, composition and method for treating cancer |
| ATE474575T1 (de) * | 1999-01-21 | 2010-08-15 | Southern Res Inst | Pyridinverbindungen, ihre verfahren zur herstellung und anwendung |
| WO2000043010A1 (en) * | 1999-01-21 | 2000-07-27 | Southern Research Institute | Acyl derivatives of 4-demethylpenclomedine, use thereof and preparation thereof |
| US7122563B2 (en) * | 2005-02-01 | 2006-10-17 | Southern Research Institute | Derivatives of 4-demethylpenclomedine, use thereof and preparation thereof |
| EP1981850B1 (de) | 2005-12-13 | 2017-03-22 | Dekk-Tec, Inc. | Demethylpenclomedin-analoga und ihre verwendung als mittel gegen krebs |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4190662A (en) * | 1978-03-23 | 1980-02-26 | The Dow Chemical Company | Halomethyl substituted dialkoxypyridines |
| US4143144A (en) * | 1978-03-23 | 1979-03-06 | The Dow Chemical Company | Ethers of 4-halomethylpyridines |
-
1986
- 1986-09-10 US US06/905,906 patent/US4717726A/en not_active Expired - Lifetime
-
1987
- 1987-08-31 CA CA000545737A patent/CA1314049C/en not_active Expired - Fee Related
- 1987-09-01 AT AT87112757T patent/ATE99679T1/de active
- 1987-09-01 ES ES87112757T patent/ES2061457T3/es not_active Expired - Lifetime
- 1987-09-01 DE DE87112757T patent/DE3788693T2/de not_active Expired - Fee Related
- 1987-09-01 EP EP87112757A patent/EP0260524B1/de not_active Expired - Lifetime
- 1987-09-09 IE IE241087A patent/IE62519B1/en not_active IP Right Cessation
- 1987-09-10 JP JP62227547A patent/JPH0798805B2/ja not_active Expired - Lifetime
-
1996
- 1996-05-02 HK HK75296A patent/HK75296A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US4717726A (en) | 1988-01-05 |
| JPS63101364A (ja) | 1988-05-06 |
| CA1314049C (en) | 1993-03-02 |
| DE3788693D1 (de) | 1994-02-17 |
| HK75296A (en) | 1996-05-10 |
| EP0260524A2 (de) | 1988-03-23 |
| JPH0798805B2 (ja) | 1995-10-25 |
| DE3788693T2 (de) | 1994-04-28 |
| ES2061457T3 (es) | 1994-12-16 |
| IE872410L (en) | 1988-03-10 |
| EP0260524A3 (en) | 1989-10-11 |
| EP0260524B1 (de) | 1994-01-05 |
| IE62519B1 (en) | 1995-02-08 |
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