AU2000265100A1 - N sulfonyl aminoacid derivatives as inhibitors of metalloproteinase - Google Patents

N sulfonyl aminoacid derivatives as inhibitors of metalloproteinase

Info

Publication number
AU2000265100A1
AU2000265100A1 AU2000265100A AU6510000A AU2000265100A1 AU 2000265100 A1 AU2000265100 A1 AU 2000265100A1 AU 2000265100 A AU2000265100 A AU 2000265100A AU 6510000 A AU6510000 A AU 6510000A AU 2000265100 A1 AU2000265100 A1 AU 2000265100A1
Authority
AU
Australia
Prior art keywords
metalloproteinase
sulfonyl
inhibitors
aminoacid derivatives
aminoacid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2000265100A
Other languages
English (en)
Inventor
Gary A. De Crecenzo
Susan C. Howard
Joseph J Mcdonald
Huey S. Shieh
William C. Stallings
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2000/016323 external-priority patent/WO2001005389A2/fr
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of AU2000265100A1 publication Critical patent/AU2000265100A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2000265100A 2000-07-12 2000-08-01 N sulfonyl aminoacid derivatives as inhibitors of metalloproteinase Abandoned AU2000265100A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
WOUS00/16323 2000-07-12
PCT/US2000/016323 WO2001005389A2 (fr) 1999-07-16 2000-07-12 Methode de changement de la conformation d'une metalloproteinase matricielle
PCT/US2000/021024 WO2002003994A1 (fr) 2000-07-12 2000-08-01 Derives d'acides amines n sulfonyle inhibiteurs des metalloproteinases

Publications (1)

Publication Number Publication Date
AU2000265100A1 true AU2000265100A1 (en) 2002-01-21

Family

ID=21741484

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2000265100A Abandoned AU2000265100A1 (en) 2000-07-12 2000-08-01 N sulfonyl aminoacid derivatives as inhibitors of metalloproteinase

Country Status (2)

Country Link
AU (1) AU2000265100A1 (fr)
WO (1) WO2002003994A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006074518A1 (fr) 2005-01-14 2006-07-20 Matthew Henderson Scelle de transpondeur, et logement pour transpondeur
FI127924B (en) * 2014-02-27 2019-05-31 Oy Medix Biochemica Ab METHOD OF MEASURING MMP-8 ACTIVATION

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR980009238A (ko) * 1995-07-28 1998-04-30 우에노 도시오 설포닐아미노산 유도체
PT757984E (pt) * 1995-08-08 2003-02-28 Ono Pharmaceutical Co Derivados de acido hidroxamico uteis para inibir a gelatinase
BR9707010B1 (pt) * 1996-01-23 2009-05-05 compostos, composição farmacêutica e composições para inibir metaloproteinase e colagenase do tipo iv.
JP2000515153A (ja) * 1996-07-22 2000-11-14 モンサント カンパニー チオールスルホンアミド メタロプロテアーゼインヒビター
ATE287885T1 (de) * 1997-03-04 2005-02-15 Pharmacia Corp Hydroxamsäure-sulfonamid-derivate mit amidiertem aromatischen ring
KR100279519B1 (ko) * 1998-02-18 2001-02-01 이본수 비산계니트로화공정에의한방향족화합물의니트로화방법
JPH11236369A (ja) * 1998-02-23 1999-08-31 Kotobuki Seiyaku Kk スルホンアミド誘導体及びその製造法並びにこれを含有する医薬組成物
JPH11246527A (ja) * 1998-03-02 1999-09-14 Shionogi & Co Ltd Ｍｍｐ−８阻害剤

Also Published As

Publication number Publication date
WO2002003994A1 (fr) 2002-01-17

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