AU2001287635A1 - Method for producing enantiomer-free 6,8 dihydroxy octanoic acid esters by meansof asymmetric, catalytic hydrogenation - Google Patents
Method for producing enantiomer-free 6,8 dihydroxy octanoic acid esters by meansof asymmetric, catalytic hydrogenationInfo
- Publication number
- AU2001287635A1 AU2001287635A1 AU2001287635A AU8763501A AU2001287635A1 AU 2001287635 A1 AU2001287635 A1 AU 2001287635A1 AU 2001287635 A AU2001287635 A AU 2001287635A AU 8763501 A AU8763501 A AU 8763501A AU 2001287635 A1 AU2001287635 A1 AU 2001287635A1
- Authority
- AU
- Australia
- Prior art keywords
- sub
- asymmetric
- meansof
- dihydroxy
- free
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- LJWTVHKBGBUURN-UHFFFAOYSA-N 6,8-Dihydroxyoctanoic acid Chemical class OCCC(O)CCCCC(O)=O LJWTVHKBGBUURN-UHFFFAOYSA-N 0.000 title 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 238000009876 asymmetric hydrogenation reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/716—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10036516A DE10036516A1 (de) | 2000-07-27 | 2000-07-27 | Verfahren zur Herstellung von enantiomerenreinen 6,8-Dihydroxyoctansäureestern durch assymetrische katalytische Hydrierung |
| DE10036516 | 2000-07-27 | ||
| PCT/EP2001/008244 WO2002010113A1 (de) | 2000-07-27 | 2001-07-17 | Verfahren zur herstellung von enantiomerenreinen 6,8-dihydroxyoctansäureestern durch asymmetrische katalytische hydrierung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001287635A1 true AU2001287635A1 (en) | 2002-02-13 |
Family
ID=7650351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001287635A Abandoned AU2001287635A1 (en) | 2000-07-27 | 2001-07-17 | Method for producing enantiomer-free 6,8 dihydroxy octanoic acid esters by meansof asymmetric, catalytic hydrogenation |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6965029B2 (de) |
| EP (1) | EP1303475B1 (de) |
| JP (1) | JP2004505104A (de) |
| AT (1) | ATE297370T1 (de) |
| AU (1) | AU2001287635A1 (de) |
| BR (1) | BR0112773A (de) |
| CA (1) | CA2417269A1 (de) |
| CZ (1) | CZ2003191A3 (de) |
| DE (2) | DE10036516A1 (de) |
| EE (1) | EE200300038A (de) |
| ES (1) | ES2241866T3 (de) |
| HU (1) | HUP0301503A2 (de) |
| PL (1) | PL358717A1 (de) |
| PT (1) | PT1303475E (de) |
| WO (1) | WO2002010113A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1510517A1 (de) * | 2003-09-01 | 2005-03-02 | Lonza AG | Verfahren zur asymmetrischen Hydrierung von Beta-Aminoketonen |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6163690A (ja) | 1984-09-04 | 1986-04-01 | Takasago Corp | ルテニウム−ホスフイン錯体 |
| JPS62265293A (ja) | 1986-05-13 | 1987-11-18 | Takasago Corp | ルテニウム−ホスフイン錯体 |
| JPS6341487A (ja) | 1986-08-06 | 1988-02-22 | Takasago Corp | ルテニウム−ホスフイン錯体 |
| DE3629116A1 (de) * | 1986-08-27 | 1988-03-10 | Asta Pharma Ag | Verfahren zur herstellung enantiomerenreiner r-(+)-(alpha)-liponsaeure und s-(-)-(alpha)-liponsaeure (thioctsaeure) sowie nonen- beziehungsweise mesylderivate als zwischenprodukte hierfuer |
| EP0272787B1 (de) | 1986-11-14 | 1992-05-06 | Takasago International Corporation | Katalytische Produktion von optisch aktiven Carbonsäuren |
| JPH0757758B2 (ja) | 1988-10-24 | 1995-06-21 | 高砂香料工業株式会社 | ルテニウム―ホスフィン錯体 |
| DE59010810D1 (de) | 1989-11-09 | 1998-04-16 | Asta Medica Ag | Arzneimittel enthaltend als Wirkstoff R-alpha-Liponsäure oder S-alpha-Liponsäure |
| JP2775335B2 (ja) * | 1990-08-01 | 1998-07-16 | 高砂香料工業株式会社 | ルテニウム―ホスフィン錯体及びその製造中間体 |
| DE4037440A1 (de) | 1990-11-24 | 1992-05-27 | Basf Ag | Verfahren zur herstellung von (6s)-6,8-dihydroxyoctansaeureestern |
| DE4330730A1 (de) | 1993-09-10 | 1995-03-16 | Bayer Ag | Neue Bisphosphine für asymmetrische Hydrierkatalysatoren |
| IT1270082B (it) | 1994-07-12 | 1997-04-28 | Univ Degli Studi Milano | Difosfine eteroaromatiche come leganti chirali, complessi tra dette difosfine e metalli di transizione ed impiego di detti complessi come catalizzatori chirali |
| DE19709069C2 (de) | 1997-03-06 | 2000-04-06 | Asta Medica Ag | Enantiomerenreine 3-Hydroxyoctandisäurediester, Verfahren zur Herstellung derselben durch asymmetrische katalytische Hydrierung sowie Verfahren zur Herstellung von R-(+)- und S-(-)-alpha-Liponsäure |
-
2000
- 2000-07-27 DE DE10036516A patent/DE10036516A1/de not_active Withdrawn
-
2001
- 2001-07-17 AU AU2001287635A patent/AU2001287635A1/en not_active Abandoned
- 2001-07-17 ES ES01967196T patent/ES2241866T3/es not_active Expired - Lifetime
- 2001-07-17 WO PCT/EP2001/008244 patent/WO2002010113A1/de not_active Ceased
- 2001-07-17 EE EEP200300038A patent/EE200300038A/xx unknown
- 2001-07-17 CZ CZ2003191A patent/CZ2003191A3/cs unknown
- 2001-07-17 JP JP2002516245A patent/JP2004505104A/ja active Pending
- 2001-07-17 EP EP01967196A patent/EP1303475B1/de not_active Expired - Lifetime
- 2001-07-17 US US10/333,812 patent/US6965029B2/en not_active Expired - Fee Related
- 2001-07-17 PT PT01967196T patent/PT1303475E/pt unknown
- 2001-07-17 BR BR0112773-0A patent/BR0112773A/pt not_active IP Right Cessation
- 2001-07-17 CA CA002417269A patent/CA2417269A1/en not_active Abandoned
- 2001-07-17 AT AT01967196T patent/ATE297370T1/de not_active IP Right Cessation
- 2001-07-17 DE DE50106461T patent/DE50106461D1/de not_active Expired - Fee Related
- 2001-07-17 HU HU0301503A patent/HUP0301503A2/hu unknown
- 2001-07-17 PL PL01358717A patent/PL358717A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EE200300038A (et) | 2004-10-15 |
| WO2002010113A1 (de) | 2002-02-07 |
| US6965029B2 (en) | 2005-11-15 |
| CA2417269A1 (en) | 2003-01-24 |
| CZ2003191A3 (cs) | 2003-04-16 |
| EP1303475B1 (de) | 2005-06-08 |
| PT1303475E (pt) | 2005-09-30 |
| US20040030178A1 (en) | 2004-02-12 |
| DE10036516A1 (de) | 2002-02-07 |
| EP1303475A1 (de) | 2003-04-23 |
| HUP0301503A2 (en) | 2003-08-28 |
| DE50106461D1 (de) | 2005-07-14 |
| PL358717A1 (en) | 2004-08-09 |
| JP2004505104A (ja) | 2004-02-19 |
| ATE297370T1 (de) | 2005-06-15 |
| BR0112773A (pt) | 2003-06-24 |
| ES2241866T3 (es) | 2005-11-01 |
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