AU2003226018B2 - Collagen biofabric and methods of preparation and use therefor - Google Patents

Collagen biofabric and methods of preparation and use therefor Download PDF

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Publication number
AU2003226018B2
AU2003226018B2 AU2003226018A AU2003226018A AU2003226018B2 AU 2003226018 B2 AU2003226018 B2 AU 2003226018B2 AU 2003226018 A AU2003226018 A AU 2003226018A AU 2003226018 A AU2003226018 A AU 2003226018A AU 2003226018 B2 AU2003226018 B2 AU 2003226018B2
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AU
Australia
Prior art keywords
composition
amniotic membrane
biofabric
membrane
collagen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2003226018A
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English (en)
Other versions
AU2003226018A1 (en
Inventor
Robert J. Hariri
Aleksandr M. Kaplunovsky
Patricia A. Murphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celularity Inc
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Celularity Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celularity Inc filed Critical Celularity Inc
Publication of AU2003226018A1 publication Critical patent/AU2003226018A1/en
Application granted granted Critical
Publication of AU2003226018B2 publication Critical patent/AU2003226018B2/en
Priority to AU2008202604A priority Critical patent/AU2008202604B2/en
Assigned to Celularity, Inc. reassignment Celularity, Inc. Request for Assignment Assignors: ANTHROGENESIS CORPORATION
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/60Liquid-swellable gel-forming materials, e.g. super-absorbents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813Epithelial cells, e.g. keratinocytes, urothelial cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/40Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/90Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
    • C12N2533/92Amnion; Decellularised dermis or mucosa
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/20Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
    • Y10T442/2525Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
AU2003226018A 2002-03-26 2003-03-26 Collagen biofabric and methods of preparation and use therefor Expired AU2003226018B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2008202604A AU2008202604B2 (en) 2002-03-26 2008-06-12 Collagen biofabric and methods of preparation and use therefor

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/106,653 2002-03-26
US10/106,653 US20030187515A1 (en) 2002-03-26 2002-03-26 Collagen biofabric and methods of preparing and using the collagen biofabric
PCT/US2003/009304 WO2003082201A2 (fr) 2002-03-26 2003-03-26 Texture biologique collagene et procedes permettant de la preparer et de l'utiliser

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2008202604A Division AU2008202604B2 (en) 2002-03-26 2008-06-12 Collagen biofabric and methods of preparation and use therefor

Publications (2)

Publication Number Publication Date
AU2003226018A1 AU2003226018A1 (en) 2003-10-13
AU2003226018B2 true AU2003226018B2 (en) 2008-03-13

Family

ID=28452543

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2003226018A Expired AU2003226018B2 (en) 2002-03-26 2003-03-26 Collagen biofabric and methods of preparation and use therefor
AU2008202604A Expired AU2008202604B2 (en) 2002-03-26 2008-06-12 Collagen biofabric and methods of preparation and use therefor
AU2011201662A Expired AU2011201662B2 (en) 2002-03-26 2011-04-06 Collagen biofabric and methods of preparation and use therefor

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2008202604A Expired AU2008202604B2 (en) 2002-03-26 2008-06-12 Collagen biofabric and methods of preparation and use therefor
AU2011201662A Expired AU2011201662B2 (en) 2002-03-26 2011-04-06 Collagen biofabric and methods of preparation and use therefor

Country Status (15)

Country Link
US (2) US20030187515A1 (fr)
EP (4) EP2702871B1 (fr)
JP (3) JP4615223B2 (fr)
KR (1) KR100999247B1 (fr)
CN (1) CN1791331A (fr)
AU (3) AU2003226018B2 (fr)
CA (1) CA2479903C (fr)
DK (2) DK2702871T3 (fr)
ES (2) ES2526088T3 (fr)
IL (2) IL164220A0 (fr)
MX (1) MXPA04009188A (fr)
NZ (1) NZ535799A (fr)
PT (1) PT2702871T (fr)
WO (1) WO2003082201A2 (fr)
ZA (1) ZA200407650B (fr)

Families Citing this family (283)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080152629A1 (en) * 2000-12-06 2008-06-26 James Edinger Placental stem cell populations
DK1349918T3 (da) * 2000-12-06 2014-11-10 Anthrogenesis Corp Fremgangsmåde til indsamling af stamceller fra moderkagen
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
EP2316919B1 (fr) * 2001-02-14 2015-10-07 Anthrogenesis Corporation Placenta post-gravidique de mammifère, son utilisation et céllules souches placentaires correspondantes
EP3246396B1 (fr) * 2001-02-14 2020-01-29 Celularity, Inc. Rénovation et repopulation de tissus décellularisés et d'organes cadavériques par des cellules souches
US6942802B2 (en) * 2001-04-13 2005-09-13 Wyeth Holdings Corporation Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography
JP3888573B2 (ja) * 2001-06-29 2007-03-07 富士電機ホールディングス株式会社 ハンダ組成物
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
EP1496878A4 (fr) * 2002-04-12 2007-12-26 Celgene Corp Techniques d'identification de modulateurs d'angiogenese, composes decouverts par ces techniques et techniques de traitement utilisant ces composes
JP2005522215A (ja) * 2002-04-12 2005-07-28 セルジーン・コーポレーション 幹細胞及び前駆細胞の分化のモジュレーション、アッセイ、並びにそれらの使用
AU2003298775B2 (en) 2002-11-26 2008-07-17 Anthrogenesis Corporation Cytotherapeutics, cytotherapeutic units and methods for treatments using them
GB0321337D0 (en) * 2003-09-11 2003-10-15 Massone Mobile Advertising Sys Method and system for distributing advertisements
GB0322145D0 (en) * 2003-09-22 2003-10-22 Howmedica Internat S De R L Apparatus for use in the regeneration of structured human tissue
ES2396689T3 (es) 2003-12-11 2013-02-25 Isto Technologies Inc. Sistema de cartílago particulado
US7775965B2 (en) * 2004-03-09 2010-08-17 The Board Of Regents Of The University Of Oklahoma Decellularized grafts from umbilical cord vessels and process for preparing and using same
US20050287223A1 (en) * 2004-06-23 2005-12-29 Peyman Gholam A Use of amniotic membrane as biocompatible devices
US8802651B2 (en) * 2004-06-30 2014-08-12 Abbott Medical Optics Inc. Hyaluronic acid in the enhancement of lens regeneration
US8512730B2 (en) 2004-07-12 2013-08-20 Isto Technologies, Inc. Methods of tissue repair and compositions therefor
US20060190017A1 (en) * 2004-11-19 2006-08-24 Cyr John S Fibrin sealants and platelet concentrates applied to effect hemostasis at the interface of an implantable medical device with body tissue
JP2006176499A (ja) * 2004-11-25 2006-07-06 Nippon Seibutsu Seizai:Kk 眼疾患治療剤
US20070015685A1 (en) * 2005-04-04 2007-01-18 Naomi Balaban Bone cement compositions and the like comprising an RNAIII-inhibiting peptide
WO2006129673A1 (fr) * 2005-05-30 2006-12-07 Arblast Co., Ltd. Matériel pour la reconstruction de tissus et son utilisation
AU2006265601A1 (en) * 2005-06-30 2007-01-11 Anthrogenesis Corporation Repair of tympanic membrane using placenta derived collagen biofabric
US7928280B2 (en) * 2005-07-13 2011-04-19 Anthrogenesis Corporation Treatment of leg ulcers using placenta derived collagen biofabric
US20070021762A1 (en) * 2005-07-13 2007-01-25 Qing Liu Ocular plug formed from placenta derived collagen biofabric
GB0514567D0 (en) * 2005-07-15 2005-08-24 Univ Nottingham Surgical membrane
US7837673B2 (en) 2005-08-08 2010-11-23 Innovative Therapies, Inc. Wound irrigation device
WO2007023750A1 (fr) * 2005-08-26 2007-03-01 National University Corporation University Of Toyama Amnion seche et procede de sechage de l’amnion
JP4977345B2 (ja) * 2005-08-26 2012-07-18 国立大学法人富山大学 乾燥羊膜及び羊膜の乾燥処理方法
EP1916964A4 (fr) 2005-08-26 2015-11-04 Zimmer Inc Implants et procedes pour la reparation, le remplacement et le traitement de maladies articulaires
US20070074980A1 (en) * 2005-09-02 2007-04-05 Bankoski Brian R Implant rehydration packages and methods of use
US7682304B2 (en) * 2005-09-21 2010-03-23 Medtronic, Inc. Composite heart valve apparatus manufactured using techniques involving laser machining of tissue
CA2999420A1 (fr) 2005-09-27 2007-04-05 Tissuetech, Inc. Preparations de membrane amniotique et compositions purifiees, et procedes d'utilisation
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
CN101326281A (zh) * 2005-10-13 2008-12-17 人类起源公司 用源自胎盘的干细胞制备少突胶质细胞
DK1957633T3 (en) 2005-10-13 2014-03-17 Anthrogenesis Corp Immunomodulation USING PLACE SPEECH STEM CELLS
EP1948259B1 (fr) * 2005-10-26 2017-03-22 Genesis Technologies Limited Matrices de regeneration de tissus acellulaires bioabsorbables produites par incubation de produits sanguins acellulaires
CN101389754A (zh) 2005-12-29 2009-03-18 人类起源公司 胎盘干细胞和第二来源干细胞的联合培养
PT2471904T (pt) 2005-12-29 2019-02-25 Celularity Inc População de células estaminais placentárias
CA2633980A1 (fr) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Composition amelioree pour la collecte et la conservation de cellules souches placentaires et procedes d'utilisation de cette composition
CN101501185A (zh) * 2006-06-09 2009-08-05 人类起源公司 胎盘巢(placental niche)及其培养干细胞的用途
US7993918B2 (en) 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
WO2008021391A1 (fr) * 2006-08-15 2008-02-21 Anthrogenesis Corporation Biomatériau à base de cordon ombilical pour usage médical
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
US20080131522A1 (en) * 2006-10-03 2008-06-05 Qing Liu Use of placental biomaterial for ocular surgery
WO2008060377A2 (fr) 2006-10-04 2008-05-22 Anthrogenesis Corporation Compositions de tissu du cordon ombilical ou placentaire
KR20230146124A (ko) * 2006-10-06 2023-10-18 셀룰래리티 인코포레이티드 천연(텔로펩티드) 태반 콜라겐 조성물
AU2013203211B2 (en) * 2006-10-06 2015-05-28 Celularity Inc. Native (telopeptide) placental collagen compositions
ZA200902233B (en) 2006-10-23 2010-07-28 Anthrogenesis Corp Methods and compositions for treatment of bone defects with placental cell populations
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
BRPI0722363B8 (pt) * 2006-12-22 2021-06-22 Laboratoire Medidom S A patch de correção de cartilagem laminado implantável
KR100795708B1 (ko) * 2006-12-26 2008-01-17 주식회사 알앤엘바이오 인간 양막 상피세포 유래 성체 줄기세포의 분리 및 배양방법
AU2008216748A1 (en) 2007-02-12 2008-08-21 Anthrogenesis Corporation Hepatocytes and chondrocytes from adherent placental stem cells; and CD34+, CD45- placental stem cell-enriched cell populations
EP3763376A1 (fr) * 2007-02-12 2021-01-13 Celularity, Inc. Traitement de maladies inflammatoires au moyen de cellules souches placentaires
AU2008240191B2 (en) 2007-04-12 2013-09-19 Zimmer, Inc. Compositions and methods for tissue repair
AU2008237732B2 (en) * 2007-04-16 2014-05-22 Covidien Ag Methods and compositions for tissue regeneration
TWM322542U (en) * 2007-05-23 2007-11-21 Universal Scient Ind Co Ltd Testing machine
DE102007037051A1 (de) * 2007-07-24 2009-01-29 Aesculap Ag Flächiges Implantat
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
EP4559488A3 (fr) 2007-09-07 2025-08-13 MiMedx Group, Inc. Greffons de tissu placentaire et procédés améliorés de préparation et d'utilisation de ceux-ci
US20090069843A1 (en) * 2007-09-10 2009-03-12 Agnew Charles W Fistula plugs including a hydration resistant component
CA2700613C (fr) * 2007-09-26 2022-09-20 Celgene Cellular Therapeutics Cellules angiogeniques provenant d'un perfusat placentaire humain
NZ599825A (en) 2007-09-28 2014-10-31 Anthrogenesis Corp Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
KR20170116221A (ko) * 2007-11-07 2017-10-18 안트로제네시스 코포레이션 조산 합병증의 치료에 있어서의 제대혈의 용도
JP5795166B2 (ja) * 2007-11-28 2015-10-14 オルガノジェネシス インク. 生命工学による組織コンストラクト並びに生産及び使用のための方法
US20090163990A1 (en) * 2007-12-19 2009-06-25 Chunlin Yang Decellularized omentum matrix and uses thereof
US9943401B2 (en) 2008-04-04 2018-04-17 Eugene de Juan, Jr. Therapeutic device for pain management and vision
US9095569B2 (en) 2008-04-18 2015-08-04 Collplant Ltd. Methods of generating and using procollagen
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
US20110129520A1 (en) * 2008-04-25 2011-06-02 Simon Bogdansky Anti-Adhesion Barrier Wound Dressing Comprising Processed Amniotic Tissue and Method of Use
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
CN103751842A (zh) * 2008-07-30 2014-04-30 米辛瑟斯有限公司 衍生自前胃胞外基质的组织支架
US20100080840A1 (en) * 2008-07-31 2010-04-01 Michael Cho Hybrid superporous hydrogel scaffold for cornea regeneration
KR20240052847A (ko) 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
WO2010021715A1 (fr) * 2008-08-20 2010-02-25 Anthrogenesis Corporation Traitement d'un accident vasculaire cérébral à l'aide de cellules placentaires isolées
CA2734446C (fr) 2008-08-22 2017-06-20 Anthrogenesis Corporation Methodes et compositions pour le traitement de deficits osseux au moyen de populations de cellules placentaires
US8858698B2 (en) * 2008-09-05 2014-10-14 Mentor Worldwide Llc Acellular matrix glue
US7927414B2 (en) * 2008-09-05 2011-04-19 Ethicon, Inc. Method of manufacturing acellular matrix glue
AU2009316541B2 (en) * 2008-11-19 2015-08-06 Celularity Inc. Amnion derived adherent cells
NZ592839A (en) * 2008-11-21 2012-10-26 Anthrogenesis Corp Treatment of diseases, disorders or conditions of the lung using placental cells
US9205177B2 (en) 2009-03-04 2015-12-08 Peytant Solutions, Inc. Stents modified with material comprising amnion tissue and corresponding processes
EP3489352A1 (fr) 2009-03-25 2019-05-29 Celularity, Inc. Élimination de tumeurs au moyen de cellules tueuses intermédiaires tirées du placenta humain et composés immunomodulateurs
MX2011010197A (es) * 2009-03-31 2011-11-18 Univ Minnesota Descelularizacion y recelularizacion de organos y tejidos.
US9039783B2 (en) * 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
US20100323446A1 (en) 2009-06-05 2010-12-23 Jill Renee Barnett Method of collecting placental cells
US8586360B2 (en) 2009-07-02 2013-11-19 Anthrogenesis Corporation Method of producing erythrocytes without feeder cells
KR101103571B1 (ko) * 2009-09-23 2012-01-09 한림대학교 산학협력단 피부조직 재생용 구조체 및 이를 이용한 인공피부
US20130066283A1 (en) 2009-10-23 2013-03-14 Nexisvision, Inc. Corneal Denervation for Treatment of Ocular Pain
EP2490620A4 (fr) 2009-10-23 2017-03-22 Forsight Labs, Llc Écran thérapeutique adaptable pour la vision et la douleur
WO2011074208A1 (fr) * 2009-12-18 2011-06-23 国立大学法人東北大学 Procédé pour la préparation d'un matériau de transplantation cornéenne par mise en transparence d'un derme cutané ou d'un amnios
DK3284818T3 (da) 2010-01-26 2022-06-20 Celularity Inc Behandling af knoglerelateret kræft ved hjælp af placenta stamceller
CA2790436A1 (fr) 2010-02-18 2011-08-25 Osiris Therapeutics, Inc. Produits de membrane chorionique immunocompatible
LT2556145T (lt) 2010-04-07 2016-11-10 Anthrogenesis Corporation Angiogenezė naudojant placentos kamienines ląsteles
MX2012011543A (es) 2010-04-08 2013-05-06 Anthrogenesis Corp Tratamiento de sarcoidosis empleando celulas madre placentarias.
US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8840665B2 (en) 2010-06-11 2014-09-23 Liventa Bioscience, Inc. Method of tendon repair with amnion and chorion constructs
US20130156863A1 (en) * 2010-06-30 2013-06-20 Tissuetech, Inc. Methods of preparing chorion tissue and products derived therefrom
AU2011276246B2 (en) * 2010-07-08 2014-12-04 Lifecell Corporation Method for shaping tissue matrices
ES2666746T3 (es) 2010-07-13 2018-05-07 Anthrogenesis Corporation Métodos para generar linfocitos citolíticos naturales
US20120035743A1 (en) * 2010-08-03 2012-02-09 AFcell Medical Amnion and chorion constructs and uses thereof in minimally invasive surgeries
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
US9433490B2 (en) 2010-12-22 2016-09-06 University Of Florida Research Foundation, Inc. Multilayered implant materials derived from amniotic membrane, methods of making the multilayered implant materials, and method of using multilayered implant materials
AR084754A1 (es) 2010-12-30 2013-06-05 Anthrogenesis Corp Composiciones que comprenden celulas madre de placenta y plasma rico en plaquetas, y sus metodos de uso
US20120171180A1 (en) 2010-12-30 2012-07-05 Sascha Abramson Compositions comprising amnion derived adherent cells and platelet-rich plasma
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
WO2012112410A2 (fr) * 2011-02-14 2012-08-23 Mimedx Group Inc. Compositions micronisées de tissu placentaire, et méthodes de fabrication et d'utilisation de celles-ci
KR102118457B1 (ko) * 2011-02-14 2020-06-03 미메딕스 그룹 인크. 가교제로 변형된 조직 이식편 및 그것의 제조 및 사용 방법
EP3311826B1 (fr) 2011-02-14 2020-04-29 MiMedx Group, Inc. Compositions de tissus placentaux micronisés et leurs procédés de fabrication et d'utilisation
WO2012149486A1 (fr) 2011-04-28 2012-11-01 Tissuetech, Inc. Procédés de modulation de remodélisation osseuse
US12044905B2 (en) 2011-04-28 2024-07-23 Journey1 Inc Contact lenses for refractive correction
JP6104896B2 (ja) 2011-06-01 2017-03-29 アントフロゲネシス コーポレーション 胎盤幹細胞を使用する疼痛の治療
EP2717888B1 (fr) * 2011-06-10 2020-09-09 Tissuetech, Inc. Procédés de traitement de tissus foetaux de support
WO2013055476A1 (fr) 2011-09-09 2013-04-18 Anthrogenesis Corporation Traitement de la sclérose latérale amyotrophique au moyen de cellules souches placentaires
US20130136773A1 (en) * 2011-09-30 2013-05-30 NuTech Spine, Inc. Expandable Placental Membrane and Methods of Making and Storing Same
US10517902B2 (en) * 2011-09-30 2019-12-31 Prime Merger Sub, Llc Expandable amnion membrane for treating non-healing wounds
US12290613B2 (en) 2011-10-06 2025-05-06 Mimedx Group, Inc. Micronized compositions composed of bone grafts and methods of making and using the same
US9585983B1 (en) * 2011-10-12 2017-03-07 BioDlogics, LLC Wound covering and method of preparation
US9186382B2 (en) 2011-12-02 2015-11-17 Mimedx Group, Inc. Placental tissue grafts produced by chemical dehydration/freeze-drying and methods for making and using the same
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
CA2857636C (fr) 2011-12-22 2020-06-23 Mimedx Group Inc. Greffes de tissu placentaire deshydratees reticulees et procedes pour fabriquer et utiliser celles-ci
CN113699105A (zh) * 2011-12-23 2021-11-26 人类起源公司 包含脱细胞并再群体化的胎盘血管支架的类器官
US9416410B2 (en) * 2012-02-14 2016-08-16 Genetics Development Corporation Cutoff point delta Ct. method for HER2 PCR testing in breast cancer
EP3338548B1 (fr) * 2012-02-23 2020-04-08 Celularity, Inc. Identification de composés antitumoraux à partir de placenta
US10071184B2 (en) 2012-02-29 2018-09-11 Collagen Matrix, Inc. Collagen-coated tissue-based membranes
US8961617B2 (en) 2012-03-08 2015-02-24 Liventa Bioscience, Inc. Amnion and chorion constructs and uses thereof in abdominal surgery
US10576037B2 (en) * 2012-03-14 2020-03-03 MAM Holdings of West Florida, L.L.C. Compositions comprising placental collagen for use in wound healing
KR101404089B1 (ko) * 2012-04-02 2014-06-05 원광대학교산학협력단 양막 추출물을 함유하는 이중층 하이드로겔 습윤드레싱 및 그 제조방법
JP2015526088A (ja) 2012-08-13 2015-09-10 アントフロゲネシス コーポレーション ナチュラルキラー細胞及びその使用
CA2880157C (fr) 2012-08-15 2020-07-21 Mimedx Group, Inc. Greffes de tissu placentaire renforcees et procedes de fabrication et d'utilisation de celles-ci
US11338063B2 (en) 2012-08-15 2022-05-24 Mimedx Group, Inc. Placental tissue grafts modified with a cross-linking agent and methods of making and using the same
US9943551B2 (en) 2012-08-15 2018-04-17 Mimedx Group, Inc. Tissue grafts composed of micronized placental tissue and methods of making and using the same
US8904664B2 (en) 2012-08-15 2014-12-09 Mimedx Group, Inc. Dehydration device and methods for drying biological materials
WO2014039429A1 (fr) * 2012-09-04 2014-03-13 Anthrogenesis Corporation Procédés de génération de tissu
KR20150059754A (ko) 2012-09-04 2015-06-02 안트로제네시스 코포레이션 조직 생성 방법
EP2897625B1 (fr) 2012-09-10 2019-10-23 Wake Forest University Health Sciences Membrane amniotique et son utilisation dans des produits de construction de cicatrisation des plaies et d'ingénierie tissulaire
US9180145B2 (en) 2012-10-12 2015-11-10 Mimedx Group, Inc. Compositions and methods for recruiting and localizing stem cells
US10245306B2 (en) 2012-11-16 2019-04-02 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
US8946163B2 (en) 2012-11-19 2015-02-03 Mimedx Group, Inc. Cross-linked collagen comprising metallic anticancer agents
US9155799B2 (en) 2012-11-19 2015-10-13 Mimedx Group, Inc. Cross-linked collagen with at least one bound antimicrobial agent for in vivo release of the agent
US8940684B2 (en) 2012-11-19 2015-01-27 Mimedx Group, Inc. Cross-linked collagen comprising an antifungal agent
EP3838280A1 (fr) * 2012-12-07 2021-06-23 Celularity Inc. Traitement des lésions buccales au moyen de matrice extracellulaire placentaire
JP2016502844A (ja) 2012-12-14 2016-02-01 アントフロゲネシス コーポレーション アノイキス抵抗性胎盤幹細胞及びその使用
AU2013204922B2 (en) 2012-12-20 2015-05-14 Celgene Corporation Chimeric antigen receptors
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
CN103006349A (zh) * 2012-12-26 2013-04-03 天津市赛宁生物工程技术有限公司 体外培养的组织工程血管
KR102284982B1 (ko) * 2013-01-09 2021-08-03 넥스트젠 바이오로직스, 아이엔씨. 비-포유류 조직으로부터의 세포제거된 생체재료
US10517931B2 (en) 2013-01-17 2019-12-31 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US9827293B2 (en) 2013-01-17 2017-11-28 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US9655948B1 (en) 2013-01-17 2017-05-23 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US10206977B1 (en) 2013-01-18 2019-02-19 Mimedx Group, Inc. Isolated placental stem cell recruiting factors
US9662355B2 (en) 2013-01-18 2017-05-30 Mimedx Group, Inc. Methods for treating cardiac conditions
US10905800B1 (en) 2013-01-29 2021-02-02 BioDlogics, LLC Ocular covering and method of use
WO2014120946A1 (fr) * 2013-01-30 2014-08-07 NuTech Medical, Inc. Préparation de membrane placentaire et procédés de fabrication et d'utilisation associés
CN103127549A (zh) * 2013-02-01 2013-06-05 中山大学中山眼科中心 一种脱细胞睑板及其制备方法
CN115137753A (zh) 2013-02-05 2022-10-04 细胞结构公司 来自胎盘的自然杀伤细胞
US9498327B1 (en) 2013-03-05 2016-11-22 Biodlogics Llc Repair of tympanic membrane using human birth tissue material
US9789138B1 (en) 2013-03-06 2017-10-17 BioDlogics, LLC Neural repair construct and method of use
US9770472B1 (en) 2013-03-08 2017-09-26 Brahm Holdings, Llc Organ jacket and methods of use
AU2014248873B2 (en) 2013-03-13 2017-03-23 Allosource Fascia fibrous compositions and methods for their use and manufacture
US9855301B1 (en) 2013-03-13 2018-01-02 Biodlogics Llc Human birth tissue laminate and methods of use
DK2970883T3 (da) 2013-03-14 2021-08-09 Celularity Inc Forbedrede placenta stamceller og bruge deraf
NO2975611T3 (fr) * 2013-03-15 2018-06-09
US10029030B2 (en) * 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
CA2899713C (fr) 2013-03-15 2022-07-19 Allosource Matrice de collagene repeuplee de cellules pour reparation et regeneration des tissus mous
AU2014228022B9 (en) 2013-03-15 2016-11-03 NuTech Medical, Inc. Preparations derived from placental materials of making and using same
US9795638B1 (en) 2013-03-16 2017-10-24 BioDlogics, LLC Cardiothoracic construct and methods of use
CN104083803B (zh) * 2013-04-01 2016-04-27 陕西佰傲再生医学有限公司 一种用于眼表修复的生物膜及其制备方法
US10335433B2 (en) 2013-04-10 2019-07-02 Mimedx Group, Inc. NDGA polymers and metal complexes thereof
WO2014189835A2 (fr) * 2013-05-20 2014-11-27 Yale University Greffons anti-thrombose
US9446142B2 (en) 2013-05-28 2016-09-20 Mimedx Group, Inc. Polymer chelator conjugates
JP2016526387A (ja) 2013-06-24 2016-09-05 アントフロゲネシス コーポレーション 細胞培養のための細胞外マトリクス組成物ビーズ
JP6310072B2 (ja) 2013-06-26 2018-04-11 ネクシスビジョン, インコーポレイテッド 屈折矯正のためのコンタクトレンズ
JP6756612B2 (ja) 2013-08-30 2020-09-16 ミメディクス グループ インコーポレイテッド キレーターを含む微粒子化した胎盤性組成物
EP2857350A1 (fr) * 2013-09-10 2015-04-08 ESPCI Innov Utilisation de nanoparticules pour coller des gels
KR102161901B1 (ko) 2013-12-06 2020-10-05 알로소스 조직의 시트를 건조하는 방법
WO2015109329A1 (fr) 2014-01-17 2015-07-23 Mimedx Group, Inc. Méthode pour induire l'angiogenèse
WO2015120405A1 (fr) * 2014-02-07 2015-08-13 Amniolife Corporation Membranes de tissus à motifs et procédés et système pour leur réparation
US10894066B2 (en) 2014-03-06 2021-01-19 Amnio Technology Llc Amnion derived therapeutic compositions and methods of use
US9132156B1 (en) * 2014-06-15 2015-09-15 Amnio Technology Llc Acellular amnion derived therapeutic compositions
US9801910B2 (en) * 2014-03-17 2017-10-31 Ethicon, Inc. Decellularized pleural matrix
CN103861151B (zh) * 2014-03-27 2016-03-30 成都青山利康药业有限公司 一种脱细胞胎盘基质材料的制备方法
JP2017514876A (ja) * 2014-05-07 2017-06-08 オシリス セラピューティクス,インコーポレイテッド 治療用胎盤組成物、その製造法及び使用法
AU2014393404A1 (en) * 2014-05-07 2016-11-24 Osiris Therapeutics, Inc. Immunocompatible amniotic membrane products
US11083758B2 (en) 2014-05-14 2021-08-10 Prime Merger Sub, Llc Placental membrane preparations and methods of making and using same for regenerating cartilage and spinal intervertebral discs
SG10201801654RA (en) 2014-05-28 2018-04-27 Childrens Hospital Med Ct Methods and systems for converting precursor cells into gastric tissues through directed differentiation
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
US10363278B2 (en) 2014-06-15 2019-07-30 Amnio Technology Llc Frozen therapeutic dose and package
EP2979710B8 (fr) * 2014-07-29 2020-07-15 National Cheng Kung University Gel de tissu cellulaire contenant du collagène et de l'hyaluronane
JP7099822B2 (ja) * 2014-08-28 2022-07-12 ミメディクス グループ インコーポレイテッド コラーゲンで強化した組織移植片
US12083245B2 (en) 2014-10-02 2024-09-10 Wake Forest University Health Sciences Amniotic membrane powder and its use in wound healing and tissue engineering constructs
US20160095307A1 (en) 2014-10-07 2016-04-07 NuTech Medical, Inc. Method and composition for hypothermic storage of placental tissue
US10179191B2 (en) 2014-10-09 2019-01-15 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
CA2963002C (fr) * 2014-10-10 2021-08-17 Orthocell Limited Reparation sans suture de tissu mou
AU2015331848B2 (en) 2014-10-17 2022-03-03 Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center In vivo model of human small intestine using pluripotent stem cells and methods of making and using same
US10265438B1 (en) 2014-11-03 2019-04-23 BioDlogics, LLC Methods and compositions for the repair and replacement of connective tissue
US10765705B2 (en) 2014-11-24 2020-09-08 Prime Merger Sub, Llc Visco-supplement compositions, and methods of use thereof
JP6797803B2 (ja) 2014-12-31 2020-12-09 セルジーン コーポレイション ナチュラルキラー細胞を用いて血液障害、固形腫瘍、又は感染性疾患を治療する方法
WO2016111899A1 (fr) 2015-01-05 2016-07-14 Petrucci Gary M Procédés et matériels pour le traitement de troubles pulmonaires
US10517903B2 (en) 2015-09-14 2019-12-31 Amnio Technology Llc Amnion derived therapeutic composition and process of making same
US10736990B2 (en) * 2015-02-11 2020-08-11 Mimedx Group, Inc. Collagen and micronized placental tissue compositions and methods of making and using the same
WO2016138025A2 (fr) 2015-02-23 2016-09-01 Tissuetech, Inc. Appareils et méthodes de traitement de maladies et de troubles ophtalmiques
WO2016149194A1 (fr) 2015-03-13 2016-09-22 MAM Holdings of West Florida, L.L.C. Compositions de collagène et utilisations d'implants de biomatériaux
WO2016168752A1 (fr) * 2015-04-17 2016-10-20 The Regents Of The University Of California Membrane amniotique humaine décellularisée utilisée pour l'apport cellulaire, la culture de cellules et la prévention de l'inflammation
CN104826166B (zh) * 2015-05-06 2017-06-06 广州优适清生物科技有限公司 一种用于青光眼治疗的生物膜及其制备方法
TWI720984B (zh) 2015-05-20 2021-03-11 美商帝聖工業公司 用於防止上皮細胞增生及上皮-間質轉移之組合物及方法
CA2986702C (fr) 2015-05-21 2023-04-04 David Wang Fibres osseuses corticales demineralisees modifiees
CN105169493B (zh) * 2015-07-13 2018-02-27 江南大学 一种人工异种皮肤的制备方法
MY203748A (en) 2015-09-15 2024-07-17 Celularity Inc Treatment of diabetic peripheral neuropathy using placental cells
JP2018527394A (ja) 2015-09-23 2018-09-20 オシリス セラピューティクス,インコーポレイテッド 臍組織組成物及び使用方法
CA3000401C (fr) * 2015-09-29 2022-09-27 Anicell Biotech, Llc Articles de fabrication contenant des tissus foetaux decellularises et reconstitues et methodes de fabrication associees
WO2017075608A1 (fr) 2015-10-30 2017-05-04 New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery Timbre de manchon de suture et procédés de pose dans un flux de travail arthroscopique existant
US20170136070A1 (en) * 2015-11-18 2017-05-18 Dregalla Patent Holdco, LLC Acellular Regenerative Products and Methods of Their Manufacture
WO2017112934A1 (fr) * 2015-12-23 2017-06-29 Lifenet Health Membrane placentaire décellularisée et ses procédés de préparation et d'utilisation
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
US11357495B2 (en) 2016-02-01 2022-06-14 Medos International Sarl Tissue augmentation scaffolds for use with soft tissue fixation repair systems and methods
US20170273680A1 (en) 2016-02-01 2017-09-28 DePuy Synthes Products, Inc. Tissue augmentation tacks for use with soft tissue fixation repair systems and methods
US11484401B2 (en) 2016-02-01 2022-11-01 Medos International Sarl Tissue augmentation scaffolds for use in soft tissue fixation repair
US10993969B2 (en) 2016-02-05 2021-05-04 Gary M. Petrucci Methods and materials for treating nerve injuries and neurological disorders
CN109415685B (zh) 2016-05-05 2023-07-04 儿童医院医疗中心 用于体外制造胃底组织的方法和与其相关的组合物
CN105833353B (zh) * 2016-05-09 2018-04-20 拜欧迪赛尔(北京)生物科技有限公司 一种生物工程脱细胞真皮基质的制备及用途
CA3032160C (fr) 2016-08-24 2024-05-28 Arthrex, Inc. Tissu hybride a utiliser dans la reparation, la reconstruction ou la regeneration de suite a des processus degeneratifs ou blessures musculosquelettiques
ES3062307T3 (en) * 2016-11-02 2026-04-09 Axogen Corp Amnion tissue grafts and methods of preparing and using same
EP4553082A3 (fr) 2016-11-04 2025-08-20 Children's Hospital Medical Center Compositions d'organoïdes hépatiques et leurs procédés de fabrication et d'utilisation
CN106390195B (zh) * 2016-11-16 2019-08-23 四川大学 一种胶原膜的改性方法
EP3548507A4 (fr) 2016-12-05 2020-07-15 Children's Hospital Medical Center Organoïdes du côlon et leurs procédés de préparation et d'utilisation
CA3046078A1 (fr) 2016-12-05 2018-06-14 Celularity Inc. Traitement d'un lymphoedeme et d'etats associes a l'aide de cellules adherentes placentaires
CN108210995A (zh) * 2016-12-14 2018-06-29 成都青山利康药业有限公司 一种新型的复合生物组织修复材料及其制备方法和用途
US10772986B2 (en) 2017-01-26 2020-09-15 Allosource Fascia fibrous compositions and methods for their use and manufacture
US11299630B2 (en) 2017-01-26 2022-04-12 3Dbiofibr Inc. Templated assembly of collagen fibers and uses thereof
EP3578189B1 (fr) * 2017-02-03 2022-08-31 Biocellix SpA Matrice ou membrane de collagène à propriétés antimicrobiennes
CN107137768B (zh) * 2017-04-12 2020-07-07 苏州诺普再生医学有限公司 一种脱细胞羊膜粉的制备方法
JP7248586B2 (ja) 2017-04-14 2023-03-29 チルドレンズ ホスピタル メディカル センター 複数ドナー幹細胞組成物およびそれを作製する方法
JP7031138B2 (ja) 2017-05-11 2022-03-08 株式会社リコー 脱細胞化組織の製造方法、及び脱細胞化組織の製造装置
CN107233144A (zh) * 2017-05-31 2017-10-10 中山大学中山眼科中心 去细胞角膜基质透镜在治疗眼科疾病中的应用
US10478531B2 (en) 2017-06-22 2019-11-19 Gary M. Petrucci Methods and materials for treating blood vessels
CN109481737B (zh) * 2017-09-12 2021-07-06 中国人民解放军第三军医大学第一附属医院 一种仿生双层敷料及其制备方法
US10251917B1 (en) 2017-09-19 2019-04-09 Gary M. Petrucci Methods and materials for treating tumors
WO2019067792A1 (fr) 2017-09-28 2019-04-04 Celularity, Inc. Suppression de tumeur à l'aide de cellules tueuses naturelles intermédiaires dérivées du placenta humain (pink) en combinaison avec un anticorps
EP3694603B1 (fr) 2017-10-10 2026-04-08 Children's Hospital Medical Center Compositions de tissus oesophagiens et/ou d'organoïdes et leurs procédés de fabrication
GB2582521B (en) 2017-11-14 2022-07-13 Cook Biotech Inc Preserved tissue products and related methods
CN108051509B (zh) * 2017-11-21 2020-06-23 陈溉 一种治疗褥疮的药物的特征图谱检测方法及其应用
CN107929811A (zh) * 2017-12-15 2018-04-20 厦门大学 一种组织工程角膜
EP3727394A4 (fr) 2017-12-21 2021-09-08 Children's Hospital Medical Center Organoïdes humains numérisés et méthodes d'utilisation de ceux-ci
US20210095258A1 (en) 2018-02-22 2021-04-01 Celularity Inc. Post partum tissue-derived induced pluripotent stem cells and uses thereof
US11602548B1 (en) 2018-02-26 2023-03-14 Convatec, Inc Fibrous birth tissue composition and method of use
EP4678727A3 (fr) 2018-07-26 2026-03-11 Children's Hospital Medical Center Tissus hépato-biliaire-pancréatiques et leurs procédés de fabrication
CN109065670B (zh) * 2018-08-08 2019-12-20 长春长光宇航复合材料有限公司 碳纤维复合材料网格蒙皮太阳能电池阵基板的制备方法
CA3112026A1 (fr) 2018-09-12 2020-03-19 Children's Hospital Medical Center Compositions d'organoides pour la production de cellules souches hematopoietiques et leurs derives
AU2019387491A1 (en) 2018-11-30 2021-05-27 Celularity Inc. Expansion of natural killer cells and ILC3 cells with novel aromatic compounds
CN109557107A (zh) * 2018-12-29 2019-04-02 南工大溧阳新材料研发中心有限公司 一种不锈钢/碳钢复合材料的探伤检测方法
US12600943B2 (en) 2019-02-01 2026-04-14 The University Of Hong Kong Innervated organoid compositions and methods of making same
US11511017B2 (en) 2019-03-12 2022-11-29 Arthrex, Inc. Ligament reconstruction
US12497597B2 (en) 2019-05-31 2025-12-16 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
AU2020283048A1 (en) 2019-05-31 2021-12-23 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
US20220265712A1 (en) 2019-06-14 2022-08-25 Celularity Inc. Populations of natural killer cells for treating cancers
US20220273716A1 (en) 2019-07-25 2022-09-01 Celularity Inc. Populations of natural killer cells comprising a cd38 chimeric antigen receptor
US20230355759A1 (en) 2019-07-31 2023-11-09 Celularity Inc. Populations of natural killer cells comprising a cleavage resistant cd16
US12576190B2 (en) 2019-08-15 2026-03-17 Axogen Corporation Tissue repair membrane adapted for adhesion and lubrication, and methods for preparing the same
CN110404119B (zh) * 2019-08-29 2023-04-07 上海越增生物科技有限公司 羊膜组织工程去免疫原皮肤支架的制备方法
WO2021113849A1 (fr) 2019-12-05 2021-06-10 Celularity Inc. Traitement du cancer du sein her2+ avec des populations de cellules tueuses naturelles comprenant un cd16 résistant au clivage
US20220000919A1 (en) 2020-01-29 2022-01-06 Celularity Inc. Placental derived natural killer cells for treatment of coronavirus infections
US20210244845A1 (en) * 2020-02-10 2021-08-12 Leslie MARCELIN Method Of Processing Amnion To Form A Suture
BR112022016166A2 (pt) 2020-02-14 2022-10-04 Kheiros Pater Inovacao S A Método de produção de biomaterial descelularizado, biomaterial descelularizado e uso do mesmo
CN115697265A (zh) * 2020-04-03 2023-02-03 组织技术公司 使用脐带产物治疗眼部表面病症的方法
WO2021226602A1 (fr) 2020-05-08 2021-11-11 Celularity Inc. Cellule souche adhérente dérivée du placenta (pda) pour le traitement d'adultes atteints d'une insuffisance respiratoire aiguë associée au sras-cov-2 et du sdra (covid-19)
AU2021376324A1 (en) * 2020-11-05 2023-06-08 Mimedx Group, Inc. Meshed placental membrane tissue grafts
TW202233828A (zh) 2020-11-12 2022-09-01 日商Adeka股份有限公司 去細胞化組織組成物
CN112641999B (zh) * 2020-12-04 2022-10-04 陕西佰傲再生医学有限公司 一种铺膜设备及其应用
CN116761644A (zh) 2020-12-11 2023-09-15 骨原生物医药公司 多层基于胶原蛋白的膜
MX2023012051A (es) * 2021-04-13 2024-01-08 Celularity Inc Injertos tisulares amnioticos multicapa y usos de estos.
WO2023278628A1 (fr) 2021-06-29 2023-01-05 Celularity Inc. Cellules tueuses naturelles dérivées de cellules souches hématopoïétiques placentaires humaines dans une rémission de leucémie aiguë myéloïde (lam) avec une maladie résiduelle minimale (mrd) ou une lam récurrente/réfractaire
US20250276063A1 (en) 2021-07-29 2025-09-04 Celularity Inc. Placenta-dervied nk cells as a senol ytic for therapeutic and other uses
CN114028618A (zh) * 2021-10-25 2022-02-11 广东普洛宇飞生物科技有限公司 一种基于羊膜基底膜的生物材料及其制备方法和应用
WO2023137344A1 (fr) 2022-01-11 2023-07-20 Celularity Inc. Constructions de cd16 résistant au clivage et leurs utilisations
CN115054730B (zh) * 2022-06-14 2023-08-18 健诺维(成都)生物科技有限公司 一种羊膜新材料及其制备方法
WO2024167694A2 (fr) * 2023-02-06 2024-08-15 Celularity Inc. Matrices extracellulaires placentaires pour l'administration oculaire d'agents thérapeutiques ophtalmiques
WO2025030604A1 (fr) * 2023-08-10 2025-02-13 赛克赛斯生物科技股份有限公司 Matériau de membrane amniotique réticulé, son procédé de préparation et son utilisation
WO2025212307A1 (fr) * 2024-04-02 2025-10-09 University Of Connecticut Timbre d'amnion et ses utilisations
CN118416309B (zh) * 2024-04-30 2024-12-20 广州悦清再生医学科技有限公司 一种脱细胞羊膜材料及其制备方法与在制备眼表修复材料中的应用
US20260053985A1 (en) * 2024-08-21 2026-02-26 Orbio Innovations, Llc Enhanced birth tissue allografts and methods of manufacture

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612028A (en) * 1988-02-17 1997-03-18 Genethics Limited Method of regenerating or replacing cartilage tissue using amniotic cells
US6152142A (en) * 1997-02-28 2000-11-28 Tseng; Scheffer C. G. Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3157524A (en) 1960-10-25 1964-11-17 Ethicon Inc Preparation of collagen sponge
US3800792A (en) 1972-04-17 1974-04-02 Johnson & Johnson Laminated collagen film dressing
DE2416313C3 (de) 1974-04-04 1978-11-23 Roland 8731 Euerdorf Satzinger Sicherheitseinrichtung für die Insassen von Fahrzeugen, insbesondere Kraftfahrzeugen
US4060081A (en) 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
DE2943520C2 (de) 1979-10-27 1982-05-19 Fa. Carl Freudenberg, 6940 Weinheim Verfahren zur Herstellung von Kollagenschwamm für medizinische oder kosmetische Zwecke
US4446234A (en) * 1981-10-23 1984-05-01 The United States Of America As Represented By The Department Of Health And Human Services Vitro cellular interaction with amnion membrane substrate
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US4883618A (en) 1983-02-02 1989-11-28 Minnesota Mining And Manufacturing Company Absorbable nerve repair device and method
US4837285A (en) 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4778467A (en) 1984-04-25 1988-10-18 The University Of Utah Prostheses and methods for promoting nerve regeneration and for inhibiting the formation of neuromas
IL78950A (en) * 1985-06-06 1991-12-15 Univ Jefferson Coating for prosthetic devices
JPS63260549A (ja) * 1987-04-17 1988-10-27 石川 統一 補綴材料およびその製造方法
EP0363400B1 (fr) 1987-04-28 1993-03-03 The Regents Of The University Of California Procede et appareil permettant de preparer un materiau de remplacement composite de peau
US5036056A (en) * 1987-07-08 1991-07-30 Martin Kludas Methods for treating damaged corneal, uterine, or cartilage tissue
US5116620A (en) 1989-11-21 1992-05-26 Bruce A. Barber Antimicrobial wound dressing
US5308627A (en) 1990-08-07 1994-05-03 Umbdenstock Jr Anthony J Nutritional supplement for optimizing cellular health
US5198465A (en) 1991-06-19 1993-03-30 Dioguardi Francesco S Compositions based on amino acids for preventing and treating precursor deficiencies in the synthesis of collagen
DE69215053T2 (de) 1991-09-26 1997-04-03 United States Surgical Corp. (N.D.Ges.D.Staates Delaware), Norwalk, Conn. Vorrichtung zum Reparieren von Nerven
US5418875A (en) 1992-09-04 1995-05-23 Honda Tsushin Kogyo Co., Ltd. Adapter for optical connector having float-type sleeve holder and panel fitting for mounting the same
US6124259A (en) * 1993-01-28 2000-09-26 Celtrix Pharmaceuticals, Inc. Method for treating ophthalmic disorders with IGFBP
JP3542170B2 (ja) * 1993-08-06 2004-07-14 株式会社アムニオテック 医用材料及びその製造方法
GB9400163D0 (en) 1994-01-06 1994-03-02 Geistlich Soehne Ag Membrane
IL112580A0 (en) * 1994-02-24 1995-05-26 Res Dev Foundation Amniotic membrane graft of wrap to prevent adhesions or bleeding of internal organs
US6203755B1 (en) * 1994-03-04 2001-03-20 St. Jude Medical, Inc. Electron beam sterilization of biological tissues
WO1995024873A1 (fr) * 1994-03-14 1995-09-21 Cryolife, Inc. Tissu traite pour une implantation et procedes pour sa preparation
JP2905718B2 (ja) * 1995-03-31 1999-06-14 東洋紡績株式会社 医用材料およびその製造方法
CA2173508A1 (fr) 1995-03-31 1996-10-01 Tooru Yui Dispositif medical et procede d'obtention
JPH09122227A (ja) 1995-10-31 1997-05-13 Bio Eng Lab:Kk 医用材料およびその製造方法
JP3476631B2 (ja) * 1995-12-21 2003-12-10 株式会社アムニオテック ヒト由来の天然コラーゲン膜からなる医用材料
EP0907721A1 (fr) * 1996-05-28 1999-04-14 Brown University Research Foundation Charpentes biodegradables a base de hyaluronan destinees a la reparation tissulaire
JP3563216B2 (ja) * 1996-10-14 2004-09-08 株式会社アムニオテック 医用代替膜及びその製造方法
US5804594A (en) 1997-01-22 1998-09-08 Murad; Howard Pharmaceutical compositions and methods for improving wrinkles and other skin conditions
US5993844A (en) * 1997-05-08 1999-11-30 Organogenesis, Inc. Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix
US6143315A (en) * 1997-07-24 2000-11-07 Wang; Ming X. Biochemical contact lens for treating injured corneal tissue
US5932205A (en) * 1997-07-24 1999-08-03 Wang; Ming X. Biochemical contact lens for treating photoablated corneal tissue
US6371992B1 (en) * 1997-12-19 2002-04-16 The Regents Of The University Of California Acellular matrix grafts: preparation and use
US6432710B1 (en) * 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
US6734018B2 (en) * 1999-06-07 2004-05-11 Lifenet Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced
US6312474B1 (en) * 1999-09-15 2001-11-06 Bio-Vascular, Inc. Resorbable implant materials
US6432712B1 (en) * 1999-11-22 2002-08-13 Bioscience Consultants, Llc Transplantable recellularized and reendothelialized vascular tissue graft
US6479064B1 (en) * 1999-12-29 2002-11-12 Children's Medical Center Corporation Culturing different cell populations on a decellularized natural biostructure for organ reconstruction
US6428802B1 (en) * 1999-12-29 2002-08-06 Children's Medical Center Corp. Preparing artificial organs by forming polylayers of different cell populations on a substrate
US6376244B1 (en) * 1999-12-29 2002-04-23 Children's Medical Center Corporation Methods and compositions for organ decellularization
US6866686B2 (en) * 2000-01-28 2005-03-15 Cryolife, Inc. Tissue graft
WO2002014480A2 (fr) * 2000-08-16 2002-02-21 Duke University Constructions de tissu decellularise issues de l'ingenierie tissulaire et tissus ainsi produits
AU9109201A (en) * 2000-09-18 2002-03-26 Organogenesis Inc Methods for treating a patient using a bioengineered flat sheet graft prostheses
WO2003032735A1 (fr) * 2001-10-18 2003-04-24 Lifecell Corporation Remodelage de tissus et d'organes
US7497602B2 (en) 2007-02-08 2009-03-03 Wen-Cheng Lien Three dimension collapsible lampshade

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612028A (en) * 1988-02-17 1997-03-18 Genethics Limited Method of regenerating or replacing cartilage tissue using amniotic cells
US6152142A (en) * 1997-02-28 2000-11-28 Tseng; Scheffer C. G. Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries

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