AU2004247377A1 - Anthranylamide pyridones that inhibit VEGFR-2 and VEGFR-3 - Google Patents
Anthranylamide pyridones that inhibit VEGFR-2 and VEGFR-3 Download PDFInfo
- Publication number
- AU2004247377A1 AU2004247377A1 AU2004247377A AU2004247377A AU2004247377A1 AU 2004247377 A1 AU2004247377 A1 AU 2004247377A1 AU 2004247377 A AU2004247377 A AU 2004247377A AU 2004247377 A AU2004247377 A AU 2004247377A AU 2004247377 A1 AU2004247377 A1 AU 2004247377A1
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- Prior art keywords
- stands
- compounds
- alkyl
- cycloalkyl
- halo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10327719.6 | 2003-06-13 | ||
| DE10327719A DE10327719A1 (de) | 2003-06-13 | 2003-06-13 | VEGFR-2 und VEGFR-3 Inhibitorische Anthranylamidpyridone |
| PCT/EP2004/006236 WO2004111005A1 (fr) | 2003-06-13 | 2004-06-09 | Anthranylamide pyridones qui inhibent vegfr-2 et vegfr-3 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2004247377A1 true AU2004247377A1 (en) | 2004-12-23 |
Family
ID=33520741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004247377A Abandoned AU2004247377A1 (en) | 2003-06-13 | 2004-06-09 | Anthranylamide pyridones that inhibit VEGFR-2 and VEGFR-3 |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1633713A1 (fr) |
| JP (1) | JP2006527228A (fr) |
| KR (1) | KR20060021887A (fr) |
| CN (1) | CN1805936A (fr) |
| AU (1) | AU2004247377A1 (fr) |
| BR (1) | BRPI0411360A (fr) |
| CA (1) | CA2526041A1 (fr) |
| CR (1) | CR8127A (fr) |
| DE (1) | DE10327719A1 (fr) |
| EA (1) | EA200501885A1 (fr) |
| EC (1) | ECSP066280A (fr) |
| IL (1) | IL171898A0 (fr) |
| MX (1) | MXPA05013586A (fr) |
| NO (1) | NO20060196L (fr) |
| RS (1) | RS20050831A (fr) |
| UA (1) | UA81323C2 (fr) |
| WO (1) | WO2004111005A1 (fr) |
| ZA (1) | ZA200600291B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060071812A (ko) * | 2004-12-22 | 2006-06-27 | 주식회사 엘지생명과학 | 신규한 3-(2-아미노-6-피리디닐)-4-히드록시페닐 아민유도체 |
| US9376393B2 (en) * | 2012-01-05 | 2016-06-28 | Clanotech Ab | Quinoline compounds which are anti-angiogenic integrin alpha5 beta1 inhibitors for use in the treatment of fibrosis or fibrosis-related diseases |
| CN106496107A (zh) * | 2016-08-31 | 2017-03-15 | 浙江永宁药业股份有限公司 | Vegfr‑2抑制剂及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9824579D0 (en) * | 1998-11-10 | 1999-01-06 | Novartis Ag | Organic compounds |
| UA71587C2 (uk) * | 1998-11-10 | 2004-12-15 | Шерінг Акцієнгезелльшафт | Аміди антранілової кислоти та їхнє застосування як лікарських засобів |
| DE10023486C1 (de) * | 2000-05-09 | 2002-03-14 | Schering Ag | Ortho substituierte Anthranilsäureamide und deren Verwendung als Arzneimittel |
| WO2002090352A2 (fr) * | 2001-05-08 | 2002-11-14 | Schering Aktiengesellschaft | Anthranylamides pyridine amides selectives en tant qu'inhibateurs vegfr-2 et vegfr-3 |
| GB0126902D0 (en) * | 2001-11-08 | 2002-01-02 | Novartis Ag | Organic compounds |
| DE10228090A1 (de) * | 2002-06-19 | 2004-01-15 | Schering Ag | Ausgewählte Anthranylamidpyridinamide und deren Verwendung als Arzneimittel |
-
2003
- 2003-06-13 DE DE10327719A patent/DE10327719A1/de not_active Ceased
-
2004
- 2004-06-09 EA EA200501885A patent/EA200501885A1/ru unknown
- 2004-06-09 WO PCT/EP2004/006236 patent/WO2004111005A1/fr not_active Ceased
- 2004-06-09 EP EP04739742A patent/EP1633713A1/fr not_active Withdrawn
- 2004-06-09 CN CNA2004800163643A patent/CN1805936A/zh active Pending
- 2004-06-09 CA CA002526041A patent/CA2526041A1/fr not_active Abandoned
- 2004-06-09 BR BRPI0411360-8A patent/BRPI0411360A/pt not_active IP Right Cessation
- 2004-06-09 KR KR1020057023901A patent/KR20060021887A/ko not_active Withdrawn
- 2004-06-09 MX MXPA05013586A patent/MXPA05013586A/es unknown
- 2004-06-09 RS YUP-2005/0831A patent/RS20050831A/sr unknown
- 2004-06-09 AU AU2004247377A patent/AU2004247377A1/en not_active Abandoned
- 2004-06-09 JP JP2006515873A patent/JP2006527228A/ja active Pending
- 2004-09-06 UA UAA200512752A patent/UA81323C2/uk unknown
-
2005
- 2005-11-10 IL IL171898A patent/IL171898A0/en unknown
- 2005-12-09 CR CR8127A patent/CR8127A/es not_active Application Discontinuation
-
2006
- 2006-01-12 EC EC2006006280A patent/ECSP066280A/es unknown
- 2006-01-12 ZA ZA200600291A patent/ZA200600291B/en unknown
- 2006-01-12 NO NO20060196A patent/NO20060196L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2526041A1 (fr) | 2004-12-23 |
| DE10327719A1 (de) | 2005-01-20 |
| EA200501885A1 (ru) | 2006-06-30 |
| MXPA05013586A (es) | 2006-03-09 |
| RS20050831A (sr) | 2008-04-04 |
| WO2004111005A1 (fr) | 2004-12-23 |
| KR20060021887A (ko) | 2006-03-08 |
| JP2006527228A (ja) | 2006-11-30 |
| CR8127A (es) | 2006-05-29 |
| ZA200600291B (en) | 2007-03-28 |
| EP1633713A1 (fr) | 2006-03-15 |
| IL171898A0 (en) | 2006-04-10 |
| NO20060196L (no) | 2006-01-12 |
| BRPI0411360A (pt) | 2006-07-25 |
| UA81323C2 (en) | 2007-12-25 |
| ECSP066280A (es) | 2006-07-28 |
| CN1805936A (zh) | 2006-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |