AU2017285351B2 - PAPD5 and PAPD7 inhibitors for treating a hepatitis B infection - Google Patents

PAPD5 and PAPD7 inhibitors for treating a hepatitis B infection Download PDF

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Publication number
AU2017285351B2
AU2017285351B2 AU2017285351A AU2017285351A AU2017285351B2 AU 2017285351 B2 AU2017285351 B2 AU 2017285351B2 AU 2017285351 A AU2017285351 A AU 2017285351A AU 2017285351 A AU2017285351 A AU 2017285351A AU 2017285351 B2 AU2017285351 B2 AU 2017285351B2
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papd5
papd7
ser
hbv
leu
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AU2017285351A
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AU2017285351A1 (en
Inventor
Xingchun Han
Hassan JAVANBAKHT
Henrik Mueller
Yongguang Wang
Song Yang
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Priority to AU2023202562A priority Critical patent/AU2023202562A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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AU2017285351A 2016-06-17 2017-06-19 PAPD5 and PAPD7 inhibitors for treating a hepatitis B infection Ceased AU2017285351B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2023202562A AU2023202562A1 (en) 2016-06-17 2023-04-27 PAPD5 and PAPD7 inhibitors for treating a hepatitis B infection

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16175045.0 2016-06-17
EP16175045 2016-06-17
PCT/EP2017/064981 WO2017216391A1 (en) 2016-06-17 2017-06-19 Papd5 and papd7 inhibitors for treating a hepatitis b infection

Related Child Applications (1)

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AU2023202562A Division AU2023202562A1 (en) 2016-06-17 2023-04-27 PAPD5 and PAPD7 inhibitors for treating a hepatitis B infection

Publications (2)

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AU2017285351A1 AU2017285351A1 (en) 2018-12-13
AU2017285351B2 true AU2017285351B2 (en) 2023-04-20

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Application Number Title Priority Date Filing Date
AU2017285351A Ceased AU2017285351B2 (en) 2016-06-17 2017-06-19 PAPD5 and PAPD7 inhibitors for treating a hepatitis B infection
AU2017285350A Abandoned AU2017285350A1 (en) 2016-06-17 2017-06-19 Nucleic acid molecules for reduction of PAPD5 or PAPD7 mRNA for treating hepatitis B infection
AU2023202562A Abandoned AU2023202562A1 (en) 2016-06-17 2023-04-27 PAPD5 and PAPD7 inhibitors for treating a hepatitis B infection

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Application Number Title Priority Date Filing Date
AU2017285350A Abandoned AU2017285350A1 (en) 2016-06-17 2017-06-19 Nucleic acid molecules for reduction of PAPD5 or PAPD7 mRNA for treating hepatitis B infection
AU2023202562A Abandoned AU2023202562A1 (en) 2016-06-17 2023-04-27 PAPD5 and PAPD7 inhibitors for treating a hepatitis B infection

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US (4) US11191775B2 (pl)
EP (3) EP4219767A1 (pl)
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US20220096527A1 (en) 2022-03-31
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AU2023202562A1 (en) 2023-05-18
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PL3472346T3 (pl) 2023-05-22
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WO2017216391A1 (en) 2017-12-21
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