AU2900599A - Thrombin preparation and products and fibrin sealant methods employing same - Google Patents

Thrombin preparation and products and fibrin sealant methods employing same Download PDF

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Publication number
AU2900599A
AU2900599A AU29005/99A AU2900599A AU2900599A AU 2900599 A AU2900599 A AU 2900599A AU 29005/99 A AU29005/99 A AU 29005/99A AU 2900599 A AU2900599 A AU 2900599A AU 2900599 A AU2900599 A AU 2900599A
Authority
AU
Australia
Prior art keywords
thrombin
prothrombin
fibrinogen
precipitate
plasma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
AU29005/99A
Other languages
English (en)
Inventor
David H. Sierra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Publication of AU2900599A publication Critical patent/AU2900599A/en
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AU29005/99A 1998-03-10 1999-03-10 Thrombin preparation and products and fibrin sealant methods employing same Withdrawn AU2900599A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7761998P 1998-03-10 1998-03-10
US60077619 1998-03-10
PCT/US1999/005034 WO1999045938A1 (fr) 1998-03-10 1999-03-10 Elaboration de thrombine, produits a base de fibrine et procedes de fabrication de materiaux d'obturation a base de fibrine au moyen desdits produits

Publications (1)

Publication Number Publication Date
AU2900599A true AU2900599A (en) 1999-09-27

Family

ID=22139138

Family Applications (1)

Application Number Title Priority Date Filing Date
AU29005/99A Withdrawn AU2900599A (en) 1998-03-10 1999-03-10 Thrombin preparation and products and fibrin sealant methods employing same

Country Status (5)

Country Link
EP (1) EP1061931A2 (fr)
JP (1) JP2002506038A (fr)
AU (1) AU2900599A (fr)
CA (1) CA2322741A1 (fr)
WO (1) WO1999045938A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112997967A (zh) * 2021-03-09 2021-06-22 复旦大学附属华山医院 一种凝血酶磁珠及其制备方法
CN116463323A (zh) * 2023-03-16 2023-07-21 同路生物制药有限公司 一种从组分ⅰ+ⅲ沉淀中制备人凝血酶工艺

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000062828A1 (fr) 1996-04-30 2000-10-26 Medtronic, Inc. Fibrine autologue d'obturation et ses methodes de fabrication
US6274090B1 (en) 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
US6472162B1 (en) 1999-06-04 2002-10-29 Thermogenesis Corp. Method for preparing thrombin for use in a biological glue
EP1239894B1 (fr) * 1999-12-22 2005-03-09 Henogen S.A. Produit pour generer des os
CN102014973A (zh) 2008-02-29 2011-04-13 弗罗桑医疗设备公司 用于促进止血和/或伤口愈合的装置
DE102011112955A1 (de) 2011-09-13 2013-03-14 Medizinische Hochschule Hannover Verfahren zur Herstellung eines biologischen Gewebekonstrukts und Verwendung spezifisch gewonnener autologer Zellen
WO2013131520A2 (fr) 2012-03-06 2013-09-12 Ferrosan Medical Devices A/S Récipient mis sous pression contenant de la pâte hémostatique
RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
WO2014052496A1 (fr) * 2012-09-25 2014-04-03 Stem Cell Partners Llc Procédé et appareil pour préparer le sérum de thrombine d'un donneur individuel
EP3010419B1 (fr) 2013-06-21 2020-05-20 Ferrosan Medical Devices A/S Composition sèche dilatée sous vide, et seringue pour la retenir
JP6489485B2 (ja) 2013-12-11 2019-03-27 フェロサン メディカル デバイシーズ エイ／エス 押し出し増強因子を含んでいる乾燥組成物
CA2960309A1 (fr) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Composition seche destinee a etre utilisee en hemostase et cicatrisation de plaie
RU2705905C2 (ru) 2014-12-24 2019-11-12 Ферросан Медикал Дивайсиз А/С Шприц для удерживания и смешивания первого и второго веществ
AU2016290433B2 (en) 2015-07-03 2018-05-24 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
ES2968412T3 (es) 2018-05-09 2024-05-09 Ferrosan Medical Devices As Método para preparar una composición hemostática
WO2020178419A1 (fr) * 2019-03-06 2020-09-10 Gambro Lundia Ab Dispositif et procédé de distribution d'un agent d'étanchéité à base de fibrine activé par la thrombine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5226877A (en) * 1989-06-23 1993-07-13 Epstein Gordon H Method and apparatus for preparing fibrinogen adhesive from whole blood
JP3404038B2 (ja) * 1991-12-31 2003-05-06 ザイモジェネティクス，インコーポレイティド トロンビンの製造方法
US5266462A (en) * 1992-06-03 1993-11-30 Baxter Diagnostics Inc. Measurement of platelet activities
US5219995A (en) * 1992-07-14 1993-06-15 Alpha Therapeutic Corporation Plasma fraction purification
US5330974A (en) * 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112997967A (zh) * 2021-03-09 2021-06-22 复旦大学附属华山医院 一种凝血酶磁珠及其制备方法
CN116463323A (zh) * 2023-03-16 2023-07-21 同路生物制药有限公司 一种从组分ⅰ+ⅲ沉淀中制备人凝血酶工艺

Also Published As

Publication number Publication date
EP1061931A2 (fr) 2000-12-27
JP2002506038A (ja) 2002-02-26
WO1999045938A1 (fr) 1999-09-16
CA2322741A1 (fr) 1999-09-16
WO1999045938B1 (fr) 1999-12-02

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Legal Events

Date Code Title Description
MK12 Application lapsed section 141(1)/reg 8.3(2) - applicant filed a written notice of withdrawal