AU505351B2 - 1-[[5-(substituted phenyl)-2-oxazoly] -methylene]-amino]-2,4-imidazolidinediones - Google Patents

1-[[5-(substituted phenyl)-2-oxazoly] -methylene]-amino]-2,4-imidazolidinediones

Info

Publication number
AU505351B2
AU505351B2 AU28036/77A AU2803677A AU505351B2 AU 505351 B2 AU505351 B2 AU 505351B2 AU 28036/77 A AU28036/77 A AU 28036/77A AU 2803677 A AU2803677 A AU 2803677A AU 505351 B2 AU505351 B2 AU 505351B2
Authority
AU
Australia
Prior art keywords
mixture
stirred
mole
solid
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU28036/77A
Other languages
English (en)
Other versions
AU2803677A (en
Inventor
R. L. White Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Chilcott Pharmaceuticals Inc
Original Assignee
Morton Norwich Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morton Norwich Products Inc filed Critical Morton Norwich Products Inc
Publication of AU2803677A publication Critical patent/AU2803677A/en
Application granted granted Critical
Publication of AU505351B2 publication Critical patent/AU505351B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU28036/77A 1976-10-18 1977-08-19 1-[[5-(substituted phenyl)-2-oxazoly] -methylene]-amino]-2,4-imidazolidinediones Expired AU505351B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/733,296 US4049650A (en) 1976-10-18 1976-10-18 1-[[[5-(Substituted phenyl)-2-oxazolyl]methylene]amino]-2,4-imidazolidinediones
USUS733,296 1976-10-18

Publications (2)

Publication Number Publication Date
AU2803677A AU2803677A (en) 1979-02-22
AU505351B2 true AU505351B2 (en) 1979-11-15

Family

ID=24947035

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28036/77A Expired AU505351B2 (en) 1976-10-18 1977-08-19 1-[[5-(substituted phenyl)-2-oxazoly] -methylene]-amino]-2,4-imidazolidinediones

Country Status (14)

Country Link
US (1) US4049650A (2)
JP (1) JPS5350167A (2)
AU (1) AU505351B2 (2)
BE (1) BE859819A (2)
CA (1) CA1084510A (2)
CH (1) CH629800A5 (2)
DE (1) DE2746550A1 (2)
ES (1) ES463297A1 (2)
FR (1) FR2367763A1 (2)
GB (1) GB1530770A (2)
MX (1) MX5011E (2)
NL (1) NL7711416A (2)
SE (1) SE435382B (2)
ZA (1) ZA775228B (2)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2657559A1 (de) * 1976-12-18 1978-06-22 Bayer Ag Dioxopiperazinderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel und als zwischenprodukte fuer beta-lactamantibiotika
US4128711A (en) * 1977-10-06 1978-12-05 Morton-Norwich Products, Inc. 1-[[1H-Pyrrol-2-ylmethylene]amino]-2,4-imidazolidinedione
US4822629A (en) * 1986-12-12 1989-04-18 Norwich Eaton Pharmaceuticals, Inc. Azumolene dosage form
US4861790A (en) * 1987-10-28 1989-08-29 Norwich Eaton Pharmaceuticals, Inc. Use of azumolene for the treatment of malignant hyperthermia
WO2007145203A1 (ja) * 2006-06-13 2007-12-21 Daiichi Fine Chemical Co., Ltd. 光学活性２－アミノ－１－（４－フルオロフェニル）エタノール
WO2011040496A1 (ja) 2009-09-30 2011-04-07 株式会社資生堂 ヘパラナーゼ活性阻害剤
HUP1300720A2 (hu) * 2013-12-12 2015-06-29 Univ Szegedi Gyógyászati készítmények sebgyógyulás elõsegítésére

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3415821A (en) * 1965-09-07 1968-12-10 Norwich Pharma Co 1-(5-substituted)furfurylideneamino hydantoins and imidazolidinones
DE2106298A1 (2) * 1971-02-10 1972-10-12
US3803136A (en) * 1972-08-23 1974-04-09 Morton Norwich Products Inc 5-hydroxy-1-((5-(substituted phenyl)furfurylidene)amino)hydrantoins
US3843636A (en) * 1974-01-25 1974-10-22 Morton Norwich Products Inc 1-(5-(p-methoxyphenyl)furfurylidene)amino)hydantoin
US4001222A (en) * 1975-10-14 1977-01-04 Morton-Norwich Products, Inc. 3-(Aminoacyl)-1-{[5-(substituted phenyl)furfurylidene]amino}hydantoins and process for their preparation thereof

Also Published As

Publication number Publication date
US4049650A (en) 1977-09-20
CH629800A5 (de) 1982-05-14
GB1530770A (en) 1978-11-01
SE435382B (sv) 1984-09-24
BE859819A (fr) 1978-04-17
ES463297A1 (es) 1978-11-16
JPS5350167A (en) 1978-05-08
MX5011E (es) 1983-02-16
FR2367763A1 (fr) 1978-05-12
JPS6225148B2 (2) 1987-06-01
SE7710086L (sv) 1978-04-19
CA1084510A (en) 1980-08-26
FR2367763B1 (2) 1980-06-27
DE2746550C2 (2) 1987-10-15
NL7711416A (nl) 1978-04-20
DE2746550A1 (de) 1978-04-20
ZA775228B (en) 1979-04-25
AU2803677A (en) 1979-02-22

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