AU684730B2 - Octahydrobenzo{f}quinoline-based receptor agonists and antagonists - Google Patents

Octahydrobenzo{f}quinoline-based receptor agonists and antagonists

Info

Publication number: AU684730B2
Authority: AU; Australia
Prior art keywords: trans; quinoline; octahydrobenzo; phenethyl; cis
Prior art date: 1993-11-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

AU56153/94A

Other languages

English (en)

Other versions

AU5615394A (en

Inventor

Mark Froimowitz

James N Jacob

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Rhode Island Board of Education

Original Assignee

Rhode Island Board of Education

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-19

Filing date

1993-11-19

Publication date

1998-01-08

1993-11-19 Application filed by Rhode Island Board of Education filed Critical Rhode Island Board of Education

1995-06-06 Publication of AU5615394A publication Critical patent/AU5615394A/en

1998-01-08 Application granted granted Critical

1998-01-08 Publication of AU684730B2 publication Critical patent/AU684730B2/en

2013-11-19 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

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239000000018 receptor agonist Substances 0.000 title description 4
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AU56153/94A 1993-11-19 1993-11-19 Octahydrobenzo{f}quinoline-based receptor agonists and antagonists Ceased AU684730B2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US1993/011302 WO1995014006A1 (en)	1993-11-19	1993-11-19	OCTAHYDROBENZO[f]QUINOLINE-BASED RECEPTOR AGONISTS AND ANTAGONISTS

Publications (2)

Publication Number	Publication Date
AU5615394A AU5615394A (en)	1995-06-06
AU684730B2 true AU684730B2 (en)	1998-01-08

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ID=22237207

Family Applications (1)

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AU56153/94A Ceased AU684730B2 (en)	1993-11-19	1993-11-19	Octahydrobenzo{f}quinoline-based receptor agonists and antagonists

Country Status (5)

Country	Link
EP (1)	EP0729458A1 (de)
JP (1)	JPH09509398A (de)
AU (1)	AU684730B2 (de)
CA (1)	CA2177046A1 (de)
WO (1)	WO1995014006A1 (de)

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Publication number	Priority date	Publication date	Assignee	Title
US5688950A (en) *	1996-04-23	1997-11-18	Neurogen Corporation	Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands
GB9612153D0 (en) *	1996-06-11	1996-08-14	Smithkline Beecham Plc	Compounds
UA73981C2 (en) *	2000-03-10	2005-10-17	Merck Patent Gmbh	(r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
EP2401255A1 (de) *	2009-02-25	2012-01-04	H. Lundbeck A/S	Catecholaminderivate und prodrugs davon

Citations (1)

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Publication number	Priority date	Publication date	Assignee	Title
WO1984004303A1 (en) *	1983-04-27	1984-11-08	Astra Laekemedel Ab	NEW OCTAHYDROBENZO (f) QUINOLINE DERIVATIVES

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Publication number	Priority date	Publication date	Assignee	Title
US4341786A (en) *	1981-03-02	1982-07-27	Smithkline Corporation	Pharmaceutical compositions and method of producing central alpha1 agonist activity utilizing octahydrobenzo[f]quinoline compounds

1993
- 1993-11-19 EP EP94901631A patent/EP0729458A1/de not_active Withdrawn
- 1993-11-19 AU AU56153/94A patent/AU684730B2/en not_active Ceased
- 1993-11-19 JP JP7514411A patent/JPH09509398A/ja active Pending
- 1993-11-19 WO PCT/US1993/011302 patent/WO1995014006A1/en not_active Ceased
- 1993-11-19 CA CA002177046A patent/CA2177046A1/en not_active Abandoned

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1984004303A1 (en) *	1983-04-27	1984-11-08	Astra Laekemedel Ab	NEW OCTAHYDROBENZO (f) QUINOLINE DERIVATIVES

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
J. MED. CHEM, 1979, 22, PP341-347 *
J. MED. CHEM, 1982, 25, PP925-931 *

Also Published As

Publication number	Publication date
WO1995014006A1 (en)	1995-05-26
JPH09509398A (ja)	1997-09-22
EP0729458A1 (de)	1996-09-04
AU5615394A (en)	1995-06-06
CA2177046A1 (en)	1995-05-26

Legal Events

Date	Code	Title	Description
2003-06-26	MK14	Patent ceased section 143(a) (annual fees not paid) or expired

Publication	Publication Date	Title
US5354758A (en)	1994-10-11	Benzomorphans useful as NMDA receptor antagonists
AU6112596A (en)	1996-12-30	Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders
EP1096926B1 (de)	2007-02-28	Verfahren und verbindungen zur behandlung der depression
JPH06502165A (ja)	1994-03-10	治療上有用な２−アミノテトラリン誘導体
LT3966B (en)	1996-05-27	Novel 8-substituted-2-aminotetralines, process for preparing thereof, pharmaceutical composition
JPH0780855B2 (ja)	1995-08-30	新規化合物、その製造方法及びそれを含む医薬組成物
DK144094B (da)	1981-12-07	Analogifremgangsmaade til fremstilling af n-substituerede 3-hydroxy-8-oxamorphianer eller syreadditionssalte deraf
AU684730B2 (en)	1998-01-08	Octahydrobenzo{f}quinoline-based receptor agonists and antagonists
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