AU746190B2 - Heart and skeleton muscle specific nucleic acid, the production and use thereof - Google Patents

Heart and skeleton muscle specific nucleic acid, the production and use thereof Download PDF

Info

Publication number
AU746190B2
AU746190B2 AU84385/98A AU8438598A AU746190B2 AU 746190 B2 AU746190 B2 AU 746190B2 AU 84385/98 A AU84385/98 A AU 84385/98A AU 8438598 A AU8438598 A AU 8438598A AU 746190 B2 AU746190 B2 AU 746190B2
Authority
AU
Australia
Prior art keywords
polypeptide
nucleic acid
sequence
parts
functional variant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU84385/98A
Other languages
English (en)
Other versions
AU8438598A (en
Inventor
Horst Domdey
Thomas Henkel
Marion Elke Hofmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medigene AG
Original Assignee
Medigene AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medigene AG filed Critical Medigene AG
Publication of AU8438598A publication Critical patent/AU8438598A/en
Application granted granted Critical
Publication of AU746190B2 publication Critical patent/AU746190B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU84385/98A 1997-06-13 1998-06-15 Heart and skeleton muscle specific nucleic acid, the production and use thereof Ceased AU746190B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19725186 1997-06-13
DE19725186A DE19725186C2 (de) 1997-06-13 1997-06-13 Herz- und Skelettmuskel-spezifische Nukleinsäure, ihre Herstellung und Verwendung
PCT/EP1998/003584 WO1998056907A1 (de) 1997-06-13 1998-06-15 Herz- und skelettmuskel-spezifische nukleinsäure, ihre herstellung und verwendung

Publications (2)

Publication Number Publication Date
AU8438598A AU8438598A (en) 1998-12-30
AU746190B2 true AU746190B2 (en) 2002-04-18

Family

ID=7832477

Family Applications (1)

Application Number Title Priority Date Filing Date
AU84385/98A Ceased AU746190B2 (en) 1997-06-13 1998-06-15 Heart and skeleton muscle specific nucleic acid, the production and use thereof

Country Status (6)

Country Link
EP (1) EP1000145A1 (de)
JP (1) JP2002509433A (de)
AU (1) AU746190B2 (de)
CA (1) CA2293733A1 (de)
DE (1) DE19725186C2 (de)
WO (1) WO1998056907A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962154A1 (de) * 1999-12-22 2001-07-12 Medigene Ag Krankhaft veränderte Herzmuskelzelle, ihre Herstellung und Verwendung
CA2410949A1 (en) * 2000-05-30 2001-12-06 Medigene Ag Novel target genes for diseases of the heart
AU2003205611A1 (en) * 2002-01-15 2003-07-30 Medigene Ag Dilated cardiomyopathy associated gene-2 (dcmag-2): a cytoplasmatic inducer of sarcomeric remodeling in cardiomyocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283173A (en) * 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions
EP0862644A2 (de) * 1995-11-17 1998-09-09 Franz, Wolfgang-M., Dr. Gentherapeutisches nukleinsäurekonstrukt, seine herstellung und verwendung zur behandlung von herzerkrankungen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. BIOL. CHEMISTRY, 269, PP 27510-27518 (1994) *

Also Published As

Publication number Publication date
EP1000145A1 (de) 2000-05-17
WO1998056907A1 (de) 1998-12-17
DE19725186C2 (de) 2000-06-15
JP2002509433A (ja) 2002-03-26
AU8438598A (en) 1998-12-30
DE19725186A1 (de) 1998-12-24
CA2293733A1 (en) 1998-12-17

Similar Documents

Publication Publication Date Title
US6090618A (en) DNA constructs and viral vectors comprising a smooth muscle promoter
US6300484B1 (en) DNA encoding DP. 75 and a process for its use
CN113613668A (zh) 小型化肌营养不良蛋白及其用途
JP2002541829A (ja) 遺伝子治療および治療的スクリーニングに有用なｅＮＯＳ変異体
US20030175260A1 (en) Novel DNA and a process for its use
CA2281674A1 (en) Parg, a gtpase activating protein which interacts with ptpl1
CA2293733A1 (en) Mycardium-and skeletal muscle-specific nucleic acid, its preparation and use
JPH1169985A (ja) 慢性腎不全の標的およびマーカーであるＣＲＦＧ−１ａ
JPH10504714A (ja) ヒトカリウムチャンネル１および２タンパク質
JPH10304883A (ja) 新規化合物
AU2476301A (en) DB the receptor for leptin nucleic acids encoding the receptor, and uses thereof
JPH10512145A (ja) ヒトゲラニルゲラニルピロリン酸シンセターゼ
US6653446B2 (en) Human hypoxanthine- (guanine) phosphoribosyl transferase-2
US7041497B2 (en) Nuclear factor κB inducing factor
JPH10327881A (ja) 分泌マウスタンパク質ｓＦＲＰ−１に類似した新規ヒト 遺伝子
JPH114698A (ja) 分泌性タンパク質Ｆｒｉｚｂと類似する新規ヒト遺伝子（ＡＴＧ−１６３９）
JPH11502119A (ja) ヒトｂ細胞転座遺伝子−２及び３
JPH11164693A (ja) 慢性腎不全、アテローム性動脈硬化および繊維症の標的 としての新規なｓＭＡＤ３スプライス変異体
US6998475B1 (en) Variants of traf2 which act as an inhibitor of tnf-alpha (tnfα) signaling pathway
JP2002330793A (ja) 重炭酸ナトリウム共輸送体ファミリーのメンバーであるｈｎｂｃ１ａ
JP2000508057A (ja) 骨抗ウイルスタンパク質
JPH1132785A (ja) 慢性腎不全の標的およびマーカーであるｃｒｆｇ−１
JPH1175865A (ja) 分泌ネズミ・蛋白ｓｄｆ５に類似したヒト・遺伝子（ａｔｇ−１６２２）
JPH11505110A (ja) ヒトニューロペプチドレセプター
WO2001038382A1 (fr) Nouveau polypeptide, ou proteine 54 humaine associee a l'actine, et polynucleotide codant pour ledit polypeptide

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)