AU7665196A - Oxazolidinone antibacterial agent with tricyclic substituents - Google Patents

Oxazolidinone antibacterial agent with tricyclic substituents

Info

Publication number: AU7665196A
Authority: AU; Australia
Prior art keywords: antibacterial agent; oxazolidinone antibacterial; organisms; tricyclic substituents; tricyclic
Prior art date: 1995-11-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU76651/96A

Other languages

English (en)

Inventor

Gary J Cleek

Douglas K Hutchinson

Richard C. Thomas

Hiroyoshi Yamada

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pharmacia and Upjohn Co

Original Assignee

Pharmacia and Upjohn Co

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-17

Filing date

1996-11-05

Publication date

1997-06-11

1996-11-05 Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co

1997-06-11 Publication of AU7665196A publication Critical patent/AU7665196A/en

Status Abandoned legal-status Critical Current

Links

IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
239000003242 anti bacterial agent Substances 0.000 title 1
241000186367 Mycobacterium avium Species 0.000 abstract 2
241000606125 Bacteroides Species 0.000 abstract 1
241001112696 Clostridia Species 0.000 abstract 1
241000295644 Staphylococcaceae Species 0.000 abstract 1
241001148470 aerobic bacillus Species 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
244000052769 pathogen Species 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AU76651/96A 1995-11-17 1996-11-05 Oxazolidinone antibacterial agent with tricyclic substituents Abandoned AU7665196A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US737195P	1995-11-17	1995-11-17
US007371		1995-11-17
PCT/US1996/017120 WO1997019089A1 (en)	1995-11-17	1996-11-05	Oxazolidinone antibacterial agent with tricyclic substituents

Publications (1)

Publication Number	Publication Date
AU7665196A true AU7665196A (en)	1997-06-11

Family

ID=21725778

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU76651/96A Abandoned AU7665196A (en)	1995-11-17	1996-11-05	Oxazolidinone antibacterial agent with tricyclic substituents

Country Status (12)

Country	Link
US (2)	US5922707A (2)
EP (1)	EP0874852B1 (2)
JP (1)	JP2000500489A (2)
AT (1)	ATE263172T1 (2)
AU (1)	AU7665196A (2)
DE (1)	DE69632074T2 (2)
DK (1)	DK0874852T3 (2)
ES (1)	ES2217329T3 (2)
PT (1)	PT874852E (2)
TW (1)	TW426683B (2)
WO (1)	WO1997019089A1 (2)
ZA (1)	ZA968661B (2)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA968661B (en) *	1995-11-17	1998-04-14	Upjohn Co	Oxazolidinone antibacterial agent with tricyclic substituents.
GB9601666D0 (en) *	1996-01-27	1996-03-27	Zeneca Ltd	Chemical compounds
GB9702213D0 (en)	1996-02-24	1997-03-26	Zeneca Ltd	Chemical compounds
GB9609919D0 (en)	1996-05-11	1996-07-17	Zeneca Ltd	Chemical compounds
AU8457298A (en) *	1997-08-15	1999-03-08	Pfizer Products Inc.	2-(4-aryl or heteroaryl-piperazin-1-ylmethyl)-1H-indole derivatives interacting with the dopamine D4 receptor
GB9717804D0 (en)	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9717807D0 (en)	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9725244D0 (en)	1997-11-29	1998-01-28	Zeneca Ltd	Chemical compounds
DE19802239A1 (de) *	1998-01-22	1999-07-29	Bayer Ag	Neue mit Bicyclen substituierte Oxazolidinone
DE19802235A1 (de) *	1998-01-22	1999-07-29	Bayer Ag	Mit tricyclischen Indolen substituierte Oxazolidinone
US7002020B1 (en)	1998-01-23	2006-02-21	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en)	1998-01-23	2003-05-13	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
WO1999037630A1 (en)	1998-01-23	1999-07-29	Versicor, Inc.	Oxazolidinone combinatorial libraries, compositions and methods of preparation
DE19805117A1 (de) *	1998-02-09	1999-08-12	Bayer Ag	Neue Oxazolidinone mit azolhaltigen Tricyclen
KR20010052615A (ko)	1998-06-05	2001-06-25	다비드 에 질레스	옥사졸리디논 유도체, 이것의 제조 방법 및 이것을함유하는 약학 조성물
MY122454A (en) *	1998-06-05	2006-04-29	Upjohn Co	Use of oxazolidinones for the preparation of a medicament for transdermal delivery
PL346795A1 (en)	1998-09-22	2002-02-25	Yamanouchi Pharma Co Ltd	Cyanophenyl derivatives
EP1147422A1 (en)	1999-01-27	2001-10-24	Pharmacia & Upjohn Company	Assays for modulators of "elongation factor p" activity
JP2003501351A (ja) *	1999-05-27	2003-01-14	ファルマシア・アンド・アップジョン・カンパニー	抗菌剤としての二環系オキサゾリジノン
GB9928568D0 (en)	1999-12-03	2000-02-02	Zeneca Ltd	Chemical compounds
GB0009803D0 (en) *	2000-04-25	2000-06-07	Astrazeneca Ab	Chemical compounds
WO2004014897A1 (en)	2002-08-12	2004-02-19	Pharmacia & Upjohn Company Llc	N-aryl-2-oxazolidinones and their derivatives
WO2004045616A1 (en)	2002-11-21	2004-06-03	Pharmacia & Upjohn Company Llc	N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinone-5-carboxamide derivates and related compounds as antibacterial agents
EP1594865A2 (en) *	2003-02-07	2005-11-16	Warner-Lambert Company LLC	Antibacterial agents
EP1661898A4 (en) *	2003-08-29	2009-04-15	Takeda Pharmaceutical	BICYCLIC PIPERAZINE COMPOUND AND ITS USE
AR057828A1 (es) *	2005-09-29	2007-12-19	Astrazeneca Ab	Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
WO2007087250A2 (en) *	2006-01-23	2007-08-02	Amira Pharmaceuticals, Inc.	Tricyclic inhibitors of 5-lipoxygenase
CN113603707B (zh) *	2016-12-12	2023-03-31	石药集团中奇制药技术（石家庄）有限公司	一类含有三环杂芳基的化合物
CN114644634B (zh) *	2020-12-21	2023-06-20	深圳市祥根生物医药有限公司	一种吡咯衍生物及其制备方法和用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3883522A (en) *	1974-02-11	1975-05-13	Riker Laboratories Inc	Substituted pyrido(1,2,3-de)-1,4-benzoxazines
US4080499A (en) *	1976-12-20	1978-03-21	1	Substituted 7,8-dihydro-6H-(1,2,5)thiadiazolo(3',4'-5,6)pyrazino(2,3-b)(1,4)oxazines
US5039690A (en) *	1987-10-09	1991-08-13	Du Pont Merck Pharmaceutical Company	Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
ATE112773T1 (de) *	1988-09-15	1994-10-15	Upjohn Co	5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one.
US5225565A (en) *	1988-09-15	1993-07-06	The Upjohn Company	Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
ES2177539T3 (es) *	1992-02-13	2002-12-16	Upjohn Co	Benzoxacinas 4-oxo- y 4h-imidazo(5,1-c)(1,4) utilez como agentes de union de receptores de benzodiacepina.
SK283420B6 (sk) *	1992-05-08	2003-07-01	Pharmacia & Upjohn Company	Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5668286A (en) *	1994-03-15	1997-09-16	Pharmacia & Upjohn Company	Oxazolidinone derivatives and pharmaceutical compositions containing them
BR9509673A (pt) *	1994-11-15	1997-09-30	Upjohn Co	Compostos e uso dos mesmos
ZA968661B (en) *	1995-11-17	1998-04-14	Upjohn Co	Oxazolidinone antibacterial agent with tricyclic substituents.

1996
- 1996-10-14 ZA ZA9608661A patent/ZA968661B/xx unknown
- 1996-11-05 ES ES96939496T patent/ES2217329T3/es not_active Expired - Lifetime
- 1996-11-05 AU AU76651/96A patent/AU7665196A/en not_active Abandoned
- 1996-11-05 EP EP96939496A patent/EP0874852B1/en not_active Expired - Lifetime
- 1996-11-05 WO PCT/US1996/017120 patent/WO1997019089A1/en not_active Ceased
- 1996-11-05 DK DK96939496T patent/DK0874852T3/da active
- 1996-11-05 PT PT96939496T patent/PT874852E/pt unknown
- 1996-11-05 DE DE69632074T patent/DE69632074T2/de not_active Expired - Fee Related
- 1996-11-05 AT AT96939496T patent/ATE263172T1/de not_active IP Right Cessation
- 1996-11-05 JP JP9519726A patent/JP2000500489A/ja not_active Withdrawn
- 1996-11-15 TW TW085114048A patent/TW426683B/zh not_active IP Right Cessation
1997
- 1997-05-02 US US08/850,424 patent/US5922707A/en not_active Expired - Fee Related
1999
- 1999-02-15 US US09/250,382 patent/US5955460A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0874852B1 (en)	2004-03-31
ZA968661B (en)	1998-04-14
JP2000500489A (ja)	2000-01-18
EP0874852A1 (en)	1998-11-04
WO1997019089A1 (en)	1997-05-29
PT874852E (pt)	2004-08-31
TW426683B (en)	2001-03-21
DE69632074T2 (de)	2005-01-20
US5922707A (en)	1999-07-13
DK0874852T3 (da)	2004-06-07
US5955460A (en)	1999-09-21
DE69632074D1 (de)	2004-05-06
ATE263172T1 (de)	2004-04-15
ES2217329T3 (es)	2004-11-01

Publication	Publication Date	Title
ZA968661B (en)	1998-04-14	Oxazolidinone antibacterial agent with tricyclic substituents.
MX9703543A (es)	1997-08-30	Antibacterianos de oxazina biciclica y oxazolidinona tiazina.
PL319873A1 (en)	1997-09-01	Antibacterial phenyloxazolydinones
LV12605A (en)	2001-01-20	Substituted oxazine and thiazine oxazlidinone antimicrobials
AU6964096A (en)	1997-04-01	Aminoaryl oxazolidinone n-oxides
CA2236677A1 (en)	1997-06-19	4-pyrimidinyl- or 4-pyrazinyl-piperazinyl-phenyl-oxazolidinone derivatives, their preparation and their use as anti-bacterial agents
EP1409464A4 (en)	2005-11-02	OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS
MX9703040A (es)	1997-07-31	Antimicrobianos de feniloxazolidinona.
HUT50345A (en)	1990-01-29	Process for production of cefem-derivatives and their intermediers