BE1000167A4 - Antigene du virus de l'hepatite b et procede pour sa production. - Google Patents

Antigene du virus de l'hepatite b et procede pour sa production. Download PDF

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Publication number
BE1000167A4
BE1000167A4 BE8700666A BE8700666A BE1000167A4 BE 1000167 A4 BE1000167 A4 BE 1000167A4 BE 8700666 A BE8700666 A BE 8700666A BE 8700666 A BE8700666 A BE 8700666A BE 1000167 A4 BE1000167 A4 BE 1000167A4
Authority
BE
Belgium
Prior art keywords
hepatitis
production
antigen
virus antigen
virus
Prior art date
Application number
BE8700666A
Other languages
English (en)
Original Assignee
Univ Osaka Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Osaka Res Found filed Critical Univ Osaka Res Found
Application granted granted Critical
Publication of BE1000167A4 publication Critical patent/BE1000167A4/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/94—Saccharomyces
    • Y10S435/942—Saccharomyces cerevisiae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Une séquence d'acides aminés de l'antigène de surface de ce virus; le présent antigène peut etre produit facilement en toute sécurité à faible prix par technique d'ADN recombinant, il peut etre utilisé comme vaccin efficace et diagnostic de l'hépatite B; le dessin joint montre un organigramme indiquant le clonage de l'ADN de l'antigène du virus de l'hépatite B et la préparation du plasmide pM1B11.
BE8700666A 1986-06-18 1987-06-17 Antigene du virus de l'hepatite b et procede pour sa production. BE1000167A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61143412A JPH089637B2 (ja) 1986-06-18 1986-06-18 Ｂ型肝炎ウイルス抗原とその製造法

Publications (1)

Publication Number Publication Date
BE1000167A4 true BE1000167A4 (fr) 1988-07-05

Family

ID=15338168

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8700666A BE1000167A4 (fr) 1986-06-18 1987-06-17 Antigene du virus de l'hepatite b et procede pour sa production.

Country Status (5)

Country Link
US (1) US5693497A (fr)
JP (1) JPH089637B2 (fr)
BE (1) BE1000167A4 (fr)
CA (1) CA1340521C (fr)
FR (1) FR2606281B1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993012815A1 (fr) * 1991-12-27 1993-07-08 Gensci Limited Procede d'obtention d'un antigene de surface recombine de l'hepatite b, antigene et vaccin a base de celui-ci
US20030009013A1 (en) * 1998-12-30 2003-01-09 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2000270876A (ja) * 1999-03-26 2000-10-03 Genome Science Laboratories Co Ltd Ｂ型肝炎ウイルス遺伝子の変異検出方法および検出キット
KR100423614B1 (ko) * 2001-05-16 2004-03-22 주식회사유한양행 비형간염바이러스의 에스-표면항원을 인식하는단일클론항체의 가변영역 및 이를 코딩하는 유전자
JP4430677B2 (ja) * 2004-09-22 2010-03-10 株式会社先端生命科学研究所 Ｂ型肝炎ウイルスｓ抗原の検出法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0020251A2 (fr) * 1979-05-24 1980-12-10 The Regents Of The University Of California Vecteur de transfert d'ADN, hôte transformé par celui-ci, vaccin, et leur production
EP0105149A2 (fr) * 1982-08-16 1984-04-11 Science and Technology Agency, Minister's Secretariat, Director of Finance Division Plasmide recombinant contenant le gène du virus de l'hépatite B, levure transformée avec ce plasmide recombinant et production de l'antigène de surface du virus de l'hépatite B
EP0171908A2 (fr) * 1984-07-11 1986-02-19 Takeda Chemical Industries, Ltd. Antigène de surface du virus de l'hépatite B et production
EP0174444A2 (fr) * 1984-06-18 1986-03-19 Chiron Corporation Vaccin à base de particule d'antigène de surface de l'hépatite
EP0182442A2 (fr) * 1978-12-22 1986-05-28 Biogen, Inc. Molécules de l'ADN recombinant et procédé pour leur production

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935235A (en) * 1979-05-24 1990-06-19 The Regents Of The University Of California Non-passageable viruses
GR76274B (fr) * 1981-08-04 1984-08-04 Univ California
JPS5974985A (ja) * 1982-10-19 1984-04-27 Takeda Chem Ind Ltd 新規ｄｎａ
US4722840A (en) * 1984-09-12 1988-02-02 Chiron Corporation Hybrid particle immunogens

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0182442A2 (fr) * 1978-12-22 1986-05-28 Biogen, Inc. Molécules de l'ADN recombinant et procédé pour leur production
EP0020251A2 (fr) * 1979-05-24 1980-12-10 The Regents Of The University Of California Vecteur de transfert d'ADN, hôte transformé par celui-ci, vaccin, et leur production
EP0105149A2 (fr) * 1982-08-16 1984-04-11 Science and Technology Agency, Minister's Secretariat, Director of Finance Division Plasmide recombinant contenant le gène du virus de l'hépatite B, levure transformée avec ce plasmide recombinant et production de l'antigène de surface du virus de l'hépatite B
EP0174444A2 (fr) * 1984-06-18 1986-03-19 Chiron Corporation Vaccin à base de particule d'antigène de surface de l'hépatite
EP0171908A2 (fr) * 1984-07-11 1986-02-19 Takeda Chemical Industries, Ltd. Antigène de surface du virus de l'hépatite B et production

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BIOTECHNOLOGY, vol. 3, avril 1985, pages 317-320; P. VALENZUELA et al.: "Synthesis and assembly in yeast of hepatitis B surface antigen particles containing the polyalbumin receptor" *
GENE, vol. 40, no. 1, 1985, pages 23-29, Elsevier Science Publishers, Amsterdam, NL; Y. FUJISAWA et al.: "Expression of hepatitis B virus surface antigen P31 gene in Escherichia coli" *
NATURE, vol. 317, no. 6037, octobre 1985, pages 489-495, Londres, GB; P. TIOLLAIS et al.: "The hepatitis B virus" *
NUCLEIC ACIDS RESEARCH, vol. 11, no. 13, juillet 1983, pages 4601-4610, IRL Press Ltd, Cambridge, GB; A. FUJIYAMA et al.: "Cloning and structural analyses of hepatitis B virus DNAs, subtype adr" *
NUCLEIC ACIDS RESEARCH, vol. 11, no. 6, 1983, pages 1657-1672, Oxford, GB; K. ARIMA et al.: "The nucleotide sequence of the yeast PHO5 gene: a putative precursor of repressible acid phosphatase contains a signal peptide" *

Also Published As

Publication number Publication date
US5693497A (en) 1997-12-02
CA1340521C (fr) 1999-05-04
JPH089637B2 (ja) 1996-01-31
FR2606281A1 (fr) 1988-05-13
JPS6322098A (ja) 1988-01-29
FR2606281B1 (fr) 1990-10-12

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RE Patent lapsed

Owner name: *THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OF

Effective date: 20020630