BE1002130A3 - Procede de preparation de complexes de metalloproteines et nouveaux derives de ceux-ci. - Google Patents

Procede de preparation de complexes de metalloproteines et nouveaux derives de ceux-ci. Download PDF

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Publication number
BE1002130A3
BE1002130A3 BE8700605A BE8700605A BE1002130A3 BE 1002130 A3 BE1002130 A3 BE 1002130A3 BE 8700605 A BE8700605 A BE 8700605A BE 8700605 A BE8700605 A BE 8700605A BE 1002130 A3 BE1002130 A3 BE 1002130A3
Authority
BE
Belgium
Prior art keywords
preparation
new derivatives
complexes
metalloprotein
metalloprotein complexes
Prior art date
Application number
BE8700605A
Other languages
English (en)
Original Assignee
Debiopharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Sa filed Critical Debiopharm Sa
Application granted granted Critical
Publication of BE1002130A3 publication Critical patent/BE1002130A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Un procédé pour la préparation de complexes de métalloprotéines biologiquement actifs sans perte d'activité comprend de préparer de nouveaux complexes des apoprotéines correspondantes, à les purifier et à reconstituer l'activité biologique en ajoutant des métaux.
BE8700605A 1986-06-02 1987-06-01 Procede de preparation de complexes de metalloproteines et nouveaux derives de ceux-ci. BE1002130A3 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8613315A GB2191200B (en) 1986-06-02 1986-06-02 Process for preparing conjugates of metalloproteins and novel derivatives thereof

Publications (1)

Publication Number Publication Date
BE1002130A3 true BE1002130A3 (fr) 1990-07-24

Family

ID=10598769

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8700605A BE1002130A3 (fr) 1986-06-02 1987-06-01 Procede de preparation de complexes de metalloproteines et nouveaux derives de ceux-ci.

Country Status (10)

Country Link
JP (1) JPS62292800A (fr)
BE (1) BE1002130A3 (fr)
CH (1) CH674939A5 (fr)
DE (1) DE3718476A1 (fr)
DK (1) DK280187A (fr)
ES (1) ES2004734A6 (fr)
FR (1) FR2603287B1 (fr)
GB (1) GB2191200B (fr)
IT (1) IT1207805B (fr)
NL (1) NL8701254A (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1317895B1 (it) * 2000-08-10 2003-07-15 Univ Napoli Federico Ii Pseudo-metalloproteine, loro preparazione e loro uso.
MX354530B (es) * 2013-02-27 2018-02-19 Univ Autonoma Del Estado De Morelos Composiciones que comprenden immp para coadyuvar al desarrollo, crecimiento y mejora de los parámetros productivos de animales de interés zootécnico, y uso de las mismas.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1168150A (fr) * 1981-12-18 1984-05-29 The Governors Of The University Of Alberta Conjugats d'albumine et d'agents therapeutiques

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1168150A (fr) * 1981-12-18 1984-05-29 The Governors Of The University Of Alberta Conjugats d'albumine et d'agents therapeutiques

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 101, no. 14, 1er octobre 1984, page 352, résumé no. 116715v, Columbus, Ohio, US; & CA-A-1 168 150 (UNIVERSITY OF ALBERTA) 29-05-1984 *
CHEMICAL ABSTRACTS, vol. 102, no. 6, 11 février 1985, page 322, résumé no. 50880g, Columbus, Ohio, US; C.F. MEARES et al.: "Conjugation of antibodies with bifunctional chelating agents: isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions", & ANAL. BIOCHEM. 1984, 142(1), 68-78 *
CHEMICAL ABSTRACTS, vol. 93, no. 7, 18 août 1980, page 96, résumé no. 61591k, Columbus, Ohio, US; K. WONG et al.: "Enhanced anti-inflammatory effect and reduced immunogenicity of bovine liver superoxide dismutase by conjugation with homologous albumin", & AGENTS ACTIONS 1980, 10(3), 231-9 *
CHEMICAL ABSTRACTS, vol. 99, no. 25, 19 décembre 1983, page 38, résumé no. 205791z, Columbus, Ohio, US; A. BARET et al.: "Pharmacokinetic and antiinflammatory properties of human copper and manganese containing superoxide dismutase in the rat", & OXY RADICALS THEIR SCAVENGER SYST., PROC. INT. CONF. SUPEROXIDE SUPEROXIDE DISMUTASE, 3rd 1982 (Pub. 1983), 2, 274-80 *

Also Published As

Publication number Publication date
DE3718476A1 (de) 1987-12-03
FR2603287A1 (fr) 1988-03-04
GB2191200A (en) 1987-12-09
CH674939A5 (fr) 1990-08-15
DK280187A (da) 1987-12-03
ES2004734A6 (es) 1989-02-01
NL8701254A (nl) 1988-01-04
IT1207805B (it) 1989-06-01
JPS62292800A (ja) 1987-12-19
IT8705187A0 (it) 1987-06-01
FR2603287B1 (fr) 1991-02-08
GB8613315D0 (en) 1986-07-09
DK280187D0 (da) 1987-06-01
GB2191200B (en) 1990-07-11

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: S.A. DEBIOPHARMS

Effective date: 19920630