BE1002255A5 - Medicaments. - Google Patents
Medicaments. Download PDFInfo
- Publication number
- BE1002255A5 BE1002255A5 BE8900221A BE8900221A BE1002255A5 BE 1002255 A5 BE1002255 A5 BE 1002255A5 BE 8900221 A BE8900221 A BE 8900221A BE 8900221 A BE8900221 A BE 8900221A BE 1002255 A5 BE1002255 A5 BE 1002255A5
- Authority
- BE
- Belgium
- Prior art keywords
- methyl
- acceptable salts
- physiologically acceptable
- drugs
- carbazol
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- FELGMEQIXOGIFQ-UHFFFAOYSA-N Ondansetron Chemical compound CC1=NC=CN1CC1C(=O)C(C=2C(=CC=CC=2)N2C)=C2CC1 FELGMEQIXOGIFQ-UHFFFAOYSA-N 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- AMLYRCOEFHJSFS-UHFFFAOYSA-N carbazol-1-one Chemical compound C1=CC=C2C3=CC=CC(=O)C3=NC2=C1 AMLYRCOEFHJSFS-UHFFFAOYSA-N 0.000 abstract 1
- 238000011260 co-administration Methods 0.000 abstract 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 1
- 229960003957 dexamethasone Drugs 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne la co-administration en médecine humaine ou vétérinaire de 1,2,3,9-tétrahydro-9-méthyl-3-[(2-méthyl-1H-imidazol-1-yl)méthyl]-4H-carbazol-4-one ou d'un de ses sels ou produits de solvatation physiologiquement acceptables et de dexaméthasone ou d'un de ses sels ou esters physiologiquement acceptables. Les deux ingrédients actifs, qui peuvent être administrés séparément simultanément ou de façon séquentielle, ou peuvent être combinés en en une seule préparation pharmaceutique, sont utiles pour soulager et/ou prévenir la nausée et le vomissement.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888805269A GB8805269D0 (en) | 1988-03-04 | 1988-03-04 | Medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE1002255A5 true BE1002255A5 (fr) | 1990-11-06 |
Family
ID=10632894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE8900221A BE1002255A5 (fr) | 1988-03-04 | 1989-03-03 | Medicaments. |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6544550B1 (fr) |
| JP (1) | JPH0296525A (fr) |
| KR (1) | KR890014109A (fr) |
| AT (1) | AT400301B (fr) |
| AU (1) | AU626010B2 (fr) |
| BE (1) | BE1002255A5 (fr) |
| CA (1) | CA1319323C (fr) |
| CH (1) | CH678149A5 (fr) |
| CY (1) | CY1634A (fr) |
| CZ (1) | CZ402391A3 (fr) |
| DE (1) | DE3906883C2 (fr) |
| DK (1) | DK175428B1 (fr) |
| FR (1) | FR2627986B1 (fr) |
| GB (2) | GB8805269D0 (fr) |
| HK (1) | HK41792A (fr) |
| IE (1) | IE61516B1 (fr) |
| IT (1) | IT1232662B (fr) |
| NL (1) | NL194463C (fr) |
| NZ (1) | NZ228214A (fr) |
| SE (1) | SE508342C2 (fr) |
| SG (1) | SG9092G (fr) |
| SK (1) | SK402391A3 (fr) |
| ZA (1) | ZA891639B (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5929059A (en) * | 1991-01-19 | 1999-07-27 | Smithkline Beecham P.L.C. | Pharmaceutical compositions containing granisetron and dexamethasone |
| GB9101221D0 (en) * | 1991-01-19 | 1991-02-27 | Smithkline Beecham Plc | Pharmaceuticals |
| ATE195867T1 (de) * | 1991-09-20 | 2000-09-15 | Glaxo Group Ltd | Neue medizinische indikation für tachykinin- antagonisten |
| CN1118990A (zh) * | 1993-03-08 | 1996-03-20 | 藤泽药品工业株式会社 | 治疗或预防脑血管疾病药物 |
| US5661142A (en) * | 1996-04-17 | 1997-08-26 | Naeger; David M. | Anti-emetic composition |
| US7288660B2 (en) * | 2004-05-07 | 2007-10-30 | Taro Pharmaceutical Industries Limited | Process for preparing ondansetron hydrochloride dihydrate having a defined particle size |
| US20050277624A1 (en) * | 2004-06-09 | 2005-12-15 | Nigel Cook | Use of corticosteroids alone or in conjunction with nutritional therapy to reduce stress in animals |
| US20060263421A1 (en) * | 2005-05-18 | 2006-11-23 | Abeille Pharmaceuticals Inc | Transdermal Method and Patch for Nausea |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2153821A (en) * | 1984-01-25 | 1985-08-29 | Glaxo Group Ltd | 3-Imidazolylmethyl-1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives |
| EP0226266A2 (fr) * | 1985-06-25 | 1987-06-24 | Glaxo Group Limited | Utilisation d'un dérivé du tétrahydrocarbazolone pour la fabrication de médicaments |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0191562B1 (fr) * | 1985-01-23 | 1991-07-10 | Glaxo Group Limited | Dérivés de tétrahydrocarbazolones |
| DE3688296T2 (de) * | 1985-03-14 | 1993-11-04 | Beecham Group Plc | Arzneimittel zur behandlung von erbrechen. |
| GB8628475D0 (en) * | 1986-11-28 | 1987-01-07 | Glaxo Group Ltd | Medicaments |
| PH25025A (en) * | 1986-12-17 | 1991-01-28 | Glaxo Group Ltd | A method of treating dementia and other cognitive disorders using 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1h-imidazol-1-yl)methyl)-4h-carbazol-4-one |
| US4920219A (en) * | 1988-11-29 | 1990-04-24 | Rorer Pharmaceutical Corp. | Substituted saturated and unsaturated indole quinoline and benzazepine carboxamides and their use as pharmacological agents |
| US5166145A (en) * | 1990-09-10 | 1992-11-24 | Alza Corporation | Antiemetic therapy |
| US5246709A (en) * | 1990-09-10 | 1993-09-21 | Alza Corporation | Antiemetic therapy |
-
1988
- 1988-03-04 GB GB888805269A patent/GB8805269D0/en active Pending
-
1989
- 1989-03-03 GB GB8904881A patent/GB2216414B/en not_active Expired - Lifetime
- 1989-03-03 SE SE8900751A patent/SE508342C2/sv unknown
- 1989-03-03 AU AU30976/89A patent/AU626010B2/en not_active Expired
- 1989-03-03 FR FR898902779A patent/FR2627986B1/fr not_active Expired - Lifetime
- 1989-03-03 CA CA000592765A patent/CA1319323C/fr not_active Expired - Lifetime
- 1989-03-03 AT AT0048389A patent/AT400301B/de not_active IP Right Cessation
- 1989-03-03 IE IE69789A patent/IE61516B1/en not_active IP Right Cessation
- 1989-03-03 ZA ZA891639A patent/ZA891639B/xx unknown
- 1989-03-03 NZ NZ228214A patent/NZ228214A/en unknown
- 1989-03-03 DK DK198901043A patent/DK175428B1/da not_active IP Right Cessation
- 1989-03-03 BE BE8900221A patent/BE1002255A5/fr not_active IP Right Cessation
- 1989-03-03 NL NL8900526A patent/NL194463C/nl not_active IP Right Cessation
- 1989-03-03 CH CH805/89A patent/CH678149A5/fr not_active IP Right Cessation
- 1989-03-03 DE DE3906883A patent/DE3906883C2/de not_active Expired - Lifetime
- 1989-03-03 IT IT8947713A patent/IT1232662B/it active
- 1989-03-03 JP JP1051814A patent/JPH0296525A/ja active Pending
- 1989-03-03 KR KR1019890002613A patent/KR890014109A/ko not_active Ceased
-
1991
- 1991-12-23 SK SK4023-91A patent/SK402391A3/sk unknown
- 1991-12-23 CZ CS914023A patent/CZ402391A3/cs unknown
-
1992
- 1992-01-30 SG SG90/92A patent/SG9092G/en unknown
- 1992-06-11 HK HK417/92A patent/HK41792A/xx not_active IP Right Cessation
- 1992-11-06 CY CY1634A patent/CY1634A/en unknown
-
1993
- 1993-11-24 US US08/156,727 patent/US6544550B1/en not_active Expired - Fee Related
-
1994
- 1994-05-27 US US08/250,960 patent/US5482716A/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2153821A (en) * | 1984-01-25 | 1985-08-29 | Glaxo Group Ltd | 3-Imidazolylmethyl-1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives |
| EP0226266A2 (fr) * | 1985-06-25 | 1987-06-24 | Glaxo Group Limited | Utilisation d'un dérivé du tétrahydrocarbazolone pour la fabrication de médicaments |
Non-Patent Citations (1)
| Title |
|---|
| CHEMICAL ABSTRACTS, vol. 104, no. 21, 26 mai 1986, page 27, abrégé no. 179831n, Columbus, Ohio, US; M. HUO et al.: "Emesis induced by cisplatin and sulfatol 2-diaminocyclohexaneplatinum in dogs and its inhibition by antiemetics", & ZHONGGUO YAOLI XUEBAO 1986, 7(2), 182-4 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE20 | Patent expired |
Owner name: *GLAXO GROUP LTD Effective date: 20090303 |