BE1003340A3 - Nouvelle utilisation therapeutique des alpha-aminofluorocetones. - Google Patents

Nouvelle utilisation therapeutique des alpha-aminofluorocetones. Download PDF

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Publication number
BE1003340A3
BE1003340A3 BE9000075A BE9000075A BE1003340A3 BE 1003340 A3 BE1003340 A3 BE 1003340A3 BE 9000075 A BE9000075 A BE 9000075A BE 9000075 A BE9000075 A BE 9000075A BE 1003340 A3 BE1003340 A3 BE 1003340A3
Authority
BE
Belgium
Prior art keywords
alpha
aminofluorocetones
therapeutic use
new therapeutic
phenylalanylalanylfluoromethylketone
Prior art date
Application number
BE9000075A
Other languages
English (en)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Application granted granted Critical
Publication of BE1003340A3 publication Critical patent/BE1003340A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)

Abstract

La présente invention a pour objet l'utilisation d'alpha-aminofluorocétones, spécialement la benzyloxycarbonyl-1-phénylalanylalanylfluorométhylcétone, pour la préparation de médicaments ayant une activité cardiovasculaire et anti-hypertensive.
BE9000075A 1989-01-26 1990-01-22 Nouvelle utilisation therapeutique des alpha-aminofluorocetones. BE1003340A3 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH23889 1989-01-26

Publications (1)

Publication Number Publication Date
BE1003340A3 true BE1003340A3 (fr) 1992-03-03

Family

ID=4182438

Family Applications (1)

Application Number Title Priority Date Filing Date
BE9000075A BE1003340A3 (fr) 1989-01-26 1990-01-22 Nouvelle utilisation therapeutique des alpha-aminofluorocetones.

Country Status (6)

Country Link
JP (1) JPH02247123A (fr)
BE (1) BE1003340A3 (fr)
DE (1) DE4001087A1 (fr)
FR (1) FR2641972A1 (fr)
GB (1) GB2227411A (fr)
IT (1) IT1239745B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5101068A (en) * 1990-02-16 1992-03-31 Prototek Inc. Magnesium fluoromalonates
JP3228347B2 (ja) * 1991-06-25 2001-11-12 三菱化学株式会社 シクロプロペノン誘導体
US5395958A (en) * 1992-09-30 1995-03-07 Mitsubishi Kasei Corporation Cyclopropene derivatives
DE69610978D1 (de) * 1995-03-31 2000-12-21 Naeja Pharmaceutical Inc 4-substituierte-3-peptidyl-azetidin-2-on-derivate als cystein-proteinase inhibitoren

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518528A (en) * 1983-05-19 1985-05-21 Rasnick David W α Amino fluoro ketones

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518528A (en) * 1983-05-19 1985-05-21 Rasnick David W α Amino fluoro ketones

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 108, no. 17, 25 avril 1988, page 798, abr�g� no. 150981h, Columbus, Ohio, US; & ZA-A-86 06 642 (MERCK & CO., INC.) 29-04-1987 *
CHEMICAL ABSTRACTS, vol. 86, no. 11, 14 mars 1977, page 186, abr�g� no. 67205q, Columbus, Ohio, US; V.N. OREKHOVICH et al.: "Enzymological factors in vascular tension regulation", & VESTN. AKAD. MED. NAUK. SSSR 1976, (9), 42-7 *

Also Published As

Publication number Publication date
IT1239745B (it) 1993-11-15
JPH02247123A (ja) 1990-10-02
GB2227411A (en) 1990-08-01
IT9047551A0 (it) 1990-01-22
GB9001453D0 (en) 1990-03-21
IT9047551A1 (it) 1990-07-27
FR2641972A1 (fr) 1990-07-27
DE4001087A1 (de) 1990-08-02

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: S.A. SANDOZ

Effective date: 19920131