BE668977A - - Google Patents
Info
- Publication number
- BE668977A BE668977A BE668977DA BE668977A BE 668977 A BE668977 A BE 668977A BE 668977D A BE668977D A BE 668977DA BE 668977 A BE668977 A BE 668977A
- Authority
- BE
- Belgium
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/60—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEC33812A DE1235320B (de) | 1964-09-05 | 1964-09-05 | Verfahren zur Herstellung von 1-(Oxoalkyl)-3, 7-dimethylxanthinen |
| DEC33811A DE1233405B (de) | 1964-09-05 | 1964-09-05 | Verfahren zur Herstellung von 7-(Oxoalkyl)-1, 3-dimethylxanthinen |
| DEC0036289 | 1965-07-02 | ||
| DEC0036362 | 1965-07-10 | ||
| DEC0036493 | 1965-07-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE668977A true BE668977A (fr) | 1966-02-28 |
Family
ID=27511962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE668977D BE668977A (fr) | 1964-09-05 | 1965-08-31 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3422107A (fr) |
| BE (1) | BE668977A (fr) |
| CH (2) | CH540275A (fr) |
| FR (1) | FR4791M (fr) |
| GB (1) | GB1079267A (fr) |
| IT (1) | IT1054101B (fr) |
| NL (1) | NL6511581A (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2381522A1 (fr) * | 1977-02-26 | 1978-09-22 | Basf Ag | Utilisation de l'ether 1,2-propylene-glycol-1-n-propylique comme solvant pour preparations pharmaceutiques |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2366501C2 (de) * | 1973-06-16 | 1983-11-24 | Hoechst Ag, 6230 Frankfurt | 1-Alkyl-3-methyl-7-oxoalkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| DE2330742C2 (de) | 1973-06-16 | 1982-07-29 | Hoechst Ag, 6000 Frankfurt | 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| DE2507555A1 (de) * | 1975-02-21 | 1976-09-02 | Wuelfing J A Fa | 7-(oxoalkyl)-1,3-dialkylxanthine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel |
| JPS5275920U (fr) * | 1975-12-05 | 1977-06-07 | ||
| US4156736A (en) * | 1976-05-28 | 1979-05-29 | Sanol Schwarz-Monheim Gmbh | Supersaturated isosorbide dinitrate solution, process for its production and its use |
| US4636507A (en) * | 1984-04-30 | 1987-01-13 | Hoechst-Roussel Pharmaceuticals Inc. | Host defense mechanism enhancement |
| DE3604149A1 (de) * | 1986-02-10 | 1987-08-13 | Rentschler Arzneimittel | Arzneimittelkombination |
| CA2030112A1 (fr) * | 1989-11-24 | 1991-05-25 | Yasuo Ito | Compose de xanthine, methode de preparation et composition pharmaceutique contenant ledit compose |
| US6420374B1 (en) | 1990-11-30 | 2002-07-16 | Fred Hutchinson Cancer Research Center | Use of xanthines as immunosuppressants and to inhibit allograft reactions |
| US5856115A (en) * | 1991-05-24 | 1999-01-05 | Fred Hutchinson Cancer Research Center | Assay for identification therapeutic agents |
| US5580873A (en) * | 1992-03-04 | 1996-12-03 | Cell Therapeutics, Inc. | Enatiomerically pure hydroxylated xanthine compounds to treat proliferative vascular diseases |
| ATE230990T1 (de) * | 1992-03-04 | 2003-02-15 | Cell Therapeutics Inc | Enantiomere hydroxylierte xanthinverbindungen |
| US5648357A (en) * | 1992-03-04 | 1997-07-15 | Cell Therapeutics, Inc. | Enatiomerically pure hydroxylated xanthine compounds |
| US5288721A (en) * | 1992-09-22 | 1994-02-22 | Cell Therapeutics, Inc. | Substituted epoxyalkyl xanthines |
| US5817662A (en) * | 1992-11-09 | 1998-10-06 | Cell Therapeutics, Inc. | Substituted amino alkyl compounds |
| US6693105B1 (en) | 1992-11-16 | 2004-02-17 | Cell Therapeutics, Inc. | Hydroxyl-containing compounds |
| US5804584A (en) * | 1992-11-16 | 1998-09-08 | Cell Therapeutics, Inc. | Therapeutic compounds containing a monocyclic five- to six- membered ring structure having one to two nitrogen atoms |
| US5795897A (en) * | 1992-11-18 | 1998-08-18 | Cell Therapeutics, Inc. | Oxohexyl methylxanthine compounds |
| US5866576A (en) * | 1992-12-16 | 1999-02-02 | Cell Therapeutics, Inc. | Epoxide-containing compounds |
| WO1994015605A1 (fr) * | 1993-01-14 | 1994-07-21 | Cell Therapeutics, Inc. | Composes therapeutiques a substitution acetal ou cetal |
| WO1994016704A1 (fr) * | 1993-01-19 | 1994-08-04 | Cell Therapeutics, Inc. | Composes therapeutiques a substitution oxime |
| US5837703A (en) * | 1993-03-31 | 1998-11-17 | Cell Therapeutics, Inc. | Amino-alcohol substituted cyclic compounds |
| US5641783A (en) * | 1993-11-12 | 1997-06-24 | Cell Therapeutics, Inc. | Substituted amino alcohol compounds |
| US6020337A (en) * | 1993-04-05 | 2000-02-01 | Cell Therapeutics, Inc. | Electronegative-substituted long chain xanthine compounds |
| US5532003A (en) * | 1994-01-18 | 1996-07-02 | Alza Corporation | Pentoxifylline therapy |
| AU1967495A (en) * | 1994-02-18 | 1995-09-04 | Cell Therapeutics, Inc. | Intracellular signalling mediators |
| US5801182A (en) * | 1994-03-24 | 1998-09-01 | Cell Therapeutics, Inc. | Amine substituted compounds |
| US5807861A (en) * | 1994-03-24 | 1998-09-15 | Cell Therapeutics, Inc. | Amine substituted xanthinyl compounds |
| US20030207901A1 (en) * | 1999-07-27 | 2003-11-06 | Cell Therapeutics, Inc. | Hydroxyl-containing compounds |
| EP1545519B1 (fr) | 2002-08-19 | 2011-03-23 | Pfizer Inc. | Therapie de combinaison pour maladies hyperproliferatives |
| US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
| US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| JP5498168B2 (ja) | 2006-12-01 | 2014-05-21 | ブリストル−マイヤーズ スクイブ カンパニー | アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体 |
| WO2011108001A2 (fr) | 2010-03-02 | 2011-09-09 | Spc Lifesciences Pvt Ltd | Procédé de préparation de méthyl-méthyl-3, 4-dihydro-2h-pyran-5-carboxylate |
| ES2395801B1 (es) | 2011-06-23 | 2014-06-06 | María Carmen PARDINA PALLEJÀ | "pentoxifilina por vía transvaginal para el tratamiento de la infertilidad" |
| SG11201507496UA (en) | 2013-04-17 | 2015-11-27 | Pfizer | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
| WO2016055901A1 (fr) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Composés d'amide substitué |
| US11248001B2 (en) | 2019-01-18 | 2022-02-15 | Astrazeneca Ab | PCSK9 inhibitors and methods of use thereof |
| WO2024161377A1 (fr) | 2023-02-04 | 2024-08-08 | Lavender Laboratories Private Limited | Procédé de préparation d'halo-alkyl-cétone |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2776300A (en) * | 1951-08-31 | 1957-01-01 | Searle & Co | Basic esters of substituted 3, 4-dihydro-1, 2-pyran-5-carboxylic acids and salts thereof |
| GB759981A (en) * | 1953-09-09 | 1956-10-24 | Roche Products Ltd | Process for the manufacture of xanthine derivatives |
| US3029239A (en) * | 1954-04-17 | 1962-04-10 | Chemiewerk Homburg Zweignieder | Basic substituted 1-and 7-alkylxanthines or salts thereof |
| US2815379A (en) * | 1954-09-13 | 1957-12-03 | Hoffmann La Roche | Alicyclic ketone and intermediates for the preparation thereof |
| AT216011B (de) * | 1958-08-16 | 1961-07-10 | Chemiewerk Homburg | Verfahren zur Herstellung von neuen Oxygruppen tragenden 1-bzw. 7-Aminoalkylxanthinderivaten |
| US3030363A (en) * | 1959-06-10 | 1962-04-17 | Boehringer Sohn Ingelheim | Derivatives of xanthine |
| US3122587A (en) * | 1959-11-13 | 1964-02-25 | Union Carbide Corp | Process of producing 6-halo-2, 5-dimethylhexanone-3 |
-
1965
- 1965-08-30 US US483803A patent/US3422107A/en not_active Expired - Lifetime
- 1965-08-31 BE BE668977D patent/BE668977A/xx unknown
- 1965-08-31 CH CH1215465A patent/CH540275A/de not_active IP Right Cessation
- 1965-08-31 CH CH1148769A patent/CH555352A/de not_active IP Right Cessation
- 1965-09-02 FR FR30215A patent/FR4791M/fr not_active Expired
- 1965-09-03 GB GB37784/65A patent/GB1079267A/en not_active Expired
- 1965-09-04 IT IT19813/65A patent/IT1054101B/it active
- 1965-09-06 NL NL6511581A patent/NL6511581A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2381522A1 (fr) * | 1977-02-26 | 1978-09-22 | Basf Ag | Utilisation de l'ether 1,2-propylene-glycol-1-n-propylique comme solvant pour preparations pharmaceutiques |
Also Published As
| Publication number | Publication date |
|---|---|
| CH540275A (de) | 1973-08-15 |
| NL6511581A (fr) | 1966-03-07 |
| US3422107A (en) | 1969-01-14 |
| GB1079267A (en) | 1967-08-16 |
| FR4791M (fr) | 1967-01-30 |
| IT1054101B (it) | 1981-11-10 |
| CH555352A (de) | 1974-10-31 |