BE775775A - Oligopeptides contenant de la m-(di-(2-chlorethyl)amino)-l-phenylalanine. - Google Patents

Oligopeptides contenant de la m-(di-(2-chlorethyl)amino)-l-phenylalanine.

Info

Publication number: BE775775A
Authority: BE; Belgium
Prior art keywords: ester; amino; oligopeptides; chloroethyl; antitumour
Prior art date: 1971-11-24

Application number

BE775775A

Other languages

English (en)

Original Assignee

Belfanti Ist Sieroterap Milan

Belfanti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-11-24

Filing date

1971-11-24

Publication date

1972-03-16

1971-11-24 Application filed by Belfanti Ist Sieroterap Milan, Belfanti filed Critical Belfanti Ist Sieroterap Milan

1971-11-24 Priority to BE775775A priority Critical patent/BE775775A/fr

1972-03-16 Publication of BE775775A publication Critical patent/BE775775A/fr

Links

108010038807 Oligopeptides Proteins 0.000 title abstract 2
102000015636 Oligopeptides Human genes 0.000 title abstract 2
230000000259 anti-tumor effect Effects 0.000 title abstract 2
150000002148 esters Chemical class 0.000 abstract 9
-1 (N-formyl)p-fluorophenylalanyl Chemical group 0.000 abstract 3
XWHHYOYVRVGJJY-UHFFFAOYSA-N 4-fluorophenylalanine Chemical compound OC(=O)C(N)CC1=CC=C(F)C=C1 XWHHYOYVRVGJJY-UHFFFAOYSA-N 0.000 abstract 1
DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 abstract 1
ATIPDCIQTUXABX-UWVGGRQHSA-N Lys-Leu Chemical compound CC(C)C[C@@H](C(O)=O)NC(=O)[C@@H](N)CCCCN ATIPDCIQTUXABX-UWVGGRQHSA-N 0.000 abstract 1
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
239000004472 Lysine Substances 0.000 abstract 1
UAGJVSRUFNSIHR-UHFFFAOYSA-N Methyl levulinate Chemical compound COC(=O)CCC(C)=O UAGJVSRUFNSIHR-UHFFFAOYSA-N 0.000 abstract 1
229940024606 amino acid Drugs 0.000 abstract 1
235000001014 amino acid Nutrition 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
229960001230 asparagine Drugs 0.000 abstract 1
235000009582 asparagine Nutrition 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
125000000717 hydrazino group Chemical group [H]N([*])N([H])[H] 0.000 abstract 1
108010008606 lysyl-leucine Proteins 0.000 abstract 1
125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)

BE775775A 1971-11-24 1971-11-24 Oligopeptides contenant de la m-(di-(2-chlorethyl)amino)-l-phenylalanine. BE775775A (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
BE775775A BE775775A (fr)	1971-11-24	1971-11-24	Oligopeptides contenant de la m-(di-(2-chlorethyl)amino)-l-phenylalanine.

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
BE775775A BE775775A (fr)	1971-11-24	1971-11-24	Oligopeptides contenant de la m-(di-(2-chlorethyl)amino)-l-phenylalanine.

Publications (1)

Publication Number	Publication Date
BE775775A true BE775775A (fr)	1972-03-16

Family

ID=3858916

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE775775A BE775775A (fr)	1971-11-24	1971-11-24	Oligopeptides contenant de la m-(di-(2-chlorethyl)amino)-l-phenylalanine.

Country Status (1)

Country	Link
BE (1)	BE775775A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000031119A1 (fr) *	1998-11-19	2000-06-02	Ptc Pharma Ag	Procede de production de l-prolyl-l-m-sarcolysyl-l-p-fluorophenylalanine et de ses derives

1971
- 1971-11-24 BE BE775775A patent/BE775775A/fr not_active IP Right Cessation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000031119A1 (fr) *	1998-11-19	2000-06-02	Ptc Pharma Ag	Procede de production de l-prolyl-l-m-sarcolysyl-l-p-fluorophenylalanine et de ses derives
US6767992B1 (en)	1998-11-19	2004-07-27	Ptc Pharma Ag	Method for producing L-prolyl-L-M-sarcolysyl-L-p-fluorophenylalanine and derivatives thereof

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Legal Events

Date

Code

Title

Description

1991-01-01

RE20

Patent expired

Owner name: ISTITUTO SIEROTERAPICO MILANESE S. BELFANTI

Effective date: 19911124