BE812375A - 4'-alkyldioxyalkylene-5-benzylpyrimidines - Google Patents

4'-alkyldioxyalkylene-5-benzylpyrimidines

Info

Publication number
BE812375A
BE812375A BE142065A BE142065A BE812375A BE 812375 A BE812375 A BE 812375A BE 142065 A BE142065 A BE 142065A BE 142065 A BE142065 A BE 142065A BE 812375 A BE812375 A BE 812375A
Authority
BE
Belgium
Prior art keywords
alkyldioxyalkylene
benzylpyrimidines
Prior art date
Application number
BE142065A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732313361 external-priority patent/DE2313361C3/de
Application filed filed Critical
Publication of BE812375A publication Critical patent/BE812375A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BE142065A 1973-03-17 1974-03-15 4'-alkyldioxyalkylene-5-benzylpyrimidines BE812375A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732313361 DE2313361C3 (de) 1973-03-17 2,4-Diamino-5-(3',5'-dimethoxy-4'-methoxyalkoxybenzyl-pyrimidine

Publications (1)

Publication Number Publication Date
BE812375A true BE812375A (fr) 1974-07-01

Family

ID=5875077

Family Applications (1)

Application Number Title Priority Date Filing Date
BE142065A BE812375A (fr) 1973-03-17 1974-03-15 4'-alkyldioxyalkylene-5-benzylpyrimidines

Country Status (16)

Country Link
US (1) US3992379A (fr)
JP (1) JPS584025B2 (fr)
AR (1) AR207561A1 (fr)
AT (1) AT338795B (fr)
AU (1) AU476979B2 (fr)
BE (1) BE812375A (fr)
BR (1) BR7401966D0 (fr)
CA (1) CA1063607A (fr)
CH (1) CH601257A5 (fr)
ES (1) ES424274A1 (fr)
FR (1) FR2221147B1 (fr)
GB (1) GB1413454A (fr)
HK (1) HK50580A (fr)
HU (1) HU166864B (fr)
IT (1) IT1060117B (fr)
NL (1) NL175414C (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115650A (en) * 1976-11-17 1978-09-19 Hoffmann-La Roche Inc. Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines
US4103902A (en) * 1977-08-16 1978-08-01 Foster Wheeler Energy Corporation Water seal for regenerator
US4258045A (en) * 1979-11-30 1981-03-24 Merck & Co., Inc. Inhibitor of dihydrofolate reductase
EP0054756B1 (fr) * 1980-11-27 1986-07-23 The Wellcome Foundation Limited Benzylpyrimidines antibactériennes
JPS60107889U (ja) * 1983-12-20 1985-07-22 トキコ株式会社 給油量表示装置
DE3613794A1 (de) * 1986-04-24 1987-10-29 Frank Joachim Mueller Verfahren zum nachweis von antibiotika- und sulfonamidrueckstaenden in biologischen fluessigkeiten oder nahrungsmitteln

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2909522A (en) * 1957-02-21 1959-10-20 Burroughs Wellcome Co Trialkoxybenzylpyrimidines and method
GB1142654A (en) * 1965-10-28 1969-02-12 Wellcome Found Cyano-acetals and their use in benzylpyrimidine synthesis
GB1229413A (fr) * 1967-06-14 1971-04-21
US3849407A (en) * 1969-03-06 1974-11-19 Burroughs Wellcome Co 5-benzyl pyrimidines intermediates
US3819629A (en) * 1970-02-10 1974-06-25 Burroughs Wellcome Co Method for preparing 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
US3692787A (en) * 1970-02-16 1972-09-19 Burroughs Wellcome Co Substituted 2,4-diamino-5-benzyl pyrimidines
US3772289A (en) * 1970-10-22 1973-11-13 Burroughs Wellcome Co Alkyl substituted benzyl pyrimidines

Also Published As

Publication number Publication date
JPS5035176A (fr) 1975-04-03
HU166864B (fr) 1975-06-28
HK50580A (en) 1980-09-12
DE2313361B2 (de) 1975-07-10
AU6671374A (en) 1975-09-18
FR2221147A1 (fr) 1974-10-11
NL175414C (nl) 1984-11-01
AU476979B2 (en) 1976-10-07
CA1063607A (fr) 1979-10-02
IT1060117B (it) 1982-07-10
NL7403411A (fr) 1974-09-19
FR2221147B1 (fr) 1982-06-11
ATA215474A (de) 1977-01-15
ES424274A1 (es) 1976-11-01
US3992379A (en) 1976-11-16
AR207561A1 (es) 1976-10-15
BR7401966D0 (pt) 1974-11-05
AT338795B (de) 1977-09-12
JPS584025B2 (ja) 1983-01-24
CH601257A5 (fr) 1978-06-30
NL175414B (nl) 1984-06-01
GB1413454A (en) 1975-11-12
DE2313361A1 (de) 1975-02-06

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: LUDWIG HEUMANN & CO. G.M.B.H.

Effective date: 19940315