BE815488A - Nouvelles imidazolido - Google Patents

Nouvelles imidazolido

Info

Publication number: BE815488A
Authority: BE; Belgium
Prior art keywords: manic; cpds; treating schizophrenia; imidazolido; piperidins
Prior art date: 1973-05-28

Application number

BE144705A

Other languages

English (en)

Inventor

K Arimura

H Ao

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-05-28

Filing date

1974-05-24

Publication date

1974-09-16

1974-05-24 Application filed filed Critical

1974-09-16 Publication of BE815488A publication Critical patent/BE815488A/fr

Links

206010026749 Mania Diseases 0.000 title abstract 2
201000000980 schizophrenia Diseases 0.000 title abstract 2
-1 4,5,6-trimethoxybenzyl Chemical group 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 3
125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 2
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
RHCSKNNOAZULRK-UHFFFAOYSA-N mescaline Chemical compound COC1=CC(CCN)=CC(OC)=C1OC RHCSKNNOAZULRK-UHFFFAOYSA-N 0.000 abstract 2
DNXIKVLOVZVMQF-UHFFFAOYSA-N (3beta,16beta,17alpha,18beta,20alpha)-17-hydroxy-11-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(C(=O)OC)C(O)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 DNXIKVLOVZVMQF-UHFFFAOYSA-N 0.000 abstract 1
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
125000001494 2-propynyl group Chemical group [H]C#CC([H])([H])* 0.000 abstract 1
125000006283 4-chlorobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])* 0.000 abstract 1
241000699670 Mus sp. Species 0.000 abstract 1
LCQMZZCPPSWADO-UHFFFAOYSA-N Reserpilin Natural products COC(=O)C1COCC2CN3CCc4c([nH]c5cc(OC)c(OC)cc45)C3CC12 LCQMZZCPPSWADO-UHFFFAOYSA-N 0.000 abstract 1
QEVHRUUCFGRFIF-SFWBKIHZSA-N Reserpine Natural products O=C(OC)[C@@H]1[C@H](OC)[C@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)C[C@H]2[C@@H]1C[C@H]1N(C2)CCc2c3c([nH]c12)cc(OC)cc3 QEVHRUUCFGRFIF-SFWBKIHZSA-N 0.000 abstract 1
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
230000016571 aggressive behavior Effects 0.000 abstract 1
230000003042 antagnostic effect Effects 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 abstract 1
125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 1
230000004899 motility Effects 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
BMXXSXQVMCXGJM-UHFFFAOYSA-N pipamperone dihydrochloride Chemical compound [Cl-].[Cl-].C1CC(C(=O)N)([NH+]2CCCCC2)CC[NH+]1CCCC(=O)C1=CC=C(F)C=C1 BMXXSXQVMCXGJM-UHFFFAOYSA-N 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 abstract 1
229960003147 reserpine Drugs 0.000 abstract 1
MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000002269 spontaneous effect Effects 0.000 abstract 1
230000001629 suppression Effects 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/20—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BE144705A 1973-05-28 1974-05-24 Nouvelles imidazolido BE815488A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP5999173A JPS5315073B2 (fr)	1973-05-28	1973-05-28

Publications (1)

Publication Number	Publication Date
BE815488A true BE815488A (fr)	1974-09-16

Family

ID=13129131

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE144705A BE815488A (fr)	1973-05-28	1974-05-24	Nouvelles imidazolido

Country Status (2)

Country	Link
JP (1)	JPS5315073B2 (fr)
BE (1)	BE815488A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU752031B2 (en) *	1998-05-08	2002-09-05	Toyama Chemical Co. Ltd.	Novel spiro compounds or salts thereof, agent for preventing and/or treating autoimmune diseases and AP-1 inhibitors containing the same

1973
- 1973-05-28 JP JP5999173A patent/JPS5315073B2/ja not_active Expired
1974
- 1974-05-24 BE BE144705A patent/BE815488A/fr unknown

Also Published As

Publication number	Publication date
JPS505392A (fr)	1975-01-21
JPS5315073B2 (fr)	1978-05-22

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