BE817823A - Procede de preparation de derives 3-iminomethyliques de la rifamycine sv - Google Patents

Procede de preparation de derives 3-iminomethyliques de la rifamycine sv

Info

Publication number: BE817823A
Authority: BE; Belgium
Prior art keywords: iminomethylic; rifamycin; derivatives; preparation; iminomethylic derivatives
Prior art date: 1973-07-25

Application number

BE146706A

Other languages

English (en)

Inventor

L Marsili

C Pasqualucci

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-07-25

Filing date

1974-07-18

Publication date

1974-11-18

1973-07-25 Priority claimed from IT2706673A external-priority patent/IT1043857B/it

1974-01-24 Priority claimed from IT1977474A external-priority patent/IT1054154B/it

1974-07-18 Application filed filed Critical

1974-11-18 Publication of BE817823A publication Critical patent/BE817823A/fr

Links

HJYYPODYNSCCOU-ODRIEIDWSA-N rifamycin SV Chemical class OC1=C(C(O)=C2C)C3=C(O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O HJYYPODYNSCCOU-ODRIEIDWSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BE146706A 1973-07-25 1974-07-18 Procede de preparation de derives 3-iminomethyliques de la rifamycine sv BE817823A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2706673A IT1043857B (it)	1973-07-25	1973-07-25	Derivati delle rifapicime procedimento della loro sintesi e loro impiego quali intermeni per la produzione di sofamicine
IT1977474A IT1054154B (it)	1974-01-24	1974-01-24	Procedimento per la preparazione di ossazino rifamione

Publications (1)

Publication Number	Publication Date
BE817823A true BE817823A (fr)	1974-11-18

Family

ID=26327298

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BE144391A BE815122A (fr)	1973-07-25	1974-05-16	Nouvelles 1,3-oxazino (5,6-c) rifamycines et procede pour leur obtention.
BE146706A BE817823A (fr)	1973-07-25	1974-07-18	Procede de preparation de derives 3-iminomethyliques de la rifamycine sv

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
BE144391A BE815122A (fr)	1973-07-25	1974-05-16	Nouvelles 1,3-oxazino (5,6-c) rifamycines et procede pour leur obtention.

Country Status (25)

Country	Link
US (3)	US3925366A (fr)
JP (2)	JPS5339440B2 (fr)
AR (2)	AR207763A1 (fr)
AT (2)	AT334530B (fr)
BE (2)	BE815122A (fr)
CA (2)	CA1024139A (fr)
CH (2)	CH611296A5 (fr)
DD (2)	DD112133A5 (fr)
DE (2)	DE2428387A1 (fr)
DK (2)	DK135286B (fr)
ES (2)	ES429060A1 (fr)
FI (2)	FI153574A7 (fr)
FR (2)	FR2257297B1 (fr)
GB (2)	GB1454802A (fr)
HU (2)	HU168723B (fr)
IE (2)	IE39388B1 (fr)
IN (2)	IN139074B (fr)
NL (2)	NL7409892A (fr)
NO (2)	NO142305C (fr)
PH (1)	PH13691A (fr)
PL (1)	PL91647B1 (fr)
RO (1)	RO63865A (fr)
SE (2)	SE393112B (fr)
SU (2)	SU613725A3 (fr)
YU (2)	YU36720B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR207763A1 (es) *	1973-07-25	1976-10-29	Archifar Ind Chim Trentino	Metodo para la preparacion de 1,3-oxacino(5,6-c)rifamicinas
GB1576886A (en) *	1977-04-20	1980-10-15	Lepetit Spa	Rifamycin derivatives
US4179439A (en) *	1977-07-01	1979-12-18	Intreprinderea De Antibiotice Iasi	Rifamycins and method for their preparation
JPS5473798A (en) *	1977-11-15	1979-06-13	Kanebo Ltd	Novel 1,3-oxazino (5,6-c) rifamycin derivative
JPS5473799A (en) *	1977-11-16	1979-06-13	Kanebo Ltd	Preparation of 1,3-oxazino (5,6-c) rifamycin derivative
GB1594134A (en) *	1977-11-25	1981-07-30	Holco Investment Inc	Rifamycins
JPS5484600A (en) *	1977-12-15	1979-07-05	Kanebo Ltd	Preparation of 1,3-oxazino 5,6-c rifamycin derivative
JPS5776597A (en) *	1980-10-30	1982-05-13	Kiyouritsu Kurieiteibu Asoshie	Electric musical instrument
JPS58115705U (ja) *	1982-02-01	1983-08-08	株式会社ニコン	カメラのフアインダ光学系
GB8308166D0 (en) *	1983-03-24	1983-05-05	Erba Farmitalia	Preparation of azinomethyl-rifamycins
GB8318072D0 (en) *	1983-07-04	1983-08-03	Lepetit Spa	Water-soluble rifampicin derivatives
US6143740A (en) *	1996-11-19	2000-11-07	Georgetown University	Heregulin antagonists and methods for their use
RU2256663C2 (ru) *	2003-07-22	2005-07-20	Гитлин Исаак Григорьевич	Способ получения 3-аминорифампицина-s (варианты)
WO2009137380A1 (fr) *	2008-05-05	2009-11-12	Janssen Pharmaceutica Nv	Dérivés de 3-hydrazone pipérazinyl-rifamycine utiles comme agents antimicrobiens
CN103755723B (zh) *	2014-02-07	2016-04-20	天津大学	一种利福平i晶型的制备方法
CN103951677B (zh) *	2014-03-17	2016-04-06	四川省长征药业股份有限公司	利福喷丁的制备方法
CN106632394A (zh) *	2016-11-15	2017-05-10	南京工业大学	一种利用釜式反应装置与微通道反应装置串联反应制备利福平的方法
CN106749326A (zh) *	2016-11-28	2017-05-31	南京工业大学	一种由利福霉素s钠盐连续生产制备利福平的方法
CN111848639A (zh) *	2020-07-09	2020-10-30	华东理工大学	一种合成利福平的工艺方法
KR102688151B1 (ko)	2021-12-28	2024-07-24	주식회사 종근당바이오	Mnp가 저감된 리팜피신의 신규 제조방법
CN119243181B (zh) *	2024-10-14	2025-10-10	河北欣港药业有限公司	一种微尺度下由利福霉素sv连续流电化学合成利福霉素s的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1090115A (en) *	1964-04-02	1967-11-08	Lepetit Spa	Mannich bases of rifamycin sv
DE1795568C3 (de) *	1964-07-31	1974-07-18	Gruppo Lepetit S.P.A., Mailand (Italien)	3-Hydroxymethyl-rifamycin SV und Verfahren zu seiner Herstellung. Ausscheidung aus: 1595883
FR208F (fr) *	1964-07-31
NL145554B (nl) *	1967-06-07	1975-04-15	Lepetit Spa	Werkwijze voor het bereiden van een 3-formylrifamycine sv-derivaat
AR207763A1 (es) *	1973-07-25	1976-10-29	Archifar Ind Chim Trentino	Metodo para la preparacion de 1,3-oxacino(5,6-c)rifamicinas

1974
- 1974-01-01 AR AR254829A patent/AR207763A1/es active
- 1974-01-01 AR AR254828A patent/AR207762A1/es active
- 1974-05-07 SE SE7406074A patent/SE393112B/xx not_active IP Right Cessation
- 1974-05-07 SE SE7406073A patent/SE407803B/xx not_active IP Right Cessation
- 1974-05-08 FR FR7415837A patent/FR2257297B1/fr not_active Expired
- 1974-05-08 GB GB2025774A patent/GB1454802A/en not_active Expired
- 1974-05-08 GB GB2025674A patent/GB1454801A/en not_active Expired
- 1974-05-09 IN IN1039/CAL/74A patent/IN139074B/en unknown
- 1974-05-09 IN IN1038/CAL/74A patent/IN138735B/en unknown
- 1974-05-14 IE IE1034/74A patent/IE39388B1/xx unknown
- 1974-05-14 YU YU1325/74A patent/YU36720B/xx unknown
- 1974-05-14 IE IE1035/74A patent/IE39389B1/xx unknown
- 1974-05-14 YU YU1324/74A patent/YU36719B/xx unknown
- 1974-05-15 NO NO741763A patent/NO142305C/no unknown
- 1974-05-15 NO NO741764A patent/NO741764L/no unknown
- 1974-05-16 BE BE144391A patent/BE815122A/fr unknown
- 1974-05-17 FI FI1535/74A patent/FI153574A7/fi unknown
- 1974-05-21 RO RO7400078880A patent/RO63865A/fr unknown
- 1974-05-23 FI FI1575/74A patent/FI60397C/fi active
- 1974-05-23 PL PL1974171342A patent/PL91647B1/pl unknown
- 1974-05-23 US US472886A patent/US3925366A/en not_active Expired - Lifetime
- 1974-05-23 US US05/472,887 patent/US3963705A/en not_active Expired - Lifetime
- 1974-05-24 CA CA200,755A patent/CA1024139A/fr not_active Expired
- 1974-05-24 DK DK284774AA patent/DK135286B/da unknown
- 1974-05-24 DK DK284874A patent/DK284874A/da unknown
- 1974-05-31 CA CA201,355A patent/CA1022548A/fr not_active Expired
- 1974-06-10 DD DD179054A patent/DD112133A5/xx unknown
- 1974-06-12 DE DE19742428387 patent/DE2428387A1/de active Pending
- 1974-06-17 PH PH15952A patent/PH13691A/en unknown
- 1974-06-17 AT AT496174A patent/AT334530B/de not_active IP Right Cessation
- 1974-07-04 JP JP7592774A patent/JPS5339440B2/ja not_active Expired
- 1974-07-04 JP JP7592874A patent/JPS5314080B2/ja not_active Expired
- 1974-07-05 SU SU2041832A patent/SU613725A3/ru active
- 1974-07-09 SU SU742040820A patent/SU576943A3/ru active
- 1974-07-10 DE DE2433105A patent/DE2433105A1/de active Granted
- 1974-07-11 DD DD179869A patent/DD112267A5/xx unknown
- 1974-07-17 FR FR7424949A patent/FR2245631B1/fr not_active Expired
- 1974-07-18 BE BE146706A patent/BE817823A/fr not_active IP Right Cessation
- 1974-07-19 AT AT596774A patent/AT334531B/de not_active IP Right Cessation
- 1974-07-22 NL NL7409892A patent/NL7409892A/xx unknown
- 1974-07-23 NL NLAANVRAGE7409955,A patent/NL181992C/xx not_active IP Right Cessation
- 1974-07-24 HU HUAI239A patent/HU168723B/hu unknown
- 1974-07-24 ES ES429060A patent/ES429060A1/es not_active Expired
- 1974-07-24 CH CH1019974A patent/CH611296A5/xx not_active IP Right Cessation
- 1974-07-24 HU HUAI240A patent/HU167983B/hu unknown
- 1974-07-24 ES ES429059A patent/ES429059A1/es not_active Expired
- 1974-07-24 CH CH1020074A patent/CH615683A5/de not_active IP Right Cessation
1983
- 1983-04-11 US US06/483,683 patent/USRE31587E/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IE39388B1 (en)	1978-09-27
DD112133A5 (fr)	1975-03-20
FR2257297B1 (fr)	1978-07-21
ES429060A1 (es)	1976-08-16
JPS5314080B2 (fr)	1978-05-15
AU6990574A (en)	1975-12-11
IE39388L (en)	1975-01-25
ATA596774A (de)	1976-05-15
FR2245631B1 (fr)	1978-09-15
BE815122A (fr)	1974-09-16
NL7409892A (nl)	1975-01-28
DE2433105C2 (fr)	1988-03-31
AT334531B (de)	1976-01-25
HU167983B (fr)	1976-02-28
IN139074B (fr)	1976-05-01
CH615683A5 (fr)	1980-02-15
IE39389B1 (en)	1978-09-27
ATA496174A (de)	1976-05-15
PH13691A (en)	1980-09-01
SE7406073L (fr)	1975-01-27
GB1454802A (en)	1976-11-03
JPS5339440B2 (fr)	1978-10-21
HU168723B (fr)	1976-07-28
DK135286B (da)	1977-03-28
DE2433105A1 (de)	1975-02-06
NO741763L (fr)	1975-02-24
AT334530B (de)	1976-01-25
IE39389L (en)	1975-01-25
SE7406074L (fr)	1975-01-27
DK284874A (da)	1975-01-26
ES429059A1 (es)	1976-08-16
JPS5042021A (fr)	1975-04-16
YU36719B (en)	1984-08-31
FR2245631A1 (fr)	1975-04-25
FI60397B (fi)	1981-09-30
IN138735B (fr)	1976-03-27
SE407803B (sv)	1979-04-23
NL181992C (nl)	1987-12-16
JPS5041897A (fr)	1975-04-16
DK135286C (fr)	1977-09-05
CH611296A5 (fr)	1979-05-31
NO741764L (fr)	1975-02-24
YU132474A (en)	1981-11-13
FI60397C (fi)	1982-01-11
YU132574A (en)	1981-11-13
NO142305C (no)	1980-07-30
NL181992B (nl)	1987-07-16
SE393112B (sv)	1977-05-02
SU613725A3 (ru)	1978-06-30
CA1024139A (fr)	1978-01-10
AR207762A1 (es)	1976-10-29
FI153574A7 (fr)	1975-01-26
GB1454801A (en)	1976-11-03
SU576943A3 (ru)	1977-10-15
CA1022548A (fr)	1977-12-13
DD112267A5 (fr)	1975-04-05
US3963705A (en)	1976-06-15
SU613725A1 (fr)	1978-06-30
RO63865A (fr)	1979-01-15
FI157574A7 (fr)	1975-01-26
DK284774A (fr)	1975-01-26
FR2257297A1 (fr)	1975-08-08
NL7409955A (nl)	1975-01-28
USRE31587E (en)	1984-05-22
NO142305B (no)	1980-04-21
YU36720B (en)	1984-08-31
US3925366A (en)	1975-12-09
AR207763A1 (es)	1976-10-29
PL91647B1 (fr)	1977-03-31
DE2428387A1 (de)	1975-02-13
AU6991074A (en)	1975-12-11

Legal Events

Date

Code

Title

Description

1994-01-31

RE

Patent lapsed

Owner name: GRUPPO LEPETIT S.P.A.

Effective date: 19930731

Publication	Publication Date	Title
BE817823A (fr)	1974-11-18	Procede de preparation de derives 3-iminomethyliques de la rifamycine sv
RO66907A (fr)	1981-06-26	Procede pour la preparation des derives 2-acyle-4-oxypyrazinoisoquinoline
BE811754A (fr)	1974-09-02	Procede de preparation de derives du 1-phenyl-2-aminoethanol
BE821760A (fr)	1975-04-30	Procede de preparation de derives 7-amino-delta3-cephem
BE811521A (fr)	1974-08-26	Procede de preparation de derives d'acides 7-acylamino-desacetoxy cephalosporaniques
BE822566A (fr)	1975-05-26	Procede de preparation de phenylhydroxylamines chlorees
BE811172A (fr)	1974-08-19	Procede de preparation de composes n
BE817168A (fr)	1975-01-02	Procede de preparation de derives de la quinoleine
FR2303014A1 (fr)	1976-10-01	Procede de preparation de derives de 4-oxo-hexahydro-pyrazino-isoquinoleine
FR2300755A1 (fr)	1976-09-10	Procede de preparation de derives de beta-dihalogenoethenylcyclopropane
RO64480A (fr)	1979-05-15	Procede de preparation de la pyridinecarboxamidosulfoniluree
AR208187A1 (es)	1976-12-09	Metodo para la preparacion derivados de n-carbamoil-2-feniletensulfonamida
FR2277077A1 (fr)	1976-01-30	Procede de preparation de derives de phenylisopropyluree
BE820475A (fr)	1975-01-16	Procede de preparation de 6-demethyl-6-desoxy-6-methylene-tetracyclines
BE816708A (fr)	1974-12-23	Procede de preparation de derives de dicycloalkane
BE816374A (fr)	1974-12-16	Procede de preparation de derives antibiotiques
RO69155A (fr)	1981-03-30	Procede pour la preparation des derives de 1-phenoxy-3-aminopropane-2-ole
BE844414A (fr)	1977-01-24	Procede de preparation de derives de la quinoleine
BE818579A (fr)	1975-02-07	Procede de preparation de derives de propanolamine
RO70535A (fr)	1981-08-17	Procede pour la preparation des derives du 3-aminopyprole
BG25231A3 (bg)	1978-08-10	Метод за получаване на производни на рифамицин sv
PT65041B (fr)	1977-09-12	Procede de preparation de derives de la thieno-pyridine
BE821529A (fr)	1975-04-28	Procede de preparation de derives de 1h-tetrazole-5-thiol
BE806255A (fr)	1974-04-18	Procede de preparation de derives de la morphanthridinone
BE823838A (fr)	1975-04-16	Procede pour la preparation de derives de tricyclohexyletain