BE841870A - Preparation stable d'insuline - Google Patents

Preparation stable d'insuline

Info

Publication number: BE841870A
Authority: BE; Belgium
Prior art keywords: insulin preparation; stable insulin; stable; preparation; insulin
Prior art date: 1975-06-13

Application number

BE167069A

Other languages

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-06-13

Filing date

1976-05-14

Publication date

1976-11-16

1976-05-14 Application filed filed Critical

1976-11-16 Publication of BE841870A publication Critical patent/BE841870A/fr

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
102000004877 Insulin Human genes 0.000 title 1
108090001061 Insulin Proteins 0.000 title 1
229940125396 insulin Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Oil, Petroleum & Natural Gas (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Endocrinology (AREA)
Immunology (AREA)
Diabetes (AREA)
Otolaryngology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BE167069A 1975-06-13 1976-05-14 Preparation stable d'insuline BE841870A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2535175A GB1554157A (en)	1975-06-13	1975-06-13	Stable insulin preparation for intra nasal administration

Publications (1)

Publication Number	Publication Date
BE841870A true BE841870A (fr)	1976-11-16

Family

ID=10226264

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE167069A BE841870A (fr)	1975-06-13	1976-05-14	Preparation stable d'insuline

Country Status (5)

Country	Link
JP (1)	JPS51148013A (fr)
BE (1)	BE841870A (fr)
DE (1)	DE2620483A1 (fr)
FR (1)	FR2313914A1 (fr)
GB (1)	GB1554157A (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2917535C2 (de) *	1979-04-30	1986-10-30	Hoechst Ag, 6230 Frankfurt	Gegen Denaturierung beständige Insulinlösungen
US4783441A (en) *	1979-04-30	1988-11-08	Hoechst Aktiengesellschaft	Aqueous protein solutions stable to denaturation
EP0018609B1 (fr) *	1979-04-30	1983-09-21	Hoechst Aktiengesellschaft	Solutions aqueuses de protéines, stables à la dénaturation, procédé pour leur fabrication et leur utilisation
AU558474B2 (en) *	1981-07-17	1987-01-29	Nordisk Insulinlaboratorium	A stable aqueous, therapeutic insulin preparation and a process for preparing it
DE3443877A1 (de) *	1984-06-09	1985-12-12	Hoechst Ag	Insulinzubereitungen, verfahren zu deren herstellung und deren verwendung
JPS61267528A (ja) *	1984-11-26	1986-11-27	Yamanouchi Pharmaceut Co Ltd	吸収促進剤を含有するカルシトニン経鼻剤
EP0200383A3 (fr) *	1985-04-15	1987-09-02	Eli Lilly And Company	Procédé pour administrer l'insuline
DK179286D0 (da) *	1986-04-18	1986-04-18	Nordisk Gentofte	Insulinpraeparat
CA1291036C (fr) *	1986-04-23	1991-10-22	Edwin I. Stoltz	Administration de medicaments par voie nasale
ES2045276T3 (es) *	1988-07-21	1994-01-16	Hoffmann La Roche	Preparacion de insulina
AU7880991A (en) *	1990-05-10	1991-11-27	Novo Nordisk A/S	A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols
US6524557B1 (en)	1994-12-22	2003-02-25	Astrazeneca Ab	Aerosol formulations of peptides and proteins
WO1996019198A1 (fr)	1994-12-22	1996-06-27	Astra Aktiebolag	Preparations medicamenteuses aerosols
DE10227232A1 (de) *	2002-06-18	2004-01-15	Aventis Pharma Deutschland Gmbh	Saure Insulinzubereitungen mit verbesserter Stabilität
KR100978717B1 (ko) *	2003-12-08	2010-08-30	씨펙스 파마슈티칼스, 인코포레이티드	인슐린 치료를 위한 약제 조성물 및 방법
US7851419B2 (en) *	2005-09-12	2010-12-14	Nawaz Ahmad	Substantially anhydrous sprayable personal lubricant
PT3228320T (pt)	2008-10-17	2020-03-26	Sanofi Aventis Deutschland	Combinação de uma insulina e de um agonista do glp-1
KR101853606B1 (ko)	2009-07-06	2018-05-03	사노피-아벤티스 도이칠란트 게엠베하	메티오닌을 함유하는 수성 인슐린 제제
KR101337322B1 (ko)	2009-11-13	2013-12-06	사노피-아벤티스 도이칠란트 게엠베하	Ｇｌｐ-1 효능제 및 메티오닌을 포함하는 약제학적 조성물
DK2498802T3 (en)	2009-11-13	2015-04-13	Sanofi Aventis Deutschland	Pharmaceutical composition comprising a GLP-1 agonist, insulin and a methionine
ES2606554T3 (es)	2010-08-30	2017-03-24	Sanofi-Aventis Deutschland Gmbh	Uso de AVE0010 para la fabricación de un medicamento para el tratamiento de la diabetes mellitus de tipo 2
US9821032B2 (en)	2011-05-13	2017-11-21	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
ITRM20110390A1 (it)	2011-07-21	2013-01-22	Eramo Alessandra D	Prodotto per stimolare la produzione endogena di mediatori dell'infiammazione.
PL2750699T3 (pl)	2011-08-29	2015-12-31	Sanofi Aventis Deutschland	Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
AR087744A1 (es)	2011-09-01	2014-04-16	Sanofi Aventis Deutschland	Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
EP3030294B1 (fr) *	2013-08-05	2020-10-07	MannKind Corporation	Appareil d'insufflation
AU2015359376B2 (en)	2014-12-12	2021-09-09	Sanofi-Aventis Deutschland Gmbh	Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh)	2015-03-13	2021-12-11	德商賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患治療
TW201705975A (zh)	2015-03-18	2017-02-16	賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患之治療

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL62232C (fr) *		1900-01-01
US3096249A (en) *	1960-05-10	1963-07-02	Samuel J Prigal	Emulsion composition

1975
- 1975-06-13 GB GB2535175A patent/GB1554157A/en not_active Expired
1976
- 1976-05-08 DE DE19762620483 patent/DE2620483A1/de not_active Withdrawn
- 1976-05-13 JP JP5493176A patent/JPS51148013A/ja active Pending
- 1976-05-14 FR FR7614706A patent/FR2313914A1/fr active Granted
- 1976-05-14 BE BE167069A patent/BE841870A/fr not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE2620483A1 (de)	1976-12-23
FR2313914B1 (fr)	1979-04-13
GB1554157A (en)	1979-10-17
FR2313914A1 (fr)	1977-01-07
JPS51148013A (en)	1976-12-18

Legal Events

Date

Code

Title

Description

1986-11-30

RE

Patent lapsed

Owner name: TAKEDA CHEMICAL INDUSTRIES LTD

Effective date: 19860531

Publication	Publication Date	Title
BE841871A (fr)	1976-11-16	Nouvelle preparation d'insuline
HU174805B (hu)	1980-03-28	Sposob poluchenija katalizatorov dlja polimerizacii al'fa-olefinov
HU175109B (hu)	1980-05-28	Sposob poluchenija novykh benzgidril-sul'finilovykh proizvodnykh
HU171030B (hu)	1977-10-28	Sposob poluchenija novykh oksim-ehfirnykh soedinenij s antidepressivnoj aktivnost'ju
FR2326941A1 (fr)	1977-05-06	Aiguille d'hemodialyse
FI800518A7 (fi)	1980-08-23	Anordning foer kontinuerlig infusion
BE827626A (fr)	1975-10-07	Serinque d'injection
HU173209B (hu)	1979-03-28	Soedinitel' k trubam
DK348079A (da)	1980-02-22	Administrationsform
BE860187A (fr)	1978-02-15	Capuchon d'aiguille perfectionne
NZ179733A (en)	1978-04-28	Stable insulin preparation
BE838480A (fr)	1976-05-28	Seringe d'injection
FR2351972A1 (fr)	1977-12-16	Precurseurs d'acides heteroarylbenzoxepine-acetiques
HU172533B (hu)	1978-09-28	Sposob poluchenija tvjordykh rastvorov alkaloidov sporyn'i i ikh proizvodnykh
SE7711395L (sv)	1978-04-13	Farmaceutisk komposition
HU171875B (hu)	1978-04-28	Dvigatel' vnutrennego sgoranija s kompressionnym zazhiganiem
FR2330926A1 (fr)	1977-06-03	Elements d'etancheite
HU171805B (hu)	1978-03-28	Sposob poluchenija 1-skobka-p-metilsul'finil-benziliden-skobka zakryta-2-metil-5-ftoro-indenil-3-uksusnojj kisloty
DK39079A (da)	1979-12-01	Stabilt praeparat
FR2305977A1 (fr)	1976-10-29	Solution parenterale d'amino-acides
HU172924B (hu)	1979-01-28	Sposob poluchenija proizvodnykh rifamicina s bol'shojj aktivnosti
FR2314732A1 (fr)	1977-01-14	Solution d'iodophore
HU171514B (hu)	1978-01-28	Sposob poluchenija stabil'nykh rastvorov gidrirovannykh alkaloidov sporyn'i
BE843183A (fr)	1976-12-20	Solution d'iodophores
SE7707498L (sv)	1978-01-23	Vermeherdbar hartskomposition