BE841870A - Preparation stable d'insuline - Google Patents

Preparation stable d'insuline

Info

Publication number: BE841870A
Authority: BE; Belgium
Prior art keywords: insulin preparation; stable insulin; stable; preparation; insulin
Prior art date: 1975-06-13

Application number

BE167069A

Other languages

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-06-13

Filing date

1976-05-14

Publication date

1976-11-16

1976-05-14 Application filed filed Critical

1976-11-16 Publication of BE841870A publication Critical patent/BE841870A/fr

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
102000004877 Insulin Human genes 0.000 title 1
108090001061 Insulin Proteins 0.000 title 1
229940125396 insulin Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Zoology (AREA)
Biochemistry (AREA)
Otolaryngology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BE167069A 1975-06-13 1976-05-14 Preparation stable d'insuline BE841870A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2535175A GB1554157A (en)	1975-06-13	1975-06-13	Stable insulin preparation for intra nasal administration

Publications (1)

Publication Number	Publication Date
BE841870A true BE841870A (fr)	1976-11-16

Family

ID=10226264

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE167069A BE841870A (fr)	1975-06-13	1976-05-14	Preparation stable d'insuline

Country Status (5)

Country	Link
JP (1)	JPS51148013A (fr)
BE (1)	BE841870A (fr)
DE (1)	DE2620483A1 (fr)
FR (1)	FR2313914A1 (fr)
GB (1)	GB1554157A (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3064888D1 (en) *	1979-04-30	1983-10-27	Hoechst Ag	Aqueous solutions of proteins stable against denaturization, process for their manufacture, and their utilization
US4783441A (en) *	1979-04-30	1988-11-08	Hoechst Aktiengesellschaft	Aqueous protein solutions stable to denaturation
DE2917535C2 (de) *	1979-04-30	1986-10-30	Hoechst Ag, 6230 Frankfurt	Gegen Denaturierung beständige Insulinlösungen
EP0083619A1 (fr) *	1981-07-17	1983-07-20	Nordisk Insulinlaboratorium	Preparation therapeutique d'insuline aqueuse stable et son procede de preparation
DE3443877A1 (de) *	1984-06-09	1985-12-12	Hoechst Ag	Insulinzubereitungen, verfahren zu deren herstellung und deren verwendung
JPS61267528A (ja) *	1984-11-26	1986-11-27	Yamanouchi Pharmaceut Co Ltd	吸収促進剤を含有するカルシトニン経鼻剤
EP0200383A3 (fr) *	1985-04-15	1987-09-02	Eli Lilly And Company	Procédé pour administrer l'insuline
DK179286D0 (da) *	1986-04-18	1986-04-18	Nordisk Gentofte	Insulinpraeparat
CA1291036C (fr) *	1986-04-23	1991-10-22	Edwin I. Stoltz	Administration de medicaments par voie nasale
EP0351651B1 (fr) *	1988-07-21	1993-09-15	F. Hoffmann-La Roche Ag	Préparation à base d'insuline
JP3219096B2 (ja) *	1990-05-10	2001-10-15	ニコメドファーマエイエス	ｎ―グリコフロール類及びｎ―エチレングリコール類を含有する医薬製剤
US6524557B1 (en)	1994-12-22	2003-02-25	Astrazeneca Ab	Aerosol formulations of peptides and proteins
CN1088580C (zh)	1994-12-22	2002-08-07	阿斯特拉公司	气溶胶药物制剂
DE10227232A1 (de) *	2002-06-18	2004-01-15	Aventis Pharma Deutschland Gmbh	Saure Insulinzubereitungen mit verbesserter Stabilität
EA010885B1 (ru) *	2003-12-08	2008-12-30	Бентли Фармасьютикалз, Инк.	Фармацевтические композиции и способы лечения инсулином
US7851419B2 (en) *	2005-09-12	2010-12-14	Nawaz Ahmad	Substantially anhydrous sprayable personal lubricant
EP3228320B1 (fr)	2008-10-17	2019-12-18	Sanofi-Aventis Deutschland GmbH	Combinaison d'une insuline et d'un antagoniste glp 1
EP3202394A1 (fr)	2009-07-06	2017-08-09	Sanofi-Aventis Deutschland GmbH	Préparations aqueuses de l´insuline contenant de la méthionine
PT2554183T (pt)	2009-11-13	2018-07-09	Sanofi Aventis Deutschland	Composição farmacêutica que compreende um agonista de glp-1, uma insulina e metionina
PE20121316A1 (es)	2009-11-13	2012-10-05	Sanofi Aventis Deutschland	Composicion farmaceutica que comprende un agonista de glp-1 y metionina
US20140148384A1 (en)	2010-08-30	2014-05-29	Sanofi-Aventis Deutschland Gmbh	Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
US9821032B2 (en)	2011-05-13	2017-11-21	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
ITRM20110390A1 (it) *	2011-07-21	2013-01-22	Eramo Alessandra D	Prodotto per stimolare la produzione endogena di mediatori dell'infiammazione.
CN108079281A (zh)	2011-08-29	2018-05-29	赛诺菲-安万特德国有限公司	用于2型糖尿病患者中的血糖控制的药物组合
TWI559929B (en)	2011-09-01	2016-12-01	Sanofi Aventis Deutschland	Pharmaceutical composition for use in the treatment of a neurodegenerative disease
EP3030294B1 (fr) *	2013-08-05	2020-10-07	MannKind Corporation	Appareil d'insufflation
TWI758239B (zh)	2014-12-12	2022-03-21	德商賽諾菲阿凡提斯德意志有限公司	甘精胰島素/利司那肽固定比率配製劑
TWI748945B (zh)	2015-03-13	2021-12-11	德商賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患治療
TW201705975A (zh)	2015-03-18	2017-02-16	賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患之治療

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL62232C (fr) *		1900-01-01
US3096249A (en) *	1960-05-10	1963-07-02	Samuel J Prigal	Emulsion composition

1975
- 1975-06-13 GB GB2535175A patent/GB1554157A/en not_active Expired
1976
- 1976-05-08 DE DE19762620483 patent/DE2620483A1/de not_active Withdrawn
- 1976-05-13 JP JP5493176A patent/JPS51148013A/ja active Pending
- 1976-05-14 BE BE167069A patent/BE841870A/fr not_active IP Right Cessation
- 1976-05-14 FR FR7614706A patent/FR2313914A1/fr active Granted

Also Published As

Publication number	Publication date
DE2620483A1 (de)	1976-12-23
FR2313914B1 (fr)	1979-04-13
JPS51148013A (en)	1976-12-18
GB1554157A (en)	1979-10-17
FR2313914A1 (fr)	1977-01-07

Legal Events

Date

Code

Title

Description

1986-11-30

RE

Patent lapsed

Owner name: TAKEDA CHEMICAL INDUSTRIES LTD

Effective date: 19860531

Publication	Publication Date	Title
BE841870A (fr)	1976-11-16	Preparation stable d'insuline
BE841871A (fr)	1976-11-16	Nouvelle preparation d'insuline
HU174805B (hu)	1980-03-28	Sposob poluchenija katalizatorov dlja polimerizacii al'fa-olefinov
HU175109B (hu)	1980-05-28	Sposob poluchenija novykh benzgidril-sul'finilovykh proizvodnykh
HU171030B (hu)	1977-10-28	Sposob poluchenija novykh oksim-ehfirnykh soedinenij s antidepressivnoj aktivnost'ju
FR2326941A1 (fr)	1977-05-06	Aiguille d'hemodialyse
FI800518A7 (fi)	1980-08-23	Anordning foer kontinuerlig infusion
BE827626A (fr)	1975-10-07	Serinque d'injection
HU173209B (hu)	1979-03-28	Soedinitel' k trubam
DK348079A (da)	1980-02-22	Administrationsform
BE860187A (fr)	1978-02-15	Capuchon d'aiguille perfectionne
NZ179733A (en)	1978-04-28	Stable insulin preparation
FR2332766A1 (fr)	1977-06-24	Seringue d'injection
FR2351972A1 (fr)	1977-12-16	Precurseurs d'acides heteroarylbenzoxepine-acetiques
HU172533B (hu)	1978-09-28	Sposob poluchenija tvjordykh rastvorov alkaloidov sporyn'i i ikh proizvodnykh
SE7711395L (sv)	1978-04-13	Farmaceutisk komposition
HU171875B (hu)	1978-04-28	Dvigatel' vnutrennego sgoranija s kompressionnym zazhiganiem
FR2330926A1 (fr)	1977-06-03	Elements d'etancheite
HU171805B (hu)	1978-03-28	Sposob poluchenija 1-skobka-p-metilsul'finil-benziliden-skobka zakryta-2-metil-5-ftoro-indenil-3-uksusnojj kisloty
DK39079A (da)	1979-12-01	Stabilt praeparat
BE840227A (fr)	1976-07-16	Solution parenterale d'amino-acides
HU172924B (hu)	1979-01-28	Sposob poluchenija proizvodnykh rifamicina s bol'shojj aktivnosti
FR2314732A1 (fr)	1977-01-14	Solution d'iodophore
HU171514B (hu)	1978-01-28	Sposob poluchenija stabil'nykh rastvorov gidrirovannykh alkaloidov sporyn'i
BE843183A (fr)	1976-12-20	Solution d'iodophores