BE843412A - Tetrahydroisoquinoleines substituees, procede pour les preparer et compositions pharmaceutiques les contenant - Google Patents

Tetrahydroisoquinoleines substituees, procede pour les preparer et compositions pharmaceutiques les contenant

Info

Publication number
BE843412A
BE843412A BE168314A BE168314A BE843412A BE 843412 A BE843412 A BE 843412A BE 168314 A BE168314 A BE 168314A BE 168314 A BE168314 A BE 168314A BE 843412 A BE843412 A BE 843412A
Authority
BE
Belgium
Prior art keywords
tetrahydroisoquinoleins
substituted
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
BE168314A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/590,772 external-priority patent/US3988339A/en
Application filed filed Critical
Publication of BE843412A publication Critical patent/BE843412A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/298—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • C07C45/43—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis of >CX2 groups, X being halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
BE168314A 1975-06-26 1976-06-25 Tetrahydroisoquinoleines substituees, procede pour les preparer et compositions pharmaceutiques les contenant BE843412A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/590,772 US3988339A (en) 1974-02-08 1975-06-26 Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase

Publications (1)

Publication Number Publication Date
BE843412A true BE843412A (fr) 1976-12-27

Family

ID=24363639

Family Applications (1)

Application Number Title Priority Date Filing Date
BE168314A BE843412A (fr) 1975-06-26 1976-06-25 Tetrahydroisoquinoleines substituees, procede pour les preparer et compositions pharmaceutiques les contenant

Country Status (12)

Country Link
US (1) US4062961A (fr)
JP (1) JPS527445A (fr)
AU (1) AU499217B2 (fr)
BE (1) BE843412A (fr)
CA (1) CA1069440A (fr)
DE (1) DE2628425A1 (fr)
FR (1) FR2315276A1 (fr)
GB (1) GB1561583A (fr)
IE (1) IE43794B1 (fr)
IL (1) IL49897A (fr)
NL (1) NL7606960A (fr)
ZA (1) ZA763806B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258049A (en) * 1979-07-02 1981-03-24 Smithkline Corporation Inhibiting phenylethanolamine N-methyltransferase with thiadiazolo and oxadiazolotetrahydroisoquinolines
US4340600A (en) * 1980-05-22 1982-07-20 Smithkline Corporation Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988339A (en) * 1974-02-08 1976-10-26 Smithkline Corporation Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase

Also Published As

Publication number Publication date
US4062961A (en) 1977-12-13
AU499217B2 (en) 1979-04-12
FR2315276A1 (fr) 1977-01-21
ZA763806B (en) 1977-05-25
AU1532376A (en) 1978-01-05
NL7606960A (nl) 1976-12-28
DE2628425A1 (de) 1977-01-20
FR2315276B1 (fr) 1980-03-14
IL49897A (en) 1979-09-30
JPS527445A (en) 1977-01-20
IE43794L (en) 1976-12-26
IE43794B1 (en) 1981-06-03
CA1069440A (fr) 1980-01-08
IL49897A0 (en) 1976-08-31
GB1561583A (en) 1980-02-27

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SMITHKLINE BECKMAN CORP.

Effective date: 19870630