BE844452A - Granules et comprimes d'acide l-ascorbique et procede pour les preparer - Google Patents
Granules et comprimes d'acide l-ascorbique et procede pour les preparerInfo
- Publication number
- BE844452A BE844452A BE169176A BE169176A BE844452A BE 844452 A BE844452 A BE 844452A BE 169176 A BE169176 A BE 169176A BE 169176 A BE169176 A BE 169176A BE 844452 A BE844452 A BE 844452A
- Authority
- BE
- Belgium
- Prior art keywords
- tablets
- preparing
- ascorbic acid
- acid granules
- granules
- Prior art date
Links
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 title 2
- 239000002211 L-ascorbic acid Substances 0.000 title 1
- 235000000069 L-ascorbic acid Nutrition 0.000 title 1
- 229960005070 ascorbic acid Drugs 0.000 title 1
- 239000008187 granular material Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50090742A JPS58403B2 (ja) | 1975-07-24 | 1975-07-24 | L− アスコルビンサンセイザイノ セイゾウホウ |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE844452A true BE844452A (fr) | 1977-01-24 |
Family
ID=14007025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE169176A BE844452A (fr) | 1975-07-24 | 1976-07-23 | Granules et comprimes d'acide l-ascorbique et procede pour les preparer |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US4036948A (fr) |
| JP (1) | JPS58403B2 (fr) |
| BE (1) | BE844452A (fr) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2706660A1 (de) * | 1977-02-17 | 1978-08-24 | Merck Patent Gmbh | Ascorbinsaeure enthaltende granulate und verfahren zu ihrer herstellung |
| GB2058562B (en) * | 1979-09-14 | 1983-11-30 | Beecham Group Ltd | Pharmaceutical compositions containing paracetamol and ascorbic acid |
| JPS5759803A (en) * | 1980-09-30 | 1982-04-10 | Takeda Chem Ind Ltd | Granule of l-sodium ascorbate, its preparation, and tablet comprising it |
| JPS5970614A (ja) * | 1982-10-14 | 1984-04-21 | Asahi Chem Ind Co Ltd | 微量主薬系湿式固形製剤方法 |
| US4495177A (en) * | 1983-01-17 | 1985-01-22 | Shaklee Corporation | Gel tableting agent |
| US4533674A (en) * | 1983-10-24 | 1985-08-06 | Basf Wyandotte Corporation | Process for preparing a sugar and starch free spray-dried vitamin C powder containing 90 percent ascorbic acid |
| US4605666A (en) * | 1983-10-24 | 1986-08-12 | Basf Corporation | Process for preparing spray-dried powders containing a water-soluble vitamin and powders prepared thereby |
| JPS61500435A (ja) * | 1983-10-24 | 1986-03-13 | バスフ・コーポレーション | 水溶性ビタミンを含有する噴霧乾燥された粉末及びこの方法により製造された粉末 |
| US4618487A (en) * | 1984-07-06 | 1986-10-21 | Alza Corporation | Device for administering calcium ascorbate |
| JPH0753663B2 (ja) * | 1984-10-09 | 1995-06-07 | 武田薬品工業株式会社 | チアミン塩の顆粒,その製造法および錠剤 |
| DE3447422A1 (de) * | 1984-12-24 | 1986-06-26 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von ascorbinsaeure-granulat |
| US4710519A (en) * | 1985-09-30 | 1987-12-01 | Basf Corporation | Process for preparing spray dried acetaminophen powder and the powder prepared thereby |
| AU587863B2 (en) * | 1985-10-07 | 1989-08-31 | Basf Aktiengesellschaft | Vitamin-containing granules and production thereof |
| US5624683A (en) * | 1986-08-06 | 1997-04-29 | Eisai Co., Ltd. | Sustained-release multi-granule tablet |
| US4837031A (en) * | 1987-09-17 | 1989-06-06 | Mallinckrodt, Inc. | Compositions containing ibuprofen |
| US4837033A (en) * | 1987-12-22 | 1989-06-06 | Shin-Etsu Chemical Co., Ltd. | Method for the preparation of a coated solid medicament |
| JP2689458B2 (ja) * | 1988-02-09 | 1997-12-10 | 武田薬品工業株式会社 | 粒状ないし粉末状のビタミンb▲下1▼▲下2▼類含有組成物 |
| AU1193092A (en) * | 1992-01-10 | 1993-08-03 | Obschestvo S Ogranichennoi Otvetstvennostju Meditsinsky Nauchno-Proizvodstvenny Komplex Biotiki | Granulated pharmaceutical composition and method of obtaining it |
| ES2096103T3 (es) * | 1992-01-13 | 1997-03-01 | Pfizer | Preparacion de comprimidos de resistencia incrementada. |
| US5837292A (en) * | 1996-07-03 | 1998-11-17 | Yamanouchi Europe B.V. | Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug |
| JP4098376B2 (ja) * | 1996-09-05 | 2008-06-11 | ビーエーエスエフ ソシエタス・ヨーロピア | 錠剤特性の優れた水溶性ビタミン組成物およびその製造法 |
| WO1999017746A1 (fr) * | 1997-10-07 | 1999-04-15 | Eisai Co., Ltd. | Procede de preparation de poudre emulsionnee |
| US6299889B1 (en) | 1998-09-10 | 2001-10-09 | Avon Products, Inc. | Stable ascorbic acid preparation for topical use |
| US6294198B1 (en) * | 1999-08-24 | 2001-09-25 | Purepac Pharmaceutical Co. | Pharmaceutical tablet formulation containing gabapentin with improved physical and chemical characteristics and method of making the same |
| US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
| PE20040134A1 (es) * | 2002-07-25 | 2004-03-06 | Pharmacia Corp | Forma de dosificacion de una vez al dia de pramipexol |
| MY136318A (en) * | 2002-07-25 | 2008-09-30 | Pharmacia Corp | Sustained-release tablet composition |
| TW200517114A (en) | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| NZ553645A (en) * | 2004-08-13 | 2010-09-30 | Boehringer Ingelheim Int | Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof |
| NZ553561A (en) * | 2004-08-13 | 2010-12-24 | Boehringer Ingelheim Int | Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof |
| CN100431515C (zh) * | 2005-05-24 | 2008-11-12 | 浙江大学 | 稳定微粒化药物添加剂的制备方法 |
| US20090041844A1 (en) * | 2006-02-10 | 2009-02-12 | Boehringer Ingelheim International Gmbh | Modified Release Formulation |
| US20090098202A1 (en) * | 2006-02-10 | 2009-04-16 | Boehringer Ingelheim International Gmbh | Extended Release Formulation |
| WO2008031886A1 (fr) * | 2006-09-15 | 2008-03-20 | Basf Se | Procédé de préparation de granulés de vitamine hydrophile |
| WO2008135297A1 (fr) * | 2007-05-08 | 2008-11-13 | Basf Se | Procédé pour produire des granulés de vitamines solubles dans l'eau |
| US9901551B2 (en) | 2009-04-20 | 2018-02-27 | Ambra Bioscience Llc | Chemosensory receptor ligand-based therapies |
| BRPI1013856A2 (pt) | 2009-04-20 | 2016-04-05 | Elcelyx Therapeutics Inc | terapias à base de ligantes de receptores quimiossensíveis |
| US8828953B2 (en) * | 2009-04-20 | 2014-09-09 | NaZura BioHealth, Inc. | Chemosensory receptor ligand-based therapies |
| JP5733930B2 (ja) * | 2009-09-09 | 2015-06-10 | 武田薬品工業株式会社 | 固形製剤 |
| FR2953458B1 (fr) * | 2009-12-09 | 2012-01-13 | Michelin Soc Tech | Bourrelet de pneumatique pour vehicule lourd de type genie civil |
| WO2012054523A2 (fr) | 2010-10-19 | 2012-04-26 | Elcelyx Therapeutics, Inc. | Thérapies basées sur un ligand de récepteur chimiosensoriel |
| LT2661266T (lt) | 2011-01-07 | 2020-12-10 | Anji Pharma (Us) Llc | Gydimo būdai chemosensorinio receptoriaus ligando pagrindu |
| US9795792B2 (en) | 2011-02-25 | 2017-10-24 | Medtronic, Inc. | Emergency mode switching for non-pacing modes |
| CN104254325A (zh) | 2012-01-06 | 2014-12-31 | 埃尔舍利克斯治疗公司 | 双胍组合物和治疗代谢性病症的方法 |
| CN110693867A (zh) | 2012-01-06 | 2020-01-17 | 埃尔舍利克斯治疗公司 | 用于治疗代谢性病症的组合物和方法 |
| WO2013158928A2 (fr) | 2012-04-18 | 2013-10-24 | Elcelyx Therapeutics, Inc. | Thérapies à base de ligand de récepteur chimiosensoriels |
| CA2878625A1 (fr) | 2012-07-11 | 2014-01-16 | Elcelyx Therapeutics, Inc. | Compositions comportant des statines, des biguanides et d'autres agents pour reduire un risque cardiometabolique |
| HK1214966A1 (zh) | 2013-01-05 | 2016-08-12 | Anji Pharmaceuticals Inc. | 包含雙胍的延遲釋放組合物 |
| CA3107875A1 (fr) | 2017-09-15 | 2019-03-21 | Home Tech Innovation, Inc. | Appareil et procedes pour le stockage et la cuisson de repas au moins semi-autonomes |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2980589A (en) * | 1958-09-12 | 1961-04-18 | American Cyanamid Co | Process for producing anhydrous granulation of a medicinally active waterlabile powder |
| US3084104A (en) * | 1961-06-28 | 1963-04-02 | Richardson Merrell Inc | Process of preparing granulation of medicinal agents |
| US3873713A (en) * | 1967-06-30 | 1975-03-25 | Hoffmann La Roche | Stabilized particulate vitamin c composition |
| US3584114A (en) * | 1968-05-22 | 1971-06-08 | Hoffmann La Roche | Free-flowing powders |
| US3639168A (en) * | 1969-04-29 | 1972-02-01 | Sucrest Corp | Direct compression vehicles |
-
1975
- 1975-07-24 JP JP50090742A patent/JPS58403B2/ja not_active Expired
- 1975-09-03 US US05/610,003 patent/US4036948A/en not_active Expired - Lifetime
-
1976
- 1976-07-23 BE BE169176A patent/BE844452A/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US4036948A (en) | 1977-07-19 |
| JPS58403B2 (ja) | 1983-01-06 |
| JPS5215812A (en) | 1977-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE20 | Patent expired |
Owner name: TAKEDA CHEMICAL INDUSTRIES LTD Effective date: 19960723 |