BE850204A - Analogues nouveaux de prostaglandines - Google Patents

Analogues nouveaux de prostaglandines

Info

Publication number
BE850204A
BE850204A BE173933A BE173933A BE850204A BE 850204 A BE850204 A BE 850204A BE 173933 A BE173933 A BE 173933A BE 173933 A BE173933 A BE 173933A BE 850204 A BE850204 A BE 850204A
Authority
BE
Belgium
Prior art keywords
prostaglandins
new analogues
analogues
new
Prior art date
Application number
BE173933A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BE850204A publication Critical patent/BE850204A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056—Esters of arylalkanephosphonic acids
    • C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE173933A 1976-01-08 1977-01-07 Analogues nouveaux de prostaglandines BE850204A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/647,357 US4055602A (en) 1976-01-08 1976-01-08 2-Decarboxy-2-hydroxy-methyl-5-oxa-17-phenyl-18,19,20-trinor-PGF-analogs

Publications (1)

Publication Number Publication Date
BE850204A true BE850204A (fr) 1977-07-07

Family

ID=24596656

Family Applications (1)

Application Number Title Priority Date Filing Date
BE173933A BE850204A (fr) 1976-01-08 1977-01-07 Analogues nouveaux de prostaglandines

Country Status (9)

Country Link
US (20) US4055602A (fr)
JP (1) JPS5289649A (fr)
AU (1) AU502587B2 (fr)
BE (1) BE850204A (fr)
CH (1) CH627725A5 (fr)
DE (1) DE2659215A1 (fr)
FR (1) FR2337712A1 (fr)
NL (1) NL7700117A (fr)
ZA (1) ZA767465B (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4183870A (en) * 1974-01-26 1980-01-15 May & Baker Limited Cyclopentane derivatives
US4048058A (en) * 1975-08-13 1977-09-13 Standard Oil Company (Indiana) Methods to be used in reforming processes employing multi-metallic catalysts
US4638100A (en) * 1976-01-08 1987-01-20 The Upjohn Company Aromatic or inter-oxa 2-decarboxy-2-hydroxymethyl-PGFα compounds
US4208538A (en) * 1976-01-08 1980-06-17 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-ω-phenyl-PGF2 compounds
DE2655004C3 (de) * 1976-12-02 1980-06-19 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von bicyclischen Laktonen
US5030621A (en) * 1987-04-23 1991-07-09 Bystryn Jean Claude Shed melanoma antigen compositions
US5972991A (en) * 1992-09-21 1999-10-26 Allergan Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US5688819A (en) * 1992-09-21 1997-11-18 Allergan Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5352708A (en) * 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US20030060878A1 (en) * 2001-08-31 2003-03-27 Shadduck John H. Intraocular lens system and method for power adjustment
US8048155B2 (en) 2002-02-02 2011-11-01 Powervision, Inc. Intraocular implant devices
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US7217288B2 (en) 2002-12-12 2007-05-15 Powervision, Inc. Accommodating intraocular lens having peripherally actuated deflectable surface and method
US7637947B2 (en) 2002-12-12 2009-12-29 Powervision, Inc. Accommodating intraocular lens system having spherical aberration compensation and method
US8361145B2 (en) 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
US10835373B2 (en) 2002-12-12 2020-11-17 Alcon Inc. Accommodating intraocular lenses and methods of use
AU2004219674A1 (en) 2003-03-06 2004-09-23 Powervision, Inc. Adaptive optic lens and method of making
US7306580B2 (en) * 2003-04-16 2007-12-11 Cook Incorporated Medical device with therapeutic agents
JP5215658B2 (ja) 2004-03-24 2013-06-19 ハー ツェー シュタルク インコーポレイテッド 制御される新たな微細構造を有するαタンタルフィルムおよびマイクロエレクトロニクスデバイス
US20060292324A1 (en) * 2004-03-26 2006-12-28 Robert Roberts Uniaxially and biaxially-oriented polytetrafluoroethylene structures
US7906552B2 (en) 2004-08-10 2011-03-15 Allergan, Inc. Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US7183310B2 (en) * 2004-08-10 2007-02-27 Allergan, Inc. Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US9872763B2 (en) 2004-10-22 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
WO2010102078A1 (fr) 2009-03-04 2010-09-10 Allergan, Inc. Solution ophtalmique améliorée à base de bimatoprost
US7851504B2 (en) * 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
CN101678149B (zh) 2007-02-21 2013-07-17 力景公司 适用于眼用装置的聚合材料及其制造方法
US8314927B2 (en) * 2007-07-23 2012-11-20 Powervision, Inc. Systems and methods for testing intraocular lenses
EP2178462B1 (fr) 2007-07-23 2014-04-02 PowerVision, Inc. Modification de puissance de lentille post-implant
JP5346022B2 (ja) 2007-07-23 2013-11-20 パワーヴィジョン・インコーポレーテッド 調節眼内レンズおよび使用方法
CN101754728B (zh) 2007-07-23 2013-09-18 力景公司 晶状体递送系统
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
US10299913B2 (en) 2009-01-09 2019-05-28 Powervision, Inc. Accommodating intraocular lenses and methods of use
US8476471B2 (en) 2009-07-13 2013-07-02 Irix Pharmaceuticals, Inc. Synthesis of prostanoids
EP2473138A4 (fr) * 2009-08-31 2017-08-16 PowerVision, Inc. Estimation de la taille de la capsule du cristallin
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
WO2011106435A2 (fr) 2010-02-23 2011-09-01 Powervision, Inc. Fluide pour recevoir des lentilles intraoculaires
WO2012006616A2 (fr) 2010-07-09 2012-01-12 Powervision, Inc. Dispositif de pose de lentilles intraoculaires et leurs procédés d'utilisation
JP6071995B2 (ja) 2011-03-24 2017-02-01 パワーヴィジョン・インコーポレーテッド 眼内レンズ装填システムおよび使用方法
US10433949B2 (en) 2011-11-08 2019-10-08 Powervision, Inc. Accommodating intraocular lenses
EP3785668A1 (fr) 2013-03-15 2021-03-03 Alcon Inc. Dispositifs de stockage et de chargement de lentille intra-oculaire et procédés d'utilisation
KR102311896B1 (ko) 2013-09-30 2021-10-14 패턴 에이피아이 서비시즈 인코포레이티드 복분해를 사용하는 프로스타글란딘 및 프로스타글란딘 중간체의 합성 경로
ES2962463T3 (es) 2015-06-10 2024-03-19 Alcon Inc Materiales y componentes de lentes intraoculares
CN111407464B (zh) 2015-11-06 2022-12-13 爱尔康公司 可调节人工晶状体和制造方法
AU2020357870B2 (en) 2019-10-04 2025-12-04 Alcon Inc. Adjustable intraocular lenses and methods of post-operatively adjusting intraocular lenses
BR112023018612A2 (pt) 2021-04-06 2023-10-24 Alcon Inc Aparelho, sistemas e métodos para avaliar objetivamente a acomodação em um olho

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959346A (en) * 1969-03-14 1976-05-25 The Upjohn Company Racemic prostaglandins of the 2-series and analogs thereof
DE2317019A1 (de) * 1972-04-27 1973-11-08 Upjohn Co Neue 4,5-didehydro-prostaglandine
US3914282A (en) * 1973-01-16 1975-10-21 Upjohn Co Prostaglandin E{HD 1{B , F{HD 1{B , and A{HD 1 {B analogs
US3962293A (en) * 1973-07-20 1976-06-08 The Upjohn Company 13,14-Dihydro-16-fluoro prostaglandin F1
US3932463A (en) * 1974-06-03 1976-01-13 American Cyanamid Company 11-Deoxy-13-dihydro-prostaglandin-9-ketals

Also Published As

Publication number Publication date
NL7700117A (nl) 1977-07-12
US4110384A (en) 1978-08-29
US4110383A (en) 1978-08-29
US4127733A (en) 1978-11-28
US4110382A (en) 1978-08-29
US4107212A (en) 1978-08-15
US4110381A (en) 1978-08-29
US4055602A (en) 1977-10-25
CH627725A5 (de) 1982-01-29
US4108902A (en) 1978-08-22
AU502587B2 (en) 1979-08-02
AU2077176A (en) 1978-06-29
US4111995A (en) 1978-09-05
ZA767465B (en) 1977-11-30
DE2659215A1 (de) 1977-07-21
US4111996A (en) 1978-09-05
US4113778A (en) 1978-09-12
US4107214A (en) 1978-08-15
US4107213A (en) 1978-08-15
JPS5289649A (en) 1977-07-27
US4107216A (en) 1978-08-15
US4107211A (en) 1978-08-15
FR2337712B1 (fr) 1983-05-20
FR2337712A1 (fr) 1977-08-05
US4115454A (en) 1978-09-19
US4107215A (en) 1978-08-15
US4108901A (en) 1978-08-22
US4108903A (en) 1978-08-22
US4108900A (en) 1978-08-22

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: THE UPJOHN CY

Effective date: 19860131