BE853918A - Nouvelle synthese du tetramisole, du levamidole et derives correspondants - Google Patents
Nouvelle synthese du tetramisole, du levamidole et derives correspondantsInfo
- Publication number
- BE853918A BE853918A BE176981A BE176981A BE853918A BE 853918 A BE853918 A BE 853918A BE 176981 A BE176981 A BE 176981A BE 176981 A BE176981 A BE 176981A BE 853918 A BE853918 A BE 853918A
- Authority
- BE
- Belgium
- Prior art keywords
- levamidole
- tetramisole
- corresponding derivatives
- new synthesis
- synthesis
- Prior art date
Links
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 229960001614 levamisole Drugs 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68030276A | 1976-04-26 | 1976-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE853918A true BE853918A (fr) | 1977-10-25 |
Family
ID=24730545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE176981A BE853918A (fr) | 1976-04-26 | 1977-04-25 | Nouvelle synthese du tetramisole, du levamidole et derives correspondants |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US4087611A (fr) |
| BE (1) | BE853918A (fr) |
| ZA (1) | ZA771377B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4310672A (en) * | 1976-04-26 | 1982-01-12 | American Cyanamid Co. | Synthesis of intermediates for tetramisole, levamisole and their derivatives |
| US4168381A (en) * | 1977-06-14 | 1979-09-18 | American Cyanamid Company | Enhancement of enantioselectivity by iodide salts of Rh(I) complexes in the reduction of prochiral imidazolinones |
| DE2811190A1 (de) * | 1978-03-15 | 1979-09-20 | Bayer Ag | Verfahren zur herstellung von 2-(2,2-dimethyl-3-buten-1-yl)-2-oxazolinen |
| US4216331A (en) * | 1979-02-06 | 1980-08-05 | American Cyanamid Company | Use of chiral rhodium-diphosphine catalyst capable of catalytic reduction of a tetramisole precursor to give a significant excess of the desired S-(-) isomer levamisole |
| US4459411A (en) * | 1982-09-13 | 1984-07-10 | The Dow Chemical Company | Preparation of unsaturated heterocyclic carbonyl-containing compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3726894A (en) * | 1971-06-24 | 1973-04-10 | American Cyanamid Co | The compound 1-(2-hydroxyethyl)-4-phenyl-2-imidazolidinethione |
-
1976
- 1976-11-08 US US05/739,923 patent/US4087611A/en not_active Expired - Lifetime
-
1977
- 1977-03-08 ZA ZA00771377A patent/ZA771377B/xx unknown
- 1977-04-25 BE BE176981A patent/BE853918A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4087611A (en) | 1978-05-02 |
| ZA771377B (en) | 1978-01-25 |
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