BE853919A - Nouvelle synthese non asymetrique du tetramisole du levamisole et derives correspondants - Google Patents
Nouvelle synthese non asymetrique du tetramisole du levamisole et derives correspondantsInfo
- Publication number
- BE853919A BE853919A BE176982A BE176982A BE853919A BE 853919 A BE853919 A BE 853919A BE 176982 A BE176982 A BE 176982A BE 176982 A BE176982 A BE 176982A BE 853919 A BE853919 A BE 853919A
- Authority
- BE
- Belgium
- Prior art keywords
- tetramisole
- levamisole
- new non
- corresponding derivatives
- asymmetrical synthesis
- Prior art date
Links
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 title 2
- 229960001614 levamisole Drugs 0.000 title 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68031176A | 1976-04-26 | 1976-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE853919A true BE853919A (fr) | 1977-10-25 |
Family
ID=24730593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE176982A BE853919A (fr) | 1976-04-26 | 1977-04-25 | Nouvelle synthese non asymetrique du tetramisole du levamisole et derives correspondants |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4090025A (fr) |
| BE (1) | BE853919A (fr) |
| SU (1) | SU751323A3 (fr) |
| ZA (1) | ZA771528B (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4310672A (en) * | 1976-04-26 | 1982-01-12 | American Cyanamid Co. | Synthesis of intermediates for tetramisole, levamisole and their derivatives |
| DE2963498D1 (en) * | 1978-11-06 | 1982-09-30 | American Cyanamid Co | Process for the preparation of tetramisole |
| CA1135270A (fr) * | 1978-11-06 | 1982-11-09 | American Cyanamid Company | Procedes d'obtention de tetramisole et nouveaux intermediaires |
| US4216331A (en) * | 1979-02-06 | 1980-08-05 | American Cyanamid Company | Use of chiral rhodium-diphosphine catalyst capable of catalytic reduction of a tetramisole precursor to give a significant excess of the desired S-(-) isomer levamisole |
| DE2934746A1 (de) * | 1979-08-28 | 1981-03-19 | A. Nattermann & Cie GmbH, 5000 Köln | Oxoimidazolinalkansaeuren, deren salze und ester sowie verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| US5516647A (en) * | 1993-11-05 | 1996-05-14 | Abbott Laboratories | Compounds useful as alkaline phosphatase inhibitors and therapeutic agents |
| CN101585812B (zh) * | 2009-06-17 | 2011-05-25 | 浙江工业大学 | 一种(s)型硫代咪唑啉酮类化合物的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3726894A (en) * | 1971-06-24 | 1973-04-10 | American Cyanamid Co | The compound 1-(2-hydroxyethyl)-4-phenyl-2-imidazolidinethione |
-
1976
- 1976-11-08 US US05/739,924 patent/US4090025A/en not_active Expired - Lifetime
-
1977
- 1977-03-14 ZA ZA00771528A patent/ZA771528B/xx unknown
- 1977-04-18 SU SU772469960A patent/SU751323A3/ru active
- 1977-04-25 BE BE176982A patent/BE853919A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4090025A (en) | 1978-05-16 |
| ZA771528B (en) | 1978-01-25 |
| SU751323A3 (ru) | 1980-07-23 |
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