BE855224A - Analogues de 5,6-dihydro-prostacycline et leur preparation - Google Patents

Analogues de 5,6-dihydro-prostacycline et leur preparation

Info

Publication number
BE855224A
BE855224A BE178059A BE178059A BE855224A BE 855224 A BE855224 A BE 855224A BE 178059 A BE178059 A BE 178059A BE 178059 A BE178059 A BE 178059A BE 855224 A BE855224 A BE 855224A
Authority
BE
Belgium
Prior art keywords
prostacycline
analogues
dihydro
preparation
Prior art date
Application number
BE178059A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BE855224A publication Critical patent/BE855224A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/10—Mercury compounds

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE178059A 1976-06-01 1977-05-31 Analogues de 5,6-dihydro-prostacycline et leur preparation BE855224A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69140076A 1976-06-01 1976-06-01
US69139976A 1976-06-01 1976-06-01
US78814777A 1977-04-19 1977-04-19
US78814677A 1977-04-19 1977-04-19

Publications (1)

Publication Number Publication Date
BE855224A true BE855224A (fr) 1977-11-30

Family

ID=27505431

Family Applications (1)

Application Number Title Priority Date Filing Date
BE178059A BE855224A (fr) 1976-06-01 1977-05-31 Analogues de 5,6-dihydro-prostacycline et leur preparation

Country Status (13)

Country Link
JP (1) JPS5936912B2 (fr)
AU (1) AU508891B2 (fr)
BE (1) BE855224A (fr)
CA (1) CA1196632A (fr)
CH (1) CH640847A5 (fr)
DE (1) DE2724555A1 (fr)
FR (1) FR2353543B1 (fr)
GB (1) GB1554048A (fr)
IE (1) IE45604B1 (fr)
IL (1) IL52099A (fr)
MX (1) MX4813E (fr)
NL (1) NL7705991A (fr)
SE (3) SE436744B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237060A (en) 1979-03-23 1980-12-02 Hoffmann-La Roche Inc. Prostacyclin analogs
US4297368A (en) 1976-12-31 1981-10-27 Farmitalia Carlo Erba S.P.A. Pharmaceutically useful 5,6-saturated PGI compounds

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
DE2743283A1 (de) * 1977-09-27 1979-04-05 Hoechst Ag Neue prostacyclin-analoga
DE2811950A1 (de) * 1978-03-18 1979-12-13 Hoechst Ag Neue analoga von prostacyclin
DE60023144T2 (de) 1999-08-05 2006-07-06 Teijin Ltd. Mittel zur besserung der neuropathie, die als wirkstoff stickstoffhaltige verbindungen enthalten

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1079025B (it) * 1976-05-11 1985-05-08 Wellcome Found Perfezionamento nella preparazione di eteri

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4297368A (en) 1976-12-31 1981-10-27 Farmitalia Carlo Erba S.P.A. Pharmaceutically useful 5,6-saturated PGI compounds
US4237060A (en) 1979-03-23 1980-12-02 Hoffmann-La Roche Inc. Prostacyclin analogs

Also Published As

Publication number Publication date
FR2353543A1 (fr) 1977-12-30
GB1554048A (en) 1979-10-17
CA1196632A (fr) 1985-11-12
SE8201649L (sv) 1982-03-16
IL52099A0 (en) 1977-07-31
SE7811142L (sv) 1978-11-28
MX4813E (es) 1982-10-19
NL7705991A (nl) 1977-12-05
SE436744B (sv) 1985-01-21
JPS52156854A (en) 1977-12-27
IE45604B1 (en) 1982-10-06
JPS5936912B2 (ja) 1984-09-06
SE432101B (sv) 1984-03-19
IL52099A (en) 1985-03-31
SE7706245L (sv) 1977-12-16
AU508891B2 (en) 1980-04-03
FR2353543B1 (fr) 1986-02-21
CH640847A5 (en) 1984-01-31
AU2508677A (en) 1978-11-16
DE2724555A1 (de) 1977-12-15
IE45604L (en) 1977-12-01

Similar Documents

Publication Publication Date Title
BE874202A (fr) Derives d'iminoacides cycliques et leur preparation
BE858802A (fr) Compositions d'isocyanate et leur preparation
BE833044A (fr) 4-arylpiperidines 1, 3, 4 -trisubtituees et leur preparation
BE862547A (fr) Analogues de protaglandines et leur preparation
BE857761A (fr) Analogues de prostaglandines et leur preparation
BE863702A (fr) Tetrazolylcarbamoylquinoleines et leur preparation
BE856778A (fr) Catalyseurs d'hydrosilylation et leur preparation
BE859221A (fr) Bis-carbamoylsulfures n-substitues et leur preparation
BE853949A (fr) Nouveaux derives de l'indazolyl-(4)-oxy-propanol-amine, leur preparation et utilisation
FR2353543A1 (fr) Analogues de 5,6-dihydro-prostacycline et leur preparation
FR2297203A1 (fr) Mono-hydroxybutyrates du 1,3-butanediol et leur preparation
BE854271A (fr) Analogues de prostaglandines et leur preparation
BE861351A (fr) Composes alcanoylanilides et leur preparation
BE858049A (fr) Acyloxy-n,n'-diacylmalonamides et leur mode de preparation
BE844029A (fr) Diepoxy-androstanes et leur preparation
BE875592A (fr) Derives de pyrrolidinecarboxaldehyde et de piperidinecarboxaldehyde et leur preparation
BE850552A (fr) 2-furanones et leur preparation
BE845612A (fr) Derives de tetrazole-5-carboxamide et leur preparation
BE846802A (fr) Composes de 1,3-benzodithiole-2-one et de 1,3-benzodithiole-2-thione, et leur preparation
BE850936A (fr) Hydroxyquinoleines et leur preparation
FR2307820A1 (fr) Glycosides d'echinatine et leur preparation
FR2315275A1 (fr) 1-acyl-1,2,3,4-tetrahydro-6-quinoleinols et leur preparation
BE853801A (fr) Analogues de prostaglandines et leur preparation
FR2353555A1 (fr) Esters cycliques du 1-1-bioxyde de 3,4-dihydroxy-thiafene et de la 3,4-dihydroxy-cyclopentadienone
BE832464A (fr) 3,4-dihydro-2h-isoquinoleine-1-thiones et leur preparation

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: THE UPJOHN CY

Effective date: 19870531