BE861134A - Procede de preparation d'une poudre de dissolution rapide de 7-(1-(1h)-tetrazolylacetamido)-3-(2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl) -3-cephem-4-carboxylate de sodium sterile pour administration parenterale - Google Patents

Procede de preparation d'une poudre de dissolution rapide de 7-(1-(1h)-tetrazolylacetamido)-3-(2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl) -3-cephem-4-carboxylate de sodium sterile pour administration parenterale

Info

Publication number
BE861134A
BE861134A BE1008537A BE1008537A BE861134A BE 861134 A BE861134 A BE 861134A BE 1008537 A BE1008537 A BE 1008537A BE 1008537 A BE1008537 A BE 1008537A BE 861134 A BE861134 A BE 861134A
Authority
BE
Belgium
Prior art keywords
tetrazolylacetamido
cephem
thiomethyl
thiadiazolyl
methyl
Prior art date
Application number
BE1008537A
Other languages
English (en)
Inventor
M Bornstein
M D Cise
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE861134A publication Critical patent/BE861134A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE1008537A 1976-11-24 1977-11-24 Procede de preparation d'une poudre de dissolution rapide de 7-(1-(1h)-tetrazolylacetamido)-3-(2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl) -3-cephem-4-carboxylate de sodium sterile pour administration parenterale BE861134A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74455276A 1976-11-24 1976-11-24

Publications (1)

Publication Number Publication Date
BE861134A true BE861134A (fr) 1978-05-24

Family

ID=24993135

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1008537A BE861134A (fr) 1976-11-24 1977-11-24 Procede de preparation d'une poudre de dissolution rapide de 7-(1-(1h)-tetrazolylacetamido)-3-(2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl) -3-cephem-4-carboxylate de sodium sterile pour administration parenterale

Country Status (12)

Country Link
US (1) US4146971A (fr)
JP (1) JPS6019758B2 (fr)
BE (1) BE861134A (fr)
CA (1) CA1097341A (fr)
DD (1) DD136967A5 (fr)
DE (1) DE2752443C2 (fr)
ES (1) ES464412A1 (fr)
FR (1) FR2372168A1 (fr)
GB (1) GB1589316A (fr)
IE (1) IE45994B1 (fr)
IL (1) IL53427A0 (fr)
NL (1) NL189357C (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5726692A (en) * 1980-07-22 1982-02-12 Fujisawa Pharmaceut Co Ltd Preparation of stable crystal of salt of ceftizoxime
US4458070A (en) * 1982-07-19 1984-07-03 Pfizer Inc. Process for the manufacture of crystalline sodium cefoperazone
US4456753A (en) * 1983-02-07 1984-06-26 Pfizer Inc. Process for the manufacture of highly crystalline sodium cefoperazone
FR2561916B1 (fr) * 1984-03-30 1987-12-11 Lafon Labor Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau
JPS60255723A (ja) * 1984-05-31 1985-12-17 Ono Pharmaceut Co Ltd メシル酸ガベキサートの結晶性凍結乾燥製剤及びその製造方法
DE3911321A1 (de) * 1989-04-07 1990-10-11 Hoechst Ag Verfahren zur herstellung von cefazolin-natriumsalz
TW264475B (fr) * 1991-09-20 1995-12-01 Takeda Pharm Industry Co Ltd
JPH06122630A (ja) * 1992-10-12 1994-05-06 Taiyo Yakuhin Kogyo Kk 安定な塩酸セフォチアム製剤
US6111098A (en) * 1994-05-02 2000-08-29 Shionogi & Co., Ltd. Crystal of pyrrolidylthiocarbapenem derivative, lyophilized preparation containing said crystal, and process for producing the same
RU2244716C1 (ru) * 2003-06-27 2005-01-20 Савельев Евгений Александрович Способ получения натриевой соли 7-(1-н-тетразол-1-ил)-ацетамидо-3-(2-метил-1,3,4-тиадиазол-5-ил)тиометил)- 3-цефем-4-карбоновой кислоты(цефазолина)
AU2006297289B2 (en) * 2005-09-29 2013-03-21 Novartis Ag Antibiotic formulations, unit doses, kits, and methods
CN100391961C (zh) * 2005-11-16 2008-06-04 天津大学 五水头孢唑林钠晶体结构及晶体分子组装制备方法
EP1870649A1 (fr) 2006-06-20 2007-12-26 Octapharma AG Lyophilisation visant à obtenir une humidité résiduelle déterminée par énergie de désorption aux niveaux limités
CN103751123A (zh) * 2014-01-22 2014-04-30 邓学峰 一种头孢唑林的组合药物
CN103965215B (zh) * 2014-04-30 2016-04-27 悦康药业集团有限公司 一种头孢唑林钠化合物及其无菌粉针
CN104530087B (zh) * 2014-12-25 2017-07-21 天津大学 一种头孢唑林钠新晶型及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449885A (en) * 1966-03-31 1969-06-17 Ben Venue Lab Inc Method of packaging viral antisera and other research diagnostic reagents
DE2362785A1 (de) * 1973-12-18 1975-06-26 Atmos Fritzsching & Co Gmbh Verfahren zum haltbarmachen von kristallsuspensionen
US4029655A (en) * 1975-04-11 1977-06-14 Eli Lilly And Company Method of preparing stable sterile crystalline cephalosporins for parenteral administration

Also Published As

Publication number Publication date
NL189357B (nl) 1992-10-16
NL189357C (nl) 1993-03-16
IL53427A0 (en) 1978-01-31
NL7712823A (nl) 1978-05-26
JPS5369821A (en) 1978-06-21
DD136967A5 (de) 1979-08-08
CA1097341A (fr) 1981-03-10
JPS6019758B2 (ja) 1985-05-17
DE2752443C2 (de) 1983-07-14
US4146971A (en) 1979-04-03
GB1589316A (en) 1981-05-13
FR2372168A1 (fr) 1978-06-23
DE2752443A1 (de) 1978-06-01
ES464412A1 (es) 1978-09-01
IE45994L (en) 1978-05-24
IE45994B1 (en) 1983-01-26
FR2372168B1 (fr) 1980-11-14

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19931130