BE894942A - Medicaments a haut degre de solubilite et procede pour leur obtention - Google Patents

Medicaments a haut degre de solubilite et procede pour leur obtention

Info

Publication number
BE894942A
BE894942A BE1/10635A BE1010635A BE894942A BE 894942 A BE894942 A BE 894942A BE 1/10635 A BE1/10635 A BE 1/10635A BE 1010635 A BE1010635 A BE 1010635A BE 894942 A BE894942 A BE 894942A
Authority
BE
Belgium
Prior art keywords
medicines
solubility
obtaining
solubility medicines
Prior art date
Application number
BE1/10635A
Other languages
English (en)
Original Assignee
Elan Corp Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Corp Ltd filed Critical Elan Corp Ltd
Publication of BE894942A publication Critical patent/BE894942A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
BE1/10635A 1982-04-19 1982-11-08 Medicaments a haut degre de solubilite et procede pour leur obtention BE894942A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8206646A FR2525108B1 (fr) 1982-04-19 1982-04-19 Medicaments a haut degre de solubilite et procede pour leur obtention

Publications (1)

Publication Number Publication Date
BE894942A true BE894942A (fr) 1983-05-09

Family

ID=9273120

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/10635A BE894942A (fr) 1982-04-19 1982-11-08 Medicaments a haut degre de solubilite et procede pour leur obtention

Country Status (18)

Country Link
US (2) US4610875A (fr)
JP (1) JPS58183615A (fr)
AR (1) AR230183A1 (fr)
AT (1) AT389813B (fr)
AU (1) AU555579B2 (fr)
BE (1) BE894942A (fr)
CA (1) CA1225029A (fr)
CH (1) CH655003A5 (fr)
DE (1) DE3241097A1 (fr)
ES (1) ES517444A0 (fr)
FR (1) FR2525108B1 (fr)
GB (1) GB2119784B (fr)
IE (1) IE54084B1 (fr)
IT (1) IT1153099B (fr)
LU (1) LU84468A1 (fr)
NL (1) NL8204461A (fr)
PT (1) PT75867B (fr)
SE (1) SE8206697L (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
JPS60139688A (ja) * 1983-12-28 1985-07-24 Tokyo Tanabe Co Ltd 無定形ジヒドロピリジン粉末製剤
EP0214092A1 (fr) * 1985-08-08 1987-03-11 Ciba-Geigy Ag Absorption d'aryl-2 pyrazoloquinoléines psychoactives sous forme d'une dispersion moléculaire solide dans la polyvinylpyrrolidone
US4772473A (en) * 1986-06-16 1988-09-20 Norwich Eaton Pharmaceuticals, Inc. Nitrofurantoin dosage form
US4798725A (en) * 1986-06-16 1989-01-17 Norwich Eaton Pharmaceuticals, Inc. Sustained release capsule
US4832953A (en) * 1987-08-13 1989-05-23 Alza Corporation Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix
US5264609A (en) * 1989-11-18 1993-11-23 Schering Agrochemicals Limited Preparation of propenoic acid derivatives
IT1242642B (it) * 1990-04-17 1994-05-16 Alfa Wassermann Spa Formulazioni iniettabili contenenti naproxen sale sodico.
JPH0648937A (ja) * 1992-04-07 1994-02-22 Seitai Kagaku Kenkyusho:Kk 経口投与に適する薬剤およびその製造方法
US5512300A (en) * 1992-09-15 1996-04-30 Warner-Lambert Company Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms
FR2722984B1 (fr) * 1994-07-26 1996-10-18 Effik Lab Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees
US5994348A (en) * 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
FR2736550B1 (fr) * 1995-07-14 1998-07-24 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule
US5686133A (en) * 1996-01-31 1997-11-11 Port Systems, L.L.C. Water soluble pharmaceutical coating and method for producing coated pharmaceuticals
WO1997034601A1 (fr) * 1996-03-18 1997-09-25 Eisai Co., Ltd. Compositions medicamenteuses a solubilite amelioree
US6066339A (en) * 1997-10-17 2000-05-23 Elan Corporation, Plc Oral morphine multiparticulate formulation
US6086915A (en) * 1998-04-01 2000-07-11 Bioresponse L.L.C. Compositions and methods of adjusting steroid hormone metabolism through phytochemicals
NZ509378A (en) * 1998-07-20 2003-04-29 Smithkline Beecham Corp Amorphous ammonium salts of eprosartan and pharmaceuticals thereof, useful for blocking angiotensin II receptors and useful for treating hypertension, congestive heart disease and renal failure
WO2000020033A1 (fr) * 1998-10-05 2000-04-13 Eisai Co., Ltd. Comprimes se delitant immediatement dans la cavite buccale
EP1175205B1 (fr) * 1999-11-12 2006-06-14 Abbott Laboratories Dispersion solide comrpenant ritonavir, fenofibrate ou griseofulvin
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
HUP0201450A3 (en) * 1999-12-08 2003-02-28 Pharmacia Corp Chicago Solid-state form of celecoxib having enhanced bioavailability, pharmaceutical compositions containing it and their preparation
CN1402629A (zh) 1999-12-23 2003-03-12 辉瑞产品公司 提供提高的药物浓度的药物组合物
IL134701A0 (en) * 2000-02-23 2001-04-30 J P M E D Ltd Homogeneous solid matrix containing vegetable proteins
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
WO2001095912A1 (fr) 2000-06-16 2001-12-20 Mitsubishi Pharma Corporation Compositions permettant de reguler la plage et/ou la vitesse de liberation du ph
MXPA03003685A (es) * 2000-10-24 2004-01-26 Ajinomoto Kk Preparaciones que contienen nateglinida.
CA2450748A1 (fr) * 2001-06-22 2003-01-03 Pfizer Products Inc. Compositions pharmaceutiques contenant des ensembles polymere et medicament
OA12625A (en) * 2001-06-22 2006-06-12 Pfizer Prod Inc Pharmaceutical compositions of adsorbates of amorphous drug.
EP1269994A3 (fr) * 2001-06-22 2003-02-12 Pfizer Products Inc. Compositions Pharmaceutiques comprenant un médicament et un polymère permettant d'améliorer la concentration du médicament
SI21223A (sl) * 2002-06-19 2003-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom
US20040132771A1 (en) * 2002-12-20 2004-07-08 Pfizer Inc Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
US20050152932A1 (en) * 2003-06-12 2005-07-14 Valery Normand Non-crystalline perfume or flavor delivery system
US20050048112A1 (en) 2003-08-28 2005-03-03 Jorg Breitenbach Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
EP1827429A4 (fr) * 2004-12-20 2009-08-05 Reddys Lab Ltd Dr Compositions pharmaceutiques comprenant des composes de benzimidazole amorphe
ES2384333T3 (es) * 2005-04-11 2012-07-03 Abbott Laboratories Composiciones farmacéuticas que tienen perfiles de disolución mejorados para fármacos poco solubles
WO2006119779A2 (fr) * 2005-05-10 2006-11-16 Lifecycle Pharma A/S Composition pharmaceutique comprenant un antagoniste de l'aldosterone
CA2640165A1 (fr) * 2006-01-27 2007-08-02 The Provost, Fellows And Scholars Of The College Of The Holy And Undivid Ed Trinity Of Queen Elizabeth Near Dublin Procede de production de microparticules poreuses
PT103743B (pt) * 2007-05-16 2013-01-15 Hovione Farmaciencia S A Processo para preparar derivados de 21-disódio fosfato de pregnanos.
CA2742356A1 (fr) * 2008-11-04 2010-05-14 Cipla Limited Bromure de tiotropium ayant un faible degre de cristallinite
US10463739B2 (en) * 2010-12-23 2019-11-05 AbbVie Deutschland GmbH & Co. KG Solid retard formulations based on solid dispersions
CA2837266A1 (fr) 2011-05-27 2012-12-06 Hetero Research Foundation Ritonavir amorphe co-precipite

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4151273A (en) * 1974-10-31 1979-04-24 The Regents Of The University Of California Increasing the absorption rate of insoluble drugs
JPS5163925A (ja) * 1974-11-30 1976-06-02 Kyowa Hakko Kogyo Kk Muteikeikuroramufuenikooruno seizoho
JPS51118816A (en) * 1975-04-08 1976-10-19 Meiji Seika Kaisha Ltd A process for stabilizing non-crystalloidal solid
US4127647A (en) * 1975-04-08 1978-11-28 Meiji Seika Kaisha, Ltd. Process for preparation of stable amorphous macrolide antibiotic solids
DE2634004B2 (de) * 1976-07-29 1978-08-10 Bernhard Dr. 8000 Muenchen Lippold Verfahren zur Beschleunigung der Auflösung und Verbesserung der Löslichkeit von schlechtlöslichen zur peroralen Verabreichung bestimmten Arzneistoffen
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
EP0001247A1 (fr) * 1977-09-14 1979-04-04 Kanebo, Ltd. Composition pharmaceutique contenant de la nifédipine et procédé pour sa préparation.
US4128632A (en) * 1978-02-13 1978-12-05 Merck & Co., Inc. Solubilization of Rafoxanide
US4344934A (en) * 1978-11-20 1982-08-17 American Home Products Corporation Therapeutic compositions with enhanced bioavailability
JPS587609B2 (ja) * 1979-06-17 1983-02-10 フロイント産業株式会社 粉体薬剤のコ−テング法
JPS55139319A (en) * 1979-04-13 1980-10-31 Furointo Sangyo Kk Activation of drug soluble in alkali and acid
JPS6024768B2 (ja) * 1979-06-16 1985-06-14 フロイント産業株式会社 活性化薬剤の製法
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
JPS5948810B2 (ja) * 1980-03-22 1984-11-29 山之内製薬株式会社 ニカルジピン持続性製剤用組成物
CA1146866A (fr) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Procede de production d'un compose pharmaceutique a liberation continue sous forme solide
JPS5646837A (en) * 1979-09-27 1981-04-28 Kowa Yakuhin Kogyo Kk Preparation of ibuprofen clathrate compound
JPS5655370A (en) * 1979-10-13 1981-05-15 Kyorin Pharmaceut Co Ltd Amorphous nicomol
US4327080A (en) * 1981-07-13 1982-04-27 E. R. Squibb & Sons, Inc. Novel Bendroflumethiazide formulations and method
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
DE3318649A1 (de) * 1983-05-21 1984-11-22 Bayer Ag, 5090 Leverkusen Zweiphasenformulierung

Also Published As

Publication number Publication date
IT8224368A1 (it) 1984-05-23
AT389813B (de) 1990-02-12
ES8505249A1 (es) 1985-05-16
JPH0341444B2 (fr) 1991-06-24
CH655003A5 (fr) 1986-03-27
GB2119784A (en) 1983-11-23
AU9043182A (en) 1983-10-27
FR2525108B1 (fr) 1989-05-12
NL8204461A (nl) 1983-11-16
LU84468A1 (fr) 1983-06-13
IE822610L (en) 1983-10-19
IT1153099B (it) 1987-01-14
ATA427282A (de) 1989-07-15
DE3241097A1 (de) 1983-10-20
PT75867B (fr) 1986-01-21
FR2525108A1 (fr) 1983-10-21
CA1225029A (fr) 1987-08-04
IT8224368A0 (it) 1982-11-23
IE54084B1 (en) 1989-06-07
JPS58183615A (ja) 1983-10-26
SE8206697D0 (sv) 1982-11-24
PT75867A (fr) 1982-12-01
GB2119784B (en) 1986-04-03
ES517444A0 (es) 1985-05-16
DE3241097C2 (fr) 1989-04-13
AR230183A1 (es) 1984-03-01
SE8206697L (sv) 1983-10-20
US4769236A (en) 1988-09-06
US4610875A (en) 1986-09-09
AU555579B2 (en) 1986-10-02

Similar Documents

Publication Publication Date Title
FR2525108B1 (fr) Medicaments a haut degre de solubilite et procede pour leur obtention
FR2601591B1 (fr) Preparation pharmaceutique stable contenant un facteur de stimulation de la lignee granulocytaire, et procede pour la production de celle-ci
FR2559064B1 (fr) Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer
FR2636527B1 (fr) Capsule pour medicaments
HUT51272A (en) Process for producing thiadiazin derivatives and pharmaceutical composirions containing them
OA09014A (fr) Nouveau céphème et procédé pour sa préparation.
FR2533439B1 (fr) Nouvelles compositions pharmaceutiques a base de cis-platine-ii-diammino-dichlorure et procede pour les preparer
HUT48236A (en) Process for producing 2-/azolyl-methyl/-2-aryl-1,3-dioxolanes and pharmaceutical compositions containing them
FI873389A0 (fi) Menetelmä makean tuotteen valmistamiseksi
HUT49288A (en) Process for producing nasal pharmaceutical composition
ZA814606B (en) New benzisoselenazolones process for producing the same and pharmaceutical preparations containing the same
DE3172006D1 (en) Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof
HUT47846A (en) Process for producing antimalarian pharmaceutical
FR2346324A1 (fr) Nouvelles amidino-urees, procede pour leur preparation et medicaments les renfermant
EP0290915A3 (en) Flavone-3-carboxylic-acid compounds, and process, intermediates for their preparation and medicines containing these compounds
HU906498D0 (en) Process for producing new aryloxy-alcoyl-benzenes and pharmaceutical preparatives containing these compounds
FR2572679B1 (fr) Flans optiques en polyorganoheterosiloxanes et un procede pour leur preparation
FR2440188B1 (fr) Procede de preparation de comprimes et machine a comprimer pour la realisation du procede
BE889049A (fr) Nouvelles quinoxaline-2-yl-ethenylcetones et leur procede de preparation
EP0106576A3 (en) Novel 5-membered cyclic compounds, process for production thereof, and pharmaceutical use thereof
PT87672A (pt) Process for preparing a pharmaceutical composition
FR2586681B1 (fr) Derives du methylene-dioxy-phenanthrene et du stilbene, procede pour leur preparation et medicaments les contenant
PT87287A (pt) Fused heteroalkylene quinolinamines a process and intermediates for their preparation and their use as medicaments
HU907129D0 (en) Process for producing pharmaceutical preparatives
HU904884D0 (en) Process for producing imino-substituted pyridines and pharmaceutical preparatives containing these compounds