BE897000A - Nouveaux derives de la 1,4-dihydropyridine,leur preparation et leur utilisation comme medicaments - Google Patents

Nouveaux derives de la 1,4-dihydropyridine,leur preparation et leur utilisation comme medicaments Download PDF

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Publication number
BE897000A
BE897000A BE1/10806A BE1010806A BE897000A BE 897000 A BE897000 A BE 897000A BE 1/10806 A BE1/10806 A BE 1/10806A BE 1010806 A BE1010806 A BE 1010806A BE 897000 A BE897000 A BE 897000A
Authority
BE
Belgium
Prior art keywords
isopropyl
pyridine
carboxylate
dihydropyridine
compound
Prior art date
Application number
BE1/10806A
Other languages
English (en)
French (fr)
Inventor
Arnold Vogel
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of BE897000A publication Critical patent/BE897000A/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/12Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BE1/10806A 1982-06-15 1983-06-09 Nouveaux derives de la 1,4-dihydropyridine,leur preparation et leur utilisation comme medicaments BE897000A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH369282 1982-06-15
CH369382 1982-06-15

Publications (1)

Publication Number Publication Date
BE897000A true BE897000A (fr) 1983-12-09

Family

ID=25693638

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/10806A BE897000A (fr) 1982-06-15 1983-06-09 Nouveaux derives de la 1,4-dihydropyridine,leur preparation et leur utilisation comme medicaments

Country Status (19)

Country Link
AU (1) AU1575383A (de)
BE (1) BE897000A (de)
CA (1) CA1208639A (de)
CH (1) CH660593A5 (de)
DE (1) DE3320616A1 (de)
DK (1) DK271183A (de)
ES (2) ES8504179A1 (de)
FI (1) FI832072L (de)
FR (1) FR2528431B1 (de)
GB (1) GB2122192B (de)
HU (1) HU191853B (de)
IT (1) IT1178353B (de)
NL (1) NL8302067A (de)
NZ (1) NZ204536A (de)
PH (1) PH23436A (de)
PT (1) PT76870B (de)
SE (1) SE8303385L (de)
WO (1) WO1984000033A1 (de)
ZA (1) ZA834409B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431152A1 (de) * 1984-08-24 1986-03-06 Cassella Ag, 6000 Frankfurt Verfahren zur herstellung optisch aktiver, substituierter 1,4-dihydropyridine und ihre verwendung als arzneimittel
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
DE3447169A1 (de) * 1984-12-22 1986-07-03 Bayer Ag, 5090 Leverkusen Optisch aktive nitrodihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln
US4920225A (en) * 1986-12-22 1990-04-24 Laboratoires Syntex S.A. Resolution of 1,4-dihydropyridine derivatives
DE3809912A1 (de) * 1987-03-27 1988-10-27 Byk Gulden Lomberg Chem Fab Neue zwischenprodukte zur herstellung von 1,4-dihydropyridin-3,5-dicarbonsaeurederivaten
DE4041814A1 (de) * 1990-12-24 1992-07-02 Byk Gulden Lomberg Chem Fab Verfahren zur herstellung von dihydrophyridincarbonsaeuren
US5135936A (en) * 1991-03-05 1992-08-04 Marion Merrell Dow Inc. Isomers of 1-azabicyclo[2.2.2]oct-3-yl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinediacarboxylic and their use as calcium antagonists
CN100425599C (zh) * 2005-12-31 2008-10-15 清华大学 一种有机电致发光材料及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH639659A5 (de) * 1978-12-18 1983-11-30 Sandoz Ag Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.
FI64938C (fi) * 1977-06-20 1984-02-10 Sandoz Ag Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
FI813460A7 (fi) * 1980-11-10 1982-05-11 Sandoz Ag Uusia 4-(2,1,3-bentsoksadiatsol-4-yyli)- 1,4-dihydro- pyridiinijohdannaisia, niiden valmistusmenetelmä ja niitäsisältävät farmaseuttiset yhdistelmät.

Also Published As

Publication number Publication date
ES538157A0 (es) 1986-02-01
DK271183A (da) 1983-12-16
AU1575383A (en) 1983-12-22
PH23436A (en) 1989-08-07
GB2122192B (en) 1985-12-18
IT8348488A0 (it) 1983-06-13
ES523243A0 (es) 1985-04-01
PT76870A (en) 1983-07-01
IT1178353B (it) 1987-09-09
SE8303385L (sv) 1983-12-16
FR2528431B1 (fr) 1986-01-10
FI832072A7 (fi) 1983-12-16
HU191853B (en) 1987-04-28
GB2122192A (en) 1984-01-11
DE3320616A1 (de) 1983-12-15
PT76870B (en) 1986-02-27
GB8316054D0 (en) 1983-07-20
CH660593A5 (de) 1987-05-15
ZA834409B (en) 1985-02-27
NZ204536A (en) 1986-09-10
FI832072A0 (fi) 1983-06-08
FI832072L (fi) 1983-12-16
SE8303385D0 (sv) 1983-06-14
NL8302067A (nl) 1984-01-02
ES8504179A1 (es) 1985-04-01
CA1208639A (en) 1986-07-29
DK271183D0 (da) 1983-06-13
ES8604578A1 (es) 1986-02-01
FR2528431A1 (fr) 1983-12-16
WO1984000033A1 (fr) 1984-01-05

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SANDOZ S.A.

Effective date: 19880630