ZA834409B - 1,4-dihydropyridine derivatives in optically active or in racemate form and their production and pharmaceutical compositions - Google Patents

1,4-dihydropyridine derivatives in optically active or in racemate form and their production and pharmaceutical compositions

Info

Publication number
ZA834409B
ZA834409B ZA834409A ZA834409A ZA834409B ZA 834409 B ZA834409 B ZA 834409B ZA 834409 A ZA834409 A ZA 834409A ZA 834409 A ZA834409 A ZA 834409A ZA 834409 B ZA834409 B ZA 834409B
Authority
ZA
South Africa
Prior art keywords
production
pharmaceutical compositions
optically active
dihydropyridine derivatives
racemate form
Prior art date
Application number
ZA834409A
Other languages
English (en)
Inventor
Arnold Vogel
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA834409B publication Critical patent/ZA834409B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/12—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA834409A 1982-06-15 1983-06-15 1,4-dihydropyridine derivatives in optically active or in racemate form and their production and pharmaceutical compositions ZA834409B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH369382 1982-06-15
CH369282 1982-06-15

Publications (1)

Publication Number Publication Date
ZA834409B true ZA834409B (en) 1985-02-27

Family

ID=25693638

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA834409A ZA834409B (en) 1982-06-15 1983-06-15 1,4-dihydropyridine derivatives in optically active or in racemate form and their production and pharmaceutical compositions

Country Status (19)

Country Link
AU (1) AU1575383A (de)
BE (1) BE897000A (de)
CA (1) CA1208639A (de)
CH (1) CH660593A5 (de)
DE (1) DE3320616A1 (de)
DK (1) DK271183A (de)
ES (2) ES8504179A1 (de)
FI (1) FI832072A7 (de)
FR (1) FR2528431B1 (de)
GB (1) GB2122192B (de)
HU (1) HU191853B (de)
IT (1) IT1178353B (de)
NL (1) NL8302067A (de)
NZ (1) NZ204536A (de)
PH (1) PH23436A (de)
PT (1) PT76870B (de)
SE (1) SE8303385L (de)
WO (1) WO1984000033A1 (de)
ZA (1) ZA834409B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431152A1 (de) * 1984-08-24 1986-03-06 Cassella Ag, 6000 Frankfurt Verfahren zur herstellung optisch aktiver, substituierter 1,4-dihydropyridine und ihre verwendung als arzneimittel
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
DE3447169A1 (de) * 1984-12-22 1986-07-03 Bayer Ag, 5090 Leverkusen Optisch aktive nitrodihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln
US4920225A (en) * 1986-12-22 1990-04-24 Laboratoires Syntex S.A. Resolution of 1,4-dihydropyridine derivatives
WO1988007524A1 (fr) * 1987-03-27 1988-10-06 Byk Gulden Lomberg Chemische Fabrik Gmbh Nouveaux produits intermediaires et procede
DE4041814A1 (de) * 1990-12-24 1992-07-02 Byk Gulden Lomberg Chem Fab Verfahren zur herstellung von dihydrophyridincarbonsaeuren
US5135936A (en) * 1991-03-05 1992-08-04 Marion Merrell Dow Inc. Isomers of 1-azabicyclo[2.2.2]oct-3-yl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinediacarboxylic and their use as calcium antagonists
CN100425599C (zh) * 2005-12-31 2008-10-15 清华大学 一种有机电致发光材料及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI64938C (fi) * 1977-06-20 1984-02-10 Sandoz Ag Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat
CH639659A5 (de) * 1978-12-18 1983-11-30 Sandoz Ag Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
FI813460L (fi) * 1980-11-10 1982-05-11 Sandoz Ag Nya 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-pyridinderivat deras framstaellningsfoerfarande och dessa innehaollande farmaceutiska kompositioner

Also Published As

Publication number Publication date
PH23436A (en) 1989-08-07
FI832072L (fi) 1983-12-16
GB2122192A (en) 1984-01-11
HU191853B (en) 1987-04-28
FR2528431B1 (fr) 1986-01-10
SE8303385L (sv) 1983-12-16
CH660593A5 (de) 1987-05-15
PT76870B (en) 1986-02-27
SE8303385D0 (sv) 1983-06-14
CA1208639A (en) 1986-07-29
IT1178353B (it) 1987-09-09
GB8316054D0 (en) 1983-07-20
WO1984000033A1 (fr) 1984-01-05
BE897000A (fr) 1983-12-09
ES8604578A1 (es) 1986-02-01
FR2528431A1 (fr) 1983-12-16
FI832072A0 (fi) 1983-06-08
GB2122192B (en) 1985-12-18
DK271183D0 (da) 1983-06-13
ES523243A0 (es) 1985-04-01
ES538157A0 (es) 1986-02-01
ES8504179A1 (es) 1985-04-01
PT76870A (en) 1983-07-01
DK271183A (da) 1983-12-16
NL8302067A (nl) 1984-01-02
NZ204536A (en) 1986-09-10
DE3320616A1 (de) 1983-12-15
IT8348488A0 (it) 1983-06-13
FI832072A7 (fi) 1983-12-16
AU1575383A (en) 1983-12-22

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