BE900469A - Procede de microencapsulation polyionique d'une matiere centrale sensile au sein d'une membrane semi-permeable, et capsules obtenues. - Google Patents

Procede de microencapsulation polyionique d'une matiere centrale sensile au sein d'une membrane semi-permeable, et capsules obtenues.

Info

Publication number
BE900469A
BE900469A BE0/213566A BE213566A BE900469A BE 900469 A BE900469 A BE 900469A BE 0/213566 A BE0/213566 A BE 0/213566A BE 213566 A BE213566 A BE 213566A BE 900469 A BE900469 A BE 900469A
Authority
BE
Belgium
Prior art keywords
semi
permeable membrane
polyionic
central material
microencapsulation process
Prior art date
Application number
BE0/213566A
Other languages
English (en)
Inventor
A P Jarvis Jr
Original Assignee
Damon Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Biotech Inc filed Critical Damon Biotech Inc
Publication of BE900469A publication Critical patent/BE900469A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

On met la matière centrale en suspension dans une solution aqueuse d'une matière polymère contenant des groupes cationiques (glucopolysaccharide aminé).On forme une matrice temporaire en gélifiant des gouttelettes de la suspension à l'aide d'un anion divalent ou multivalent. On réticule de façon permanente la matrice temporaire à l'aide d'une matière polymère contenant plusieurs groupes anioniques (acide polyaspartique ou polyglutamique), pour former une membrane semi-perméable.
BE0/213566A 1983-09-01 1984-08-30 Procede de microencapsulation polyionique d'une matiere centrale sensile au sein d'une membrane semi-permeable, et capsules obtenues. BE900469A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52839583A 1983-09-01 1983-09-01

Publications (1)

Publication Number Publication Date
BE900469A true BE900469A (fr) 1984-12-17

Family

ID=24105521

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/213566A BE900469A (fr) 1983-09-01 1984-08-30 Procede de microencapsulation polyionique d'une matiere centrale sensile au sein d'une membrane semi-permeable, et capsules obtenues.

Country Status (14)

Country Link
JP (1) JPS6075326A (fr)
AU (1) AU563653B2 (fr)
BE (1) BE900469A (fr)
CA (1) CA1245984A (fr)
CH (1) CH664472A5 (fr)
DE (1) DE3432143C2 (fr)
DK (1) DK419184A (fr)
FR (1) FR2551455B1 (fr)
GB (1) GB2145992B (fr)
IL (1) IL72787A (fr)
IT (1) IT1196742B (fr)
NL (1) NL8402671A (fr)
NO (1) NO843481L (fr)
SE (1) SE8404343L (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60175539A (ja) * 1984-02-23 1985-09-09 Snow Brand Milk Prod Co Ltd カプセル体およびその製造法
NO166836C (no) * 1985-03-14 1991-09-11 Univ California Fremgangsmaate for behandling av et organtransplantat.
GB8705464D0 (en) * 1987-03-09 1987-04-15 Atomic Energy Authority Uk Composite material
JPS6434436A (en) * 1987-07-28 1989-02-03 Sanyo Chemical Ind Ltd Gel cellular beads and manufacture thereof
CA1319632C (fr) * 1988-04-22 1993-06-29 Carol Louise Nolan Methode d'immobilisation microbienne
US4952618A (en) * 1988-05-03 1990-08-28 Minnesota Mining And Manufacturing Company Hydrocolloid/adhesive composition
DE3941873A1 (de) * 1989-12-19 1991-06-20 Jakob Dr Bodziony Hohlfaser mit der beschichtung von zellen, die mehrjaehrige implantation in arterien und venen ermoeglichen
DE4012079C2 (de) * 1990-04-14 1997-11-06 Jakob Dr Bodziony Implantierbare Austausch- und Diffusionskammer
US5149543A (en) * 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
US5487390A (en) * 1990-10-05 1996-01-30 Massachusetts Institute Of Technology Gas-filled polymeric microbubbles for ultrasound imaging
US5562099A (en) * 1990-10-05 1996-10-08 Massachusetts Institute Of Technology Polymeric microparticles containing agents for imaging
FR2694894B1 (fr) * 1992-08-20 1994-11-10 Coletica Utilisation d'une réaction de transacylation entre un polysaccharide estérifié et une substance polyaminée ou polyhydroxylée pour la fabrication de microparticules, procédé et composition.
FR2703927B1 (fr) * 1993-04-13 1995-07-13 Coletica Utilisation d'une réaction de transacylation entre un polysaccharide estérifié et une polyamine pour former en milieu aqueux une membrane au moins en surface de particules gélifiées.
DE4312970A1 (de) * 1993-04-21 1994-10-27 Juergen Dr Schrezenmeir Mikrokapsel sowie Verfahren und Vorrichtung zu ihrer Herstellung
DE4426396A1 (de) * 1994-07-26 1996-02-01 Ulrich Prof Dr Zimmermann Verfahren zur Herstellung konzentrierter Lösungen von mikroverkapselten Zellen oder von suspendierten Wirkstoffen in mikroverkapselter Form
US5540927A (en) * 1995-04-12 1996-07-30 Monsanto Company Microencapsulation process by coacervation
US7101575B2 (en) 1998-03-19 2006-09-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
ATE524165T1 (de) * 1998-03-19 2011-09-15 Max Planck Gesellschaft Verfahren zur herstellung von kapseln mit einer polyelektrolythülle
DE102004013637A1 (de) 2004-03-19 2005-10-13 Capsulution Nanoscience Ag Verfahren zur Herstellung von CS-Partikeln und Mikrokapseln unter Verwendung poröser Template sowie CS-Partikel und Mikrokapseln
DE102005002483A1 (de) * 2005-01-18 2006-08-03 Ehrfeld Mikrotechnik Bts Gmbh Verfahren zum Einkapseln von Sensormolekülen mit einer semipermeablen Membran
FR2986165B1 (fr) * 2012-01-31 2015-07-24 Capsum Procede de preparation de capsules rigidifiees

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
NO158284C (no) * 1981-03-13 1988-08-17 Damon Biotech Inc Fremgangsmaate for selektiv oppbrytning av en permeabel membran.

Also Published As

Publication number Publication date
DE3432143A1 (de) 1985-03-21
DK419184A (da) 1985-03-02
FR2551455B1 (fr) 1989-09-15
CH664472A5 (de) 1988-03-15
AU563653B2 (en) 1987-07-16
SE8404343L (sv) 1985-03-02
GB2145992A (en) 1985-04-11
GB2145992B (en) 1987-02-18
IT8467874A1 (it) 1986-03-03
NO843481L (no) 1985-03-04
SE8404343D0 (sv) 1984-08-31
NL8402671A (nl) 1985-04-01
CA1245984A (fr) 1988-12-06
FR2551455A1 (fr) 1985-03-08
IT1196742B (it) 1988-11-25
GB8422052D0 (en) 1984-10-03
JPS6075326A (ja) 1985-04-27
DE3432143C2 (de) 1987-05-14
IL72787A (en) 1987-12-31
IL72787A0 (en) 1984-11-30
IT8467874A0 (it) 1984-09-03
AU3263484A (en) 1985-03-07
DK419184D0 (da) 1984-08-31

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: DAMON BIOTECH INC.

Effective date: 19890831