BE902611A - Derives de 4, 5, 6, 7-tetrahydroimidazo 4, 5-c pyridine. - Google Patents

Derives de 4, 5, 6, 7-tetrahydroimidazo 4, 5-c pyridine.

Info

Publication number
BE902611A
BE902611A BE0/215149A BE215149A BE902611A BE 902611 A BE902611 A BE 902611A BE 0/215149 A BE0/215149 A BE 0/215149A BE 215149 A BE215149 A BE 215149A BE 902611 A BE902611 A BE 902611A
Authority
BE
Belgium
Prior art keywords
tetrahydroimidazo
pyridine
alkyl
derivatives
alkenyl
Prior art date
Application number
BE0/215149A
Other languages
English (en)
Inventor
U Scarponi
R De Castiglione
A Verini
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE902611A publication Critical patent/BE902611A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Dérivé de 4,5,6,7-tétrahydroimidazo/ 4,5-c /pyridine exerçant une activité antivirale et répondant à la formule générale (I) : où R1 = H ; alcényle en C2-C4, alkyle en C2-C4, alkyle en C1-C4 ou benzyle; R2, R3 et R4 = H, alcényle en C2-C4, alkyle en C1-C4, cyclo-alkyle en C3-C7, phényle ou benzyle ; R6 et R7 = H, alcényle en C2-C4, alkyle en C1-C4, cycloalkyle en C3-C7, phényle ou benzyle ; R5 = -C (O)-R2, -C(O)-OR2, R2 ou C (Y)-NH-R6 ; Y = O ou S.
BE0/215149A 1985-01-22 1985-06-07 Derives de 4, 5, 6, 7-tetrahydroimidazo 4, 5-c pyridine. BE902611A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858501542A GB8501542D0 (en) 1985-01-22 1985-01-22 4 5 6 7-tetrahydro-imidazo(4 5-clpyridine derivatives

Publications (1)

Publication Number Publication Date
BE902611A true BE902611A (fr) 1985-09-30

Family

ID=10573211

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/215149A BE902611A (fr) 1985-01-22 1985-06-07 Derives de 4, 5, 6, 7-tetrahydroimidazo 4, 5-c pyridine.

Country Status (4)

Country Link
JP (1) JPS61167687A (fr)
BE (1) BE902611A (fr)
DE (1) DE3521303A1 (fr)
GB (2) GB8501542D0 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812462A (en) * 1986-04-01 1989-03-14 Warner-Lambert Company 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid analogs having antihypertensive activity
US4816463A (en) * 1986-04-01 1989-03-28 Warner-Lambert Company Substituted diimidazo [1,5-a: 4',5'-d]pyridines having antihypertensive activity

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000042023A1 (fr) 1999-01-18 2000-07-20 Novo Nordisk A/S Imidazoles substitues, leur preparation et utilisation
US6908926B1 (en) 1999-04-16 2005-06-21 Novo Nordisk A/S Substituted imidazoles, their preparation and use
AU2002214505A1 (en) * 2000-11-09 2002-05-21 Biovitrum Ab New use of 4, 5, 6, 7-tetrahydroimidazo-(4,5-c)pyridine derivatives
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
US7247736B2 (en) 2002-12-23 2007-07-24 4Sc Ag Method of identifying inhibitors of DHODH
WO2004056746A1 (fr) 2002-12-23 2004-07-08 4Sc Ag Composes d'acide dicarboxylique de cycloalcene servant d'agents anti-inflammatoires, d'immunomodulation et anti-proliferation
US7365094B2 (en) 2002-12-23 2008-04-29 4Sc Ag Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
EP2161273B1 (fr) 2003-12-22 2015-04-15 K.U.Leuven Research & Development Composés d'Imidazo[4,5-c]pyridine et procédés de traitement anti-viral
BRPI0513811A (pt) * 2004-07-27 2008-07-15 Gilead Sciences Inc imidazo [4,5-d] pirimidinas, seus usos e processos de preparação
NZ556624A (en) 2004-12-21 2010-06-25 Gilead Sciences Inc 5-((3-(2,4-trifluoromethyphenyl)isoxazol-5-yl)methyl)-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine and method of antiviral treatment
KR101143596B1 (ko) 2006-07-07 2012-05-11 길리애드 사이언시즈, 인코포레이티드 신규의 피리다진 화합물 및 이의 용도
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
US20180200233A1 (en) * 2015-07-16 2018-07-19 Loma Linda University Compositions for preventing cancers associated with human papilloma viruses
ES2881776T3 (es) * 2016-03-08 2021-11-30 Novartis Ag Compuestos tricíclicos útiles para tratar las infecciones por ortomixovirus
JOP20170169A1 (ar) 2016-08-29 2019-01-30 Novartis Ag مركبات بيريدازين ثلاثية الحلقة مندمجة تفيد في علاج العدوى بفيروس أورثوميكسو
CN118878544A (zh) 2018-02-28 2024-11-01 诺华股份有限公司 作为正粘病毒复制抑制剂用于治疗流感的化合物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812462A (en) * 1986-04-01 1989-03-14 Warner-Lambert Company 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid analogs having antihypertensive activity
US4816463A (en) * 1986-04-01 1989-03-28 Warner-Lambert Company Substituted diimidazo [1,5-a: 4',5'-d]pyridines having antihypertensive activity

Also Published As

Publication number Publication date
GB8501542D0 (en) 1985-02-20
DE3521303A1 (de) 1985-10-31
JPS61167687A (ja) 1986-07-29
GB2158440A (en) 1985-11-13
GB2158440B (en) 1988-06-02
GB8514278D0 (en) 1985-07-10

Similar Documents

Publication Publication Date Title
BE902611A (fr) Derives de 4, 5, 6, 7-tetrahydroimidazo 4, 5-c pyridine.
ES8702787A1 (es) Procedimiento para preparar nuevos tetrahidro-benzotiazoles.
NL980043I1 (nl) Chinoline-tussenprodukten voor de synthese van 1H-imidazoc4,5-c!chinolines en 1H-imidazoc4,5-c!chinoline-4-amine.
FI852974L (fi) Nya n-hydroxylgruppen skyddande grupper och framstaellningsfoerfarande foer 3-acylamino-1-hydroxi-2-azetidinoner.
DK30488D0 (da) Steroidderivater, fremgangsmaade til fremstilling heraf samt farmacetisk middel indeholdende disse
ES8606336A1 (es) Un procedimiento para la preparacion de derivados de tiazol 2,4-disustituidos
ATE46501T1 (de) Abkoemmlinge der guanidinomethylbenzoesaeure.
PT86785A (pt) Novel naphthalene derivatives having use as antiallergy and antiinflammatory agents
DK288287A (da) Heterocycliske forbindelser samt farmaceutiske praeparater til behandling af allergiske eller inflammatoriske tilstande
ES2046229T3 (es) Composicion antiulcerosa.
DK540585D0 (da) 5-alkyl-1-phenyl-2-piperazinoalkylpyrasolin-3-on-forbindelser, fremgangsmaade til fremstilling heraf og mellemprodukter til brug herved, samt farmaceutiske praeparater indeholdende disse forbindelser
FR2367743A1 (fr) Derives aryle conten
ATE49410T1 (de) 1-aryl-5-alkoximinoalkylamino-pyrazole.
ES2038684T3 (es) Procedimiento de preparacion de derivados de octahidroindol y de compuestos intermedios de su preparacion.
NO302365B1 (no) Alkylderivater av trazodon med CNS-aktivitet
IT7849692A0 (it) Procedimento per la purificazione di urochinasi
DK197586A (da) Fremgangsmaade til fremstilling af 17alfa-ethynyl-17beta-hydroxy-18-methyl-4,15-oestradien-3-on og udgangsforbindelser til denne fremgangsmaade
DK365284A (da) 5-substituerede (1,2,4)triazolo(1,5-c)pyrimidin-2-aminer
ATE26268T1 (de) 2-alkoxyaminosulfonylbenzolsulfonyl-harnstoffderivate.
IT1174454B (it) Composti ad attivita'antidotica per la difesa di culture agrarie dall'azione di erbicidi non seletivi
DE3677465D1 (de) N-glykolylneuraminsaeurederivat.
ES8801264A1 (es) Procedimiento para la obtencion de derivados de piridazo(1,2-a)(1,2)diacepina
IT1080764B (it) Procedimento per la preparazione di un derivato dell'acetonitrile
BE901727A (fr) Derives d'hexahydroazepino 3, 4-d imidazoles.
SE8200679L (sv) 1-bensyl-4-(4-(2-pyrimidinylamino) bensyl 1-2,3-dioxopiperazinderivat, salter derav, forfarande for framstellning derav och karcinostatiska medel der de ingar

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A.

Effective date: 19920630