BE903687A - Nouveaux analogues de prostaglandines, leur preparation et les compositions pharmaceutiques qui les contiennent. - Google Patents

Nouveaux analogues de prostaglandines, leur preparation et les compositions pharmaceutiques qui les contiennent.

Info

Publication number
BE903687A
BE903687A BE0/215899A BE215899A BE903687A BE 903687 A BE903687 A BE 903687A BE 0/215899 A BE0/215899 A BE 0/215899A BE 215899 A BE215899 A BE 215899A BE 903687 A BE903687 A BE 903687A
Authority
BE
Belgium
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
prostaglandin analogs
new prostaglandin
Prior art date
Application number
BE0/215899A
Other languages
English (en)
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of BE903687A publication Critical patent/BE903687A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Analogues de prostaglandines tels que le cyclohexyl-15 dihydroxy-11, 15 méthano-6,9 oxo-5 pentanor-16, 17, 18, 19,20 prostèn, 6,6a yn-13 oate de méthyle (9S, 11R, 15S) et son diastéréoisomère (9R, 11S, 15S), le (+-)-dihydroxy-11, 15 méthano-6,9 oxo-5 prostèn-6,6a yn-13 oate de méthyle (9S, 11R), (mélange de 15 R et 15 S) et le (+-)-trihydroxy-5, 11,15 (mélange de 15 R et 15 S) méthano-6,9 prostèn-6,6a yn-13 oate de méthyle (9S, 11R),(mélange de 5 R et 5 S).
BE0/215899A 1984-11-22 1985-11-21 Nouveaux analogues de prostaglandines, leur preparation et les compositions pharmaceutiques qui les contiennent. BE903687A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848429545A GB8429545D0 (en) 1984-11-22 1984-11-22 Compositions of matter

Publications (1)

Publication Number Publication Date
BE903687A true BE903687A (fr) 1986-05-21

Family

ID=10570117

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/215899A BE903687A (fr) 1984-11-22 1985-11-21 Nouveaux analogues de prostaglandines, leur preparation et les compositions pharmaceutiques qui les contiennent.

Country Status (8)

Country Link
US (1) US4698363A (fr)
JP (1) JPS61129146A (fr)
BE (1) BE903687A (fr)
DE (1) DE3541384A1 (fr)
FR (1) FR2573422B1 (fr)
GB (2) GB8429545D0 (fr)
IT (1) IT1207509B (fr)
NL (1) NL8503213A (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0680027B2 (ja) * 1985-09-18 1994-10-12 財団法人相模中央化学研究所 プロスタサイクリン類及びこれらを含有する薬剤
HK1042654B (en) 1999-08-05 2006-01-06 Teijin Limited Neuropathy improvers containing nitrogenous compounds as the active ingredient
US6906046B2 (en) 2000-12-22 2005-06-14 Celltech R & D Inc. Pharmaceutical uses and synthesis of benzobicyclooctanes

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4192891A (en) * 1979-04-25 1980-03-11 E. R. Squibb & Sons, Inc. Prostacyclin analogs and their use in inhibition of arachidonic acid-induced platelet aggregation and bronchoconstriction
US4254041A (en) * 1979-07-05 1981-03-03 The Upjohn Company 19-Hydroxy-5-hydroxy-PGI compounds
JPS56150039A (en) * 1980-04-22 1981-11-20 Sankyo Co Ltd Clathrate compound of prostacycline derivative
US4517202A (en) * 1982-05-28 1985-05-14 May & Baker Limited Prostaglandin analogues
JPS59137445A (ja) * 1983-01-27 1984-08-07 Teijin Ltd プロスタサイクリン類及びその製法
JPS59210044A (ja) * 1983-05-13 1984-11-28 Teijin Ltd プロスタサイクリン類の製法
ES8705382A1 (es) * 1983-07-26 1987-05-01 Sankyo Co Un procedimiento para la preparacion de nuevos derivados de carbaciclina.
JPS6028943A (ja) * 1983-07-26 1985-02-14 Sankyo Co Ltd カルバサイクリン類縁体
DE3477776D1 (en) * 1983-08-19 1989-05-24 Sagami Chem Res Bicycloû3.3.0¨octane derivative and preparation thereof
JPS60202840A (ja) * 1984-03-28 1985-10-14 Sagami Chem Res Center （３’−アルコキシ−１’−アルケニル）−シス−ビシクロ〔３．３．０〕オクテン誘導体
JPS6130549A (ja) * 1984-07-23 1986-02-12 Sankyo Co Ltd ビシクロオクタン化合物
EP0171992B1 (fr) * 1984-08-09 1990-06-06 Mitsubishi Kasei Corporation Médicaments contenant la prostaglandine I2
JPS6185346A (ja) * 1984-10-03 1986-04-30 Sagami Chem Res Center ビシクロ〔３．３．０〕オクタン誘導体
JPS6185348A (ja) * 1984-10-03 1986-04-30 Sagami Chem Res Center ビシクロ〔３．３．０〕オクタノン誘導体
JPS61122292A (ja) * 1984-11-16 1986-06-10 Teijin Ltd 新規カルバサイクリン中間体の製法
JPH11539A (ja) * 1997-06-12 1999-01-06 Asahi Chem Ind Co Ltd ポリアクリロニトリル系膜およびその製造方法

Also Published As

Publication number Publication date
NL8503213A (nl) 1986-06-16
GB2167415B (en) 1989-06-07
IT1207509B (it) 1989-05-25
GB2167415A (en) 1986-05-29
GB8429545D0 (en) 1985-01-03
IT8522959A0 (it) 1985-11-22
FR2573422A1 (fr) 1986-05-23
DE3541384A1 (de) 1986-05-22
GB8528522D0 (en) 1985-12-24
JPS61129146A (ja) 1986-06-17
US4698363A (en) 1987-10-06
FR2573422B1 (fr) 1988-08-26

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: MAY & BAKER LTD

Effective date: 19891130