BG101002A - Заместени арилалкилтио-алкилтиопиридини и използване за борба с бактерии от рода helicobacter - Google Patents

Заместени арилалкилтио-алкилтиопиридини и използване за борба с бактерии от рода helicobacter

Info

Publication number
BG101002A
BG101002A BG101002A BG10100296A BG101002A BG 101002 A BG101002 A BG 101002A BG 101002 A BG101002 A BG 101002A BG 10100296 A BG10100296 A BG 10100296A BG 101002 A BG101002 A BG 101002A
Authority
BG
Bulgaria
Prior art keywords
helicobacter
arylalcillio
alkyltioperides
bacteries
substituted
Prior art date
Application number
BG101002A
Other languages
English (en)
Other versions
BG63502B1 (bg
Inventor
Guido Hanauer
Wolfgang-Alexander Simon
Peter Zimmermann
Wolfgang Opferkuch
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of BG101002A publication Critical patent/BG101002A/bg
Publication of BG63502B1 publication Critical patent/BG63502B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Air Filters, Heat-Exchange Apparatuses, And Housings Of Air-Conditioning Units (AREA)
  • Other Air-Conditioning Systems (AREA)
  • Mounting Of Printed Circuit Boards And The Like (AREA)

Abstract

Новите съединения имат формула, в която значенията на заместителите и символите са посочени в описанието. Те могат да се използват за борба с бактерии от рода Helicobacter.
BG101002A 1994-06-10 1996-11-21 Заместени арилалкилтио-алкилтиопиридини и използване за борба с бактерии от рода helicobacter BG63502B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH184594 1994-06-10
PCT/EP1995/002237 WO1995034554A1 (de) 1994-06-10 1995-06-09 Substituierte arylalkylthioalkylthiopyridine zur bekämpfung von helicobacter-bakterien

Publications (2)

Publication Number Publication Date
BG101002A true BG101002A (bg) 1997-08-29
BG63502B1 BG63502B1 (bg) 2002-03-29

Family

ID=4219963

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101002A BG63502B1 (bg) 1994-06-10 1996-11-21 Заместени арилалкилтио-алкилтиопиридини и използване за борба с бактерии от рода helicobacter

Country Status (19)

Country Link
US (1) US5859030A (bg)
EP (1) EP0764161A1 (bg)
JP (1) JPH10501254A (bg)
CN (1) CN1070488C (bg)
AU (1) AU697572B2 (bg)
BG (1) BG63502B1 (bg)
CA (1) CA2192202A1 (bg)
CZ (1) CZ288079B6 (bg)
EE (1) EE03312B1 (bg)
FI (1) FI964909A0 (bg)
HU (1) HU220062B (bg)
MX (1) MX9606300A (bg)
NO (1) NO311618B1 (bg)
NZ (1) NZ288609A (bg)
PL (1) PL181801B1 (bg)
RO (1) RO117792B1 (bg)
RU (1) RU2139286C1 (bg)
SK (1) SK281465B6 (bg)
WO (1) WO1995034554A1 (bg)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0914040A1 (en) * 1995-11-28 1999-05-12 Michael D. Wider Antimicrobial composition and methods of use therefor
US6479514B1 (en) 1998-05-23 2002-11-12 Altana Pharma Ag Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity
JP2002537336A (ja) * 1999-02-26 2002-11-05 ニトロメド インコーポレーテッド ニトロソ化およびニトロシル化されたプロトンポンプ阻害剤、組成物および使用方法
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
DE60304726T2 (de) * 2002-07-19 2007-08-09 Winston Pharmaceuticals Llc, Newport Beach Benzimidazolderivative und ihre verwendung als prodrugs für protonenpumpenhemmer
US20100317689A1 (en) * 2006-09-19 2010-12-16 Garst Michael E Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
RU2449805C1 (ru) 2011-01-27 2012-05-10 Общество С Ограниченной Ответственностью "Гармония" Пептидная фармацевтическая композиция, средство на ее основе для лечения гастродуоденальных заболеваний, вызываемых helicobacter pylori, и способ его использования
CN110294751B (zh) * 2018-03-21 2020-11-20 湖南化工研究院有限公司 具生物活性的咪唑[4,5-b]并吡啶类化合物及其制备方法和应用
CN110156752B (zh) * 2019-05-28 2021-03-19 沈阳药科大学 2-[(吡啶-2-基甲基)硫基]-1h-苯并咪唑类化合物及应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (bg) * 1968-10-21 1971-06-03
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
JPS604826B2 (ja) * 1978-09-12 1985-02-06 藤沢薬品工業株式会社 インダゾ−ル酢酸類の製造法
US4387225A (en) * 1981-01-15 1983-06-07 William H. Rorer, Inc. Heterocyclic alkylene triazinones
JPS57200386A (en) * 1981-06-04 1982-12-08 Yoshitomi Pharmaceut Ind Ltd Novel 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its salts
HU191757B (en) * 1983-05-03 1987-04-28 Byk Gulden Lomberg Chem Fab Process for producing new tricyclic ethers
JP2563619B2 (ja) * 1989-11-28 1996-12-11 株式会社東芝 ダクト用換気扇
US5504082A (en) * 1992-06-01 1996-04-02 Yoshitomi Pharmaceutical Industries, Ltd. Pyridine compound and pharmaceutical compostions
KR950701921A (ko) * 1992-06-01 1995-05-17 고야 다다시 피리딘 화합물 및 이의 제약학적 용도(pyridine compound and medicinal use thereof)
AU674058B2 (en) * 1993-02-17 1996-12-05 Altana Pharma Ag Substituted heteroarylalkylthiopyridines for controlling helicobacter bacteria
UA32583C2 (uk) * 1993-06-29 2001-02-15 Бік Гульден Ломберг Хеміше Фабрік Гмбх Похідні арилтіоалкілтіопіридину
JPH09509143A (ja) * 1993-12-01 1997-09-16 ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング 置換アミノアルキルアミノピリジン

Also Published As

Publication number Publication date
FI964909L (fi) 1996-12-09
EP0764161A1 (de) 1997-03-26
HU9603339D0 (en) 1997-01-28
MX9606300A (es) 1998-06-30
SK281465B6 (sk) 2001-04-09
US5859030A (en) 1999-01-12
CN1159803A (zh) 1997-09-17
NO311618B1 (no) 2001-12-17
BG63502B1 (bg) 2002-03-29
HUT75516A (en) 1997-05-28
NO965162L (no) 1997-02-05
EE03312B1 (et) 2000-12-15
JPH10501254A (ja) 1998-02-03
FI964909A7 (fi) 1996-12-09
NO965162D0 (no) 1996-12-03
PL181801B1 (pl) 2001-09-28
HK1001957A1 (en) 1998-07-24
PL317613A1 (en) 1997-04-14
FI964909A0 (fi) 1996-12-09
SK157696A3 (en) 1997-06-04
NZ288609A (en) 1998-12-23
HU220062B (hu) 2001-10-28
CA2192202A1 (en) 1995-12-21
RU2139286C1 (ru) 1999-10-10
WO1995034554A1 (de) 1995-12-21
CZ288079B6 (cs) 2001-04-11
RO117792B1 (ro) 2002-07-30
CN1070488C (zh) 2001-09-05
AU2790195A (en) 1996-01-05
AU697572B2 (en) 1998-10-08
CZ362496A3 (en) 1997-08-13

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