BG102171A - Derivatives of spiro [2h-1-benzopyran-2,4'-piperidin]-4(3h)-on, their acid adjuncrive salts and pharmaceutical compositions containing them - Google Patents

Derivatives of spiro [2h-1-benzopyran-2,4'-piperidin]-4(3h)-on, their acid adjuncrive salts and pharmaceutical compositions containing them

Info

Publication number: BG102171A
Authority: BG; Bulgaria
Prior art keywords: benzopyran; piperidin; derivatives; salts; acid
Prior art date: 1996-04-10

Application number

BG102171A

Other languages

Bulgarian (bg)

English (en)

Inventor

Kalman Harsanyi

Istvan Szabadkai

Istvan Borza

Egon Karpati

Bela Kiss

Margit Pellionisz

Sandor Farkas

Csilla Horvath

Katalin Csomor

Erzsebet Lapis

Istvan Laszlovszky

Sandor Szabo

Agnes Kis-Varga

Judit Laszy

Aniko Gere

Original Assignee

Richter Gedeon Vegyeszeti Gyar Rt.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-10

Filing date

1998-01-09

Publication date

1998-08-31

1998-01-09 Application filed by Richter Gedeon Vegyeszeti Gyar Rt. filed Critical Richter Gedeon Vegyeszeti Gyar Rt.

1998-08-31 Publication of BG102171A publication Critical patent/BG102171A/xx

Links

239000002253 acid Substances 0.000 title abstract 2
150000003839 salts Chemical class 0.000 title abstract 2
QHNDQKSXDVVXIB-UHFFFAOYSA-N spiro[3h-chromene-2,4'-piperidine]-4-one Chemical class O1C2=CC=CC=C2C(=O)CC21CCNCC2 QHNDQKSXDVVXIB-UHFFFAOYSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
150000001450 anions Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
208000024891 symptom Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

BG102171A 1996-04-10 1998-01-09 Derivatives of spiro [2h-1-benzopyran-2,4'-piperidin]-4(3h)-on, their acid adjuncrive salts and pharmaceutical compositions containing them BG102171A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU9600928A HUP9600928A3 (en)	1996-04-10	1996-04-10	Use of spiro[2h-1-benzopyran-2,4'-piperidin]-4(3h)-one derivatives for the preparation of pharmaceutical compositions treating dementia, novel derivatives and process for their preparation
PCT/HU1997/000012 WO1997037630A2 (en)	1996-04-10	1997-04-03	Spiro(2h-1-benzopyran-2,4'-piperidine)-4(3h)-one derivatives, acid addition salts thereof and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
BG102171A true BG102171A (en)	1998-08-31

Family

ID=89993875

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG102171A BG102171A (en)	1996-04-10	1998-01-09	Derivatives of spiro [2h-1-benzopyran-2,4'-piperidin]-4(3h)-on, their acid adjuncrive salts and pharmaceutical compositions containing them

Country Status (25)

Country	Link
US (1)	US6140336A (cs)
EP (1)	EP0863904A2 (cs)
JP (1)	JP3048068B2 (cs)
KR (1)	KR19990022807A (cs)
AU (1)	AU715104B2 (cs)
BG (1)	BG102171A (cs)
CA (1)	CA2224212A1 (cs)
CZ (1)	CZ7698A3 (cs)
EE (1)	EE9700334A (cs)
FI (1)	FI974470A7 (cs)
HU (1)	HUP9600928A3 (cs)
ID (1)	ID16582A (cs)
IL (1)	IL122542A (cs)
IS (1)	IS4632A (cs)
LT (1)	LT4417B (cs)
LV (1)	LV12017B (cs)
MD (1)	MD1837B2 (cs)
NO (1)	NO975781L (cs)
NZ (1)	NZ329359A (cs)
PL (1)	PL327412A1 (cs)
SI (1)	SI9720006A (cs)
SK (1)	SK178697A3 (cs)
TR (1)	TR199701627T1 (cs)
WO (1)	WO1997037630A2 (cs)
ZA (1)	ZA972905B (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI243173B (en) *	1999-11-17	2005-11-11	Akzo Nobel Nv	Spiro[2H-1-benzopyran-2,4'-piperidine] derivatives
ES2295963T3 (es)	2004-01-08	2008-04-16	F. Hoffmann-La Roche Ag	Derivados diaza-espiropiperidina como inhibidores del transportador 1 de glicina y transportador 2 de glicina.
WO2007088462A1 (en) *	2006-02-01	2007-08-09	Pfizer Products Inc.	Spirochromane antagonists of the h-3 receptor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2745306A1 (de) *	1977-10-07	1979-04-19	Bayer Ag	Insektizide mittel
JPS55143980A (en) *	1979-04-27	1980-11-10	Dai Ichi Seiyaku Co Ltd	Anti-allergic preparation
IL96507A0 (en) *	1989-12-08	1991-08-16	Merck & Co Inc	Nitrogen-containing spirocycles and pharmaceutical compositions containing them

1996
- 1996-04-10 HU HU9600928A patent/HUP9600928A3/hu unknown
1997
- 1997-04-03 AU AU21734/97A patent/AU715104B2/en not_active Ceased
- 1997-04-03 WO PCT/HU1997/000012 patent/WO1997037630A2/en not_active Ceased
- 1997-04-03 MD MD98-0029A patent/MD1837B2/ro unknown
- 1997-04-03 KR KR1019970709276A patent/KR19990022807A/ko not_active Withdrawn
- 1997-04-03 TR TR97/01627T patent/TR199701627T1/xx unknown
- 1997-04-03 SI SI9720006A patent/SI9720006A/sl unknown
- 1997-04-03 SK SK1786-97A patent/SK178697A3/sk unknown
- 1997-04-03 IL IL12254297A patent/IL122542A/xx active IP Right Grant
- 1997-04-03 US US08/973,612 patent/US6140336A/en not_active Expired - Fee Related
- 1997-04-03 PL PL97327412A patent/PL327412A1/xx unknown
- 1997-04-03 CA CA002224212A patent/CA2224212A1/en not_active Abandoned
- 1997-04-03 JP JP9535989A patent/JP3048068B2/ja not_active Expired - Lifetime
- 1997-04-03 EE EE9700334A patent/EE9700334A/xx unknown
- 1997-04-03 CZ CZ9876A patent/CZ7698A3/cs unknown
- 1997-04-03 EP EP97914497A patent/EP0863904A2/en not_active Withdrawn
- 1997-04-03 NZ NZ329359A patent/NZ329359A/xx unknown
- 1997-04-04 ZA ZA9702905A patent/ZA972905B/xx unknown
- 1997-04-10 ID IDP971182A patent/ID16582A/id unknown
- 1997-12-09 IS IS4632A patent/IS4632A/is unknown
- 1997-12-09 FI FI974470A patent/FI974470A7/fi unknown
- 1997-12-09 NO NO975781A patent/NO975781L/no not_active Application Discontinuation
- 1997-12-10 LT LT97-193A patent/LT4417B/lt not_active IP Right Cessation
- 1997-12-24 LV LVP-97-253A patent/LV12017B/en unknown
1998
- 1998-01-09 BG BG102171A patent/BG102171A/xx unknown

Also Published As

Publication number	Publication date
WO1997037630A2 (en)	1997-10-16
HUP9600928A3 (en)	1999-03-29
ZA972905B (en)	1997-11-03
EE9700334A (et)	1998-06-15
ID16582A (id)	1997-10-16
HUP9600928A2 (hu)	1998-05-28
NO975781L (no)	1998-02-10
NO975781D0 (no)	1997-12-09
LV12017B (en)	1998-08-20
FI974470A0 (fi)	1997-12-09
LT4417B (lt)	1998-12-28
SK178697A3 (en)	1998-06-03
IL122542A (en)	2001-01-11
PL327412A1 (en)	1998-12-07
KR19990022807A (ko)	1999-03-25
CA2224212A1 (en)	1997-10-16
CZ7698A3 (cs)	1998-04-15
MX9710029A (es)	1998-09-30
US6140336A (en)	2000-10-31
IL122542A0 (en)	1998-06-15
MD980029A (en)	1999-08-30
IS4632A (is)	1997-12-09
EP0863904A2 (en)	1998-09-16
LT97193A (en)	1998-07-27
MD1837B2 (ro)	2002-01-31
WO1997037630A3 (en)	1998-01-29
AU2173497A (en)	1997-10-29
FI974470A7 (fi)	1998-01-16
HU9600928D0 (en)	1996-05-28
AU715104B2 (en)	2000-01-13
JP3048068B2 (ja)	2000-06-05
LV12017A (lv)	1998-04-20
TR199701627T1 (xx)	1999-05-21
NZ329359A (en)	1999-05-28
SI9720006A (sl)	1998-12-31
JPH10510850A (ja)	1998-10-20

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