ES8603477A1 - Procedimiento para preparar una 1h-imidazo (4, 5-c) quinolin-4-amina - Google Patents

Procedimiento para preparar una 1h-imidazo (4, 5-c) quinolin-4-amina

Info

Publication number
ES8603477A1
ES8603477A1 ES537677A ES537677A ES8603477A1 ES 8603477 A1 ES8603477 A1 ES 8603477A1 ES 537677 A ES537677 A ES 537677A ES 537677 A ES537677 A ES 537677A ES 8603477 A1 ES8603477 A1 ES 8603477A1
Authority
ES
Spain
Prior art keywords
imidazo
quinolines
quinolin
amines
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537677A
Other languages
English (en)
Other versions
ES537677A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Riker Laboratories Inc
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of ES8603477A1 publication Critical patent/ES8603477A1/es
Publication of ES537677A0 publication Critical patent/ES537677A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Physical Water Treatments (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Alarm Systems (AREA)
  • Quinoline Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Lubricants (AREA)
  • Luminescent Compositions (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA 1H-IMIDAZO 4,5-C QUINOLIN-4-AMINA. CONSISTE EN OBTENER UN COMPUESTO (I), MEDIANTE LA CICLACION Y CONDENSACION DEL COMPUESTO (II) OBTENIENDO UN COMPUESTO INTERMEDIO, EL CUAL SE OXIDA CON UN PEROXIDO DE HIDROGENO O PERACIDO PARA OBTENER EL COMPUESTO (III) QUE POR CLORACION Y POSTERIOR TRATAMIENTO CON HIDROXIDO AMONICO O AMONIACO OBTENER EL COMPUESTO (I). ESTE COMPUESTO TIENE APLICACION FARMACOLOGICA COMO AGENTE BRONCODILATADOR Y/O ANTIVIRAL.
ES537677A 1983-11-18 1984-11-15 Procedimiento para preparar una 1h-imidazo (4, 5-c) quinolin-4-amina Granted ES537677A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55315883A 1983-11-18 1983-11-18
US55315783A 1983-11-18 1983-11-18

Publications (2)

Publication Number Publication Date
ES8603477A1 true ES8603477A1 (es) 1985-12-16
ES537677A0 ES537677A0 (es) 1985-12-16

Family

ID=27070262

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537677A Granted ES537677A0 (es) 1983-11-18 1984-11-15 Procedimiento para preparar una 1h-imidazo (4, 5-c) quinolin-4-amina

Country Status (15)

Country Link
EP (2) EP0310950B1 (es)
JP (1) JPS60123488A (es)
KR (1) KR900005657B1 (es)
AT (2) ATE49763T1 (es)
AU (2) AU581190B2 (es)
CA (1) CA1271477A (es)
DE (3) DE19975027I2 (es)
DK (6) DK164280C (es)
ES (1) ES537677A0 (es)
IE (1) IE57874B1 (es)
IL (2) IL84537A (es)
NL (2) NL980041I2 (es)
NO (7) NO163819C (es)
NZ (1) NZ210228A (es)
PH (1) PH22338A (es)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1306260C (en) 1985-10-18 1992-08-11 Shionogi & Co., Ltd. Condensed imidazopyridine derivatives
US4942168A (en) * 1987-07-13 1990-07-17 Hoechst-Roussel Pharmaceuticals Inc. Hydroxyquinoline amines, and method of enhancing memory in mammals
CA1335996C (en) * 1988-02-16 1995-06-20 Susumu Takada 2-substituted carbonylimidazo¬4,5-c|quinolines
US5019574A (en) * 1988-09-30 1991-05-28 Chugai Seiyaku Kabushiki Kaisha 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function
EP0385630B1 (en) * 1989-02-27 1996-11-27 Riker Laboratories, Inc. 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals
CA2011504C (en) * 1989-03-07 1998-06-02 Kenji Ohmori Imidazoquinolone derivatives
US4929624A (en) * 1989-03-23 1990-05-29 Minnesota Mining And Manufacturing Company Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
CA2021338C (en) * 1989-07-18 1996-07-16 Fumio Suzuki Imidazoquinolone derivatives
US4988815A (en) * 1989-10-26 1991-01-29 Riker Laboratories, Inc. 3-Amino or 3-nitro quinoline compounds which are intermediates in preparing 1H-imidazo[4,5-c]quinolines
FR2654021B1 (fr) * 1989-11-07 1992-02-28 Simond Jacques Procede de vitrification de cendres volantes et dispositif pour sa mise en óoeuvre.
GB8928281D0 (en) * 1989-12-14 1990-02-21 Smith Kline French Lab Compounds
ES2094772T3 (es) * 1990-06-01 1997-02-01 Kyowa Hakko Kogyo Kk Derivados de imidazonaftiridinas.
DE69229114T2 (de) * 1991-03-01 1999-11-04 Minnesota Mining And Mfg. Co., Saint Paul 1,2-substituierte 1h-imidazo[4,5-c]chinolin-4-amine
US5266575A (en) * 1991-11-06 1993-11-30 Minnesota Mining And Manufacturing Company 2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
IL105325A (en) * 1992-04-16 1996-11-14 Minnesota Mining & Mfg Immunogen/vaccine adjuvant composition
US5395937A (en) * 1993-01-29 1995-03-07 Minnesota Mining And Manufacturing Company Process for preparing quinoline amines
US5693811A (en) * 1996-06-21 1997-12-02 Minnesota Mining And Manufacturing Company Process for preparing tetrahdroimidazoquinolinamines
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JPH10298181A (ja) * 1997-04-25 1998-11-10 Sumitomo Pharmaceut Co Ltd タイプ２ヘルパーｔ細胞選択的免疫応答抑制剤
JP2000119271A (ja) * 1998-08-12 2000-04-25 Hokuriku Seiyaku Co Ltd １ｈ―イミダゾピリジン誘導体
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PT1539752E (pt) 2002-07-26 2007-05-31 Teva Gyogyszergyar Zartkoeruen Preparação de 1h-imidazo [4,5-c] quinolina-4-aminas via novos intermediários imidazo [4,5-c] quinolina-4-ciano e 1h-imidazo [4,5-c] quinolina-4-carboxamida
BRPI0413558A (pt) 2003-08-12 2006-10-17 3M Innovative Properties Co compostos contendo imidazo substituìdo por hidroxilamina
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EP1668010A2 (en) 2003-10-01 2006-06-14 Taro Pharmaceuticals U.S.A., Inc. Method of preparing 4-amino-1h -imidazo(4,5- c )quinolines and acid addition salts thereof
AR046046A1 (es) * 2003-10-03 2005-11-23 3M Innovative Properties Co Imidazoquinolinas alcoxi sustituidas. composiciones farmaceuticas.
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
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IL68495A0 (en) * 1982-05-03 1983-07-31 Lilly Co Eli 2-phenylimidazo(4,5-c)pyridines

Also Published As

Publication number Publication date
NO890824L (no) 1985-05-20
EP0145340A2 (en) 1985-06-19
DK542684A (da) 1985-05-19
NO168705B (no) 1991-12-16
AU581190B2 (en) 1989-02-16
NO890825L (no) 1985-05-20
CA1271477A (en) 1990-07-10
DK136191D0 (da) 1991-07-16
NO890826D0 (no) 1989-02-27
DE19975027I2 (de) 2000-09-21
DK164452C (da) 1992-11-09
ATE49763T1 (de) 1990-02-15
NO1999015I1 (no) 1999-07-08
NO169437C (no) 1992-06-24
DK135791A (da) 1991-07-16
NO890824D0 (no) 1989-02-27
IE842952L (en) 1985-05-18
JPS60123488A (ja) 1985-07-02
ATE84525T1 (de) 1993-01-15
DE3486043D1 (de) 1993-02-25
DK164451C (da) 1992-11-09
DK135991D0 (da) 1991-07-16
DK165921C (da) 1993-06-28
NO165146C (no) 1991-01-02
DK135791D0 (da) 1991-07-16
EP0145340A3 (en) 1986-06-11
DK135891A (da) 1991-07-16
NO890823L (no) 1985-05-20
DE3481124D1 (de) 1990-03-01
IL84537A0 (en) 1988-04-29
DK542684D0 (da) 1984-11-15
DK169179B1 (da) 1994-09-05
DK165921B (da) 1993-02-08
AU2991189A (en) 1989-06-15
NL980041I1 (nl) 1999-02-01
DK164280B (da) 1992-06-01
NO163819C (no) 1990-08-01
DK135891D0 (da) 1991-07-16
NO890823D0 (no) 1989-02-27
NO165147C (no) 1991-01-02
DK164280C (da) 1992-11-30
DK164451B (da) 1992-06-29
DK135991A (da) 1991-07-16
NO165147B (no) 1990-09-24
NO163819B (no) 1990-04-17
EP0310950B1 (en) 1993-01-13
NO165145B (no) 1990-09-24
JPH0586391B2 (es) 1993-12-10
DE3486043T2 (de) 1993-06-03
NO169437B (no) 1992-03-16
NO165146B (no) 1990-09-24
DK136091D0 (da) 1991-07-16
DK136191A (da) 1991-07-16
EP0310950A1 (en) 1989-04-12
DK164452B (da) 1992-06-29
NO890822D0 (no) 1989-02-27
NL980041I2 (nl) 1999-07-01
AU611997B2 (en) 1991-06-27
DK164455B (da) 1992-06-29
NO890825D0 (no) 1989-02-27
EP0145340B1 (en) 1990-01-24
NO165145C (no) 1991-01-02
ES537677A0 (es) 1985-12-16
PH22338A (en) 1988-08-12
NO890822L (no) 1985-05-20
DK164455C (da) 1992-11-16
NL980043I1 (nl) 1999-02-01
NO168705C (no) 1992-03-25
IE57874B1 (en) 1993-05-05
KR850003890A (ko) 1985-06-29
AU3540284A (en) 1985-05-23
KR900005657B1 (ko) 1990-08-03
NO844565L (no) 1985-05-20
NO890826L (no) 1985-05-20
IL84537A (en) 1990-12-23
NZ210228A (en) 1989-01-27
DK136091A (da) 1991-07-16

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