BG103106A - Таблетки тровафлоксацин мезилат - Google Patents
Таблетки тровафлоксацин мезилатInfo
- Publication number
- BG103106A BG103106A BG103106A BG10310699A BG103106A BG 103106 A BG103106 A BG 103106A BG 103106 A BG103106 A BG 103106A BG 10310699 A BG10310699 A BG 10310699A BG 103106 A BG103106 A BG 103106A
- Authority
- BG
- Bulgaria
- Prior art keywords
- tablets
- trovafloxacin mesilate
- mesilate
- trovafloxacin
- compositions
- Prior art date
Links
- 229960000497 trovafloxacin Drugs 0.000 title abstract 2
- WVPSKSLAZQPAKQ-CDMJZVDBSA-N trovafloxacin Chemical compound C([C@H]1[C@@H]([C@H]1C1)N)N1C(C(=CC=1C(=O)C(C(O)=O)=C2)F)=NC=1N2C1=CC=C(F)C=C1F WVPSKSLAZQPAKQ-CDMJZVDBSA-N 0.000 title abstract 2
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 3
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 3
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 3
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретението се отнася до състави, по-специално под формата на таблети, съдържащи полиморф II формата на тровафлоксацин мезилат, смазващо вещество имикрокристална целулоза (МС) като разтворител. Съставите, включващи МС като разтворител, имат добрастабилност при съхраняване на склад и при разтваряне. </P>
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7201398P | 1998-01-21 | 1998-01-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG103106A true BG103106A (bg) | 1999-08-31 |
Family
ID=22105016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103106A BG103106A (bg) | 1998-01-21 | 1999-01-21 | Таблетки тровафлоксацин мезилат |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6187341B1 (bg) |
| EP (1) | EP0930068A3 (bg) |
| JP (1) | JPH11269072A (bg) |
| KR (1) | KR100314977B1 (bg) |
| CN (1) | CN1227743A (bg) |
| AP (1) | AP1094A (bg) |
| AR (1) | AR012780A1 (bg) |
| AU (1) | AU758381B2 (bg) |
| BG (1) | BG103106A (bg) |
| BR (1) | BR9900116A (bg) |
| CA (1) | CA2259698C (bg) |
| CO (1) | CO4810225A1 (bg) |
| DZ (1) | DZ2712A1 (bg) |
| EA (1) | EA003247B1 (bg) |
| GT (1) | GT199900004A (bg) |
| HR (1) | HRP990023A2 (bg) |
| HU (1) | HUP9900154A3 (bg) |
| ID (1) | ID23735A (bg) |
| IL (1) | IL128051A0 (bg) |
| IS (1) | IS4947A (bg) |
| MA (1) | MA24747A1 (bg) |
| NO (1) | NO990243L (bg) |
| NZ (1) | NZ333838A (bg) |
| OA (1) | OA10958A (bg) |
| PA (1) | PA8466701A1 (bg) |
| PE (1) | PE20000169A1 (bg) |
| PL (1) | PL330981A1 (bg) |
| SG (1) | SG70666A1 (bg) |
| SK (1) | SK4299A3 (bg) |
| TN (1) | TNSN99007A1 (bg) |
| TR (1) | TR199900089A2 (bg) |
| TW (1) | TW518224B (bg) |
| YU (1) | YU2399A (bg) |
| ZA (1) | ZA99393B (bg) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200101310T2 (tr) * | 1998-11-10 | 2001-10-22 | Bayer Aktiengesellschaft | Farmasötik moksifloksasin preparatı. |
| EP1216058A2 (en) * | 1999-09-20 | 2002-06-26 | Alza Corporation | Process for lessening polymorphic conversion of a drug |
| ATE285821T1 (de) * | 1999-10-08 | 2005-01-15 | Affinium Pharm Inc | Fab i inhibitoren |
| FR2808441B1 (fr) * | 2000-05-04 | 2004-06-18 | Oreal | Utilisation de fibres dans une composition de soin ou de maquillage pour matifier la peau |
| DE10031043A1 (de) * | 2000-06-26 | 2002-02-14 | Bayer Ag | Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung |
| CA2444597A1 (en) * | 2001-04-06 | 2002-10-06 | Affinium Pharmaceuticals, Inc. | Fab i inhibitors |
| EP1396263A1 (en) | 2002-08-09 | 2004-03-10 | Warner-Lambert Company | Film coating for tablets and caplets |
| EP1575951B1 (en) | 2002-12-06 | 2014-06-25 | Debiopharm International SA | Heterocyclic compounds, methods of making them and their use in therapy |
| CN100415284C (zh) * | 2002-12-30 | 2008-09-03 | 毛友昌 | 六味木香片的制备方法 |
| DE602004016831D1 (de) | 2003-03-17 | 2008-11-13 | Affinium Pharm Inc | Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend |
| ES2297067T3 (es) * | 2003-03-19 | 2008-05-01 | The Jordanian Pharmaceutical Manufacturing Co. Ltd. | Composiciones farmaceuticas no higroscopicas que contienen acidos quinolinacarboxilicos de hidratados. |
| US8906413B2 (en) * | 2003-05-12 | 2014-12-09 | Supernus Pharmaceuticals, Inc. | Drug formulations having reduced abuse potential |
| WO2005009395A2 (en) * | 2003-07-23 | 2005-02-03 | L. Perrigo Company | Cellulosic fiber containing composition |
| EP2848614A3 (en) | 2004-06-04 | 2015-07-29 | Debiopharm International SA | Acrylamide derivatives as antibiotic agents |
| WO2006044805A2 (en) * | 2004-10-15 | 2006-04-27 | Supernus Pharmaceuticals, Inc. | Less abusable pharmaceutical preparations |
| EP1973902A2 (en) * | 2005-12-05 | 2008-10-01 | Affinium Pharmaceuticals, Inc. | 3-heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents |
| EP2687533B1 (en) | 2006-07-20 | 2017-07-19 | Debiopharm International SA | Acrylamide derivatives as FAB I inhibitors |
| WO2008098374A1 (en) | 2007-02-16 | 2008-08-21 | Affinium Pharmaceuticals, Inc. | Salts, prodrugs and polymorphs of fab i inhibitors |
| SI2861608T1 (sl) | 2012-06-19 | 2019-08-30 | Debiopharm International Sa | Derivati predzdravila (E)-N-metil-N-((3-metilbenzofuran-2-IL)metil)- 3-(7-okso-5,6,7,8-tetrahidro-1 ,8-nafthiridin-3-il)akrilamid |
| BR122023021456A2 (pt) | 2016-02-26 | 2024-02-20 | Debiopharm International S.A. | Uso de di-hidrogeno fosfato de {6- [(e)-3-{metil[(3-metil-1-benfofuran-2- iol)metil]amino)-3- oxopro-1-en-1-il]-2-oxo-3,4-di-hidro-1,8-naftiridin-1(2h)- il}metila para tratamento de osteomielite do pé diabético e composição farmacêutica |
| LT3923914T (lt) | 2019-02-14 | 2023-07-25 | Debiopharm International S.A. | Afabicino kompozicija, jos gamybos būdas |
| CN113939306B (zh) | 2019-06-14 | 2024-07-19 | 德彪药业国际股份公司 | 用于治疗涉及生物膜的细菌感染的药物及其用途 |
| JP2025529185A (ja) * | 2022-08-30 | 2025-09-04 | パンネックス セラピューティクス インコーポレイテッド | パネキシン-1調節剤及びパネキシン-1が関与する疾患の治療方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3601566A1 (de) * | 1986-01-21 | 1987-07-23 | Bayer Ag | Pharmazeutische zubereitungen von ciprofloxacin |
| US5286754A (en) | 1986-01-21 | 1994-02-15 | Bayer Aktiengesellschaft | Pharmaceutical formulations of ciprofloxacin |
| US4957554A (en) | 1989-08-16 | 1990-09-18 | Minnesota Mining And Manufacturing Company | Dimensionally-controlled ceramics |
| DE4120646A1 (de) | 1991-06-22 | 1992-12-24 | Bayer Ag | 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate |
| SK23898A3 (en) * | 1995-08-29 | 1999-05-07 | Pfizer | Zwitterionic forms of trovafloxacin |
-
1999
- 1999-01-11 PA PA19998466701A patent/PA8466701A1/es unknown
- 1999-01-13 EP EP99300258A patent/EP0930068A3/en not_active Withdrawn
- 1999-01-14 IL IL12805199A patent/IL128051A0/xx unknown
- 1999-01-14 AP APAP/P/1999/001443A patent/AP1094A/en active
- 1999-01-14 SK SK42-99A patent/SK4299A3/sk unknown
- 1999-01-14 TR TR1999/00089A patent/TR199900089A2/xx unknown
- 1999-01-15 PE PE1999000036A patent/PE20000169A1/es not_active Application Discontinuation
- 1999-01-15 MA MA25433A patent/MA24747A1/fr unknown
- 1999-01-15 GT GT199900004A patent/GT199900004A/es unknown
- 1999-01-15 ID IDP990036D patent/ID23735A/id unknown
- 1999-01-15 OA OA9900009A patent/OA10958A/en unknown
- 1999-01-19 CA CA002259698A patent/CA2259698C/en not_active Expired - Fee Related
- 1999-01-19 AR ARP990100191A patent/AR012780A1/es not_active Application Discontinuation
- 1999-01-19 BR BR9900116-0A patent/BR9900116A/pt not_active IP Right Cessation
- 1999-01-19 JP JP11010298A patent/JPH11269072A/ja active Pending
- 1999-01-19 IS IS4947A patent/IS4947A/is unknown
- 1999-01-20 KR KR1019990001589A patent/KR100314977B1/ko not_active Expired - Fee Related
- 1999-01-20 ZA ZA9900393A patent/ZA99393B/xx unknown
- 1999-01-20 NO NO990243A patent/NO990243L/no not_active Application Discontinuation
- 1999-01-20 NZ NZ333838A patent/NZ333838A/xx unknown
- 1999-01-20 HU HU9900154A patent/HUP9900154A3/hu unknown
- 1999-01-20 CN CN99101232A patent/CN1227743A/zh active Pending
- 1999-01-20 YU YU2399A patent/YU2399A/sh unknown
- 1999-01-20 AU AU12173/99A patent/AU758381B2/en not_active Ceased
- 1999-01-20 DZ DZ990013A patent/DZ2712A1/xx active
- 1999-01-20 PL PL99330981A patent/PL330981A1/xx unknown
- 1999-01-20 US US09/233,823 patent/US6187341B1/en not_active Expired - Fee Related
- 1999-01-20 SG SG1999000117A patent/SG70666A1/en unknown
- 1999-01-20 TN TNTNSN99007A patent/TNSN99007A1/fr unknown
- 1999-01-21 BG BG103106A patent/BG103106A/bg unknown
- 1999-01-21 HR HR60/072,013A patent/HRP990023A2/hr not_active Application Discontinuation
- 1999-01-21 CO CO99003190A patent/CO4810225A1/es unknown
- 1999-01-21 TW TW088100897A patent/TW518224B/zh not_active IP Right Cessation
- 1999-01-21 EA EA199900046A patent/EA003247B1/ru not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BG103106A (bg) | Таблетки тровафлоксацин мезилат | |
| TR200103186T2 (tr) | MEK enzimlerinin inhibitörleri olarak kinolin türevleri | |
| BG103413A (bg) | Производни на сулфиновата киселина, тяхното получаване и използване | |
| HK1039110A1 (zh) | 以新颖的合成物及组分作为蛋白酶抑制剂 | |
| AU2002220715A1 (en) | Indolsulfonyl compounds useful in the treatment of cns disorders | |
| GEP20033000B (en) | 2-Substituted-1-Piperidyl Benzimidazole Compounds as ORL1-Receptor Agonists | |
| DE3474631D1 (en) | N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same | |
| BG106013A (bg) | Нови съединения и състави като протеазни инхибитори | |
| AU6011301A (en) | 1,2,3,4-tetrahydroisoquinoline derivatives | |
| IS7545A (is) | 7-Arýl-3,9-díasabísýkló(3.3.1)nón-6-en afleiður og notkun þeirra sem renín hindra í meðferð á háþrýstingi, hjarta- og æða- eða nýrna sjúkdómum | |
| MY144992A (en) | Substituted 1,2,3,4-tetrahydroisoquinoline derivatives. | |
| AU2003269327A1 (en) | Tetrahydroquinoline derivatives as crth2 antagonists | |
| MY133996A (en) | Compounds for the treatment of ischemia | |
| IL114599A0 (en) | Substituted pyrimidine compounds their preparation and pharmaceutical compositions containing them | |
| HUP0103913A3 (en) | Novel form of irbesartan, methods for obtaining said form and pharmaceutical compositions containing same | |
| FI970147A0 (fi) | Triatsoliyhdisteitä ja niiden käyttö dopamiini-D3-ligandeina | |
| CA2390649A1 (en) | 5-aryl-1h-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions containing them | |
| CA2378428A1 (en) | Use of cgrp antagonists and cgrp release inhibitors for combating menopausal hot flushes | |
| BG106239A (bg) | Подобрени фармацевтични състави | |
| AU5915100A (en) | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies | |
| CA2266759A1 (en) | 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase | |
| CA2378834A1 (en) | Pyrazinones, compositions containing such compounds | |
| PT1427417E (pt) | Derivados de 6, 7-di-hidroxitetra-hidroisoquinolina substituída em 3 para utilização como agentes antibacterianos | |
| MY120550A (en) | Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols, processes for preparing them and their use as pharmaceutical compositions. | |
| MXPA02004441A (es) | Derivados de isoxazol como inhibidores de la fosfodiesterasa. |