BG106013A - Нови съединения и състави като протеазни инхибитори - Google Patents

Нови съединения и състави като протеазни инхибитори

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Publication number
BG106013A
BG106013A BG106013A BG10601301A BG106013A BG 106013 A BG106013 A BG 106013A BG 106013 A BG106013 A BG 106013A BG 10601301 A BG10601301 A BG 10601301A BG 106013 A BG106013 A BG 106013A
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BG
Bulgaria
Prior art keywords
protease inhibitors
compositions
new compounds
oxides
novel
Prior art date
Application number
BG106013A
Other languages
English (en)
Inventor
Clifford Bryant
James Palmer
Robert Rydzewski
Eduardo Setti
Zong-Qiang Tian
Shankar Venkatraman
Dan-Xiong Wang
Original Assignee
Axys Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axys Pharmaceuticals, Inc. filed Critical Axys Pharmaceuticals, Inc.
Publication of BG106013A publication Critical patent/BG106013A/bg

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Abstract

Изобретението се отнася до нови N-цианометиламидис формула I и значения на заместителите, посоченив описанието, които са цистеинпротеазни инхибитори, до техни фармацевтично приемливи соли и N-оксидите им, както и до използването им като терапевтични средства и до методи за получаването им.
BG106013A 1999-03-15 2001-10-12 Нови съединения и състави като протеазни инхибитори BG106013A (bg)

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PCT/US2000/006837 WO2000055126A2 (en) 1999-03-15 2000-03-15 N-cyanomethylamides as protease inhibitors

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