BG103207A - Esters of the arylcycloalkanecarboxylic acids, their application, pharmaceutical compositions and their preparation - Google Patents

Esters of the arylcycloalkanecarboxylic acids, their application, pharmaceutical compositions and their preparation

Info

Publication number: BG103207A
Authority: BG; Bulgaria
Prior art keywords: ring; atom; pharmaceutical compositions; optionally substituted; lower alkyl
Prior art date: 1996-07-29

Application number

BG103207A

Other languages

Bulgarian (bg)

English (en)

Inventor

Eva Akerblom

Martin Haraldsson

Rolf Johansson

Katarina Beierlein

Birger Sjoberg

Erik Ringberg

Birgitta Weinz

Original Assignee

Pharmacia Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-29

Filing date

1999-02-25

Publication date

1999-10-29

1996-07-29 Priority claimed from SE9602889A external-priority patent/SE9602889D0/xx

1996-07-29 Priority claimed from SE9602888A external-priority patent/SE9602888D0/xx

1996-07-29 Priority claimed from SE9602887A external-priority patent/SE9602887D0/xx

1996-07-29 Priority claimed from SE9602890A external-priority patent/SE9602890D0/xx

1999-02-25 Application filed by Pharmacia Ab filed Critical Pharmacia Ab

1999-10-29 Publication of BG103207A publication Critical patent/BG103207A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
150000007513 acids Chemical class 0.000 title 1
150000002148 esters Chemical class 0.000 title 1
-1 their application Substances 0.000 title 1
125000004429 atom Chemical group 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004122 cyclic group Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
125000005605 benzo group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
210000000936 intestine Anatomy 0.000 abstract 1
230000007794 irritation Effects 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
210000002700 urine Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/12—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Hydrogenated Pyridines (AREA)
Medicinal Preparation (AREA)

BG103207A 1996-07-29 1999-02-25 Esters of the arylcycloalkanecarboxylic acids, their application, pharmaceutical compositions and their preparation BG103207A (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
SE9602889A SE9602889D0 (sv)	1996-07-29	1996-07-29	Carboxylic esters, their use and preparation
SE9602888A SE9602888D0 (sv)	1996-07-29	1996-07-29	Carboxylic esters, their use and preparation
SE9602887A SE9602887D0 (sv)	1996-07-29	1996-07-29	Carboxylic esters, their use and preparation
SE9602890A SE9602890D0 (sv)	1996-07-29	1996-07-29	Carboxylic esters, their use and preparation
PCT/SE1997/001310 WO1998004517A1 (en)	1996-07-29	1997-07-23	Arylcycloalkane carboxylic esters, their use, pharmaceutical compositions and preparation

Publications (1)

Publication Number	Publication Date
BG103207A true BG103207A (en)	1999-10-29

Family

ID=27484794

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG103207A BG103207A (en)	1996-07-29	1999-02-25	Esters of the arylcycloalkanecarboxylic acids, their application, pharmaceutical compositions and their preparation

Country Status (17)

Country	Link
US (1)	US6124354A (de)
EP (1)	EP0923536A1 (de)
JP (1)	JP2000515881A (de)
KR (1)	KR20000029703A (de)
CN (1)	CN1226886A (de)
AU (1)	AU724563B2 (de)
BG (1)	BG103207A (de)
BR (1)	BR9710614A (de)
CA (1)	CA2261692A1 (de)
EE (1)	EE9900034A (de)
IL (1)	IL128096A0 (de)
NO (1)	NO990335L (de)
NZ (1)	NZ333798A (de)
PL (1)	PL331384A1 (de)
SK (1)	SK4699A3 (de)
TR (1)	TR199900185T2 (de)
WO (1)	WO1998004517A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
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PE20020547A1 (es)	2000-10-24	2002-06-12	Upjohn Co	Uso de la tolterodina en tratamientos del asma
MXPA04003806A (es) *	2001-11-05	2005-04-08	Upjohn Co	Aerosol antimuscarinico.
AU2004206846B2 (en) *	2003-01-16	2009-05-28	University Of Rochester	Quaternary antimuscarinic compounds for the treatment of bladder diseases
WO2008059239A1 (en) *	2006-11-14	2008-05-22	Astrazeneca Ab	Novel compounds 514
TW200825084A (en)	2006-11-14	2008-06-16	Astrazeneca Ab	New compounds 521
BRPI0912657A2 (pt) *	2008-05-13	2016-01-26	Astrazeneca Ab	produto farmacêutico compreendendo um antagonista de receptor muscarínico e um agonista beta2-adrenorreceptor
EA017627B1 (ru)	2008-05-13	2013-01-30	Астразенека Аб	Хинуклидиновые производные в качестве антагонистов мускаринового м3 рецептора
WO2012145234A2 (en) *	2011-04-21	2012-10-26	Emory University	Cyclopropyl derivatives and methods of use
MA37975B2 (fr)	2012-09-11	2021-03-31	Genzyme Corp	Inhibiteurs de synthase de glucosylcéramide
TW201517906A (zh)	2013-07-25	2015-05-16	Almirall Sa	含有ｍａｂａ化合物和皮質類固醇之組合
TW201617343A (zh) *	2014-09-26	2016-05-16	阿爾米雷爾有限公司	具有β２腎上腺素促效劑及Ｍ３蕈毒拮抗劑活性之新穎雙環衍生物
CN106083615B (zh) *	2016-06-08	2019-03-08	山东省药学科学院	一种盐酸环喷托酯的制备方法
US11274100B2 (en)	2017-06-21	2022-03-15	Daiichi Sankyo Company, Limited	EP300/CREBBP inhibitor
CN114040762A (zh)	2019-02-04	2022-02-11	建新公司	使用葡糖神经酰胺合酶(gcs)的抑制剂治疗纤毛疾病
GB201909709D0 (en) *	2019-07-05	2019-08-21	Univ Liverpool	Biomarkers for irritable bowel syndrome
JP2023512366A (ja)	2020-02-03	2023-03-27	ジェンザイム・コーポレーション	リソソーム蓄積性疾患と関連する神経学的症状を処置するための方法
AU2021311131B2 (en)	2020-07-24	2026-02-19	Genzyme Corporation	Pharmaceutical compositions comprising venglustat

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FR2168881A1 (en) *	1972-01-25	1973-09-07	Synthelabo	Tropanol 1-phenylcycloalkane carboxylic ester salts - spasmolytics and cholinergics
US4418202A (en) *	1981-12-21	1983-11-29	Emery Industries, Inc.	2-Vinyl- and 2-ethylcyclopropane monocarboxylates
DD289411A7 (de) *	1984-06-29	1991-05-02	Arzneimittelwerk Dresden Gmbh,De	Verfahren zur herstellung eines antidos fuer phosphororganische verbindungen
IT1228293B (it) *	1989-02-06	1991-06-07	Angeli Inst Spa	Benzoderivati di composti eterociclici contenenti azoto.
US5086054A (en) *	1990-07-31	1992-02-04	Sri International	Novel arylcycloalkanepolyalkylamines
US5064850A (en) *	1991-04-08	1991-11-12	Marion Merrell Dow Inc.	Dihydro-3,3-diphenyl-5-(1H-pyrazol-1-ylmethyl-2(3H)-furanone and dihydro-5-((substituted-1H-pyrazol-1-yl)methyl)-3,3-diphenyl-2(3H)-furanone derivatives
US5817679A (en) *	1993-04-01	1998-10-06	University Of Virginia	7-Azabicyclo 2.2.1!-heptane and -heptene derivatives as cholinergic receptor ligands

1997
- 1997-07-23 JP JP10508739A patent/JP2000515881A/ja active Pending
- 1997-07-23 US US09/230,164 patent/US6124354A/en not_active Expired - Fee Related
- 1997-07-23 EE EEP199900034A patent/EE9900034A/xx unknown
- 1997-07-23 EP EP97934832A patent/EP0923536A1/de not_active Withdrawn
- 1997-07-23 AU AU37905/97A patent/AU724563B2/en not_active Ceased
- 1997-07-23 PL PL97331384A patent/PL331384A1/xx unknown
- 1997-07-23 IL IL12809697A patent/IL128096A0/xx unknown
- 1997-07-23 TR TR1999/00185T patent/TR199900185T2/xx unknown
- 1997-07-23 SK SK46-99A patent/SK4699A3/sk unknown
- 1997-07-23 NZ NZ333798A patent/NZ333798A/xx unknown
- 1997-07-23 KR KR1019997000803A patent/KR20000029703A/ko not_active Withdrawn
- 1997-07-23 BR BR9710614-3A patent/BR9710614A/pt unknown
- 1997-07-23 WO PCT/SE1997/001310 patent/WO1998004517A1/en not_active Ceased
- 1997-07-23 CN CN97196892A patent/CN1226886A/zh active Pending
- 1997-07-23 CA CA002261692A patent/CA2261692A1/en not_active Abandoned
1999
- 1999-01-25 NO NO990335A patent/NO990335L/no not_active Application Discontinuation
- 1999-02-25 BG BG103207A patent/BG103207A/xx unknown

Also Published As

Publication number	Publication date
WO1998004517A1 (en)	1998-02-05
CA2261692A1 (en)	1998-02-05
KR20000029703A (ko)	2000-05-25
PL331384A1 (en)	1999-07-05
US6124354A (en)	2000-09-26
IL128096A0 (en)	1999-11-30
BR9710614A (pt)	2000-01-11
NO990335L (no)	1999-03-29
AU3790597A (en)	1998-02-20
CN1226886A (zh)	1999-08-25
EP0923536A1 (de)	1999-06-23
JP2000515881A (ja)	2000-11-28
NZ333798A (en)	2000-08-25
EE9900034A (et)	1999-08-16
SK4699A3 (en)	2000-04-10
AU724563B2 (en)	2000-09-28
TR199900185T2 (xx)	1999-04-21
NO990335D0 (no)	1999-01-25

Publication	Publication Date	Title
BG103207A (en)	1999-10-29	Esters of the arylcycloalkanecarboxylic acids, their application, pharmaceutical compositions and their preparation
DE3272792D1 (en)	1986-10-02	Process for the preparation of 2-penem compounds
HUP9600448A2 (hu)	1998-09-28	Naftilvegyületek, e vegyületeket tartalmazó gyógyszerkészítmények, eljárás előállításukra, intermedierjeik és alkalmazásuk
HUP9802937A2 (hu)	1999-10-28	Benzo[g]kinolin-származékok, e vegyületeket tartalmazó gyógyászati készítmények, eljárás előállításukra és alkalmazásuk
UA39936C2 (uk)	2001-07-16	2-(2,6-дифторфеніл)-4-(2-етокси-4-трет-бутилфеніл)-2-оксазолін, спосіб мiтицидної обробки та мiтицидна композиція
HUP9900851A2 (hu)	1999-09-28	Benzotiofénszármazékok felhasználása véredény simaizom sejtek migrálásának inhibiálására alkalmas gyógyszerkészítmények előállítására
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NZ503912A (en)	2002-09-27	Piperidinylaminomethyl trifluoromethyl cyclic ether compounds and their use as substance P antagonists
ES8502099A1 (es)	1984-12-16	Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.
TW429255B (en)	2001-04-11	Pyrazine compounds having treatment of central nervous system diseases and disorders
ES8606337A1 (es)	1986-04-16	Un procedimiento para preparar nuevas benzamidas con actividada antagonista de 5-ht.
TW360650B (en)	1999-06-11	Pyridin-2-ylmethyloxy-pyridin-5-ylcarbamoyl-indoline derivatives, a process for the preparation thereof, and a pharmaceutical composition comprising them
HUT35254A (en)	1985-06-28	Process for preparing new cyclobutyl-alkyl-amine compounds with pharmaceutical activity and salts thereof
HUT37431A (en)	1985-12-28	Process for the production of imidazo /1,2-c/pyrimidines and of their salts,as well as of therapeutic preparations containing these compounds as agent
UA66888C2 (uk)	2004-06-15	3-тетрагідропіридин-4-іл індоли, спосіб їх отримання та спосіб лікування психічних розладів
BG103271A (en)	2000-05-31	Derivatives of n-(benzothiazol-2-yl) piperidine-1-ethaneamines, method for their preparation and application as therapeutical means
HUP9702038A2 (hu)	1998-03-30	Fenil-szubsztituált 4-aza-szteroidok fluorszármazékai, eljárás előállításukra, alkalmazásuk, ezeket tartalmazó gyógyszerkészítmények
ZA200200009B (en)	2002-09-25	Novel fluorinated benzodioxane imidazoline derivatives, their preparation and their therapeutic applications.
ES8304973A1 (es)	1983-03-16	Un procedimiento para la preparacion de nuevos derivados de tiocarbapenem 3-sustituidos.
SE8302452D0 (sv)	1983-04-29	Method for treatment of senile dementia
DE3365933D1 (en)	1986-10-16	Substituted thienobenzodiazepinones, process for their preparation and medicines containing these compounds
WO2000008006A3 (en)	2000-08-03	Piperidine and piperazine derivatives, process for their preparation and pharmaceutical compounds containing them
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