BG103348A - Derivatives of 3-alkoxy-isoxazol-4-yl-substituted 2-amino-carboxylic acids - Google Patents

Derivatives of 3-alkoxy-isoxazol-4-yl-substituted 2-amino-carboxylic acids

Info

Publication number: BG103348A
Authority: BG; Bulgaria
Prior art keywords: group; alkyl; hydrogen; derivatives; amino
Prior art date: 1996-10-04

Application number

BG103348A

Other languages

Bulgarian (bg)

English (en)

Inventor

Benny Bang-Andersen

Klaus Bogeso

Povl Krogsgaard-Larsen

Lenz Sibylle Molten

Original Assignee

H. Lundbeck A/S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-04

Filing date

1999-03-20

Publication date

1999-11-30

1999-03-20 Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S

1999-11-30 Publication of BG103348A publication Critical patent/BG103348A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/12—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Psychology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

BG103348A 1996-10-04 1999-03-20 Derivatives of 3-alkoxy-isoxazol-4-yl-substituted 2-amino-carboxylic acids BG103348A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK109296		1996-10-04
PCT/DK1997/000426 WO1998015542A1 (en)	1996-10-04	1997-10-03	3-alkoxyisoxazol-4-yl-substituted 2-amino carboxylic acid compounds

Publications (1)

Publication Number	Publication Date
BG103348A true BG103348A (en)	1999-11-30

Family

ID=8100908

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG103348A BG103348A (en)	1996-10-04	1999-03-20	Derivatives of 3-alkoxy-isoxazol-4-yl-substituted 2-amino-carboxylic acids

Country Status (26)

Country	Link
US (1)	US6200999B1 (cs)
EP (1)	EP0934286B1 (cs)
JP (1)	JP2001501630A (cs)
KR (1)	KR20000048908A (cs)
CN (1)	CN1238766A (cs)
AR (1)	AR008880A1 (cs)
AT (1)	ATE230734T1 (cs)
AU (1)	AU733004B2 (cs)
BG (1)	BG103348A (cs)
BR (1)	BR9712198A (cs)
CA (1)	CA2268028C (cs)
CZ (1)	CZ116899A3 (cs)
DE (1)	DE69718338T2 (cs)
EA (1)	EA001625B1 (cs)
ES (1)	ES2189978T3 (cs)
HU (1)	HUP0000084A3 (cs)
IL (1)	IL129135A0 (cs)
IS (1)	IS5009A (cs)
NO (1)	NO312961B1 (cs)
NZ (1)	NZ334798A (cs)
PL (1)	PL332553A1 (cs)
SK (1)	SK42899A3 (cs)
TR (1)	TR199900724T2 (cs)
UA (1)	UA52698C2 (cs)
WO (1)	WO1998015542A1 (cs)
ZA (1)	ZA978877B (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA73749C2 (en) *	1999-11-01	2005-09-15		Diarylenines
EP1317453B1 (en) *	2000-09-15	2006-08-09	Vertex Pharmaceuticals Incorporated	Isoxazoles and their use as inhibitors of erk
US20040106794A1 (en) *	2001-04-16	2004-06-03	Schering Corporation	3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
UA78529C2 (en) *	2001-10-10	2007-04-10	Wyeth Corp	Derivatives of [[2-(amino-3,4-dioxo-1-cyclobutene-1-yl)amino]alkyl] acid for treating pain
US20040152694A1 (en) *	2003-02-04	2004-08-05	Istvan Kurucz	Methods and compositions for treating inflammatory disorders of the airways
ATE481103T1 (de)	2003-04-09	2010-10-15	Wyeth Llc	Derivate von 2-(8,9-dioxo-2,6- diazabicyclo(5.2.0)non-1(7)-en-2- yl)alkylphosphonsäure und deren verwendung als n- methyl-d-aspartat- (nmda-) rezeptorantagonisten
TW200514775A (en)	2003-10-22	2005-05-01	Wyeth Corp	Methods for the preparation of {2-[(8,9)-dioxo-2,6-diaza-bicyclo[5.2.0]-non-1(7)-en-2-yl]ethyl} phosphonic acid and esters thereof
WO2007042420A1 (en) *	2005-10-11	2007-04-19	F. Hoffmann-La Roche Ag	Isoxazole derivatives
CN102066345B (zh) *	2008-01-16	2013-07-17	生物科技研究有限公司	*唑烷衍生物作为nmda拮抗剂
EP2338492A1 (en)	2009-12-24	2011-06-29	Universidad del Pais Vasco	Methods and compositions for the treatment of alzheimer
TW201609719A (zh) *	2014-05-28	2016-03-16	美國禮來大藥廠	作為ＴＡＲＰ－γ８依賴性ＡＭＰＡ受體拮抗劑之６－經取代－３Ｈ－１，３－苯并噻唑－２－酮化合物
BR112018013541B1 (pt) *	2016-01-21	2021-12-21	Agro-Kanesho Co., Ltd.	Método para produzir um derivado do éster benzílico do ácido 2-aminonicotínico

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69102816T2 (de)	1990-05-11	1995-03-16	Sankyo Co	Piperdinyloxy- und Chinindidinyloxy- isoxazol- Derivate, ihre Herstellung und ihre therapeutische Verwendung.
DE69325662T2 (de)	1992-10-23	2000-02-10	Merck Sharp & Dohme Ltd., Hoddesdon	Dopamin rezeptor subtyp liganden
DK124393D0 (da) *	1993-11-03	1993-11-03	Lundbeck & Co As H	Compounds

1997
- 1997-03-10 UA UA99042300A patent/UA52698C2/uk unknown
- 1997-10-03 IL IL12913597A patent/IL129135A0/xx unknown
- 1997-10-03 US US09/269,356 patent/US6200999B1/en not_active Expired - Fee Related
- 1997-10-03 HU HU0000084A patent/HUP0000084A3/hu unknown
- 1997-10-03 WO PCT/DK1997/000426 patent/WO1998015542A1/en not_active Ceased
- 1997-10-03 DE DE69718338T patent/DE69718338T2/de not_active Expired - Fee Related
- 1997-10-03 AR ARP970104586A patent/AR008880A1/es not_active Application Discontinuation
- 1997-10-03 CZ CZ991168A patent/CZ116899A3/cs unknown
- 1997-10-03 EP EP97942821A patent/EP0934286B1/en not_active Expired - Lifetime
- 1997-10-03 TR TR1999/00724T patent/TR199900724T2/xx unknown
- 1997-10-03 NZ NZ334798A patent/NZ334798A/en unknown
- 1997-10-03 ES ES97942821T patent/ES2189978T3/es not_active Expired - Lifetime
- 1997-10-03 ZA ZA9708877A patent/ZA978877B/xx unknown
- 1997-10-03 AU AU44517/97A patent/AU733004B2/en not_active Ceased
- 1997-10-03 BR BR9712198-3A patent/BR9712198A/pt unknown
- 1997-10-03 AT AT97942821T patent/ATE230734T1/de not_active IP Right Cessation
- 1997-10-03 SK SK428-99A patent/SK42899A3/sk unknown
- 1997-10-03 KR KR1019990702938A patent/KR20000048908A/ko not_active Ceased
- 1997-10-03 JP JP10517096A patent/JP2001501630A/ja active Pending
- 1997-10-03 CA CA002268028A patent/CA2268028C/en not_active Expired - Fee Related
- 1997-10-03 PL PL97332553A patent/PL332553A1/xx unknown
- 1997-10-03 CN CN97180167A patent/CN1238766A/zh active Pending
- 1997-10-03 EA EA199900358A patent/EA001625B1/ru not_active IP Right Cessation
1999
- 1999-03-20 BG BG103348A patent/BG103348A/xx unknown
- 1999-03-23 IS IS5009A patent/IS5009A/is unknown
- 1999-03-30 NO NO19991561A patent/NO312961B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE230734T1 (de)	2003-01-15
WO1998015542A1 (en)	1998-04-16
NO991561D0 (no)	1999-03-30
TR199900724T2 (xx)	1999-06-21
CZ116899A3 (cs)	1999-09-15
NZ334798A (en)	2000-06-23
IS5009A (is)	1999-03-23
EP0934286A1 (en)	1999-08-11
EA199900358A1 (ru)	1999-10-28
HUP0000084A3 (en)	2001-12-28
CA2268028A1 (en)	1998-04-16
DE69718338D1 (de)	2003-02-13
US6200999B1 (en)	2001-03-13
BR9712198A (pt)	1999-08-31
AU733004B2 (en)	2001-05-03
AU4451797A (en)	1998-05-05
KR20000048908A (ko)	2000-07-25
DE69718338T2 (de)	2003-10-16
NO991561L (no)	1999-06-04
ZA978877B (en)	1998-04-17
NO312961B1 (no)	2002-07-22
CN1238766A (zh)	1999-12-15
JP2001501630A (ja)	2001-02-06
ES2189978T3 (es)	2003-07-16
AR008880A1 (es)	2000-02-23
PL332553A1 (en)	1999-09-13
EA001625B1 (ru)	2001-06-25
IL129135A0 (en)	2000-02-17
UA52698C2 (uk)	2003-01-15
SK42899A3 (en)	1999-08-06
EP0934286B1 (en)	2003-01-08
CA2268028C (en)	2003-03-18
HUP0000084A2 (hu)	2000-06-28

Publication	Publication Date	Title
BG103348A (en)	1999-11-30	Derivatives of 3-alkoxy-isoxazol-4-yl-substituted 2-amino-carboxylic acids
SG165987A1 (en)	2010-11-29	Substituted benzoxazoles and analogues as estrogenic agents
AU1620597A (en)	1997-09-18	Novel prodrugs for the therapy of tumors and inflammatory disorders
NZ310850A (en)	1999-07-29	3 alpha hydroxy(17)-unsubstituted derivatives of androstane and 21 substituted derivatives of the pregnane series and medicaments
DE69526822D1 (en)	2002-07-04	Xanthin-derivate
ATE266013T1 (de)	2004-05-15	1-phenyl-4-benzylpiperazine: spezifische liganden für den dopamin rezeptor (d4)
NZ298296A (en)	1999-11-29	Imidazo[4,5-c]quinoline amines; medicaments to induce interferon biosynthesis
BG102625A (en)	1999-04-30	Lactone derivatives of 17-beta-carboxy, carbothio and amide androstane derivatives
MX9801488A (es)	1998-11-29	Agentes de filtracion de luz.
EP0822080A3 (en)	1999-01-07	Bubble jet head and dubble jet apparatus employing the same
EP0951210A3 (en)	1999-10-27	Parts feed apparatus
DE50002708D1 (de)	2003-08-07	Kupplungssystem für den Anschluss maschinenseitiger Versorgungsleitungen für Medien aller Art inkl. elektrischer Leitungen zwischen Werkzeugmaschinen und daran angekoppeltem Werkstückträger
ES2038690T3 (es)	1993-08-01	Aminoacidos insaturados.
NO933885L (no)	1994-04-29	gsmåte
AU2001250404A1 (en)	2001-10-08	Use of dopamine-d3 receptor ligands for the treatment of diseases of the central nervous system
SE9702928D0 (sv)	1997-08-14	Stöd till pensel
TW285669B (cs)	1996-09-11
AU7522298A (en)	1998-11-13	Use of sulfonyloxadiazolones as microbicides
EP0985340A3 (en)	2001-07-04	Cleaning machine
CA2241933A1 (en)	1999-01-03	Process for preparing alkoxypyrazine derivatives
DE60010755D1 (en)	2004-06-17	Phenanthryl-piperazinyl-dicarbonsäure als selective nmda-rezeptor modulierende mittel
EP1215951A3 (en)	2005-04-20	Method and apparatus for controls of large-area ground plane potentials
TW363484U (en)	1999-07-01	Improvement on the sand paper driving system of grinding machine