BG103631A - 2-aminosubstituted pyridines applied for the treatment of atherosclerosis and hyperlipoproteinaemia - Google Patents
2-aminosubstituted pyridines applied for the treatment of atherosclerosis and hyperlipoproteinaemiaInfo
- Publication number
- BG103631A BG103631A BG103631A BG10363199A BG103631A BG 103631 A BG103631 A BG 103631A BG 103631 A BG103631 A BG 103631A BG 10363199 A BG10363199 A BG 10363199A BG 103631 A BG103631 A BG 103631A
- Authority
- BG
- Bulgaria
- Prior art keywords
- aminosubstituted
- pyridines
- atherosclerosis
- treatment
- hyperlipoproteinaemia
- Prior art date
Links
- -1 2-aminosubstituted pyridines Chemical class 0.000 title abstract 3
- 201000001320 Atherosclerosis Diseases 0.000 title abstract 2
- 208000031226 Hyperlipidaemia Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000004679 hydroxides Chemical class 0.000 abstract 1
- 150000002902 organometallic compounds Chemical class 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19704243A DE19704243A1 (de) | 1997-02-05 | 1997-02-05 | Neue 2-Amino-substituierte Pyridine |
| PCT/EP1998/000362 WO1998034920A1 (de) | 1997-02-05 | 1998-01-23 | 2-amino-substituierte pyridine verwendbar zur behandlung von arteriosklerose und hyperlipoproteinemie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG103631A true BG103631A (en) | 2000-11-30 |
Family
ID=7819326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103631A BG103631A (en) | 1997-02-05 | 1999-08-03 | 2-aminosubstituted pyridines applied for the treatment of atherosclerosis and hyperlipoproteinaemia |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0973744A1 (id) |
| JP (1) | JP2001510478A (id) |
| KR (1) | KR20000070756A (id) |
| CN (1) | CN1252057A (id) |
| AU (1) | AU730109B2 (id) |
| BG (1) | BG103631A (id) |
| BR (1) | BR9807181A (id) |
| CA (1) | CA2279636A1 (id) |
| CZ (1) | CZ279299A3 (id) |
| DE (1) | DE19704243A1 (id) |
| HU (1) | HUP0001022A2 (id) |
| ID (1) | ID24208A (id) |
| IL (1) | IL131127A0 (id) |
| NO (1) | NO993738L (id) |
| NZ (1) | NZ337011A (id) |
| PL (1) | PL334899A1 (id) |
| SK (1) | SK104099A3 (id) |
| TR (1) | TR199901857T2 (id) |
| WO (1) | WO1998034920A1 (id) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19845402B4 (de) * | 1998-10-02 | 2005-04-07 | Aventis Pharma Deutschland Gmbh | Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| JP4547148B2 (ja) | 2001-06-22 | 2010-09-22 | ベンド・リサーチ・インコーポレーテッド | 非晶質薬剤の吸着物の医薬組成物 |
| MXPA03011784A (es) | 2001-06-22 | 2004-04-02 | Pfizer Prod Inc | Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros. |
| WO2003063833A1 (en) | 2002-02-01 | 2003-08-07 | Pfizer Products Inc. | Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials |
| AU2004222436A1 (en) | 2003-03-17 | 2004-09-30 | Japan Tobacco Inc. | Method for increasing the oral bioavailability of S-(2-(((1- (2-ethylbutyl) cyclohexyl)carbonyl) amino) phenyl)-2-methylpropanethioate |
| CL2004001884A1 (es) | 2003-08-04 | 2005-06-03 | Pfizer Prod Inc | Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros. |
| MXPA06001417A (es) | 2003-08-04 | 2006-05-15 | Pfizer Prod Inc | Composiciones farmaceuticas de adsorbatos de farmacos amorfos y materiales que forman microfases lipofilas. |
| RU2330682C2 (ru) | 2003-09-26 | 2008-08-10 | Джапан Тобакко Инк. | Способ ингибирования продуцирования остаточных липопротеинов |
| DOP2005000123A (es) * | 2004-07-02 | 2011-07-15 | Merck Sharp & Dohme | Inhibidores de cetp |
| WO2006032987A1 (en) * | 2004-09-23 | 2006-03-30 | Pfizer Products Inc. | Indoline compounds and their use in the treatment of arteriosclerosis |
| EP2548894A1 (en) | 2005-02-03 | 2013-01-23 | Bend Research, Inc. | Pharmaceutical compositions with enhanced performance |
| US20100113473A1 (en) | 2008-10-30 | 2010-05-06 | Player Mark R | Aryl amide compound as an acetyl coenzyme a carboxylase inhibitor |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5169857A (en) * | 1988-01-20 | 1992-12-08 | Bayer Aktiengesellschaft | 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis |
-
1997
- 1997-02-05 DE DE19704243A patent/DE19704243A1/de not_active Withdrawn
-
1998
- 1998-01-23 SK SK1040-99A patent/SK104099A3/sk unknown
- 1998-01-23 WO PCT/EP1998/000362 patent/WO1998034920A1/de not_active Ceased
- 1998-01-23 CZ CZ992792A patent/CZ279299A3/cs unknown
- 1998-01-23 KR KR1019997007015A patent/KR20000070756A/ko not_active Withdrawn
- 1998-01-23 CA CA002279636A patent/CA2279636A1/en not_active Abandoned
- 1998-01-23 HU HU0001022A patent/HUP0001022A2/hu unknown
- 1998-01-23 TR TR1999/01857T patent/TR199901857T2/xx unknown
- 1998-01-23 IL IL13112798A patent/IL131127A0/xx unknown
- 1998-01-23 ID IDW990821D patent/ID24208A/id unknown
- 1998-01-23 BR BR9807181-5A patent/BR9807181A/pt not_active IP Right Cessation
- 1998-01-23 AU AU62123/98A patent/AU730109B2/en not_active Ceased
- 1998-01-23 JP JP53369198A patent/JP2001510478A/ja active Pending
- 1998-01-23 EP EP98904126A patent/EP0973744A1/de not_active Ceased
- 1998-01-23 NZ NZ337011A patent/NZ337011A/en unknown
- 1998-01-23 CN CN98803916A patent/CN1252057A/zh active Pending
- 1998-01-23 PL PL98334899A patent/PL334899A1/xx unknown
-
1999
- 1999-08-02 NO NO993738A patent/NO993738L/no not_active Application Discontinuation
- 1999-08-03 BG BG103631A patent/BG103631A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TR199901857T2 (xx) | 1999-10-21 |
| JP2001510478A (ja) | 2001-07-31 |
| KR20000070756A (ko) | 2000-11-25 |
| NO993738L (no) | 1999-09-17 |
| NO993738D0 (no) | 1999-08-02 |
| ID24208A (id) | 2000-07-13 |
| AU730109B2 (en) | 2001-02-22 |
| NZ337011A (en) | 2001-04-27 |
| AU6212398A (en) | 1998-08-26 |
| CN1252057A (zh) | 2000-05-03 |
| EP0973744A1 (de) | 2000-01-26 |
| WO1998034920A1 (de) | 1998-08-13 |
| CA2279636A1 (en) | 1998-08-13 |
| DE19704243A1 (de) | 1998-08-06 |
| PL334899A1 (en) | 2000-03-27 |
| HUP0001022A2 (hu) | 2000-09-28 |
| SK104099A3 (en) | 2000-01-18 |
| BR9807181A (pt) | 2000-01-25 |
| CZ279299A3 (cs) | 1999-11-17 |
| IL131127A0 (en) | 2001-01-28 |
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